Madrigal Pharmaceuticals, Inc.
MDGL- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001157601
In the last 90 days, Madrigal Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 3 sales; 414 institutions reported holding it in 13F filings for Q2 2026, worth $12.7B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Madrigal Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 352
- +51 vs. Q2 2025
- Shares held
- 23.4M
- +16.4K (+0.1%) vs. Q2 2025
- Total value
- $10.7B
- +$3.65B (+51.6%) vs. Q2 2025
- New holders
- 87
- 107 more added
- Sold out
- 36
- 107 more reduced
4 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MDGL on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 414 | $12.7B |
| Q1 2026 | 380 | $12.4B |
| Q4 2025 | 387 | $13.7B |
| Q3 2025 | 352 | $10.7B |
| Q2 2025 | 305 | $7.13B |
| Q1 2025 | 321 | $7.85B |
| Q4 2024 | 283 | $7.08B |
| Q3 2024 | 257 | $4.77B |
| Q2 2024 | 257 | $6.41B |
| Q1 2024 | 266 | $5.64B |
| Q4 2023 | 226 | $4.57B |
| Q3 2023 | 206 | $2.54B |
| Q2 2023 | 208 | $3.43B |
| Q1 2023 | 223 | $3.36B |
| Q4 2022 | 189 | $3.86B |
| Q3 2022 | 135 | $763.2M |
| Q2 2022 | 138 | $857.7M |
| Q1 2022 | 140 | $1.20B |
| Q4 2021 | 144 | $1.01B |
| Q3 2021 | 133 | $876.5M |
| Q2 2021 | 151 | $1.09B |
| Q1 2021 | 137 | $1.43B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Madrigal Pharmaceuticals, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Tri Locum Partners LP | 67,706 | $31.1M | 7.14% | −30,059−30.7% | Reduced |
| Soleus Capital Management, L.P. | 68,336 | $31.3M | 1.68% | +60,336+754.2% | Added |
| New York State Common Retirement Fund | 69,273 | $31.8M | 0.04% | +8,211+13.4% | Added |
| Raymond James Financial Inc | 70,584 | $32.4M | 0.01% | +15,651+28.5% | Added |
| BNP Paribas Arbitrage, SA | 70,757 | $32.5M | 0.03% | +1,720+2.5% | Added |
| Nuveen, LLC | 73,715 | $33.8M | 0.01% | +32,182+77.5% | Added |
| EcoR1 Capital, LLC | 75,000 | $34.4M | 1.65% | 00.0% | Unchanged |
| Franklin Resources Inc | 75,570 | $34.7M | 0.01% | +14,855+24.5% | Added |
| Balyasny Asset Management LLC | 82,401 | $37.8M | 0.08% | +47,901+138.8% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 85,773 | $39.3M | 0.12% | −14,322−14.3% | Reduced |
| Adage Capital Partners GP, L.L.C. | 88,500 | $40.6M | 0.06% | −287,663−76.5% | Reduced |
| Jane Street Group, LLC | 95,734 | $43.9M | 0.05% | +95,734 | New |
| D. E. Shaw & Co., Inc. | 96,182 | $44.1M | 0.04% | −15,799−14.1% | Reduced |
| Bank of New York Mellon Corp | 97,779 | $44.8M | 0.01% | +8,836+9.9% | Added |
| MPM Oncology Impact Management LP | 100,415 | $46.1M | 7.54% | 00.0% | Unchanged |
| Lord, Abbett & Co. LLC | 102,143 | $46.8M | 0.14% | +17,926+21.3% | Added |
| Woodline Partners LP | 103,847 | $47.6M | 0.22% | −55,776−34.9% | Reduced |
| Susquehanna International Group, LLP | 104,818 | $48.1M | 0.07% | +4,496+4.5% | Added |
| Affinity Asset Advisors, LLC | 115,000 | $52.7M | 4.91% | +35,000+43.8% | Added |
| Driehaus Capital Management LLC | 115,974 | $53.2M | 0.38% | +115,974 | New |
| Armistice Capital, LLC | 119,982 | $55.0M | 1.73% | −4,018−3.2% | Reduced |
| Alkeon Capital Management LLC | 120,000 | $55.0M | 0.25% | +120,000 | New |
| Renaissance Technologies LLC | 120,682 | $55.4M | 0.07% | +109,846+1,013.7% | Added |
| ArrowMark Colorado Holdings LLC | 123,259 | $56.5M | 1.05% | −21,549−14.9% | Reduced |
| Fiera Capital Corp | 127,800 | $58.6M | 0.19% | −2,822−2.2% | Reduced |
| Rock Springs Capital Management LP | 137,746 | $63.2M | 3.69% | −2,550−1.8% | Reduced |
| Northern Trust Corp | 159,988 | $73.4M | 0.01% | +17,120+12.0% | Added |
| American Century Companies Inc | 165,615 | $76.0M | 0.04% | −2,169−1.3% | Reduced |
| Pictet Asset Management Holding SA | 191,796 | $87.7M | 0.08% | −16,470−7.9% | Reduced |
| Erste Asset Management GmbH | 201,100 | $89.1M | 0.86% | 00.0% | Unchanged |
| Artisan Partners Limited Partnership | 206,254 | $94.6M | 0.14% | +4,683+2.3% | Added |
| Charles Schwab Investment Management Inc | 213,652 | $98.0M | 0.02% | +60,567+39.6% | Added |
| UBS Group AG | 217,343 | $99.7M | 0.02% | −288,371−57.0% | Reduced |
| Hood River Capital Management LLC | 242,808 | $111.4M | 1.31% | −1,930−0.8% | Reduced |
| Bank of America Corp | 244,292 | $112.0M | 0.01% | −32,929−11.9% | Reduced |
| Morgan Stanley | 249,647 | $114.5M | 0.01% | +1,685+0.7% | Added |
| Polar Capital Holdings Plc | 265,154 | $121.6M | 0.59% | +39,744+17.6% | Added |
| Invesco Ltd. | 299,565 | $137.4M | 0.02% | +99,209+49.5% | Added |
| Price T Rowe Associates Inc | 352,520 | $161.7M | 0.02% | −155,944−30.7% | Reduced |
| Goldman Sachs Group Inc | 386,100 | $177.1M | 0.03% | +196,260+103.4% | Added |
| FMR LLC | 401,136 | $184.0M | 0.01% | −44,203−9.9% | Reduced |
| Wellington Management Group LLP | 404,455 | $185.5M | 0.03% | +397,076+5,381.2% | Added |
| William Blair Investment Management, LLC | 411,802 | $188.9M | 0.49% | +61,513+17.6% | Added |
| Geode Capital Management, LLC | 446,233 | $204.7M | 0.01% | +31,841+7.7% | Added |
| State Street Corp | 658,097 | $301.8M | 0.01% | −32,618−4.7% | Reduced |
| BlackRock, Inc. | 1,559,712 | $715.4M | 0.01% | +120,988+8.4% | Added |
| Vanguard Group Inc | 1,812,054 | $831.1M | 0.01% | −65,227−3.5% | Reduced |
| Avoro Capital Advisors LLC | 1,833,000 | $840.7M | 10.88% | −42,000−2.2% | Reduced |
| Janus Henderson Group PLC | 1,842,690 | $845.3M | 0.39% | −349,063−15.9% | Reduced |
| Paulson & Co. Inc. | 1,907,523 | $874.9M | 29.46% | −182,000−8.7% | Reduced |
| RTW Investments, LP | 1,993,687 | $914.4M | 11.27% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 2,141,701 | $982.3M | 7.10% | +165,683+8.4% | Added |
| Braidwell LP | 0 | $0 | 0.00% | −60,781−100.0% | Sold out |
| Logos Global Management LP | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| 683 Capital Management, LLC | 0 | $0 | 0.00% | −24,865−100.0% | Sold out |
| Avidity Partners Management LP | 0 | $0 | 0.00% | −19,000−100.0% | Sold out |
| Kornitzer Capital Management Inc | 0 | $0 | 0.00% | −14,760−100.0% | Sold out |
| Magnetar Financial LLC | 0 | $0 | 0.00% | −6,730−100.0% | Sold out |
| Sivik Global Healthcare LLC | 0 | $0 | 0.00% | −5,000−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −4,518−100.0% | Sold out |
| Cavalier Investments, LLC | 0 | $0 | 0.00% | −3,710−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −2,878−100.0% | Sold out |
| Illinois Municipal Retirement Fund | 0 | $0 | 0.00% | −2,509−100.0% | Sold out |
| American Assets Investment Management, LLC | 0 | $0 | 0.00% | −2,000−100.0% | Sold out |
| Marex Group plc | 0 | $0 | 0.00% | −1,811−100.0% | Sold out |
| Qsemble Capital Management, LP | 0 | $0 | 0.00% | −1,513−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −1,415−100.0% | Sold out |
| LMR Partners LLP | 0 | $0 | 0.00% | −1,242−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −1,238−100.0% | Sold out |
| Rossby Financial, LCC | 0 | $0 | 0.00% | −1,048−100.0% | Sold out |
| HSBC Holdings PLC | 0 | $0 | 0.00% | −1,014−100.0% | Sold out |
| Overbrook Management Corp | 0 | $0 | 0.00% | −855−100.0% | Sold out |
| Garda Capital Partners LP | 0 | $0 | 0.00% | −702−100.0% | Sold out |
| Corton Capital Inc. | 0 | $0 | 0.00% | −695−100.0% | Sold out |
| Twin Tree Management, LP | 0 | $0 | 0.00% | −336−100.0% | Sold out |
| Mount Yale Investment Advisors, LLC | 0 | $0 | 0.00% | −311−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −288−100.0% | Sold out |
| VSM Wealth Advisory, LLC | 0 | $0 | 0.00% | −280−100.0% | Sold out |
| Lazard Asset Management LLC | 0 | $0 | 0.00% | −256−100.0% | Sold out |
| AdvisorNet Financial, Inc | 0 | $0 | 0.00% | −24−100.0% | Sold out |
| Clearstead Advisors, LLC | 0 | $0 | 0.00% | −14−100.0% | Sold out |
| ZRC Wealth Management, LLC | 0 | $0 | 0.00% | −9−100.0% | Sold out |
| CBIZ Investment Advisory Services, LLC | 0 | $0 | 0.00% | −8−100.0% | Sold out |
| Twin Peaks Wealth Advisors, LLC | 0 | $0 | 0.00% | −5−100.0% | Sold out |
| Bokf, NA | 0 | $0 | 0.00% | −3−100.0% | Sold out |
| N.E.W. Advisory Services LLC | 0 | $0 | 0.00% | −3−100.0% | Sold out |
| Stephens Consulting, LLC | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| Ronald Blue Trust, Inc. | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Norges Bank | – | – | – | – | Not filed |
| E Fund Management Co., Ltd. | – | – | – | – | Not filed |
| CIBC World Markets Corp | – | – | – | – | Not filed |
| First Horizon Advisors, Inc. | – | – | – | – | Not filed |