Prothena Corp Public Ltd Co
PRTA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001559053
In the last 90 days, Prothena Corp Public Ltd Co insiders filed 4 open-market purchases and 2 sales; 187 institutions reported holding it in 13F filings for Q2 2026, worth $462.7M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Prothena Corp Public Ltd Co as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 182
- 0 vs. Q3 2025
- Shares held
- 47.3M
- +4.86M (+11.5%) vs. Q3 2025
- Total value
- $451.6M
- +$37.8M (+9.1%) vs. Q3 2025
- New holders
- 25
- 62 more added
- Sold out
- 25
- 57 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRTA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $462.7M |
| Q1 2026 | 186 | $459.5M |
| Q4 2025 | 182 | $451.6M |
| Q3 2025 | 187 | $415.8M |
| Q2 2025 | 189 | $253.6M |
| Q1 2025 | 161 | $647.2M |
| Q4 2024 | 171 | $741.3M |
| Q3 2024 | 164 | $855.8M |
| Q2 2024 | 160 | $1.05B |
| Q1 2024 | 169 | $1.33B |
| Q4 2023 | 187 | $1.95B |
| Q3 2023 | 187 | $2.56B |
| Q2 2023 | 196 | $3.54B |
| Q1 2023 | 192 | $2.51B |
| Q4 2022 | 201 | $2.98B |
| Q3 2022 | 183 | $2.69B |
| Q2 2022 | 167 | $1.21B |
| Q1 2022 | 174 | $1.61B |
| Q4 2021 | 196 | $2.12B |
| Q3 2021 | 192 | $2.92B |
| Q2 2021 | 156 | $2.08B |
| Q1 2021 | 146 | $1.00B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Prothena Corp Public Ltd Co; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| The PNC Financial Services Group, Inc. | 28,128 | $268.6K | 0.00% | +9,991+55.1% | Added |
| Persistent Asset Partners Ltd | 28,589 | $273.0K | 0.13% | +28,589 | New |
| RBF Capital, LLC | 29,200 | $278.9K | 0.01% | 00.0% | Unchanged |
| Profund Advisors LLC | 30,616 | $292.4K | 0.01% | +30,616 | New |
| Quadrature Capital Ltd | 31,090 | $296.9K | 0.00% | +3,875+14.2% | Added |
| Deutsche Bank AG | 35,482 | $338.9K | 0.00% | +1,709+5.1% | Added |
| DekaBank Deutsche Girozentrale | 14,000 | $383.0K | 0.00% | 00.0% | Unchanged |
| Public Employees Retirement System of Ohio | 42,158 | $402.6K | 0.00% | 00.0% | Unchanged |
| Seven Fleet Capital Management LP | 43,300 | $413.5K | 0.28% | +43,300 | New |
| Massachusetts Financial Services Co | 45,970 | $439.0K | 0.00% | −1,519−3.2% | Reduced |
| Franklin Resources Inc | 47,251 | $451.2K | 0.00% | −13,921−22.8% | Reduced |
| Quinn Opportunity Partners LLC | 50,000 | $477.5K | 0.02% | 00.0% | Unchanged |
| Marshall Wace, LLP | 54,778 | $523.1K | 0.00% | +54,778 | New |
| XTX Topco Ltd | 54,881 | $524.1K | 0.01% | +39,073+247.2% | Added |
| Rhumbline Advisers | 56,527 | $539.8K | 0.00% | −5,515−8.9% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 58,853 | $562.0K | 0.01% | +29,878+103.1% | Added |
| Wells Fargo & Company | 60,108 | $574.0K | 0.00% | +19,678+48.7% | Added |
| Caption Management, LLC | 61,009 | $582.6K | 0.03% | 00.0% | Unchanged |
| Creative Planning | 61,969 | $591.8K | 0.00% | −2,171−3.4% | Reduced |
| Pinnacle Associates Ltd | 62,724 | $599.0K | 0.01% | −8,537−12.0% | Reduced |
| SG Americas Securities, LLC | 63,018 | $602.0K | 0.00% | +6,299+11.1% | Added |
| Martingale Asset Management L P | 63,453 | $606.0K | 0.02% | +63,453 | New |
| Duncan Williams Asset Management, LLC | 70,281 | $624.8K | 0.16% | −18,058−20.4% | Reduced |
| Alliancebernstein L.P. | 69,607 | $664.7K | 0.00% | 00.0% | Unchanged |
| Assenagon Asset Management S.A. | 76,769 | $733.1K | 0.00% | −12,935−14.4% | Reduced |
| American Century Companies Inc | 78,804 | $752.6K | 0.00% | +6,565+9.1% | Added |
| Price T Rowe Associates Inc | 81,515 | $779.0K | 0.00% | +2,968+3.8% | Added |
| Rafferty Asset Management, LLC | 82,553 | $788.4K | 0.00% | +82,553 | New |
| ExodusPoint Capital Management, LP | 87,990 | $840.3K | 0.01% | +57,736+190.8% | Added |
| Hennion & Walsh Asset Management, Inc. | 91,284 | $871.8K | 0.03% | +6,686+7.9% | Added |
| Campbell & CO Investment Adviser LLC | 94,155 | $899.2K | 0.04% | +94,155 | New |
| Russell Investments Group, Ltd. | 99,350 | $948.8K | 0.00% | −28,407−22.2% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 100,510 | $959.9K | 0.02% | +88,339+725.8% | Added |
| Quantinno Capital Management LP | 103,618 | $989.6K | 0.00% | +2,431+2.4% | Added |
| Los Angeles Capital Management LLC | 95,406 | $999.9K | 0.00% | −24,018−20.1% | Reduced |
| Ameriprise Financial Inc | 105,441 | $1.01M | 0.00% | −95−0.1% | Reduced |
| Diadema Partners LP | 106,539 | $1.02M | 0.61% | +106,539 | New |
| Focused Wealth Management, Inc | 107,479 | $1.03M | 0.11% | +50,350+88.1% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 125,890 | $1.20M | 0.00% | +125,890 | New |
| Bank of New York Mellon Corp | 132,700 | $1.27M | 0.00% | −21,100−13.7% | Reduced |
| Walleye Capital LLC | 156,035 | $1.49M | 0.01% | +155,972+247,574.6% | Added |
| JPMorgan Chase & Co | 169,955 | $1.62M | 0.00% | −565,810−76.9% | Reduced |
| Barclays PLC | 183,625 | $1.75M | 0.00% | +85,550+87.2% | Added |
| AQR Capital Management LLC | 186,785 | $1.78M | 0.00% | −27,757−12.9% | Reduced |
| DCF Advisers, LLC | 195,747 | $1.87M | 0.62% | −5,000−2.5% | Reduced |
| Squarepoint Ops LLC | 218,041 | $2.08M | 0.00% | +91,008+71.6% | Added |
| Jump Financial, LLC | 237,828 | $2.27M | 0.03% | +51,581+27.7% | Added |
| Monimus Capital Management, LP | 254,122 | $2.43M | 1.60% | −3,934−1.5% | Reduced |
| Man Group plc | 269,513 | $2.57M | 0.00% | +137,540+104.2% | Added |
| Arrowstreet Capital, Limited Partnership | 298,101 | $2.85M | 0.00% | −356,193−54.4% | Reduced |
| Charles Schwab Investment Management Inc | 357,335 | $3.41M | 0.00% | +6,514+1.9% | Added |
| Northern Trust Corp | 363,241 | $3.47M | 0.00% | +28,584+8.5% | Added |
| Qube Research & Technologies Ltd | 407,689 | $3.89M | 0.01% | +153,444+60.4% | Added |
| BNP Paribas Arbitrage, SA | 423,955 | $4.05M | 0.00% | +195,945+85.9% | Added |
| UBS Group AG | 426,360 | $4.07M | 0.00% | +25,513+6.4% | Added |
| Bank of America Corp | 427,360 | $4.08M | 0.00% | +150,264+54.2% | Added |
| Two Sigma Advisers, LP | 427,400 | $4.08M | 0.01% | +161,700+60.9% | Added |
| Jane Street Group, LLC | 428,651 | $4.09M | 0.00% | −191,141−30.8% | Reduced |
| Renaissance Technologies LLC | 435,515 | $4.16M | 0.01% | +64,215+17.3% | Added |
| Birchview Capital, LP | 441,019 | $4.21M | 2.47% | −108,000−19.7% | Reduced |
| Rangeley Capital, LLC | 524,600 | $5.01M | 4.32% | −35,857−6.4% | Reduced |
| Mariner, LLC | 577,938 | $5.52M | 0.01% | −12,959−2.2% | Reduced |
| Two Sigma Investments, LP | 670,138 | $6.40M | 0.01% | +243,533+57.1% | Added |
| Nuveen, LLC | 759,107 | $7.25M | 0.00% | +90,817+13.6% | Added |
| Dimensional Fund Advisors LP | 775,207 | $7.40M | 0.00% | −31,781−3.9% | Reduced |
| Point72 Asset Management, L.P. | 860,018 | $8.21M | 0.01% | +213,272+33.0% | Added |
| Citadel Advisors LLC | 912,382 | $8.71M | 0.01% | +145,277+18.9% | Added |
| Goldman Sachs Group Inc | 935,333 | $8.93M | 0.00% | +582,112+164.8% | Added |
| Federated Hermes, Inc. | 974,367 | $9.31M | 0.02% | +281,549+40.6% | Added |
| Jacobs Levy Equity Management, Inc | 978,011 | $9.34M | 0.04% | +101,483+11.6% | Added |
| Geode Capital Management, LLC | 1,063,069 | $10.2M | 0.00% | +43,586+4.3% | Added |
| Morgan Stanley | 1,246,775 | $11.9M | 0.00% | +447,101+55.9% | Added |
| Palo Alto Investors LP | 1,320,510 | $12.6M | 1.76% | −3,518−0.3% | Reduced |
| Acadian Asset Management LLC | 1,437,358 | $13.7M | 0.02% | +198,116+16.0% | Added |
| ADAR1 Capital Management, LLC | 1,457,764 | $13.9M | 1.04% | −11,334−0.8% | Reduced |
| Armistice Capital, LLC | 1,500,000 | $14.3M | 0.35% | −324,000−17.8% | Reduced |
| D. E. Shaw & Co., Inc. | 1,681,369 | $16.1M | 0.01% | +365,951+27.8% | Added |
| Vanguard Group Inc | 2,140,909 | $20.4M | 0.00% | +91,060+4.4% | Added |
| State Street Corp | 2,267,802 | $21.7M | 0.00% | +1,366,764+151.7% | Added |
| Rubric Capital Management LP | 3,677,331 | $35.1M | 0.42% | +2,136,958+138.7% | Added |
| BlackRock, Inc. | 4,107,459 | $39.2M | 0.00% | +509,042+14.1% | Added |
| FMR LLC | 7,551,218 | $72.1M | 0.00% | −350,000−4.4% | Reduced |
| Algert Global LLC | 0 | $0 | 0.00% | −445,811−100.0% | Sold out |
| Janney Montgomery Scott LLC | 0 | $0 | 0.00% | −106,898−100.0% | Sold out |
| Monaco Asset Management SAM | 0 | $0 | 0.00% | −70,000−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −56,080−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −55,764−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −31,106−100.0% | Sold out |
| Proficio Capital Partners LLC | 0 | $0 | 0.00% | −30,136−100.0% | Sold out |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −30,000−100.0% | Sold out |
| Arizona PSPRS Trust | 0 | $0 | 0.00% | −27,700−100.0% | Sold out |
| Sandia Investment Management LP | 0 | $0 | 0.00% | −29,950−100.0% | Sold out |
| Cambridge Investment Research Advisors, Inc. | 0 | $0 | 0.00% | −27,513−100.0% | Sold out |
| Alps Advisors Inc | 0 | $0 | 0.00% | −25,727−100.0% | Sold out |
| Rock Springs Capital Management LP | 0 | $0 | 0.00% | −25,398−100.0% | Sold out |
| Handelsbanken Fonder AB | 0 | $0 | 0.00% | −20,900−100.0% | Sold out |
| Prosight Management, LP | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Foundation Wealth Management, LLC | 0 | $0 | 0.00% | −19,471−100.0% | Sold out |
| Thrivent Financial for Lutherans | 0 | $0 | 0.00% | −12,980−100.0% | Sold out |
| Jain Global LLC | 0 | $0 | 0.00% | −11,780−100.0% | Sold out |