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Prothena Corp Public Ltd Co

PRTA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001559053

In the last 90 days, Prothena Corp Public Ltd Co insiders filed 5 open-market purchases and 2 sales; 187 institutions reported holding it in 13F filings for Q2 2026, worth $462.7M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Prothena Corp Public Ltd Co as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
182
0 vs. Q3 2025
Shares held
47.3M
+4.86M (+11.5%) vs. Q3 2025
Total value
$451.6M
+$37.8M (+9.1%) vs. Q3 2025
New holders
25
62 more added
Sold out
25
57 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRTA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 182 institutions
Q1 2021: 146 institutionsQ2 2021: 156 institutionsQ3 2021: 192 institutionsQ4 2021: 196 institutionsQ1 2022: 174 institutionsQ2 2022: 167 institutionsQ3 2022: 183 institutionsQ4 2022: 201 institutionsQ1 2023: 192 institutionsQ2 2023: 196 institutionsQ3 2023: 187 institutionsQ4 2023: 187 institutionsQ1 2024: 169 institutionsQ2 2024: 160 institutionsQ3 2024: 164 institutionsQ4 2024: 171 institutionsQ1 2025: 161 institutionsQ2 2025: 189 institutionsQ3 2025: 187 institutionsQ4 2025: 182 institutionsQ1 2026: 186 institutionsQ2 2026: 187 institutions
Value heldQ4 2025: $451.6M
Q1 2021: $1.00BQ2 2021: $2.08BQ3 2021: $2.92BQ4 2021: $2.12BQ1 2022: $1.61BQ2 2022: $1.21BQ3 2022: $2.69BQ4 2022: $2.98BQ1 2023: $2.51BQ2 2023: $3.54BQ3 2023: $2.56BQ4 2023: $1.95BQ1 2024: $1.33BQ2 2024: $1.05BQ3 2024: $855.8MQ4 2024: $741.3MQ1 2025: $647.2MQ2 2025: $253.6MQ3 2025: $415.8MQ4 2025: $451.6MQ1 2026: $459.5MQ2 2026: $462.7M
Institutions holding PRTA and their total value by quarter
QuarterHoldersValue
Q2 2026187$462.7M
Q1 2026186$459.5M
Q4 2025182$451.6M
Q3 2025187$415.8M
Q2 2025189$253.6M
Q1 2025161$647.2M
Q4 2024171$741.3M
Q3 2024164$855.8M
Q2 2024160$1.05B
Q1 2024169$1.33B
Q4 2023187$1.95B
Q3 2023187$2.56B
Q2 2023196$3.54B
Q1 2023192$2.51B
Q4 2022201$2.98B
Q3 2022183$2.69B
Q2 2022167$1.21B
Q1 2022174$1.61B
Q4 2021196$2.12B
Q3 2021192$2.92B
Q2 2021156$2.08B
Q1 2021146$1.00B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Prothena Corp Public Ltd Co; share changes are against Q3 2025.

Institutions holding PRTA in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
STRS Ohio17,600$168.1K0.00%−11,200−38.9%Reduced
Atom Investors LP17,026$162.6K0.01%−4,289−20.1%Reduced
Entropy Technologies, LP16,900$161.4K0.01%+16,900New
Raymond James Financial Inc16,483$157.4K0.00%−5,549−25.2%Reduced
Susquehanna International Group, LLP15,975$152.6K0.00%−141,472−89.9%Reduced
Chicago Partners Investment Group LLC15,222$152.2K0.00%+381+2.6%Added
Jones Financial Companies LLLP15,900$151.8K0.00%+1,900+13.6%Added
State Board of Administration of Florida Retirement System15,386$146.9K0.00%00.0%Unchanged
Manufacturers Life Insurance Company, The13,695$130.8K0.00%−172−1.2%Reduced
Great Lakes Advisors, LLC13,189$126.0K0.00%−95−0.7%Reduced
Cary Street Partners Financial LLC12,500$119.4K0.00%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey12,453$118.9K0.00%−11−0.1%Reduced
Citigroup Inc12,318$117.6K0.00%+8,726+242.9%Added
Skopos Labs, Inc.12,047$114.2K0.01%+934+8.4%Added
DRW Securities, LLC11,955$114.2K0.01%+11,955New
PDT Partners, LLC11,334$108.2K0.01%+11,334New
Inscription Capital, LLC10,652$101.7K0.01%+172+1.6%Added
ProShare Advisors LLC10,425$99.6K0.00%+10,425New
CWM, LLC10,095$96.0K0.00%−151−1.5%Reduced
Fox Run Management, L.L.C.10,045$95.9K0.01%−34,287−77.3%Reduced
New York State Common Retirement Fund8,979$85.7K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.8,772$83.8K0.01%−664−7.0%Reduced
Canada Pension Plan Investment Board7,100$67.8K0.00%+7,100New
Public Employees Retirement Association of Colorado6,552$63.0K0.00%00.0%Unchanged
Pinnacle Wealth Planning Services, Inc.5,668$54.1K0.01%+5,668New
Brown Brothers Harriman & Co5,000$47.8K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.4,590$43.8K0.00%+185+4.2%Added
Royal Bank of Canada4,427$42.0K0.00%−5,904−57.1%Reduced
Legal & General Group Plc4,044$38.6K0.00%+445+12.4%Added
Signaturefd, LLC3,609$34.5K0.00%−61−1.7%Reduced
Ameritas Investment Partners, Inc.3,428$32.7K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)2,826$27.0K0.00%+1,541+119.9%Added
California State Teachers Retirement System2,710$25.9K0.00%+295+12.2%Added
Mirae Asset Global Investments Co., Ltd.2,616$25.0K0.00%+535+25.7%Added
Farther Finance Advisors, LLC2,434$23.2K0.00%00.0%Unchanged
Sterling Capital Management LLC2,327$22.2K0.00%−220−8.6%Reduced
Versant Capital Management, Inc2,044$19.5K0.00%00.0%Unchanged
Simplex Trading, LLC1,927$18.4K0.00%−40,117−95.4%Reduced
Flagship Wealth Advisors, LLC1,500$14.3K0.00%00.0%Unchanged
Amalgamated Bank1,383$13.0K0.00%−57−4.0%Reduced
Quadrant Capital Group LLC1,260$12.0K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.1,057$10.1K0.00%−98−8.5%Reduced
Federation des caisses Desjardins du Quebec1,000$9.55K0.00%+1,000New
HighMark Wealth Management LLC900$8.60K0.00%−1,108−55.2%Reduced
Allworth Financial LP885$8.45K0.00%+20+2.3%Added
Torren Management, LLC884$8.44K0.00%+884New
HM Payson & Co600$5.73K0.00%00.0%Unchanged
GAMMA Investing LLC510$4.87K0.00%+124+32.1%Added
US Bancorp359$3.43K0.00%+45+14.3%Added
Essential Partners LLC333$3.18K0.00%00.0%Unchanged
Optiver Holding B.V.296$2.83K0.00%−56−15.9%Reduced
Advisor Group Holdings, Inc.237$2.26K0.00%−6−2.5%Reduced
Daiwa Securities Group Inc.195$2.00K0.00%00.0%Unchanged
Evelyn Partners Investment Management LLP199$1.90K0.00%00.0%Unchanged
Basecamp Wealth Advisors LLC197$1.88K0.00%+197New
Asset Dedication, LLC184$1.76K0.00%00.0%Unchanged
Parallel Advisors, LLC179$1.71K0.00%00.0%Unchanged
Sittner & Nelson, LLC185$1.65K0.00%+30+19.4%Added
Johnson Financial Group, Inc.151$1.44K0.00%00.0%Unchanged
Albion Financial Group125$1.19K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC112$1.07K0.00%−480−81.1%Reduced
True Wealth Design, LLC103$9840.00%00.0%Unchanged
Harbor Investment Advisory, LLC100$9550.00%00.0%Unchanged
Gould Capital, LLC100$9550.00%00.0%Unchanged
EverSource Wealth Advisors, LLC90$8600.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)71$6780.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co54$5160.00%+4+8.0%Added
CIBC Private Wealth Group, LLC48$4580.00%00.0%Unchanged
Ronald Blue Trust, Inc.33$3150.00%00.0%Unchanged
Larson Financial Group LLC26$2480.00%+20+333.3%Added
CoreCap Advisors, LLC23$2200.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd23$2200.00%+23New
SBI Securities Co., Ltd.15$1430.00%−14−48.3%Reduced
IFP Advisors, Inc15$1430.00%00.0%Unchanged
SRS Capital Advisors, Inc.13$1240.00%−5,371−99.8%Reduced
Key Financial Inc12$1150.00%00.0%Unchanged
Clearstead Advisors, LLC10$960.00%−11−52.4%Reduced
MAI Capital Management10$960.00%+10New
Steward Partners Investment Advisory, LLC6$570.00%00.0%Unchanged
Harbour Investments, Inc.1$100.00%00.0%Unchanged
New Millennium Group LLC1$100.00%+1New
Resources Management Corp3$00.00%+3New
Algert Global LLC0$00.00%−445,811−100.0%Sold out
Janney Montgomery Scott LLC0$00.00%−106,898−100.0%Sold out
Monaco Asset Management SAM0$00.00%−70,000−100.0%Sold out
Engineers Gate Manager LP0$00.00%−56,080−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−55,764−100.0%Sold out
HRT Financial LP0$00.00%−31,106−100.0%Sold out
Proficio Capital Partners LLC0$00.00%−30,136−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−30,000−100.0%Sold out
Arizona PSPRS Trust0$00.00%−27,700−100.0%Sold out
Sandia Investment Management LP0$00.00%−29,950−100.0%Sold out
Cambridge Investment Research Advisors, Inc.0$00.00%−27,513−100.0%Sold out
Alps Advisors Inc0$00.00%−25,727−100.0%Sold out
Rock Springs Capital Management LP0$00.00%−25,398−100.0%Sold out
Handelsbanken Fonder AB0$00.00%−20,900−100.0%Sold out
Prosight Management, LP0$00.00%−20,000−100.0%Sold out
Foundation Wealth Management, LLC0$00.00%−19,471−100.0%Sold out
Thrivent Financial for Lutherans0$00.00%−12,980−100.0%Sold out
Jain Global LLC0$00.00%−11,780−100.0%Sold out