Agios Pharmaceuticals, Inc.
AGIO- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001439222
In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 2 sales; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Agios Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 234
- −1 vs. Q4 2025
- Shares held
- 63.1M
- +7.41M (+13.3%) vs. Q4 2025
- Total value
- $2.12B
- +$605.4M (+40.0%) vs. Q4 2025
- New holders
- 36
- 82 more added
- Sold out
- 37
- 82 more reduced
3 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AGIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 238 | $2.45B |
| Q1 2026 | 234 | $2.12B |
| Q4 2025 | 238 | $1.67B |
| Q3 2025 | 221 | $2.55B |
| Q2 2025 | 216 | $2.05B |
| Q1 2025 | 221 | $1.76B |
| Q4 2024 | 225 | $1.97B |
| Q3 2024 | 208 | $2.58B |
| Q2 2024 | 206 | $2.51B |
| Q1 2024 | 187 | $1.81B |
| Q4 2023 | 170 | $1.33B |
| Q3 2023 | 146 | $1.46B |
| Q2 2023 | 153 | $1.68B |
| Q1 2023 | 165 | $1.36B |
| Q4 2022 | 160 | $1.67B |
| Q3 2022 | 168 | $1.64B |
| Q2 2022 | 157 | $1.31B |
| Q1 2022 | 161 | $1.74B |
| Q4 2021 | 161 | $1.95B |
| Q3 2021 | 165 | $2.81B |
| Q2 2021 | 186 | $3.63B |
| Q1 2021 | 175 | $3.37B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Agios Pharmaceuticals, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| CWM Advisors, LLC | 14,740 | $498.7K | 0.03% | −2,375−13.9% | Reduced |
| Rockefeller Capital Management L.P. | 14,875 | $503.2K | 0.00% | −6,196−29.4% | Reduced |
| PSP Research LLC | 15,000 | $507.4K | 0.36% | +15,000 | New |
| Arizona State Retirement System | 15,161 | $512.9K | 0.00% | −169−1.1% | Reduced |
| Diversified Trust Co | 15,319 | $518.2K | 0.01% | +6,157+67.2% | Added |
| Police & Firemen's Retirement System of New Jersey | 15,640 | $529.1K | 0.00% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 15,847 | $536.1K | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 16,222 | $548.8K | 0.10% | +9,482+140.7% | Added |
| Citigroup Inc | 17,096 | $578.4K | 0.00% | −71,142−80.6% | Reduced |
| CenterBook Partners LP | 17,445 | $590.2K | 0.03% | +17,445 | New |
| Balyasny Asset Management LLC | 18,009 | $609.2K | 0.00% | −617,060−97.2% | Reduced |
| State of New Jersey Common Pension Fund D | 18,864 | $638.2K | 0.00% | −28,550−60.2% | Reduced |
| Victory Capital Management Inc | 19,115 | $646.7K | 0.00% | −8,582−31.0% | Reduced |
| Handelsbanken Fonder AB | 19,323 | $654.0K | 0.00% | 00.0% | Unchanged |
| Virtu Financial LLC | 21,392 | $724.0K | 0.03% | +21,392 | New |
| Wells Fargo & Company | 22,763 | $770.1K | 0.00% | −42,009−64.9% | Reduced |
| Vanguard Global Advisers, LLC | 23,352 | $790.0K | 0.00% | +23,352 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 23,620 | $799.1K | 0.00% | 00.0% | Unchanged |
| TD Asset Management Inc | 23,732 | $802.9K | 0.00% | −33,560−58.6% | Reduced |
| Janus Henderson Group PLC | 23,797 | $804.7K | 0.00% | 00.0% | Unchanged |
| Canada Pension Plan Investment Board | 24,400 | $825.5K | 0.00% | +6,200+34.1% | Added |
| Oak Ridge Investments LLC | 24,865 | $841.2K | 0.06% | +4,861+24.3% | Added |
| Brevan Howard Capital Management LP | 24,469 | $866.6K | 0.01% | +5,133+26.5% | Added |
| Quantinno Capital Management LP | 27,591 | $933.4K | 0.00% | +736+2.7% | Added |
| State of Wisconsin Investment Board | 27,810 | $940.8K | 0.00% | −6,827−19.7% | Reduced |
| Jacobs Levy Equity Management, Inc | 28,530 | $965.2K | 0.00% | −82,620−74.3% | Reduced |
| Engineers Gate Manager LP | 28,920 | $978.4K | 0.01% | −20,208−41.1% | Reduced |
| Prelude Capital Management, LLC | 29,085 | $983.9K | 0.08% | −4,600−13.7% | Reduced |
| Virtus Investment Advisers, Inc. | 30,959 | $1.05M | 0.29% | +5,899+23.5% | Added |
| Millennium Management LLC | 32,144 | $1.09M | 0.00% | −366,123−91.9% | Reduced |
| Legato Capital Management LLC | 32,373 | $1.10M | 0.10% | +32,373 | New |
| MetLife Investment Management | 32,858 | $1.11M | 0.01% | +641+2.0% | Added |
| Hennion & Walsh Asset Management, Inc. | 33,868 | $1.15M | 0.04% | +398+1.2% | Added |
| Edgewood Management LLC | 35,000 | $1.18M | 0.01% | 00.0% | Unchanged |
| Martingale Asset Management L P | 35,814 | $1.21M | 0.03% | +35,814 | New |
| AQR Capital Management LLC | 36,410 | $1.23M | 0.00% | +8,484+30.4% | Added |
| Gsa Capital Partners LLP | 36,472 | $1.23M | 0.08% | +36,472 | New |
| Simplex Trading, LLC | 37,462 | $1.27M | 0.04% | +31,253+503.3% | Added |
| Virginia Retirement Systems Et Al | 39,061 | $1.32M | 0.01% | −2,300−5.6% | Reduced |
| Russell Investments Group, Ltd. | 39,710 | $1.34M | 0.00% | +15,031+60.9% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 42,071 | $1.39M | 0.00% | +2,616+6.6% | Added |
| Harbor Capital Advisors, Inc. | 43,005 | $1.46M | 0.12% | +5,777+15.5% | Added |
| Profund Advisors LLC | 45,794 | $1.55M | 0.06% | +5,944+14.9% | Added |
| Alps Advisors Inc | 47,701 | $1.61M | 0.01% | −180−0.4% | Reduced |
| Capital International Investors | 48,616 | $1.64M | 0.00% | −655,249−93.1% | Reduced |
| Alliancebernstein L.P. | 61,494 | $1.67M | 0.00% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 50,046 | $1.69M | 0.00% | −20,210−28.8% | Reduced |
| Deutsche Bank AG | 50,384 | $1.70M | 0.00% | −72,491−59.0% | Reduced |
| New York State Common Retirement Fund | 51,707 | $1.75M | 0.00% | 00.0% | Unchanged |
| Hudson Bay Capital Management LP | 51,830 | $1.75M | 0.01% | −48,170−48.2% | Reduced |
| Barclays PLC | 52,438 | $1.77M | 0.00% | −267,914−83.6% | Reduced |
| SG Americas Securities, LLC | 57,247 | $1.94M | 0.00% | +10,796+23.2% | Added |
| Tudor Investment Corp Et Al | 58,151 | $1.97M | 0.01% | −3,194−5.2% | Reduced |
| Vanguard Asset Management, Ltd | 58,648 | $1.98M | 0.00% | +58,648 | New |
| Headlands Technologies LLC | 59,257 | $2.00M | 0.23% | +6,518+12.4% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 60,679 | $2.05M | 0.00% | +119+0.2% | Added |
| SEI Investments Co | 63,550 | $2.15M | 0.00% | +49,198+342.8% | Added |
| Assenagon Asset Management S.A. | 67,153 | $2.27M | 0.00% | −43,287−39.2% | Reduced |
| California State Teachers Retirement System | 68,564 | $2.32M | 0.00% | +15,325+28.8% | Added |
| Rhumbline Advisers | 73,369 | $2.48M | 0.00% | −784−1.1% | Reduced |
| Woodline Partners LP | 74,423 | $2.52M | 0.01% | 00.0% | Unchanged |
| Trexquant Investment LP | 75,298 | $2.55M | 0.02% | −151,302−66.8% | Reduced |
| Knott David M Jr | 93,058 | $3.15M | 1.87% | +75,058+417.0% | Added |
| Tang Capital Management LLC | 100,000 | $3.38M | 0.17% | +100,000 | New |
| Rafferty Asset Management, LLC | 102,741 | $3.48M | 0.01% | −4,749−4.4% | Reduced |
| Essex Investment Management Co LLC | 103,177 | $3.49M | 0.55% | +103,177 | New |
| Swiss National Bank | 108,860 | $3.68M | 0.00% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 110,679 | $3.74M | 0.00% | +3,683+3.4% | Added |
| Pictet Asset Management Holding SA | 128,814 | $3.85M | 0.00% | −76,205−37.2% | Reduced |
| American Century Companies Inc | 120,253 | $4.07M | 0.00% | −31,233−20.6% | Reduced |
| Exome Asset Management LLC | 125,060 | $4.23M | 2.49% | −11,882−8.7% | Reduced |
| Capital Fund Management S.A. | 129,531 | $4.38M | 0.04% | +93,743+261.9% | Added |
| UBS Group AG | 132,540 | $4.48M | 0.00% | +5,875+4.6% | Added |
| JPMorgan Chase & Co | 151,558 | $4.49M | 0.00% | −100,219−39.8% | Reduced |
| ADAR1 Capital Management, LLC | 140,672 | $4.76M | 0.29% | −47,328−25.2% | Reduced |
| Edgestream Partners, L.P. | 143,731 | $4.86M | 0.16% | −24,267−14.4% | Reduced |
| Man Group plc | 144,297 | $4.88M | 0.01% | +144,297 | New |
| Invesco Ltd. | 151,430 | $5.12M | 0.00% | +8,850+6.2% | Added |
| XTX Topco Ltd | 160,880 | $5.44M | 0.09% | +114,841+249.4% | Added |
| Polygon Management Ltd. | 164,839 | $5.58M | 1.10% | +2,821+1.7% | Added |
| Group One Trading, L.P. | 173,279 | $5.86M | 0.19% | +6,665+4.0% | Added |
| Bank of New York Mellon Corp | 186,791 | $6.32M | 0.00% | −10,102−5.1% | Reduced |
| Qube Research & Technologies Ltd | 187,667 | $6.35M | 0.01% | −190,706−50.4% | Reduced |
| HRT Financial LP | 195,432 | $6.61M | 0.02% | +48,963+33.4% | Added |
| Eversept Partners, LP | 200,000 | $6.77M | 0.45% | +200,000 | New |
| Schonfeld Strategic Advisors LLC | 200,061 | $6.77M | 0.06% | +200,061 | New |
| Squarepoint Ops LLC | 208,888 | $7.07M | 0.02% | +87,125+71.6% | Added |
| Seven Fleet Capital Management LP | 209,547 | $7.09M | 2.23% | +177,809+560.2% | Added |
| Palo Alto Investors LP | 213,601 | $7.23M | 1.11% | +1,102+0.5% | Added |
| Panagora Asset Management Inc | 238,468 | $8.07M | 0.03% | +158,628+198.7% | Added |
| Arrowstreet Capital, Limited Partnership | 250,461 | $8.47M | 0.00% | +250,461 | New |
| Two Sigma Investments, LP | 251,636 | $8.51M | 0.01% | −48,520−16.2% | Reduced |
| Algert Global LLC | 268,435 | $9.08M | 0.14% | −145,783−35.2% | Reduced |
| Kennedy Capital Management, Inc. | 275,456 | $9.32M | 0.20% | +209,801+319.6% | Added |
| Price T Rowe Associates Inc | 298,783 | $10.1M | 0.00% | −339,103−53.2% | Reduced |
| BNP Paribas Arbitrage, SA | 327,457 | $11.1M | 0.01% | +84,787+34.9% | Added |
| Vanguard Fiduciary Trust Co | 382,021 | $12.9M | 0.00% | +382,021 | New |
| Parkman Healthcare Partners LLC | 403,525 | $13.7M | 1.42% | +303,921+305.1% | Added |
| ArrowMark Colorado Holdings LLC | 403,590 | $13.7M | 0.36% | −62,561−13.4% | Reduced |
| Legal & General Group Plc | 423,915 | $14.3M | 0.00% | +95,704+29.2% | Added |