Prothena Corp Public Ltd Co
PRTA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001559053
In the last 90 days, Prothena Corp Public Ltd Co insiders filed 4 open-market purchases and 2 sales; 187 institutions reported holding it in 13F filings for Q2 2026, worth $462.7M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Prothena Corp Public Ltd Co as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 187
- −1 vs. Q2 2025
- Shares held
- 42.6M
- +896.5K (+2.1%) vs. Q2 2025
- Total value
- $415.8M
- +$162.6M (+64.2%) vs. Q2 2025
- New holders
- 31
- 58 more added
- Sold out
- 32
- 61 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRTA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $462.7M |
| Q1 2026 | 186 | $459.5M |
| Q4 2025 | 182 | $451.6M |
| Q3 2025 | 187 | $415.8M |
| Q2 2025 | 189 | $253.6M |
| Q1 2025 | 161 | $647.2M |
| Q4 2024 | 171 | $741.3M |
| Q3 2024 | 164 | $855.8M |
| Q2 2024 | 160 | $1.05B |
| Q1 2024 | 169 | $1.33B |
| Q4 2023 | 187 | $1.95B |
| Q3 2023 | 187 | $2.56B |
| Q2 2023 | 196 | $3.54B |
| Q1 2023 | 192 | $2.51B |
| Q4 2022 | 201 | $2.98B |
| Q3 2022 | 183 | $2.69B |
| Q2 2022 | 167 | $1.21B |
| Q1 2022 | 174 | $1.61B |
| Q4 2021 | 196 | $2.12B |
| Q3 2021 | 192 | $2.92B |
| Q2 2021 | 156 | $2.08B |
| Q1 2021 | 146 | $1.00B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Prothena Corp Public Ltd Co; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 7,901,218 | $77.1M | 0.00% | 00.0% | Unchanged |
| BlackRock, Inc. | 3,598,417 | $35.1M | 0.00% | −340,981−8.7% | Reduced |
| Vanguard Group Inc | 2,049,849 | $20.0M | 0.00% | −126,378−5.8% | Reduced |
| Armistice Capital, LLC | 1,824,000 | $17.8M | 0.56% | −412,000−18.4% | Reduced |
| Rubric Capital Management LP | 1,540,373 | $15.0M | 0.20% | +1,540,373 | New |
| ADAR1 Capital Management, LLC | 1,469,098 | $14.3M | 1.42% | −1,905,911−56.5% | Reduced |
| Palo Alto Investors LP | 1,324,028 | $12.9M | 2.39% | +49,275+3.9% | Added |
| D. E. Shaw & Co., Inc. | 1,315,418 | $12.8M | 0.01% | +923,923+236.0% | Added |
| Acadian Asset Management LLC | 1,239,242 | $12.1M | 0.02% | +221,065+21.7% | Added |
| Geode Capital Management, LLC | 1,019,483 | $9.95M | 0.00% | +86,037+9.2% | Added |
| State Street Corp | 901,038 | $8.79M | 0.00% | −103,964−10.3% | Reduced |
| Jacobs Levy Equity Management, Inc | 876,528 | $8.55M | 0.03% | +183,374+26.5% | Added |
| Dimensional Fund Advisors LP | 806,988 | $7.88M | 0.00% | −155,351−16.1% | Reduced |
| Morgan Stanley | 799,674 | $7.80M | 0.00% | −153,582−16.1% | Reduced |
| Citadel Advisors LLC | 767,105 | $7.49M | 0.01% | −380,517−33.2% | Reduced |
| JPMorgan Chase & Co | 735,765 | $7.18M | 0.00% | +608,814+479.6% | Added |
| Federated Hermes, Inc. | 692,818 | $6.76M | 0.01% | −488,269−41.3% | Reduced |
| Nuveen, LLC | 668,290 | $6.52M | 0.00% | +546,135+447.1% | Added |
| Arrowstreet Capital, Limited Partnership | 654,294 | $6.39M | 0.00% | +654,294 | New |
| Point72 Asset Management, L.P. | 646,746 | $6.31M | 0.01% | +646,746 | New |
| Millennium Management LLC | 621,099 | $6.06M | 0.00% | +450,520+264.1% | Added |
| Jane Street Group, LLC | 619,792 | $6.05M | 0.01% | +502,339+427.7% | Added |
| Mariner, LLC | 590,897 | $5.77M | 0.01% | +204,189+52.8% | Added |
| Rangeley Capital, LLC | 560,457 | $5.47M | 5.14% | −154,910−21.7% | Reduced |
| Birchview Capital, LP | 549,019 | $5.36M | 4.05% | +98,000+21.7% | Added |
| Algert Global LLC | 445,811 | $4.35M | 0.07% | +397,661+825.9% | Added |
| Two Sigma Investments, LP | 426,605 | $4.16M | 0.01% | +225,155+111.8% | Added |
| UBS Group AG | 400,847 | $3.91M | 0.00% | +340,183+560.8% | Added |
| Renaissance Technologies LLC | 371,300 | $3.62M | 0.00% | +281,100+311.6% | Added |
| Goldman Sachs Group Inc | 353,221 | $3.45M | 0.00% | −175,102−33.1% | Reduced |
| Charles Schwab Investment Management Inc | 350,821 | $3.42M | 0.00% | +75,737+27.5% | Added |
| Northern Trust Corp | 334,657 | $3.27M | 0.00% | +1030.0% | Added |
| Trexquant Investment LP | 278,979 | $2.72M | 0.03% | −273,847−49.5% | Reduced |
| Bank of America Corp | 277,096 | $2.70M | 0.00% | +66,151+31.4% | Added |
| Two Sigma Advisers, LP | 265,700 | $2.59M | 0.01% | +125,900+90.1% | Added |
| Monimus Capital Management, LP | 258,056 | $2.52M | 1.87% | +51,581+25.0% | Added |
| Qube Research & Technologies Ltd | 254,245 | $2.48M | 0.00% | −160,583−38.7% | Reduced |
| BNP Paribas Arbitrage, SA | 228,010 | $2.23M | 0.00% | +181,166+386.7% | Added |
| AQR Capital Management LLC | 214,542 | $2.09M | 0.00% | +214,542 | New |
| DCF Advisers, LLC | 200,747 | $1.96M | 0.74% | +44,247+28.3% | Added |
| Cubist Systematic Strategies, LLC | 190,949 | $1.86M | 0.03% | −310,815−61.9% | Reduced |
| Jump Financial, LLC | 186,247 | $1.82M | 0.02% | +186,247 | New |
| Susquehanna International Group, LLP | 157,447 | $1.54M | 0.00% | +65,497+71.2% | Added |
| Bank of New York Mellon Corp | 153,800 | $1.50M | 0.00% | +5,450+3.7% | Added |
| Man Group plc | 131,973 | $1.29M | 0.00% | +89,221+208.7% | Added |
| Russell Investments Group, Ltd. | 127,757 | $1.25M | 0.00% | +31,561+32.8% | Added |
| Squarepoint Ops LLC | 127,033 | $1.24M | 0.00% | −82,216−39.3% | Reduced |
| Los Angeles Capital Management LLC | 119,424 | $1.17M | 0.00% | +102,722+615.0% | Added |
| Janney Montgomery Scott LLC | 106,898 | $1.04M | 0.00% | +106,898 | New |
| Ameriprise Financial Inc | 105,536 | $1.03M | 0.00% | −46,007−30.4% | Reduced |
| Quantinno Capital Management LP | 101,187 | $987.6K | 0.00% | +41,569+69.7% | Added |
| Barclays PLC | 98,075 | $957.2K | 0.00% | −17,773−15.3% | Reduced |
| Assenagon Asset Management S.A. | 89,704 | $875.5K | 0.00% | +89,704 | New |
| Duncan Williams Asset Management, LLC | 88,339 | $862.2K | 0.24% | 00.0% | Unchanged |
| Hennion & Walsh Asset Management, Inc. | 84,598 | $825.7K | 0.03% | −1,556−1.8% | Reduced |
| Price T Rowe Associates Inc | 78,547 | $767.0K | 0.00% | +7,500+10.6% | Added |
| American Century Companies Inc | 72,239 | $705.1K | 0.00% | +12,274+20.5% | Added |
| Pinnacle Associates Ltd | 71,261 | $695.5K | 0.01% | −2,818−3.8% | Reduced |
| Monaco Asset Management SAM | 70,000 | $683.2K | 0.25% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 69,607 | $679.4K | 0.00% | −17,980−20.5% | Reduced |
| Creative Planning | 64,140 | $626.0K | 0.00% | +13,571+26.8% | Added |
| Rhumbline Advisers | 62,042 | $605.5K | 0.00% | −963−1.5% | Reduced |
| Franklin Resources Inc | 61,172 | $597.0K | 0.00% | +5,094+9.1% | Added |
| Caption Management, LLC | 61,009 | $595.4K | 0.03% | −4,091−6.3% | Reduced |
| Focused Wealth Management, Inc | 57,129 | $557.6K | 0.06% | +25,000+77.8% | Added |
| SG Americas Securities, LLC | 56,719 | $554.0K | 0.00% | +4,778+9.2% | Added |
| Engineers Gate Manager LP | 56,080 | $547.3K | 0.01% | +15,113+36.9% | Added |
| Balyasny Asset Management LLC | 55,764 | $544.3K | 0.00% | −520,028−90.3% | Reduced |
| Graham Capital Management, L.P. | 53,393 | $521.1K | 0.02% | +19,351+56.8% | Added |
| Quinn Opportunity Partners LLC | 50,000 | $488.0K | 0.04% | 00.0% | Unchanged |
| Massachusetts Financial Services Co | 47,489 | $463.5K | 0.00% | +3,125+7.0% | Added |
| Fox Run Management, L.L.C. | 44,332 | $432.7K | 0.07% | +44,332 | New |
| Public Employees Retirement System of Ohio | 42,158 | $411.5K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 42,044 | $410.0K | 0.01% | −1,220−2.8% | Reduced |
| Wells Fargo & Company | 40,430 | $394.6K | 0.00% | −790−1.9% | Reduced |
| HSBC Holdings PLC | 37,432 | $364.6K | 0.00% | −8,615−18.7% | Reduced |
| Deutsche Bank AG | 33,773 | $329.6K | 0.00% | −5,828−14.7% | Reduced |
| Covestor Ltd | 31,432 | $307.0K | 0.17% | −10,863−25.7% | Reduced |
| Invesco Ltd. | 31,303 | $305.5K | 0.00% | −5,582−15.1% | Reduced |
| HRT Financial LP | 31,106 | $303.0K | 0.00% | +31,106 | New |
| ExodusPoint Capital Management, LP | 30,254 | $295.3K | 0.00% | −28,664−48.7% | Reduced |
| Proficio Capital Partners LLC | 30,136 | $294.1K | 0.02% | +30,136 | New |
| Boothbay Fund Management, LLC | 30,000 | $292.8K | 0.01% | +30,000 | New |
| Arizona PSPRS Trust | 27,700 | $292.5K | 0.01% | +27,700 | New |
| Sandia Investment Management LP | 29,950 | $292.3K | 0.87% | +29,950 | New |
| RBF Capital, LLC | 29,200 | $285.0K | 0.01% | 00.0% | Unchanged |
| Susquehanna Portfolio Strategies, LLC | 28,975 | $282.8K | 0.00% | −42,693−59.6% | Reduced |
| STRS Ohio | 28,800 | $281.1K | 0.00% | +12,400+75.6% | Added |
| Cambridge Investment Research Advisors, Inc. | 27,513 | $269.0K | 0.00% | +202+0.7% | Added |
| Quadrature Capital Ltd | 27,215 | $265.3K | 0.00% | +3,463+14.6% | Added |
| Tudor Investment Corp Et Al | 27,073 | $264.2K | 0.00% | −926−3.3% | Reduced |
| Alps Advisors Inc | 25,727 | $251.1K | 0.00% | −3,301−11.4% | Reduced |
| Rock Springs Capital Management LP | 25,398 | $247.9K | 0.01% | −467,203−94.8% | Reduced |
| Purkiss Capital Advisors LLC | 25,386 | $247.8K | 0.12% | +482+1.9% | Added |
| Edgewood Management LLC | 24,060 | $234.8K | 0.00% | 00.0% | Unchanged |
| Virtus Investment Advisers, Inc. | 22,443 | $219.0K | 0.06% | +3,896+21.0% | Added |
| Raymond James Financial Inc | 22,032 | $215.0K | 0.00% | +8,536+63.2% | Added |
| Atom Investors LP | 21,315 | $208.0K | 0.02% | +21,315 | New |
| Handelsbanken Fonder AB | 20,900 | $204.0K | 0.00% | 00.0% | Unchanged |
| Mogy Joel R Investment Counsel Inc | 20,750 | $202.5K | 0.01% | 00.0% | Unchanged |