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Amylyx Pharmaceuticals, Inc.

AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001658551

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

Q3 2025 vs. Q2 2025

How the institutions holding Amylyx Pharmaceuticals, Inc. changed between Q2 2025 and Q3 2025.

All holders in Q3 2025All holders in Q2 2025

13F holders of AMLX: Q2 2025 compared with Q3 2025
MeasureQ2 2025Q3 2025Change
Holders131169+38
Shares81.7M109.7M+28.0M (+34.3%)
Value$523.6M$1.49B+$967.5M (+184.8%)

New holders (57)

Institutions that held Amylyx Pharmaceuticals, Inc. at the end of Q3 2025 but not at the end of Q2 2025.

Institutions new to AMLX in Q3 2025
InstitutionSharesValue% of portfolio
Commodore Capital LP4,075,478$55.4M2.70%
First Light Asset Management, LLC3,355,882$45.6M4.30%
Janus Henderson Group PLC2,536,233$34.5M0.02%
Paradigm Biocapital Advisors LP1,900,000$25.8M0.76%
Eventide Asset Management, LLC1,512,500$20.6M0.34%
Balyasny Asset Management LLC1,476,302$20.1M0.04%
Logos Global Management LP1,450,000$19.7M1.95%
T. Rowe Price Investment Management, Inc.1,198,064$16.3M0.01%
Silverarc Capital Management, LLC700,000$9.51M1.38%
Braidwell LP612,841$8.33M0.25%
Jennison Associates LLC578,659$7.86M0.00%
Cormorant Asset Management, LP500,000$6.79M0.47%
Ally Bridge Group (NY) LLC437,391$5.94M4.98%
Acuta Capital Partners, LLC333,258$4.53M4.68%
Patient Square Capital LP316,312$4.30M1.15%
StemPoint Capital LP276,884$3.76M0.76%
Trexquant Investment LP222,876$3.03M0.03%
Longaeva Partners L.P.200,000$2.72M0.58%
SummitTX Capital, L.P.168,000$2.28M0.09%
Fred Alger Management, LLC164,042$2.23M0.01%
Diadema Partners LP100,000$1.36M0.95%
Dark Forest Capital Management LP86,795$1.18M0.04%
AQR Capital Management LLC73,640$1.00M0.00%
Maven Securities LTD70,000$951.3K0.18%
Numerai GP LLC67,153$912.6K0.13%
Verition Fund Management LLC63,896$868.3K0.00%
Readystate Asset Management LP59,132$803.6K0.04%
Brevan Howard Capital Management LP56,667$770.1K0.01%
TD Asset Management Inc40,966$556.7K0.00%
Monashee Investment Management LLC30,000$407.6K0.20%
Campbell & CO Investment Adviser LLC24,482$332.7K0.03%
Persistent Asset Partners Ltd22,913$311.4K0.23%
HSBC Holdings PLC19,369$278.1K0.00%
Oxford Asset Management LLP19,120$259.8K0.09%
EntryPoint Capital, LLC17,166$233.3K0.09%
Quantbot Technologies LP16,653$226.3K0.01%
State of Wisconsin Investment Board13,875$188.6K0.00%
Quest Partners LLC13,636$185.3K0.01%
Profund Advisors LLC13,418$182.4K0.01%
SG Americas Securities, LLC11,819$161.0K0.00%
Capstone Investment Advisors, LLC10,634$144.5K0.00%
Landscape Capital Management, L.L.C.10,401$141.3K0.01%
Point72 (DIFC) Ltd5,967$81.1K0.01%
Aster Capital Management (DIFC) Ltd3,568$48.5K0.02%
SRS Capital Advisors, Inc.2,244$30.5K0.00%
Clear Street Markets LLC1,191$16.2K0.01%
Massmutual Trust Co FSB240$3.26K0.00%
Evolution Wealth Management Inc.165$2.24K0.00%
GAMMA Investing LLC125$1.70K0.00%
Rise Advisors, LLC64$8700.00%
Jones Financial Companies LLLP30$4360.00%
Financial Consulate, Inc25$3400.00%
Farther Finance Advisors, LLC20$2720.00%
Essential Partners LLC16$2170.00%
Allworth Financial LP12$1640.00%
Rockefeller Capital Management L.P.5$680.00%
IFP Advisors, Inc1$140.00%

Sold out (19)

Institutions that held Amylyx Pharmaceuticals, Inc. at the end of Q2 2025 and filed for Q3 2025 without it.

Institutions that sold out of AMLX in Q3 2025
InstitutionShares, Q2 2025Value, Q2 2025
Standard Life Aberdeen plc738,657$4.73M
J. Goldman & Co LP258,600$1.66M
Y-Intercept (Hong Kong) Ltd240,379$1.54M
Jane Street Group, LLC186,986$1.20M
American Century Companies Inc134,380$861.4K
Allostery Investments LP120,119$770.0K
Susquehanna International Group, LLP110,846$710.5K
Cantor Fitzgerald, L. P.50,000$320.5K
Jump Financial, LLC47,800$306.4K
Centiva Capital, LP45,464$291.4K
Squarepoint Ops LLC40,643$260.5K
Graham Capital Management, L.P.34,153$218.9K
Group One Trading, L.P.25,856$165.7K
Bridgeway Capital Management, LLC25,700$164.7K
Los Angeles Capital Management LLC23,320$149.5K
Marex Group plc20,000$128.2K
Tudor Investment Corp Et Al12,073$77.4K
Raymond James Financial Inc104$667
Skopos Labs, Inc.42$270