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Regulus Therapeutics Inc.

RGLSDelisted Jun 25, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001505512

Regulus Therapeutics Inc. was delisted on Jun 25, 2025; its insiders filed their last Form 4 on Jun 27, 2025; 75 institutions reported holding it in 13F filings for Q1 2025, worth $107.0M in total; no superinvestor held it.

13F holders, Q1 2022

Institutional positions in Regulus Therapeutics Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
37
0 vs. Q4 2021
Shares held
60.7M
+33.2M (+121.1%) vs. Q4 2021
Total value
$18.1M
+$9.40M (+108.3%) vs. Q4 2021
New holders
3
15 more added
Sold out
3
5 more reduced

1 institution that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting RGLS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 37 institutions
Q1 2021: 44 institutionsQ2 2021: 45 institutionsQ3 2021: 42 institutionsQ4 2021: 38 institutionsQ1 2022: 37 institutionsQ2 2022: 28 institutionsQ3 2022: 25 institutionsQ4 2022: 28 institutionsQ1 2023: 27 institutionsQ2 2023: 26 institutionsQ3 2023: 25 institutionsQ4 2023: 26 institutionsQ1 2024: 45 institutionsQ2 2024: 63 institutionsQ3 2024: 70 institutionsQ4 2024: 69 institutionsQ1 2025: 75 institutionsQ2 2025: 1 institutionQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ1 2022: $18.1M
Q1 2021: $42.6MQ2 2021: $18.7MQ3 2021: $15.9MQ4 2021: $9.54MQ1 2022: $18.1MQ2 2022: $12.6MQ3 2022: $13.8MQ4 2022: $11.1MQ1 2023: $6.82MQ2 2023: $15.0MQ3 2023: $15.0MQ4 2023: $14.2MQ1 2024: $147.3MQ2 2024: $109.5MQ3 2024: $89.1MQ4 2024: $84.5MQ1 2025: $107.0MQ2 2025: $760Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding RGLS and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20251$760
Q1 202575$107.0M
Q4 202469$84.5M
Q3 202470$89.1M
Q2 202463$109.5M
Q1 202445$147.3M
Q4 202326$14.2M
Q3 202325$15.0M
Q2 202326$15.0M
Q1 202327$6.82M
Q4 202228$11.1M
Q3 202225$13.8M
Q2 202228$12.6M
Q1 202237$18.1M
Q4 202138$9.54M
Q3 202142$15.9M
Q2 202145$18.7M
Q1 202144$42.6M

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Regulus Therapeutics Inc.; share changes are against Q4 2021.

Institutions holding RGLS in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Federated Hermes, Inc.29,048,265$8.66M0.02%+29,048,265New
NEA Management Company, LLC14,451,147$4.31M0.14%+8,000,091+124.0%Added
DAFNA Capital Management LLC5,555,555$1.66M0.43%00.0%Unchanged
Vanguard Group Inc3,678,334$1.10M0.00%+648,121+21.4%Added
Victory Capital Management Inc2,233,031$664.0K0.00%−5130.0%Reduced
Sarissa Capital Management LP1,851,851$552.0K0.05%00.0%Unchanged
Ikarian Capital, LLC1,289,130$384.0K0.12%+60,714+4.9%Added
Geode Capital Management, LLC649,070$193.0K0.00%+59,874+10.2%Added
Price T Rowe Associates Inc184,600$55.0K0.00%00.0%Unchanged
State Street Corp176,494$53.0K0.00%00.0%Unchanged
Two Sigma Advisers, LP170,500$51.0K0.00%+19,200+12.7%Added
Northern Trust Corp168,172$50.0K0.00%+50,518+42.9%Added
Renaissance Technologies LLC133,400$40.0K0.00%+111,100+498.2%Added
Commonwealth Equity Services, LLC131,000$39.0K0.00%+12,000+10.1%Added
Boothbay Fund Management, LLC124,056$37.0K0.00%00.0%Unchanged
Two Sigma Investments, LP114,440$34.0K0.00%+59,134+106.9%Added
Grimes & Company, Inc.88,203$26.0K0.00%+27,127+44.4%Added
Group One Trading, L.P.81,872$24.0K0.00%−6,305−7.2%Reduced
Jane Street Group, LLC73,644$22.0K0.00%+49,218+201.5%Added
WealthTrust Axiom LLC68,000$20.0K0.01%00.0%Unchanged
Susquehanna International Group, LLP65,825$20.0K0.00%+65,825New
UBS Group AG61,710$18.0K0.00%+37,757+157.6%Added
Lido Advisors, LLC54,500$16.0K0.00%00.0%Unchanged
Millennium Management LLC48,886$15.0K0.00%+48,886New
GYL Financial Synergies, LLC34,000$10.0K0.00%−7,000−17.1%Reduced
Tower Research Capital LLC (TRC)28,441$8.00K0.00%+21,600+315.7%Added
All Terrain Financial Advisors, LLC15,000$4.00K0.00%00.0%Unchanged
McGuire Investment Group, LLC15,000$4.00K0.00%00.0%Unchanged
Dowling & Yahnke LLC12,000$4.00K0.00%00.0%Unchanged
Creative Planning12,000$4.00K0.00%−2,200−15.5%Reduced
Blair William & Co11,200$3.00K0.00%+500+4.7%Added
Wells Fargo & Company7,217$2.00K0.00%+369+5.4%Added
Royal Bank of Canada6,407$2.00K0.00%−656−9.3%Reduced
BlackRock Inc.6,927$2.00K0.00%00.0%Unchanged
Endurance Wealth Management, Inc.6,750$2.00K0.00%00.0%Unchanged
Community Bank, N.A.6,900$2.00K0.00%00.0%Unchanged
FMR LLC3$00.00%00.0%Unchanged
Empery Asset Management, LP0$00.00%−5,074,251−100.0%Sold out
Morgan Stanley0$00.00%−6,000−100.0%Sold out
Simplex Trading, LLC0$00.00%−1,049−100.0%Sold out
Asymmetry Capital Management, L.P.––––Not filed