Skip to main content

Prothena Corp Public Ltd Co

PRTA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001559053

In the last 90 days, Prothena Corp Public Ltd Co insiders filed 4 open-market purchases and 2 sales; 187 institutions reported holding it in 13F filings for Q2 2026, worth $462.7M in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Prothena Corp Public Ltd Co as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
161
−8 vs. Q4 2024
Shares held
52.3M
−1.06M (−2.0%) vs. Q4 2024
Total value
$647.2M
−$91.9M (−12.4%) vs. Q4 2024
New holders
17
42 more added
Sold out
25
58 more reduced

2 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRTA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 161 institutions
Q1 2021: 146 institutionsQ2 2021: 156 institutionsQ3 2021: 192 institutionsQ4 2021: 196 institutionsQ1 2022: 174 institutionsQ2 2022: 167 institutionsQ3 2022: 183 institutionsQ4 2022: 201 institutionsQ1 2023: 192 institutionsQ2 2023: 196 institutionsQ3 2023: 187 institutionsQ4 2023: 187 institutionsQ1 2024: 169 institutionsQ2 2024: 160 institutionsQ3 2024: 164 institutionsQ4 2024: 171 institutionsQ1 2025: 161 institutionsQ2 2025: 189 institutionsQ3 2025: 187 institutionsQ4 2025: 182 institutionsQ1 2026: 186 institutionsQ2 2026: 187 institutions
Value heldQ1 2025: $647.2M
Q1 2021: $1.00BQ2 2021: $2.08BQ3 2021: $2.92BQ4 2021: $2.12BQ1 2022: $1.61BQ2 2022: $1.21BQ3 2022: $2.69BQ4 2022: $2.98BQ1 2023: $2.51BQ2 2023: $3.54BQ3 2023: $2.56BQ4 2023: $1.95BQ1 2024: $1.33BQ2 2024: $1.05BQ3 2024: $855.8MQ4 2024: $741.3MQ1 2025: $647.2MQ2 2025: $253.6MQ3 2025: $415.8MQ4 2025: $451.6MQ1 2026: $459.5MQ2 2026: $462.7M
Institutions holding PRTA and their total value by quarter
QuarterHoldersValue
Q2 2026187$462.7M
Q1 2026186$459.5M
Q4 2025182$451.6M
Q3 2025187$415.8M
Q2 2025189$253.6M
Q1 2025161$647.2M
Q4 2024171$741.3M
Q3 2024164$855.8M
Q2 2024160$1.05B
Q1 2024169$1.33B
Q4 2023187$1.95B
Q3 2023187$2.56B
Q2 2023196$3.54B
Q1 2023192$2.51B
Q4 2022201$2.98B
Q3 2022183$2.69B
Q2 2022167$1.21B
Q1 2022174$1.61B
Q4 2021196$2.12B
Q3 2021192$2.92B
Q2 2021156$2.08B
Q1 2021146$1.00B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Prothena Corp Public Ltd Co; share changes are against Q4 2024.

Institutions holding PRTA in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
EcoR1 Capital, LLC11,584,280$143.4M8.53%00.0%Unchanged
FMR LLC7,941,402$98.3M0.01%−129,907−1.6%Reduced
Wellington Management Group LLP5,199,528$64.3M0.01%+68,652+1.3%Added
BlackRock, Inc.4,042,301$50.0M0.00%−80,075−1.9%Reduced
Price T Rowe Associates Inc3,455,856$42.8M0.01%−229,852−6.2%Reduced
Armistice Capital, LLC2,196,000$27.2M0.73%−40,000−1.8%Reduced
Palo Alto Investors LP1,659,734$20.5M3.91%−78,230−4.5%Reduced
State Street Corp1,521,364$18.8M0.00%−340,277−18.3%Reduced
Siren, L.L.C.1,283,555$15.9M0.90%+183,715+16.7%Added
Vanguard Group Inc1,269,271$15.7M0.00%−134,567−9.6%Reduced
Geode Capital Management, LLC1,014,792$12.6M0.00%+50,484+5.2%Added
Dimensional Fund Advisors LP863,148$10.7M0.00%−1,685−0.2%Reduced
Morgan Stanley719,988$8.91M0.00%+498+0.1%Added
Boxer Capital Management, LLC690,000$8.54M2.57%00.0%Unchanged
Finepoint Capital LP640,071$7.92M1.34%−17,000−2.6%Reduced
Federated Hermes, Inc.546,255$6.76M0.01%−199,922−26.8%Reduced
Goldman Sachs Group Inc510,462$6.32M0.00%−46,064−8.3%Reduced
Rock Springs Capital Management LP492,601$6.10M0.35%−152,000−23.6%Reduced
Prosight Management, LP408,122$5.05M1.66%−10,000−2.4%Reduced
UBS Asset Management Americas Inc381,652$4.72M0.00%+1440.0%Added
Northern Trust Corp373,703$4.62M0.00%−30,793−7.6%Reduced
JPMorgan Chase & Co371,965$4.60M0.00%−15,385−4.0%Reduced
Mariner, LLC354,650$4.39M0.01%+10,733+3.1%Added
Birchview Capital, LP332,974$4.12M3.58%+28,400+9.3%Added
Charles Schwab Investment Management Inc319,607$3.96M0.00%−7,544−2.3%Reduced
Nordea Investment Management AB307,987$3.74M0.00%+307,987New
UBS Group AG244,479$3.03M0.00%−126,808−34.2%Reduced
Renaissance Technologies LLC239,900$2.97M0.00%+38,000+18.8%Added
DCF Advisers, LLC195,000$2.41M1.30%+91,500+88.4%Added
PDT Partners, LLC150,316$1.86M0.13%+23,113+18.2%Added
Nuveen, LLC149,961$1.86M0.00%+149,961New
Bank of New York Mellon Corp146,009$1.81M0.00%−4,229−2.8%Reduced
Jane Street Group, LLC132,640$1.64M0.00%+77,112+138.9%Added
Bank of America Corp131,986$1.63M0.00%+12,979+10.9%Added
Pinnacle Associates Ltd100,259$1.24M0.02%−2,822−2.7%Reduced
Deutsche Bank AG95,810$1.19M0.00%−160−0.2%Reduced
Connor, Clark & Lunn Investment Management Ltd.91,482$1.13M0.00%−358−0.4%Reduced
Citadel Advisors LLC89,399$1.11M0.00%+47,881+115.3%Added
Duncan Williams Asset Management, LLC88,339$1.09M0.39%+19,140+27.7%Added
Barclays PLC83,381$1.03M0.00%−21,957−20.8%Reduced
Hennion & Walsh Asset Management, Inc.77,637$960.8K0.04%+25,353+48.5%Added
Susquehanna International Group, LLP77,243$955.9K0.00%+51,974+205.7%Added
Susquehanna Fundamental Investments, LLC74,772$925.3K0.02%−5,905−7.3%Reduced
SG Americas Securities, LLC72,559$898.0K0.00%+34,947+92.9%Added
Swiss National Bank68,700$850.2K0.00%00.0%Unchanged
Rhumbline Advisers66,079$817.7K0.00%−1,036−1.5%Reduced
Citigroup Inc65,826$814.6K0.00%−2,607−3.8%Reduced
Manufacturers Life Insurance Company, The65,231$807.2K0.00%−4,953−7.1%Reduced
TD Asset Management Inc62,694$775.8K0.00%−2,000−3.1%Reduced
Norges Bank57,454$711.0K0.00%00.0%Unchanged
Millennium Management LLC52,467$649.3K0.00%−70,538−57.3%Reduced
Alliancebernstein L.P.46,753$578.6K0.00%00.0%Unchanged
Wells Fargo & Company45,889$567.9K0.00%−6,934−13.1%Reduced
Rafferty Asset Management, LLC43,978$544.2K0.00%−33,694−43.4%Reduced
Massachusetts Financial Services Co43,816$542.2K0.00%−999−2.2%Reduced
Legal & General Group Plc41,354$511.8K0.00%−51−0.1%Reduced
ExodusPoint Capital Management, LP41,272$511.0K0.01%+41,272New
Thrivent Financial for Lutherans38,626$478.0K0.00%00.0%Unchanged
Alps Advisors Inc37,956$469.7K0.00%−5,554−12.8%Reduced
Invesco Ltd.37,638$465.8K0.00%−5,208−12.2%Reduced
American Century Companies Inc34,836$431.1K0.00%+4,437+14.6%Added
Intech Investment Management LLC33,375$413.0K0.00%+10,992+49.1%Added
California State Teachers Retirement System33,243$411.4K0.00%00.0%Unchanged
Focused Wealth Management, Inc32,129$397.6K0.05%00.0%Unchanged
RBF Capital, LLC29,200$361.4K0.02%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.27,334$339.8K0.00%+65+0.2%Added
MetLife Investment Management25,402$314.4K0.00%−471−1.8%Reduced
Edgewood Management LLC24,060$297.7K0.00%00.0%Unchanged
Ensign Peak Advisors, Inc21,643$267.8K0.00%00.0%Unchanged
Purkiss Capital Advisors LLC21,629$267.7K0.20%+10,900+101.6%Added
Dark Forest Capital Management LP21,059$260.6K0.01%+21,059New
Handelsbanken Fonder AB20,900$259.0K0.00%00.0%Unchanged
Corebridge Financial, Inc.20,831$257.8K0.00%−309−1.5%Reduced
Franklin Resources Inc19,747$244.4K0.00%+60+0.3%Added
Foundation Wealth Management, LLC19,471$241.0K0.19%00.0%Unchanged
Janus Henderson Group PLC18,047$237.2K0.00%00.0%Unchanged
Jacobs Levy Equity Management, Inc18,553$229.6K0.00%+18,553New
D. E. Shaw & Co., Inc.17,803$220.3K0.00%+17,803New
Man Group plc17,000$210.4K0.00%−60,430−78.0%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)16,040$198.5K0.00%+10+0.1%Added
Two Sigma Investments, LP16,033$198.4K0.00%−22,361−58.2%Reduced
State Board of Administration of Florida Retirement System15,386$190.4K0.00%00.0%Unchanged
Shelton Capital Management15,233$188.5K0.00%+15,233New
DekaBank Deutsche Girozentrale14,000$180.0K0.00%00.0%Unchanged
New York State Common Retirement Fund14,279$176.7K0.00%00.0%Unchanged
HRT Financial LP14,036$173.0K0.00%+14,036New
Commonwealth Equity Services, LLC13,320$165.0K0.00%+13,320New
Cresset Asset Management, LLC13,125$162.4K0.00%−6,309−32.5%Reduced
HSBC Holdings PLC13,088$159.7K0.00%−11,091−45.9%Reduced
Cary Street Partners Financial LLC12,500$154.7K0.00%00.0%Unchanged
Raymond James Financial Inc12,487$154.5K0.00%−624−4.8%Reduced
Virtus Investment Advisers, Inc.11,891$147.2K0.04%+11,891New
Voya Investment Management LLC11,684$144.6K0.00%−1,145−8.9%Reduced
ProShare Advisors LLC11,632$143.9K0.00%−2,892−19.9%Reduced
China Universal Asset Management Co., Ltd.10,797$133.6K0.01%−612−5.4%Reduced
Creative Planning10,690$132.3K0.00%−5,371−33.4%Reduced
Cambridge Investment Research Advisors, Inc.10,164$126.0K0.00%+10,164New
Police & Firemen's Retirement System of New Jersey10,113$125.1K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA9,577$118.5K0.00%−87,806−90.2%Reduced
Chicago Partners Investment Group LLC14,512$105.8K0.00%+3,315+29.6%Added