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Prothena Corp Public Ltd Co

PRTA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001559053

In the last 90 days, Prothena Corp Public Ltd Co insiders filed 4 open-market purchases and 2 sales; 187 institutions reported holding it in 13F filings for Q2 2026, worth $462.7M in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Prothena Corp Public Ltd Co as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
201
+21 vs. Q3 2022
Shares held
49.4M
+4.96M (+11.2%) vs. Q3 2022
Total value
$2.98B
+$282.3M (+10.5%) vs. Q3 2022
New holders
44
77 more added
Sold out
23
51 more reduced

3 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRTA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 201 institutions
Q1 2021: 146 institutionsQ2 2021: 156 institutionsQ3 2021: 192 institutionsQ4 2021: 196 institutionsQ1 2022: 174 institutionsQ2 2022: 167 institutionsQ3 2022: 183 institutionsQ4 2022: 201 institutionsQ1 2023: 192 institutionsQ2 2023: 196 institutionsQ3 2023: 187 institutionsQ4 2023: 187 institutionsQ1 2024: 169 institutionsQ2 2024: 160 institutionsQ3 2024: 164 institutionsQ4 2024: 171 institutionsQ1 2025: 161 institutionsQ2 2025: 189 institutionsQ3 2025: 187 institutionsQ4 2025: 182 institutionsQ1 2026: 186 institutionsQ2 2026: 187 institutions
Value heldQ4 2022: $2.98B
Q1 2021: $1.00BQ2 2021: $2.08BQ3 2021: $2.92BQ4 2021: $2.12BQ1 2022: $1.61BQ2 2022: $1.21BQ3 2022: $2.69BQ4 2022: $2.98BQ1 2023: $2.51BQ2 2023: $3.54BQ3 2023: $2.56BQ4 2023: $1.95BQ1 2024: $1.33BQ2 2024: $1.05BQ3 2024: $855.8MQ4 2024: $741.3MQ1 2025: $647.2MQ2 2025: $253.6MQ3 2025: $415.8MQ4 2025: $451.6MQ1 2026: $459.5MQ2 2026: $462.7M
Institutions holding PRTA and their total value by quarter
QuarterHoldersValue
Q2 2026187$462.7M
Q1 2026186$459.5M
Q4 2025182$451.6M
Q3 2025187$415.8M
Q2 2025189$253.6M
Q1 2025161$647.2M
Q4 2024171$741.3M
Q3 2024164$855.8M
Q2 2024160$1.05B
Q1 2024169$1.33B
Q4 2023187$1.95B
Q3 2023187$2.56B
Q2 2023196$3.54B
Q1 2023192$2.51B
Q4 2022201$2.98B
Q3 2022183$2.69B
Q2 2022167$1.21B
Q1 2022174$1.61B
Q4 2021196$2.12B
Q3 2021192$2.92B
Q2 2021156$2.08B
Q1 2021146$1.00B

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Prothena Corp Public Ltd Co; share changes are against Q3 2022.

Institutions holding PRTA in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
EcoR1 Capital, LLC11,584,280$698.0M21.27%00.0%Unchanged
FMR LLC3,947,272$237.8M0.02%+784,854+24.8%Added
BlackRock Inc.3,485,068$210.0M0.01%+346,324+11.0%Added
Price T Rowe Associates Inc3,205,903$193.2M0.03%+223,962+7.5%Added
Avidity Partners Management LP2,953,000$177.9M4.16%+986,000+50.1%Added
State Street Corp2,051,960$123.6M0.01%+170,166+9.0%Added
Wellington Management Group LLP1,764,893$106.3M0.02%+1,333,384+309.0%Added
Palo Alto Investors LP1,658,577$99.9M8.52%+8,800+0.5%Added
First Light Asset Management, LLC1,535,599$92.5M8.59%−3,079−0.2%Reduced
Janus Henderson Group PLC1,432,323$86.3M0.06%+1,279,375+836.5%Added
Dimensional Fund Advisors LP1,320,501$79.6M0.03%−163,404−11.0%Reduced
T. Rowe Price Investment Management, Inc.927,959$55.9M0.04%+79,997+9.4%Added
PFM Health Sciences, LP875,464$52.7M2.23%+35,226+4.2%Added
Vanguard Group Inc870,134$52.4M0.00%+62,174+7.7%Added
Rock Springs Capital Management LP753,462$45.4M1.09%+75,000+11.1%Added
Geode Capital Management, LLC715,601$43.1M0.01%+79,877+12.6%Added
Nuveen Asset Management, LLC572,790$34.5M0.01%+82,338+16.8%Added
Renaissance Technologies LLC474,900$28.6M0.04%−162,000−25.4%Reduced
Eventide Asset Management, LLC438,732$26.4M0.52%+208,732+90.8%Added
JPMorgan Chase & Co404,551$24.4M0.00%+122,369+43.4%Added
Maple Rock Capital Partners Inc.399,414$24.1M3.55%00.0%Unchanged
Northern Trust Corp361,585$21.8M0.00%+14,437+4.2%Added
Prosight Management, LP330,000$19.9M11.12%+8,907+2.8%Added
Two Sigma Advisers, LP327,000$19.7M0.06%−8,000−2.4%Reduced
Finepoint Capital LP322,900$19.5M6.29%+17,500+5.7%Added
Point72 Asset Management, L.P.311,500$18.8M0.07%+143,100+85.0%Added
Charles Schwab Investment Management Inc300,850$18.1M0.01%+15,108+5.3%Added
Boxer Capital, LLC300,000$18.1M0.97%00.0%Unchanged
Perceptive Advisors LLC237,646$14.3M0.41%+7,646+3.3%Added
UBS Asset Management Americas Inc228,368$13.8M0.01%−14,642−6.0%Reduced
Goldman Sachs Group Inc216,055$13.0M0.00%−50,482−18.9%Reduced
Millennium Management LLC213,610$12.9M0.01%+84,173+65.0%Added
Suvretta Capital Management, LLC206,448$12.4M0.52%−110,083−34.8%Reduced
Two Sigma Investments, LP203,435$12.3M0.04%+67,750+49.9%Added
Granahan Investment Management Inc199,926$12.0M0.37%+58,818+41.7%Added
Morgan Stanley180,403$10.9M0.00%+13,904+8.4%Added
Rafferty Asset Management, LLC138,353$8.34M0.07%+31,687+29.7%Added
Pinnacle Associates Ltd137,571$8.29M0.18%−2,525−1.8%Reduced
Bank of New York Mellon Corp136,997$8.25M0.00%−3,195−2.3%Reduced
Frazier Life Sciences Management, L.P.127,900$7.71M0.48%+127,900New
Birchview Capital, LP127,195$7.66M5.41%+8,250+6.9%Added
Ensign Peak Advisors, Inc125,422$7.56M0.02%+63,665+103.1%Added
Woodline Partners LP123,623$7.45M0.10%+123,623New
Bank of America Corp121,671$7.33M0.00%+38,574+46.4%Added
Sectoral Asset Management Inc115,200$6.94M1.34%+115,200New
Atika Capital Management LLC91,178$5.49M0.84%+91,178New
UBS Group AG91,069$5.49M0.00%+84,920+1,381.0%Added
TD Asset Management Inc81,513$4.91M0.01%+12,974+18.9%Added
Barclays PLC79,339$4.78M0.00%+11,277+16.6%Added
Swiss National Bank79,300$4.78M0.00%+2,100+2.7%Added
SG Americas Securities, LLC78,772$4.75M0.07%−56,816−41.9%Reduced
Hillsdale Investment Management Inc.77,500$4.67M0.39%+77,500New
EAM Global Investors LLC76,653$4.62M1.19%00.0%Unchanged
Paradigm Biocapital Advisors LP75,000$4.52M0.53%−160,826−68.2%Reduced
DCF Advisers, LLC74,100$4.46M3.45%+6,100+9.0%Added
Silverarc Capital Management, LLC71,706$4.32M1.49%−38,294−34.8%Reduced
Putnam Investments LLC65,394$3.94M0.01%+50,638+343.2%Added
Pura Vida Investments, LLC64,000$3.86M0.65%+64,000New
Citigroup Inc63,400$3.82M0.01%−34,744−35.4%Reduced
First Trust Advisors LP62,396$3.76M0.00%+23,588+60.8%Added
Connor, Clark & Lunn Investment Management Ltd.60,432$3.64M0.02%+32,876+119.3%Added
Norges Bank59,259$3.57M0.00%+23,859+67.4%Added
Principal Financial Group Inc56,007$3.37M0.00%+36,992+194.5%Added
Manufacturers Life Insurance Company, The55,062$3.29M0.00%+2,031+3.8%Added
RBF Capital, LLC54,362$3.27M0.25%00.0%Unchanged
EAM Investors, LLC53,346$3.21M0.67%−291−0.5%Reduced
Handelsbanken Fonder AB52,000$3.13M0.02%−33,700−39.3%Reduced
Rhumbline Advisers49,718$3.00M0.00%+2,827+6.0%Added
Jennison Associates LLC49,241$2.97M0.00%+49,241New
Alliancebernstein L.P.44,866$2.70M0.00%−500−1.1%Reduced
California State Teachers Retirement System43,220$2.60M0.00%+1,017+2.4%Added
Invesco Ltd.42,304$2.55M0.00%+24,822+142.0%Added
Platinum Investment Management Ltd41,508$2.50M0.10%−7,406−15.1%Reduced
Cubist Systematic Strategies, LLC40,719$2.45M0.02%+22,999+129.8%Added
Moody Aldrich Partners LLC39,237$2.36M0.48%+39,237New
Credit Suisse AG38,887$2.34M0.00%+7,609+24.3%Added
Voya Investment Management LLC38,000$2.29M0.00%+10,610+38.7%Added
State of New Jersey Common Pension Fund D37,600$2.27M0.01%+37,600New
New York State Common Retirement Fund35,780$2.16M0.00%−611−1.7%Reduced
Monarch Partners Asset Management LLC35,645$2.15M0.63%+2,285+6.8%Added
State of Wisconsin Investment Board32,995$1.99M0.01%−16,315−33.1%Reduced
Alps Advisors Inc32,776$1.97M0.02%+7,186+28.1%Added
Trexquant Investment LP31,237$1.88M0.05%+31,237New
Capital Fund Management S.A.29,772$1.79M0.04%+29,772New
Macquarie Group Ltd28,569$1.72M0.00%+27,702+3,195.2%Added
Schonfeld Strategic Advisors LLC28,128$1.69M0.01%−16,662−37.2%Reduced
Mariner, LLC26,927$1.62M0.01%+9,898+58.1%Added
D. E. Shaw & Co., Inc.26,856$1.62M0.00%−78,374−74.5%Reduced
BNP Paribas Arbitrage, SA25,411$1.53M0.00%−12,996−33.8%Reduced
Thornburg Investment Management Inc24,274$1.46M0.02%+24,274New
Ameriprise Financial Inc24,180$1.46M0.00%−10,153−29.6%Reduced
Edgewood Management LLC24,060$1.45M0.01%−940−3.8%Reduced
Man Group plc23,697$1.43M0.01%−27,019−53.3%Reduced
Deutsche Bank AG21,898$1.32M0.00%+5,619+34.5%Added
AXA S.A.19,852$1.20M0.00%−32,373−62.0%Reduced
MetLife Investment Management19,561$1.18M0.01%00.0%Unchanged
Algert Global LLC19,203$1.16M0.06%+10,533+121.5%Added
Prudential Financial Inc18,947$1.14M0.00%−20,932−52.5%Reduced
American International Group, Inc.17,344$1.04M0.01%+502+3.0%Added
Legal & General Group Plc17,034$1.03M0.00%+102+0.6%Added