Tango Therapeutics, Inc.
TNGX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001819133
In the last 90 days, Tango Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $6.60B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Tango Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 170
- +31 vs. Q3 2025
- Shares held
- 172.4M
- +32.7M (+23.4%) vs. Q3 2025
- Total value
- $1.53B
- +$353.7M (+30.1%) vs. Q3 2025
- New holders
- 53
- 75 more added
- Sold out
- 22
- 27 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TNGX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 247 | $6.60B |
| Q1 2026 | 194 | $3.78B |
| Q4 2025 | 170 | $1.53B |
| Q3 2025 | 141 | $1.18B |
| Q2 2025 | 115 | $651.7M |
| Q1 2025 | 122 | $147.0M |
| Q4 2024 | 138 | $329.2M |
| Q3 2024 | 121 | $781.2M |
| Q2 2024 | 120 | $846.0M |
| Q1 2024 | 126 | $781.2M |
| Q4 2023 | 121 | $927.1M |
| Q3 2023 | 100 | $999.9M |
| Q2 2023 | 89 | $226.8M |
| Q1 2023 | 92 | $275.9M |
| Q4 2022 | 82 | $498.4M |
| Q3 2022 | 87 | $246.8M |
| Q2 2022 | 77 | $319.1M |
| Q1 2022 | 72 | $528.2M |
| Q4 2021 | 58 | $741.0M |
| Q3 2021 | 46 | $844.9M |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Tango Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Wells Fargo & Company | 121,186 | $1.07M | 0.00% | +66,181+120.3% | Added |
| Verition Fund Management LLC | 121,781 | $1.08M | 0.01% | +97,029+392.0% | Added |
| Rhumbline Advisers | 129,107 | $1.14M | 0.00% | +21,268+19.7% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 129,476 | $1.15M | 0.00% | +129,476 | New |
| ADAR1 Capital Management, LLC | 140,021 | $1.24M | 0.09% | +140,021 | New |
| Two Sigma Investments, LP | 144,432 | $1.28M | 0.00% | 00.0% | Unchanged |
| Citadel Advisors LLC | 151,880 | $1.35M | 0.00% | +151,880 | New |
| Squarepoint Ops LLC | 173,936 | $1.54M | 0.00% | +173,936 | New |
| Invesco Ltd. | 177,610 | $1.57M | 0.00% | −854,307−82.8% | Reduced |
| Fisher Asset Management, LLC | 187,693 | $1.66M | 0.00% | −22,659−10.8% | Reduced |
| TRV GP VI, LLC | 194,174 | $1.72M | 1.16% | 00.0% | Unchanged |
| Integral Health Asset Management, LLC | 200,000 | $1.77M | 0.09% | +200,000 | New |
| Seven Fleet Capital Management LP | 215,172 | $1.91M | 1.29% | +215,172 | New |
| Rafferty Asset Management, LLC | 226,601 | $2.01M | 0.01% | +81,285+55.9% | Added |
| Wellington Management Group LLP | 233,857 | $2.07M | 0.00% | −19,431−7.7% | Reduced |
| Congress Asset Management Co | 234,628 | $2.08M | 0.01% | +6,508+2.9% | Added |
| Voloridge Investment Management, LLC | 255,127 | $2.26M | 0.01% | −129,080−33.6% | Reduced |
| Acuta Capital Partners, LLC | 282,732 | $2.51M | 1.70% | +282,732 | New |
| Great Lakes Advisors, LLC | 294,303 | $2.61M | 0.02% | −129,548−30.6% | Reduced |
| Nuveen, LLC | 300,441 | $2.66M | 0.00% | −627,571−67.6% | Reduced |
| Qube Research & Technologies Ltd | 318,676 | $2.82M | 0.00% | +318,676 | New |
| Marshall Wace, LLP | 329,231 | $2.92M | 0.00% | −1,160,287−77.9% | Reduced |
| Bank of New York Mellon Corp | 343,840 | $3.05M | 0.00% | +151,492+78.8% | Added |
| Mass General Brigham, Inc | 354,192 | $3.14M | 0.39% | +354,192 | New |
| Barclays PLC | 368,187 | $3.26M | 0.00% | +2,507+0.7% | Added |
| Rock Springs Capital Management LP | 386,915 | $3.43M | 0.18% | +386,915 | New |
| T. Rowe Price Investment Management, Inc. | 446,213 | $3.95M | 0.00% | −3,080,146−87.3% | Reduced |
| Bank of America Corp | 478,062 | $4.24M | 0.00% | +322,615+207.5% | Added |
| Dimensional Fund Advisors LP | 487,076 | $4.32M | 0.00% | −185,659−27.6% | Reduced |
| Perceptive Advisors LLC | 513,035 | $4.55M | 0.08% | +513,035 | New |
| Sphera Funds Management Ltd. | 544,563 | $4.82M | 1.01% | +544,563 | New |
| Millennium Management LLC | 593,004 | $5.25M | 0.00% | −702,397−54.2% | Reduced |
| Bain Capital Life Sciences Investors, LLC | 653,493 | $5.79M | 0.44% | −2,058,515−75.9% | Reduced |
| Bessemer Group Inc | 708,398 | $6.28M | 0.01% | 00.0% | Unchanged |
| ArrowMark Colorado Holdings LLC | 708,385 | $6.28M | 0.14% | 00.0% | Unchanged |
| Candriam Luxembourg S.C.A. | 708,812 | $6.28M | 0.03% | 00.0% | Unchanged |
| Northern Trust Corp | 803,199 | $7.12M | 0.00% | +197,638+32.6% | Added |
| Charles Schwab Investment Management Inc | 840,992 | $7.45M | 0.00% | +182,700+27.8% | Added |
| Boothbay Fund Management, LLC | 957,282 | $8.48M | 0.22% | +957,282 | New |
| UBS Group AG | 990,458 | $8.78M | 0.00% | +829,980+517.2% | Added |
| Affinity Asset Advisors, LLC | 1,000,000 | $8.86M | 0.64% | +1,000,000 | New |
| D. E. Shaw & Co., Inc. | 1,025,553 | $9.09M | 0.01% | +595,174+138.3% | Added |
| Franklin Resources Inc | 1,398,057 | $12.4M | 0.00% | +471,153+50.8% | Added |
| Morgan Stanley | 1,421,794 | $12.6M | 0.00% | +1,170,001+464.7% | Added |
| RTW Investments, LP | 1,491,228 | $13.2M | 0.13% | +1,491,228 | New |
| Point72 Asset Management, L.P. | 1,974,035 | $17.5M | 0.03% | −945,415−32.4% | Reduced |
| Vivo Capital, LLC | 2,154,780 | $19.1M | 1.23% | +1,378,081+177.4% | Added |
| Deep Track Capital, LP | 2,454,562 | $21.7M | 0.50% | +1,000,000+68.7% | Added |
| Geode Capital Management, LLC | 2,553,656 | $22.6M | 0.00% | +670,879+35.6% | Added |
| Janus Henderson Group PLC | 2,644,237 | $23.5M | 0.01% | +341,963+14.9% | Added |
| Suvretta Capital Management, LLC | 2,662,227 | $23.6M | 0.59% | +2,662,227 | New |
| FMR LLC | 2,867,548 | $25.4M | 0.00% | +2,861,122+44,524.2% | Added |
| Deerfield Management Company, L.P. (Series C) | 2,906,946 | $25.8M | 0.33% | +2,906,946 | New |
| Nantahala Capital Management, LLC | 3,572,633 | $31.7M | 1.89% | +1,762,685+97.4% | Added |
| Caligan Partners LP | 3,729,895 | $33.0M | 3.03% | +3,729,895 | New |
| Bellevue Group AG | 3,927,670 | $34.8M | 0.66% | +3,927,670 | New |
| Logos Global Management LP | 4,200,000 | $37.2M | 2.48% | +3,250,000+342.1% | Added |
| Goldman Sachs Group Inc | 4,942,414 | $43.8M | 0.01% | +3,432,939+227.4% | Added |
| Balyasny Asset Management LLC | 5,278,580 | $46.8M | 0.09% | +1,806,373+52.0% | Added |
| State Street Corp | 6,218,567 | $55.1M | 0.00% | +2,853,362+84.8% | Added |
| Vanguard Group Inc | 6,750,977 | $59.8M | 0.00% | +1,698,974+33.6% | Added |
| Nextech Invest, Ltd. | 7,266,081 | $64.4M | 6.22% | +1,732,101+31.3% | Added |
| TRV GP IV, LLC | 7,874,574 | $69.8M | 27.35% | −5,989,401−43.2% | Reduced |
| Siren, L.L.C. | 8,165,374 | $72.3M | 2.16% | +2,282,186+38.8% | Added |
| BlackRock, Inc. | 8,540,797 | $75.7M | 0.00% | +2,893,878+51.2% | Added |
| Woodline Partners LP | 10,072,225 | $89.2M | 0.35% | +4,042,297+67.0% | Added |
| Adage Capital Partners GP, L.L.C. | 10,607,924 | $94.0M | 0.14% | +8,096,924+322.5% | Added |
| Boxer Capital Management, LLC | 10,876,219 | $96.4M | 21.09% | +1,104,734+11.3% | Added |
| TCG Crossover Management, LLC | 12,762,094 | $113.1M | 3.74% | +4,225,898+49.5% | Added |
| Farallon Capital Management, L.L.C. | 13,061,411 | $115.7M | 0.60% | +2,304,411+21.4% | Added |
| EcoR1 Capital, LLC | 0 | $0 | 0.00% | −10,630,736−100.0% | Sold out |
| Gilead Sciences, Inc. | 0 | $0 | 0.00% | −4,854,443−100.0% | Sold out |
| Paradigm Biocapital Advisors LP | 0 | $0 | 0.00% | −3,086,184−100.0% | Sold out |
| Ra Capital Management, L.P. | 0 | $0 | 0.00% | −2,000,000−100.0% | Sold out |
| Commodore Capital LP | 0 | $0 | 0.00% | −1,500,000−100.0% | Sold out |
| Avoro Capital Advisors LLC | 0 | $0 | 0.00% | −545,000−100.0% | Sold out |
| StemPoint Capital LP | 0 | $0 | 0.00% | −245,378−100.0% | Sold out |
| Readystate Asset Management LP | 0 | $0 | 0.00% | −245,109−100.0% | Sold out |
| Fred Alger Management, LLC | 0 | $0 | 0.00% | −230,316−100.0% | Sold out |
| Susquehanna Fundamental Investments, LLC | 0 | $0 | 0.00% | −157,233−100.0% | Sold out |
| Blue Owl Capital Holdings LP | 0 | $0 | 0.00% | −119,416−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −94,100−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −55,300−100.0% | Sold out |
| Quadrature Capital Ltd | 0 | $0 | 0.00% | −36,189−100.0% | Sold out |
| Harvest Investment Services, LLC | 0 | $0 | 0.00% | −31,840−100.0% | Sold out |
| Clear Harbor Asset Management, LLC | 0 | $0 | 0.00% | −30,300−100.0% | Sold out |
| J. Goldman & Co LP | 0 | $0 | 0.00% | −29,036−100.0% | Sold out |
| Simplicity Wealth,LLC | 0 | $0 | 0.00% | −26,961−100.0% | Sold out |
| TD Asset Management Inc | 0 | $0 | 0.00% | −18,072−100.0% | Sold out |
| DRW Securities, LLC | 0 | $0 | 0.00% | −14,778−100.0% | Sold out |
| Belvedere Trading LLC | 0 | $0 | 0.00% | −10,845−100.0% | Sold out |
| US Bancorp | 0 | $0 | 0.00% | −53−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | – | – | – | – | Not filed |
| Corton Capital Inc. | – | – | – | – | Not filed |