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Prothena Corp Public Ltd Co

PRTA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001559053

In the last 90 days, Prothena Corp Public Ltd Co insiders filed 4 open-market purchases and 2 sales; 187 institutions reported holding it in 13F filings for Q2 2026, worth $462.7M in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Prothena Corp Public Ltd Co as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
196
+5 vs. Q3 2021
Shares held
42.8M
+1.95M (+4.8%) vs. Q3 2021
Total value
$2.12B
−$796.5M (−27.3%) vs. Q3 2021
New holders
41
72 more added
Sold out
36
37 more reduced

1 institution that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRTA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 196 institutions
Q1 2021: 146 institutionsQ2 2021: 156 institutionsQ3 2021: 192 institutionsQ4 2021: 196 institutionsQ1 2022: 174 institutionsQ2 2022: 167 institutionsQ3 2022: 183 institutionsQ4 2022: 201 institutionsQ1 2023: 192 institutionsQ2 2023: 196 institutionsQ3 2023: 187 institutionsQ4 2023: 187 institutionsQ1 2024: 169 institutionsQ2 2024: 160 institutionsQ3 2024: 164 institutionsQ4 2024: 171 institutionsQ1 2025: 161 institutionsQ2 2025: 189 institutionsQ3 2025: 187 institutionsQ4 2025: 182 institutionsQ1 2026: 186 institutionsQ2 2026: 187 institutions
Value heldQ4 2021: $2.12B
Q1 2021: $1.00BQ2 2021: $2.08BQ3 2021: $2.92BQ4 2021: $2.12BQ1 2022: $1.61BQ2 2022: $1.21BQ3 2022: $2.69BQ4 2022: $2.98BQ1 2023: $2.51BQ2 2023: $3.54BQ3 2023: $2.56BQ4 2023: $1.95BQ1 2024: $1.33BQ2 2024: $1.05BQ3 2024: $855.8MQ4 2024: $741.3MQ1 2025: $647.2MQ2 2025: $253.6MQ3 2025: $415.8MQ4 2025: $451.6MQ1 2026: $459.5MQ2 2026: $462.7M
Institutions holding PRTA and their total value by quarter
QuarterHoldersValue
Q2 2026187$462.7M
Q1 2026186$459.5M
Q4 2025182$451.6M
Q3 2025187$415.8M
Q2 2025189$253.6M
Q1 2025161$647.2M
Q4 2024171$741.3M
Q3 2024164$855.8M
Q2 2024160$1.05B
Q1 2024169$1.33B
Q4 2023187$1.95B
Q3 2023187$2.56B
Q2 2023196$3.54B
Q1 2023192$2.51B
Q4 2022201$2.98B
Q3 2022183$2.69B
Q2 2022167$1.21B
Q1 2022174$1.61B
Q4 2021196$2.12B
Q3 2021192$2.92B
Q2 2021156$2.08B
Q1 2021146$1.00B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Prothena Corp Public Ltd Co; share changes are against Q3 2021.

Institutions holding PRTA in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
EcoR1 Capital, LLC11,284,280$557.4M17.85%00.0%Unchanged
Price T Rowe Associates Inc5,948,861$293.9M0.03%−113,768−1.9%Reduced
BlackRock Inc.3,872,300$191.3M0.00%+102,596+2.7%Added
FMR LLC2,641,741$130.5M0.01%−7,690−0.3%Reduced
State Street Corp1,972,950$97.5M0.00%+567,706+40.4%Added
Palo Alto Investors LP1,685,282$83.3M5.32%00.0%Unchanged
First Light Asset Management, LLC1,622,941$80.2M5.74%+173,447+12.0%Added
Dimensional Fund Advisors LP1,498,537$74.0M0.02%−81,111−5.1%Reduced
Vanguard Group Inc901,204$44.5M0.00%+32,726+3.8%Added
Redmile Group, LLC765,675$37.8M0.86%−135,816−15.1%Reduced
Rock Springs Capital Management LP647,730$32.0M0.74%−62,700−8.8%Reduced
Geode Capital Management, LLC623,574$30.8M0.00%+3,401+0.5%Added
Nuveen Asset Management, LLC498,164$24.6M0.01%+18,769+3.9%Added
Northern Trust Corp444,819$22.0M0.00%+3,834+0.9%Added
Prosight Management, LP441,000$21.8M14.50%+117,700+36.4%Added
Two Sigma Advisers, LP408,400$20.2M0.05%−65,300−13.8%Reduced
Two Sigma Investments, LP301,454$14.9M0.04%−19,712−6.1%Reduced
Boxer Capital, LLC300,000$14.8M0.59%00.0%Unchanged
Renaissance Technologies LLC266,800$13.2M0.02%+9,600+3.7%Added
UBS Asset Management Americas Inc259,974$12.8M0.00%−19,849−7.1%Reduced
Charles Schwab Investment Management Inc255,614$12.6M0.00%+13,899+5.8%Added
Millennium Management LLC219,891$10.9M0.01%+68,222+45.0%Added
JPMorgan Chase & Co215,342$10.6M0.00%+201,056+1,407.4%Added
Marshall Wace, LLP214,691$10.6M0.02%+145,799+211.6%Added
Goldman Sachs Group Inc214,116$10.6M0.00%+138,207+182.1%Added
Point72 Asset Management, L.P.193,200$9.54M0.04%+31,300+19.3%Added
Morgan Stanley179,531$8.87M0.00%+117,351+188.7%Added
Jacobs Levy Equity Management, Inc177,294$8.76M0.06%+134,067+310.1%Added
Bank of America Corp168,502$8.32M0.00%+134,928+401.9%Added
TD Asset Management Inc163,217$8.06M0.01%+36,323+28.6%Added
ExodusPoint Capital Management, LP162,858$8.04M0.10%+162,858New
Invesco Ltd.157,820$7.80M0.00%−189,604−54.6%Reduced
SG Americas Securities, LLC154,843$7.65M0.05%+38,767+33.4%Added
Bank of New York Mellon Corp152,460$7.53M0.00%+15,173+11.1%Added
Pinnacle Associates Ltd151,214$7.47M0.13%−562−0.4%Reduced
Voloridge Investment Management, LLC145,551$7.19M0.04%+18,294+14.4%Added
Federated Hermes, Inc.120,929$5.97M0.01%−3,738−3.0%Reduced
Rafferty Asset Management, LLC120,668$5.96M0.03%+79,871+195.8%Added
D. E. Shaw & Co., Inc.112,065$5.54M0.01%+78,744+236.3%Added
Citigroup Inc100,288$4.95M0.00%+47,003+88.2%Added
Perceptive Advisors LLC100,000$4.94M0.08%00.0%Unchanged
Parametric Portfolio Associates LLC99,138$4.90M0.00%−25,083−20.2%Reduced
Handelsbanken Fonder AB98,400$4.86M0.02%−11,300−10.3%Reduced
Allspring Global Investments Holdings, LLC97,332$4.81M0.01%+97,332New
Hillsdale Investment Management Inc.93,500$4.62M0.31%00.0%Unchanged
Wellington Management Group LLP93,339$4.61M0.00%+93,339New
Granahan Investment Management Inc90,179$4.46M0.09%+44,875+99.1%Added
Susquehanna International Group, LLP88,806$4.39M0.01%+62,350+235.7%Added
First Trust Advisors LP77,148$3.81M0.00%+77,148New
Norges Bank76,800$3.79M0.00%+76,800New
Prudential Financial Inc76,569$3.78M0.00%−67,880−47.0%Reduced
UBS Group AG74,372$3.67M0.00%−3,145−4.1%Reduced
Swiss National Bank69,400$3.43M0.00%+1,100+1.6%Added
Platinum Investment Management Ltd60,512$2.99M0.08%00.0%Unchanged
Goldstream Capital Management Ltd60,321$2.98M0.73%+60,321New
DCF Advisers, LLC60,000$2.96M1.49%00.0%Unchanged
Alps Advisors Inc53,918$2.66M0.03%−1,288−2.3%Reduced
Healthcare of Ontario Pension Plan Trust Fund52,800$2.61M0.01%+52,800New
Capital Fund Management S.A.52,063$2.57M0.07%+52,063New
Barclays PLC48,880$2.42M0.00%+30,844+171.0%Added
State of New Jersey Common Pension Fund D47,823$2.36M0.01%+3,282+7.4%Added
State of Wisconsin Investment Board47,200$2.33M0.00%+1,400+3.1%Added
California State Teachers Retirement System46,432$2.29M0.00%+2,241+5.1%Added
Bank of Montreal47,546$2.28M0.00%+26,021+120.9%Added
RBF Capital, LLC45,362$2.24M0.14%00.0%Unchanged
Rhumbline Advisers44,423$2.19M0.00%+90.0%Added
Alliancebernstein L.P.44,300$2.19M0.00%−640−1.4%Reduced
Cubist Systematic Strategies, LLC42,605$2.10M0.02%+343+0.8%Added
Massachusetts Financial Services Co41,858$2.07M0.00%−848−2.0%Reduced
Principal Financial Group Inc40,525$2.00M0.00%+8,950+28.3%Added
Birchview Capital, LP40,247$1.99M1.28%00.0%Unchanged
Jump Financial, LLC39,000$1.93M0.12%+11,200+40.3%Added
Ensign Peak Advisors, Inc38,997$1.93M0.00%+16,835+76.0%Added
Wells Fargo & Company38,188$1.89M0.00%−18,143−32.2%Reduced
Verition Fund Management LLC35,878$1.77M0.02%+35,878New
Gotham Asset Management, LLC34,658$1.71M0.06%+16,485+90.7%Added
New York Life Investments Alternatives33,212$1.64M1.10%+8,363+33.7%Added
New York State Common Retirement Fund30,781$1.52M0.00%+4,421+16.8%Added
HighVista Strategies LLC28,078$1.39M1.10%+28,078New
Citadel Advisors LLC27,693$1.37M0.00%−75,812−73.2%Reduced
Edgewood Management LLC25,000$1.24M0.00%00.0%Unchanged
Deutsche Bank AG24,624$1.22M0.00%−7,024−22.2%Reduced
Russell Investments Group, Ltd.23,711$1.17M0.00%+20,215+578.2%Added
Credit Suisse AG23,572$1.17M0.00%−1,660−6.6%Reduced
Robeco Institutional Asset Management B.V.21,932$1.08M0.00%+4,972+29.3%Added
Thrivent Financial for Lutherans20,870$1.03M0.00%+20,870New
Qube Research & Technologies Ltd19,833$980.0K0.01%+19,833New
Susquehanna Fundamental Investments, LLC19,290$953.0K0.02%−10,860−36.0%Reduced
American International Group, Inc.19,212$949.0K0.00%+82+0.4%Added
Jennison Associates LLC18,631$920.0K0.00%+4,360+30.6%Added
Manufacturers Life Insurance Company, The17,366$858.0K0.00%+83+0.5%Added
Allianz Asset Management GmbH16,595$815.0K0.00%+16,595New
STRS Ohio16,400$810.0K0.00%+2,700+19.7%Added
State Board of Administration of Florida Retirement System16,066$794.0K0.00%−145−0.9%Reduced
Hussman Strategic Advisors, Inc.15,600$771.0K0.17%+15,600New
Aviva PLC15,595$770.0K0.00%+15,595New
Royal Bank of Canada15,302$756.0K0.00%+2,280+17.5%Added
International Biotechnology Trust PLC15,000$741.0K0.17%+15,000New
ProShare Advisors LLC14,456$715.0K0.00%+355+2.5%Added
Legal & General Group Plc14,448$713.0K0.00%+366+2.6%Added