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Sionna Therapeutics, Inc.

SION
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0002036042

In the last 90 days, Sionna Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 146 institutions reported holding it in 13F filings for Q2 2026, worth $2.11B in total; Viking Global Investors is the only superinvestor holding it.

Q4 2025 vs. Q3 2025

How the institutions holding Sionna Therapeutics, Inc. changed between Q3 2025 and Q4 2025.

All holders in Q4 2025All holders in Q3 2025

13F holders of SION: Q3 2025 compared with Q4 2025
MeasureQ3 2025Q4 2025Change
Holders78101+23
Shares42.8M44.0M+1.11M (+2.6%)
Value$1.26B$1.81B+$548.2M (+43.5%)

New holders (30)

Institutions that held Sionna Therapeutics, Inc. at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to SION in Q4 2025
InstitutionSharesValue% of portfolio
Eventide Asset Management, LLC639,045$26.3M0.41%
Kalehua Capital Management LLC197,072$8.11M8.02%
Superstring Capital Management LP180,593$7.43M3.98%
Artia Global Partners LP119,741$4.93M0.79%
Invesco Ltd.111,162$4.57M0.00%
Ensign Peak Advisors, Inc79,862$3.29M0.01%
Seven Grand Managers, LLC50,000$2.06M0.16%
Alps Advisors Inc36,648$1.51M0.01%
Rafferty Asset Management, LLC24,690$1.02M0.00%
Alliancebernstein L.P.15,620$642.6K0.00%
SG Americas Securities, LLC10,691$440.0K0.00%
Profund Advisors LLC9,213$379.0K0.01%
Kennedy Capital Management, Inc.6,752$277.8K0.01%
Two Sigma Investments, LP6,400$263.3K0.00%
American Century Companies Inc6,180$254.2K0.00%
Dark Forest Capital Management LP5,991$246.5K0.01%
D. E. Shaw & Co., Inc.5,742$236.2K0.00%
XTX Topco Ltd4,926$202.7K0.01%
ProShare Advisors LLC4,903$201.7K0.00%
Los Angeles Capital Management LLC5,189$197.2K0.00%
CIBC Private Wealth Group, LLC4,500$185.1K0.00%
AlphaCentric Advisors LLC2,720$111.9K0.11%
Cygnus Capital Advisors, LLC2,400$99.0K0.07%
Mirae Asset Global Investments Co., Ltd.2,169$89.2K0.00%
Balyasny Asset Management LLC1,406$57.8K0.00%
GF Fund Management Co. Ltd.876$36.0K0.00%
Farther Finance Advisors, LLC190$7.82K0.00%
Daiwa Securities Group Inc.149$6.00K0.00%
Rockefeller Capital Management L.P.48$1.98K0.00%
Rothschild Investment LLC1$410.00%

Sold out (7)

Institutions that held Sionna Therapeutics, Inc. at the end of Q3 2025 and filed for Q4 2025 without it.

Institutions that sold out of SION in Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Braidwell LP314,013$9.24M
Holocene Advisors, LP50,000$1.47M
Marshall Wace, LLP30,103$885.3K
Renaissance Technologies LLC14,600$429.4K
Jain Global LLC8,513$250.4K
Federated Hermes, Inc.113$3.32K
SRS Capital Advisors, Inc.92$2.71K