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Regulus Therapeutics Inc.

RGLSDelisted Jun 25, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001505512

Regulus Therapeutics Inc. was delisted on Jun 25, 2025; its insiders filed their last Form 4 on Jun 27, 2025; 75 institutions reported holding it in 13F filings for Q1 2025, worth $107.0M in total; no superinvestor held it.

13F holders, Q2 2024

Institutional positions in Regulus Therapeutics Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
63
+18 vs. Q1 2024
Shares held
61.3M
+9.24M (+17.7%) vs. Q1 2024
Total value
$109.5M
−$37.8M (−25.7%) vs. Q1 2024
New holders
28
13 more added
Sold out
10
14 more reduced

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RGLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 63 institutions
Q1 2021: 44 institutionsQ2 2021: 45 institutionsQ3 2021: 42 institutionsQ4 2021: 38 institutionsQ1 2022: 37 institutionsQ2 2022: 28 institutionsQ3 2022: 25 institutionsQ4 2022: 28 institutionsQ1 2023: 27 institutionsQ2 2023: 26 institutionsQ3 2023: 25 institutionsQ4 2023: 26 institutionsQ1 2024: 45 institutionsQ2 2024: 63 institutionsQ3 2024: 70 institutionsQ4 2024: 69 institutionsQ1 2025: 75 institutionsQ2 2025: 1 institutionQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ2 2024: $109.5M
Q1 2021: $42.6MQ2 2021: $18.7MQ3 2021: $15.9MQ4 2021: $9.54MQ1 2022: $18.1MQ2 2022: $12.6MQ3 2022: $13.8MQ4 2022: $11.1MQ1 2023: $6.82MQ2 2023: $15.0MQ3 2023: $15.0MQ4 2023: $14.2MQ1 2024: $147.3MQ2 2024: $109.5MQ3 2024: $89.1MQ4 2024: $84.5MQ1 2025: $107.0MQ2 2025: $760Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding RGLS and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20251$760
Q1 202575$107.0M
Q4 202469$84.5M
Q3 202470$89.1M
Q2 202463$109.5M
Q1 202445$147.3M
Q4 202326$14.2M
Q3 202325$15.0M
Q2 202326$15.0M
Q1 202327$6.82M
Q4 202228$11.1M
Q3 202225$13.8M
Q2 202228$12.6M
Q1 202237$18.1M
Q4 202138$9.54M
Q3 202142$15.9M
Q2 202145$18.7M
Q1 202144$42.6M

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Regulus Therapeutics Inc.; share changes are against Q1 2024.

Institutions holding RGLS in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Federated Hermes, Inc.12,852,654$22.9M0.05%00.0%Unchanged
NEA Management Company, LLC6,467,802$11.6M0.87%00.0%Unchanged
Ra Capital Management, L.P.6,250,000$11.2M0.15%00.0%Unchanged
Vivo Capital, LLC5,000,000$8.93M0.82%00.0%Unchanged
Octagon Capital Advisors LP4,263,701$7.61M1.26%+4,263,701New
Vanguard Group Inc4,050,863$7.23M0.00%+3,310,648+447.3%Added
BlackRock Inc.3,968,857$7.08M0.00%+3,900,826+5,733.9%Added
Deep Track Capital, LP3,262,564$5.82M0.17%−4,002−0.1%Reduced
FMR LLC2,022,600$3.61M0.00%−900,000−30.8%Reduced
Adage Capital Partners GP, L.L.C.2,000,000$3.57M0.01%−1,679,854−45.7%Reduced
Opaleye Management Inc.1,475,000$2.63M0.60%+1,304,692+766.1%Added
Geode Capital Management, LLC1,333,509$2.38M0.00%+1,172,919+730.4%Added
Millennium Management LLC1,215,581$2.17M0.00%−659,645−35.2%Reduced
State Street Corp967,502$1.73M0.00%+925,783+2,219.1%Added
Woodline Partners LP947,685$1.69M0.02%+947,685New
Alyeska Investment Group, L.P.937,500$1.67M0.01%00.0%Unchanged
DAFNA Capital Management LLC895,200$1.60M0.38%−175,348−16.4%Reduced
CVI Holdings, LLC401,012$715.8K0.62%−1,005,238−71.5%Reduced
Victory Capital Management Inc361,386$645.1K0.00%−6,760−1.8%Reduced
ExodusPoint Capital Management, LP329,639$588.0K0.01%+329,639New
Hudson Bay Capital Management LP249,940$446.1K0.00%−375,060−60.0%Reduced
Bank of New York Mellon Corp197,193$352.0K0.00%+197,193New
Monashee Investment Management LLC197,049$351.7K0.05%−427,951−68.5%Reduced
Sarissa Capital Management LP185,183$330.6K0.06%00.0%Unchanged
Charles Schwab Investment Management Inc178,879$319.3K0.00%+178,879New
Northern Trust Corp172,750$308.4K0.00%+154,772+860.9%Added
Goldman Sachs Group Inc138,465$247.2K0.00%−88,954−39.1%Reduced
Renaissance Technologies LLC118,100$210.8K0.00%+42,600+56.4%Added
Nuveen Asset Management, LLC85,602$152.8K0.00%+85,602New
Rhumbline Advisers76,472$136.5K0.00%+76,472New
Morgan Stanley62,970$112.4K0.00%+35,151+126.4%Added
PEAK6 Investments LLC60,000$107.1K0.00%+60,000New
Alpine Global Management, LLC59,004$105.3K0.02%+59,004New
New York State Common Retirement Fund49,400$88.2K0.00%+49,400New
LPL Financial LLC46,980$83.9K0.00%−66,500−58.6%Reduced
Two Sigma Securities, LLC38,451$68.6K0.00%+38,451New
Two Sigma Investments, LP35,299$63.0K0.00%+35,299New
Corebridge Financial, Inc.33,974$61.0K0.00%+33,974New
Bank of America Corp33,056$59.0K0.00%+33,056New
Invesco Ltd.29,061$51.9K0.00%+29,061New
JPMorgan Chase & Co26,913$48.0K0.00%+7,171+36.3%Added
Alliancebernstein L.P.26,880$48.0K0.00%+26,880New
Wells Fargo & Company25,848$46.1K0.00%+25,706+18,102.8%Added
Voya Investment Management LLC23,074$41.2K0.00%+23,074New
Barclays PLC21,928$39.1K0.00%+21,928New
UBS Group AG19,217$34.3K0.00%+18,915+6,263.2%Added
Commonwealth Equity Services, LLC18,000$32.0K0.00%00.0%Unchanged
MetLife Investment Management16,779$30.0K0.00%+16,779New
Citigroup Inc14,165$25.3K0.00%−20.0%Reduced
Prelude Capital Management, LLC14,100$25.2K0.00%−118,370−89.4%Reduced
Grimes & Company, Inc.10,975$19.6K0.00%+711+6.9%Added
Tyche Wealth Partners LLC10,395$18.6K0.00%+10,395New
Ameritas Investment Partners, Inc.6,187$11.0K0.00%+6,187New
Royal Bank of Canada5,948$11.0K0.00%+5,897+11,562.7%Added
Legal & General Group Plc5,956$10.6K0.00%+5,956New
California State Teachers Retirement System4,576$8.17K0.00%+4,576New
Simplex Trading, LLC3,622$6.00K0.00%−71,828−95.2%Reduced
Amalgamated Bank2,185$4.00K0.00%+2,185New
Advisor Group Holdings, Inc.800$1.43K0.00%+800New
Community Bank, N.A.690$1.23K0.00%00.0%Unchanged
Parallel Advisors, LLC10$180.00%+10New
Price T Rowe Associates Inc20,393$00.00%+20,393New
Lazard Asset Management LLC122$00.00%+122New
Soleus Capital Management, L.P.0$00.00%−1,562,500−100.0%Sold out
Polar Asset Management Partners Inc.0$00.00%−536,400−100.0%Sold out
Exome Asset Management LLC0$00.00%−402,504−100.0%Sold out
HRT Financial LP0$00.00%−62,797−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−24,253−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−22,528−100.0%Sold out
CTC Alternative Strategies, Ltd.0$00.00%−18,500−100.0%Sold out
Group One Trading, L.P.0$00.00%−8,607−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−3,212−100.0%Sold out
Macquarie Group Ltd0$00.00%−865−100.0%Sold out