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Regulus Therapeutics Inc.

RGLSDelisted Jun 25, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001505512

Regulus Therapeutics Inc. was delisted on Jun 25, 2025; its insiders filed their last Form 4 on Jun 27, 2025; 75 institutions reported holding it in 13F filings for Q1 2025, worth $107.0M in total; no superinvestor held it.

13F holders, Q1 2024

Institutional positions in Regulus Therapeutics Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
45
+19 vs. Q4 2023
Shares held
52.1M
+41.0M (+368.7%) vs. Q4 2023
Total value
$147.3M
+$133.1M (+935.3%) vs. Q4 2023
New holders
22
14 more added
Sold out
3
4 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RGLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 45 institutions
Q1 2021: 44 institutionsQ2 2021: 45 institutionsQ3 2021: 42 institutionsQ4 2021: 38 institutionsQ1 2022: 37 institutionsQ2 2022: 28 institutionsQ3 2022: 25 institutionsQ4 2022: 28 institutionsQ1 2023: 27 institutionsQ2 2023: 26 institutionsQ3 2023: 25 institutionsQ4 2023: 26 institutionsQ1 2024: 45 institutionsQ2 2024: 63 institutionsQ3 2024: 70 institutionsQ4 2024: 69 institutionsQ1 2025: 75 institutionsQ2 2025: 1 institutionQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ1 2024: $147.3M
Q1 2021: $42.6MQ2 2021: $18.7MQ3 2021: $15.9MQ4 2021: $9.54MQ1 2022: $18.1MQ2 2022: $12.6MQ3 2022: $13.8MQ4 2022: $11.1MQ1 2023: $6.82MQ2 2023: $15.0MQ3 2023: $15.0MQ4 2023: $14.2MQ1 2024: $147.3MQ2 2024: $109.5MQ3 2024: $89.1MQ4 2024: $84.5MQ1 2025: $107.0MQ2 2025: $760Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding RGLS and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20251$760
Q1 202575$107.0M
Q4 202469$84.5M
Q3 202470$89.1M
Q2 202463$109.5M
Q1 202445$147.3M
Q4 202326$14.2M
Q3 202325$15.0M
Q2 202326$15.0M
Q1 202327$6.82M
Q4 202228$11.1M
Q3 202225$13.8M
Q2 202228$12.6M
Q1 202237$18.1M
Q4 202138$9.54M
Q3 202142$15.9M
Q2 202145$18.7M
Q1 202144$42.6M

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Regulus Therapeutics Inc.; share changes are against Q4 2023.

Institutions holding RGLS in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Federated Hermes, Inc.12,852,654$34.4M0.08%+8,977,076+231.6%Added
NEA Management Company, LLC6,467,802$18.6M1.16%+4,522,223+232.4%Added
Ra Capital Management, L.P.6,250,000$18.0M0.23%+6,250,000New
Vivo Capital, LLC5,000,000$14.4M1.13%+5,000,000New
Adage Capital Partners GP, L.L.C.3,679,854$10.6M0.02%+3,679,854New
Deep Track Capital, LP3,266,566$9.41M0.27%+3,266,566New
FMR LLC2,922,600$8.42M0.00%00.0%Unchanged
Millennium Management LLC1,875,226$5.40M0.00%+1,875,226New
Soleus Capital Management, L.P.1,562,500$4.50M0.40%+1,562,500New
CVI Holdings, LLC1,406,250$4.05M3.81%+1,406,250New
DAFNA Capital Management LLC1,070,548$3.08M0.70%−40,501−3.6%Reduced
Alyeska Investment Group, L.P.937,500$2.68M0.02%+937,500New
Vanguard Group Inc740,215$2.13M0.00%+453,784+158.4%Added
Monashee Investment Management LLC625,000$1.80M0.21%+625,000New
Hudson Bay Capital Management LP625,000$1.68M0.01%+625,000New
Polar Asset Management Partners Inc.536,400$1.54M0.04%+536,400New
Exome Asset Management LLC402,504$1.16M0.99%+224,100+125.6%Added
Victory Capital Management Inc368,146$1.06M0.00%+96,410+35.5%Added
Goldman Sachs Group Inc227,419$655.0K0.00%+227,419New
Sarissa Capital Management LP185,183$533.3K0.09%00.0%Unchanged
Opaleye Management Inc.170,308$490.5K0.11%+170,308New
Geode Capital Management, LLC160,590$462.6K0.00%+38,069+31.1%Added
Prelude Capital Management, LLC132,470$381.5K0.03%+92,210+229.0%Added
LPL Financial LLC113,480$326.8K0.00%+113,480New
Renaissance Technologies LLC75,500$217.0K0.00%+20,900+38.3%Added
Simplex Trading, LLC75,450$217.0K0.01%+75,450New
BlackRock Inc.68,031$195.9K0.00%+67,458+11,772.8%Added
HRT Financial LP62,797$180.0K0.00%+62,797New
State Street Corp41,719$120.2K0.00%00.0%Unchanged
Morgan Stanley27,819$80.1K0.00%+27,819New
Balyasny Asset Management LLC24,253$69.8K0.00%+24,253New
Susquehanna International Group, LLP22,528$64.9K0.00%+22,528New
JPMorgan Chase & Co19,742$56.9K0.00%+19,713+67,975.9%Added
CTC Alternative Strategies, Ltd.18,500$53.3K0.03%+18,500New
Commonwealth Equity Services, LLC18,000$52.0K0.00%+500+2.9%Added
Northern Trust Corp17,978$51.8K0.00%00.0%Unchanged
Citigroup Inc14,167$40.8K0.00%+12,044+567.3%Added
Grimes & Company, Inc.10,264$29.6K0.00%−156−1.5%Reduced
Group One Trading, L.P.8,607$24.8K0.00%+8,607New
Tower Research Capital LLC (TRC)3,212$9.25K0.00%+3,195+18,794.1%Added
Community Bank, N.A.690$1.98K0.00%00.0%Unchanged
UBS Group AG302$8700.00%−42−12.2%Reduced
Wells Fargo & Company142$4090.00%+2+1.4%Added
Macquarie Group Ltd865$20.00%+865New
Royal Bank of Canada51$00.00%−29−36.3%Reduced
Citadel Advisors LLC0$00.00%−28,461−100.0%Sold out
Bank of America Corp0$00.00%−11−100.0%Sold out
Acadian Asset Management LLC0$00.00%−466−100.0%Sold out