Prothena Corp Public Ltd Co
PRTA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001559053
In the last 90 days, Prothena Corp Public Ltd Co insiders filed 4 open-market purchases and 2 sales; 187 institutions reported holding it in 13F filings for Q2 2026, worth $462.7M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Prothena Corp Public Ltd Co as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 182
- 0 vs. Q3 2025
- Shares held
- 47.3M
- +4.86M (+11.5%) vs. Q3 2025
- Total value
- $451.6M
- +$37.8M (+9.1%) vs. Q3 2025
- New holders
- 25
- 62 more added
- Sold out
- 25
- 57 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRTA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $462.7M |
| Q1 2026 | 186 | $459.5M |
| Q4 2025 | 182 | $451.6M |
| Q3 2025 | 187 | $415.8M |
| Q2 2025 | 189 | $253.6M |
| Q1 2025 | 161 | $647.2M |
| Q4 2024 | 171 | $741.3M |
| Q3 2024 | 164 | $855.8M |
| Q2 2024 | 160 | $1.05B |
| Q1 2024 | 169 | $1.33B |
| Q4 2023 | 187 | $1.95B |
| Q3 2023 | 187 | $2.56B |
| Q2 2023 | 196 | $3.54B |
| Q1 2023 | 192 | $2.51B |
| Q4 2022 | 201 | $2.98B |
| Q3 2022 | 183 | $2.69B |
| Q2 2022 | 167 | $1.21B |
| Q1 2022 | 174 | $1.61B |
| Q4 2021 | 196 | $2.12B |
| Q3 2021 | 192 | $2.92B |
| Q2 2021 | 156 | $2.08B |
| Q1 2021 | 146 | $1.00B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Prothena Corp Public Ltd Co; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 7,551,218 | $72.1M | 0.00% | −350,000−4.4% | Reduced |
| BlackRock, Inc. | 4,107,459 | $39.2M | 0.00% | +509,042+14.1% | Added |
| Rubric Capital Management LP | 3,677,331 | $35.1M | 0.42% | +2,136,958+138.7% | Added |
| State Street Corp | 2,267,802 | $21.7M | 0.00% | +1,366,764+151.7% | Added |
| Vanguard Group Inc | 2,140,909 | $20.4M | 0.00% | +91,060+4.4% | Added |
| D. E. Shaw & Co., Inc. | 1,681,369 | $16.1M | 0.01% | +365,951+27.8% | Added |
| Armistice Capital, LLC | 1,500,000 | $14.3M | 0.35% | −324,000−17.8% | Reduced |
| ADAR1 Capital Management, LLC | 1,457,764 | $13.9M | 1.04% | −11,334−0.8% | Reduced |
| Acadian Asset Management LLC | 1,437,358 | $13.7M | 0.02% | +198,116+16.0% | Added |
| Palo Alto Investors LP | 1,320,510 | $12.6M | 1.76% | −3,518−0.3% | Reduced |
| Morgan Stanley | 1,246,775 | $11.9M | 0.00% | +447,101+55.9% | Added |
| Geode Capital Management, LLC | 1,063,069 | $10.2M | 0.00% | +43,586+4.3% | Added |
| Jacobs Levy Equity Management, Inc | 978,011 | $9.34M | 0.04% | +101,483+11.6% | Added |
| Federated Hermes, Inc. | 974,367 | $9.31M | 0.02% | +281,549+40.6% | Added |
| Goldman Sachs Group Inc | 935,333 | $8.93M | 0.00% | +582,112+164.8% | Added |
| Citadel Advisors LLC | 912,382 | $8.71M | 0.01% | +145,277+18.9% | Added |
| Point72 Asset Management, L.P. | 860,018 | $8.21M | 0.01% | +213,272+33.0% | Added |
| Dimensional Fund Advisors LP | 775,207 | $7.40M | 0.00% | −31,781−3.9% | Reduced |
| Nuveen, LLC | 759,107 | $7.25M | 0.00% | +90,817+13.6% | Added |
| Two Sigma Investments, LP | 670,138 | $6.40M | 0.01% | +243,533+57.1% | Added |
| Mariner, LLC | 577,938 | $5.52M | 0.01% | −12,959−2.2% | Reduced |
| Rangeley Capital, LLC | 524,600 | $5.01M | 4.32% | −35,857−6.4% | Reduced |
| Birchview Capital, LP | 441,019 | $4.21M | 2.47% | −108,000−19.7% | Reduced |
| Renaissance Technologies LLC | 435,515 | $4.16M | 0.01% | +64,215+17.3% | Added |
| Jane Street Group, LLC | 428,651 | $4.09M | 0.00% | −191,141−30.8% | Reduced |
| Two Sigma Advisers, LP | 427,400 | $4.08M | 0.01% | +161,700+60.9% | Added |
| Bank of America Corp | 427,360 | $4.08M | 0.00% | +150,264+54.2% | Added |
| UBS Group AG | 426,360 | $4.07M | 0.00% | +25,513+6.4% | Added |
| BNP Paribas Arbitrage, SA | 423,955 | $4.05M | 0.00% | +195,945+85.9% | Added |
| Qube Research & Technologies Ltd | 407,689 | $3.89M | 0.01% | +153,444+60.4% | Added |
| Northern Trust Corp | 363,241 | $3.47M | 0.00% | +28,584+8.5% | Added |
| Charles Schwab Investment Management Inc | 357,335 | $3.41M | 0.00% | +6,514+1.9% | Added |
| Arrowstreet Capital, Limited Partnership | 298,101 | $2.85M | 0.00% | −356,193−54.4% | Reduced |
| Man Group plc | 269,513 | $2.57M | 0.00% | +137,540+104.2% | Added |
| Monimus Capital Management, LP | 254,122 | $2.43M | 1.60% | −3,934−1.5% | Reduced |
| Jump Financial, LLC | 237,828 | $2.27M | 0.03% | +51,581+27.7% | Added |
| Squarepoint Ops LLC | 218,041 | $2.08M | 0.00% | +91,008+71.6% | Added |
| DCF Advisers, LLC | 195,747 | $1.87M | 0.62% | −5,000−2.5% | Reduced |
| AQR Capital Management LLC | 186,785 | $1.78M | 0.00% | −27,757−12.9% | Reduced |
| Barclays PLC | 183,625 | $1.75M | 0.00% | +85,550+87.2% | Added |
| JPMorgan Chase & Co | 169,955 | $1.62M | 0.00% | −565,810−76.9% | Reduced |
| Walleye Capital LLC | 156,035 | $1.49M | 0.01% | +155,972+247,574.6% | Added |
| Bank of New York Mellon Corp | 132,700 | $1.27M | 0.00% | −21,100−13.7% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 125,890 | $1.20M | 0.00% | +125,890 | New |
| Focused Wealth Management, Inc | 107,479 | $1.03M | 0.11% | +50,350+88.1% | Added |
| Diadema Partners LP | 106,539 | $1.02M | 0.61% | +106,539 | New |
| Ameriprise Financial Inc | 105,441 | $1.01M | 0.00% | −95−0.1% | Reduced |
| Los Angeles Capital Management LLC | 95,406 | $999.9K | 0.00% | −24,018−20.1% | Reduced |
| Quantinno Capital Management LP | 103,618 | $989.6K | 0.00% | +2,431+2.4% | Added |
| Y-Intercept (Hong Kong) Ltd | 100,510 | $959.9K | 0.02% | +88,339+725.8% | Added |
| Russell Investments Group, Ltd. | 99,350 | $948.8K | 0.00% | −28,407−22.2% | Reduced |
| Campbell & CO Investment Adviser LLC | 94,155 | $899.2K | 0.04% | +94,155 | New |
| Hennion & Walsh Asset Management, Inc. | 91,284 | $871.8K | 0.03% | +6,686+7.9% | Added |
| ExodusPoint Capital Management, LP | 87,990 | $840.3K | 0.01% | +57,736+190.8% | Added |
| Rafferty Asset Management, LLC | 82,553 | $788.4K | 0.00% | +82,553 | New |
| Price T Rowe Associates Inc | 81,515 | $779.0K | 0.00% | +2,968+3.8% | Added |
| American Century Companies Inc | 78,804 | $752.6K | 0.00% | +6,565+9.1% | Added |
| Assenagon Asset Management S.A. | 76,769 | $733.1K | 0.00% | −12,935−14.4% | Reduced |
| Alliancebernstein L.P. | 69,607 | $664.7K | 0.00% | 00.0% | Unchanged |
| Duncan Williams Asset Management, LLC | 70,281 | $624.8K | 0.16% | −18,058−20.4% | Reduced |
| Martingale Asset Management L P | 63,453 | $606.0K | 0.02% | +63,453 | New |
| SG Americas Securities, LLC | 63,018 | $602.0K | 0.00% | +6,299+11.1% | Added |
| Pinnacle Associates Ltd | 62,724 | $599.0K | 0.01% | −8,537−12.0% | Reduced |
| Creative Planning | 61,969 | $591.8K | 0.00% | −2,171−3.4% | Reduced |
| Caption Management, LLC | 61,009 | $582.6K | 0.03% | 00.0% | Unchanged |
| Wells Fargo & Company | 60,108 | $574.0K | 0.00% | +19,678+48.7% | Added |
| Susquehanna Portfolio Strategies, LLC | 58,853 | $562.0K | 0.01% | +29,878+103.1% | Added |
| Rhumbline Advisers | 56,527 | $539.8K | 0.00% | −5,515−8.9% | Reduced |
| XTX Topco Ltd | 54,881 | $524.1K | 0.01% | +39,073+247.2% | Added |
| Marshall Wace, LLP | 54,778 | $523.1K | 0.00% | +54,778 | New |
| Quinn Opportunity Partners LLC | 50,000 | $477.5K | 0.02% | 00.0% | Unchanged |
| Franklin Resources Inc | 47,251 | $451.2K | 0.00% | −13,921−22.8% | Reduced |
| Massachusetts Financial Services Co | 45,970 | $439.0K | 0.00% | −1,519−3.2% | Reduced |
| Seven Fleet Capital Management LP | 43,300 | $413.5K | 0.28% | +43,300 | New |
| Public Employees Retirement System of Ohio | 42,158 | $402.6K | 0.00% | 00.0% | Unchanged |
| DekaBank Deutsche Girozentrale | 14,000 | $383.0K | 0.00% | 00.0% | Unchanged |
| Deutsche Bank AG | 35,482 | $338.9K | 0.00% | +1,709+5.1% | Added |
| Quadrature Capital Ltd | 31,090 | $296.9K | 0.00% | +3,875+14.2% | Added |
| Profund Advisors LLC | 30,616 | $292.4K | 0.01% | +30,616 | New |
| RBF Capital, LLC | 29,200 | $278.9K | 0.01% | 00.0% | Unchanged |
| Persistent Asset Partners Ltd | 28,589 | $273.0K | 0.13% | +28,589 | New |
| The PNC Financial Services Group, Inc. | 28,128 | $268.6K | 0.00% | +9,991+55.1% | Added |
| Graham Capital Management, L.P. | 27,756 | $265.1K | 0.01% | −25,637−48.0% | Reduced |
| HSBC Holdings PLC | 27,733 | $260.7K | 0.00% | −9,699−25.9% | Reduced |
| Invesco Ltd. | 26,609 | $254.1K | 0.00% | −4,694−15.0% | Reduced |
| Tudor Investment Corp Et Al | 26,473 | $252.8K | 0.00% | −600−2.2% | Reduced |
| Gsa Capital Partners LLP | 26,354 | $252.0K | 0.02% | +26,354 | New |
| Virtus Investment Advisers, Inc. | 25,679 | $245.2K | 0.07% | +3,236+14.4% | Added |
| MetLife Investment Management | 25,501 | $243.5K | 0.00% | +6,139+31.7% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 25,240 | $239.9K | 0.00% | +6,406+34.0% | Added |
| Purkiss Capital Advisors LLC | 25,086 | $239.6K | 0.11% | −300−1.2% | Reduced |
| Edgewood Management LLC | 24,060 | $229.8K | 0.00% | 00.0% | Unchanged |
| Polymer Capital Management (US) LLC | 23,513 | $224.5K | 0.03% | +23,513 | New |
| Headlands Technologies LLC | 23,352 | $223.0K | 0.02% | +23,352 | New |
| Millennium Management LLC | 21,976 | $209.9K | 0.00% | −599,123−96.5% | Reduced |
| Covestor Ltd | 21,793 | $208.0K | 0.11% | −9,639−30.7% | Reduced |
| Mogy Joel R Investment Counsel Inc | 20,750 | $198.2K | 0.01% | 00.0% | Unchanged |
| Intech Investment Management LLC | 20,601 | $196.7K | 0.00% | +1,213+6.3% | Added |
| Trexquant Investment LP | 19,384 | $185.1K | 0.00% | −259,595−93.1% | Reduced |
| Ballentine Partners, LLC | 18,070 | $172.6K | 0.00% | −240−1.3% | Reduced |