Definium Therapeutics, Inc.
DFTX- 交易所
- Nasdaq
- 產業
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
近 90 天，Definium Therapeutics, Inc. 內部人申報 0 筆公開市場買進、6 筆賣出；2026 年第 2 季末有 362 家機構在 13F 申報持有，市值合計 $53.5 億；大師中只有杜肯家族辦公室持有。
2026 年第 1 季 13F 持有人
Definium Therapeutics, Inc. 在 2026/3/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 248
- 較 2025 年第 4 季 +42 家
- 持有股數
- 7,805 萬
- 較 2025 年第 4 季 +1,278 萬 (+19.6%)
- 總市值
- $14.7 億
- 較 2025 年第 4 季 +$6.01 億 (+68.7%)
- 新進機構
- 69
- 另有 82 家加碼
- 清倉機構
- 27
- 另有 53 家減碼
另有 3 家機構在 2025 年第 4 季持有、還沒有申報 2026 年第 1 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 DFTX 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 362 | $53.5 億 |
| 2026 年第 1 季 | 248 | $14.7 億 |
| 2025 年第 4 季 | 209 | $9.09 億 |
| 2025 年第 3 季 | 196 | $4.69 億 |
| 2025 年第 2 季 | 183 | $2.71 億 |
| 2025 年第 1 季 | 191 | $2.41 億 |
| 2024 年第 4 季 | 174 | $2.89 億 |
| 2024 年第 3 季 | 158 | $2.82 億 |
| 2024 年第 2 季 | 152 | $2.99 億 |
| 2024 年第 1 季 | 135 | $3.27 億 |
| 2023 年第 4 季 | 104 | $1,787 萬 |
| 2023 年第 3 季 | 93 | $1,213 萬 |
| 2023 年第 2 季 | 84 | $1,389 萬 |
| 2023 年第 1 季 | 89 | $1,255 萬 |
| 2022 年第 4 季 | 104 | $1,114 萬 |
| 2022 年第 3 季 | 101 | $2,053 萬 |
| 2022 年第 2 季 | 156 | $1,510 萬 |
| 2022 年第 1 季 | 159 | $5,362 萬 |
| 2021 年第 4 季 | 176 | $7,205 萬 |
| 2021 年第 3 季 | 175 | $1.05 億 |
| 2021 年第 2 季 | 156 | $1.31 億 |
| 2021 年第 1 季 | 8 | $93.2 萬 |
2026 年第 1 季持有機構
每家機構持有 Definium Therapeutics, Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 4 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Patient Square Capital LP | 331,000 | $625.6 萬 | 1.11% | +331,000 | 新進 |
| Sofinnova Investments, Inc. | 344,166 | $650.5 萬 | 0.33% | +344,166 | 新進 |
| Superstring Capital Management LP | 351,461 | $664.3 萬 | 4.75% | −73,741−17.3% | 減碼 |
| Tri Locum Partners LP | 369,588 | $698.5 萬 | 0.98% | +369,588 | 新進 |
| Integral Health Asset Management, LLC | 400,000 | $756.0 萬 | 0.40% | +50,000+14.3% | 加碼 |
| Deutsche Bank AG | 411,834 | $778.4 萬 | 0.00% | +13,565+3.4% | 加碼 |
| Qube Research & Technologies Ltd | 426,055 | $805.2 萬 | 0.01% | +426,055 | 新進 |
| Morgan Stanley | 438,573 | $828.9 萬 | 0.00% | +71,878+19.6% | 加碼 |
| UBS Group AG | 493,977 | $933.6 萬 | 0.00% | −189,825−27.8% | 減碼 |
| Blackstone Group Inc. | 508,668 | $961.4 萬 | 0.04% | −1,551,137−75.3% | 減碼 |
| Ensign Peak Advisors, Inc | 546,783 | $1,033 萬 | 0.02% | +284,783+108.7% | 加碼 |
| Vanguard Fiduciary Trust Co | 575,937 | $1,089 萬 | 0.00% | +575,937 | 新進 |
| Boxer Capital Management, LLC | 598,500 | $1,131 萬 | 1.49% | 00.0% | 不變 |
| Eventide Asset Management, LLC | 686,162 | $1,297 萬 | 0.21% | +686,162 | 新進 |
| Nuveen, LLC | 698,130 | $1,319 萬 | 0.00% | +421,676+152.5% | 加碼 |
| Woodline Partners LP | 752,792 | $1,423 萬 | 0.05% | +602,222+400.0% | 加碼 |
| Bank of New York Mellon Corp | 752,922 | $1,423 萬 | 0.00% | +454,262+152.1% | 加碼 |
| Northern Trust Corp | 798,987 | $1,510 萬 | 0.00% | +64,327+8.8% | 加碼 |
| OrbiMed Advisors LLC | 804,000 | $1,520 萬 | 0.35% | −422,700−34.5% | 減碼 |
| Charles Schwab Investment Management Inc | 808,715 | $1,528 萬 | 0.00% | +1,466+0.2% | 加碼 |
| Millennium Management LLC | 846,896 | $1,601 萬 | 0.01% | −536,279−38.8% | 減碼 |
| Vanguard Portfolio Management LLC | 872,665 | $1,649 萬 | 0.00% | +872,665 | 新進 |
| Siren, L.L.C. | 919,493 | $1,738 萬 | 0.48% | +119,493+14.9% | 加碼 |
| Ameriprise Financial Inc | 966,608 | $1,827 萬 | 0.00% | +462,367+91.7% | 加碼 |
| Catalio Capital Management, LP | 1,037,984 | $1,962 萬 | 4.10% | +1,037,984 | 新進 |
| AWM Investment Company, Inc. | 1,076,893 | $2,035 萬 | 2.25% | −313,769−22.6% | 減碼 |
| Holocene Advisors, LP | 1,091,967 | $2,064 萬 | 0.05% | +1,091,967 | 新進 |
| Vanguard Capital Management LLC | 1,096,978 | $2,073 萬 | 0.00% | +1,096,978 | 新進 |
| Adage Capital Partners GP, L.L.C. | 1,150,000 | $2,174 萬 | 0.03% | 00.0% | 不變 |
| Marshall Wace, LLP | 1,200,825 | $2,270 萬 | 0.02% | −1,774,877−59.6% | 減碼 |
| Two Sigma Investments, LP | 1,201,610 | $2,271 萬 | 0.02% | +776,403+182.6% | 加碼 |
| Balyasny Asset Management LLC | 1,274,221 | $2,408 萬 | 0.05% | −33,894−2.6% | 減碼 |
| Candriam Luxembourg S.C.A. | 1,293,629 | $2,445 萬 | 0.13% | +322,411+33.2% | 加碼 |
| Wellington Management Group LLP | 1,304,749 | $2,466 萬 | 0.00% | +84,082+6.9% | 加碼 |
| Citadel Advisors LLC | 1,333,442 | $2,520 萬 | 0.02% | +1,123,498+535.1% | 加碼 |
| ArrowMark Colorado Holdings LLC | 1,594,717 | $3,014 萬 | 0.80% | +1,594,717 | 新進 |
| Goldman Sachs Group Inc | 1,675,411 | $3,167 萬 | 0.00% | +750,079+81.1% | 加碼 |
| Trails Edge Capital Partners, LP | 1,738,110 | $3,285 萬 | 7.73% | −830,000−32.3% | 減碼 |
| FMR LLC | 1,809,610 | $3,420 萬 | 0.00% | +1,647,557+1,016.7% | 加碼 |
| Commodore Capital LP | 2,000,000 | $3,780 萬 | 2.19% | 00.0% | 不變 |
| Octagon Capital Advisors LP | 2,440,000 | $4,612 萬 | 5.10% | +210,000+9.4% | 加碼 |
| State Street Corp | 2,471,873 | $4,672 萬 | 0.00% | +103,807+4.4% | 加碼 |
| Geode Capital Management, LLC | 2,495,399 | $4,717 萬 | 0.00% | +162,461+7.0% | 加碼 |
| Deep Track Capital, LP | 3,000,000 | $5,670 萬 | 1.17% | +1,323,460+78.9% | 加碼 |
| Janus Henderson Group PLC | 3,556,041 | $6,723 萬 | 0.03% | +1,144,345+47.4% | 加碼 |
| Avoro Capital Advisors LLC | 5,000,000 | $9,450 萬 | 0.93% | 00.0% | 不變 |
| Driehaus Capital Management LLC | 5,911,889 | $1.12 億 | 0.82% | −625,313−9.6% | 減碼 |
| BlackRock, Inc. | 8,480,230 | $1.60 億 | 0.00% | +206,954+2.5% | 加碼 |
| Vestal Point Capital, LP | 0 | $0 | 0.00% | −637,000−100.0% | 清倉 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0 | $0 | 0.00% | −278,720−100.0% | 清倉 |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −65,281−100.0% | 清倉 |
| California State Teachers Retirement System | 0 | $0 | 0.00% | −58,383−100.0% | 清倉 |
| Scientech Research LLC | 0 | $0 | 0.00% | −31,699−100.0% | 清倉 |
| Dark Forest Capital Management LP | 0 | $0 | 0.00% | −30,661−100.0% | 清倉 |
| Mercer Global Advisors Inc | 0 | $0 | 0.00% | −20,392−100.0% | 清倉 |
| EntryPoint Capital, LLC | 0 | $0 | 0.00% | −20,219−100.0% | 清倉 |
| Rafferty Asset Management, LLC | 0 | $0 | 0.00% | −18,885−100.0% | 清倉 |
| Gotham Asset Management, LLC | 0 | $0 | 0.00% | −17,825−100.0% | 清倉 |
| Caxton Corp | 0 | $0 | 0.00% | −15,688−100.0% | 清倉 |
| Fore Capital, LLC | 0 | $0 | 0.00% | −15,000−100.0% | 清倉 |
| Wealth Enhancement Advisory Services, LLC | 0 | $0 | 0.00% | −13,718−100.0% | 清倉 |
| XTX Topco Ltd | 0 | $0 | 0.00% | −10,994−100.0% | 清倉 |
| Flagship Harbor Advisors, LLC | 0 | $0 | 0.00% | −8,721−100.0% | 清倉 |
| Amalgamated Bank | 0 | $0 | 0.00% | −2,957−100.0% | 清倉 |
| Quantbot Technologies LP | 0 | $0 | 0.00% | −1,649−100.0% | 清倉 |
| Atlantic Union Bankshares Corp | 0 | $0 | 0.00% | −500−100.0% | 清倉 |
| Daiwa Securities Group Inc. | 0 | $0 | 0.00% | −242−100.0% | 清倉 |
| Reflection Asset Management | 0 | $0 | 0.00% | −66−100.0% | 清倉 |
| Kohmann Bosshard Financial Services, LLC | 0 | $0 | 0.00% | −66−100.0% | 清倉 |
| Tradewinds Capital Management, LLC | 0 | $0 | 0.00% | −53−100.0% | 清倉 |
| CNB Bank | 0 | $0 | 0.00% | −10−100.0% | 清倉 |
| SageView Advisory Group, LLC | 0 | $0 | 0.00% | −6−100.0% | 清倉 |
| NBT Bank N A | 0 | $0 | 0.00% | −6−100.0% | 清倉 |
| Signaturefd, LLC | 0 | $0 | 0.00% | −2−100.0% | 清倉 |
| Navalign, LLC | 0 | $0 | 0.00% | −2−100.0% | 清倉 |
| Vanguard Group Inc | – | – | – | – | 本季未申報 |
| Global Retirement Partners, LLC | – | – | – | – | 本季未申報 |
| CIBC Private Wealth Group, LLC | – | – | – | – | 本季未申報 |