Lexeo Therapeutics, Inc.
LXEO- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001907108
In the last 90 days, Lexeo Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 141 institutions reported holding it in 13F filings for Q2 2026, worth $410.9M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Lexeo Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 146
- +38 vs. Q3 2025
- Shares held
- 76.5M
- +27.1M (+55.0%) vs. Q3 2025
- Total value
- $759.2M
- +$431.7M (+131.8%) vs. Q3 2025
- New holders
- 47
- 61 more added
- Sold out
- 9
- 26 more reduced
1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXEO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 141 | $410.9M |
| Q1 2026 | 139 | $458.7M |
| Q4 2025 | 146 | $759.2M |
| Q3 2025 | 109 | $327.5M |
| Q2 2025 | 90 | $169.9M |
| Q1 2025 | 88 | $100.0M |
| Q4 2024 | 90 | $194.2M |
| Q3 2024 | 69 | $268.8M |
| Q2 2024 | 60 | $426.3M |
| Q1 2024 | 54 | $361.5M |
| Q4 2023 | 31 | $217.1M |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Lexeo Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Bank of New York Mellon Corp | 166,749 | $1.66M | 0.00% | +95,072+132.6% | Added |
| Spruce Street Capital LP | 175,000 | $1.74M | 0.57% | +175,000 | New |
| Barclays PLC | 188,754 | $1.87M | 0.00% | +77,175+69.2% | Added |
| Charles Schwab Investment Management Inc | 192,210 | $1.91M | 0.00% | +86,450+81.7% | Added |
| Privium Fund Management B.V. | 192,550 | $1.91M | 0.35% | +194+0.1% | Added |
| Nuveen, LLC | 211,529 | $2.10M | 0.00% | +178,427+539.0% | Added |
| Renaissance Technologies LLC | 217,772 | $2.16M | 0.00% | +68,472+45.9% | Added |
| Y-Intercept (Hong Kong) Ltd | 231,163 | $2.30M | 0.05% | +231,163 | New |
| Ameriprise Financial Inc | 243,294 | $2.42M | 0.00% | +76,756+46.1% | Added |
| BNP Paribas Arbitrage, SA | 257,417 | $2.56M | 0.00% | +226,690+737.8% | Added |
| UBS Group AG | 281,083 | $2.79M | 0.00% | +31,174+12.5% | Added |
| AQR Capital Management LLC | 337,386 | $3.35M | 0.00% | −10,537−3.0% | Reduced |
| DAFNA Capital Management LLC | 340,859 | $3.38M | 0.79% | −17,224−4.8% | Reduced |
| Two Sigma Investments, LP | 400,567 | $3.98M | 0.01% | +315,804+372.6% | Added |
| Verition Fund Management LLC | 428,458 | $4.25M | 0.02% | +13,595+3.3% | Added |
| Northern Trust Corp | 457,052 | $4.54M | 0.00% | +220,599+93.3% | Added |
| Invesco Ltd. | 463,029 | $4.60M | 0.00% | +463,029 | New |
| D. E. Shaw & Co., Inc. | 480,205 | $4.77M | 0.00% | +467,387+3,646.3% | Added |
| Ikarian Capital, LLC | 513,011 | $5.09M | 0.66% | −54,590−9.6% | Reduced |
| Silverarc Capital Management, LLC | 617,608 | $6.13M | 0.89% | −161,003−20.7% | Reduced |
| Siren, L.L.C. | 720,622 | $7.16M | 0.21% | +117,187+19.4% | Added |
| Goldman Sachs Group Inc | 781,855 | $7.76M | 0.00% | +639,453+449.0% | Added |
| Dimensional Fund Advisors LP | 862,892 | $8.57M | 0.00% | −49,641−5.4% | Reduced |
| Blackstone Group Inc. | 904,959 | $8.99M | 0.04% | −219,963−19.6% | Reduced |
| Millennium Management LLC | 908,024 | $9.02M | 0.01% | −1,405,618−60.8% | Reduced |
| Nantahala Capital Management, LLC | 1,000,000 | $9.93M | 0.59% | +1,000,000 | New |
| 683 Capital Management, LLC | 1,120,000 | $11.1M | 0.92% | +197,338+21.4% | Added |
| Suvretta Capital Management, LLC | 1,250,000 | $12.4M | 0.31% | +1,250,000 | New |
| ADAR1 Capital Management, LLC | 1,393,161 | $13.8M | 1.03% | −138,792−9.1% | Reduced |
| Geode Capital Management, LLC | 1,445,887 | $14.4M | 0.00% | +724,006+100.3% | Added |
| Balyasny Asset Management LLC | 1,635,026 | $16.2M | 0.03% | −2,278,762−58.2% | Reduced |
| Octagon Capital Advisors LP | 1,725,000 | $17.1M | 2.14% | +1,725,000 | New |
| Point72 Asset Management, L.P. | 1,894,722 | $18.8M | 0.03% | −47,127−2.4% | Reduced |
| OrbiMed Advisors LLC | 2,125,000 | $21.1M | 0.43% | +2,125,000 | New |
| State Street Corp | 3,187,722 | $31.7M | 0.00% | +2,642,877+485.1% | Added |
| Woodline Partners LP | 3,197,760 | $31.8M | 0.12% | +625,598+24.3% | Added |
| Affinity Asset Advisors, LLC | 3,200,000 | $31.8M | 2.28% | −670,527−17.3% | Reduced |
| Avoro Capital Advisors LLC | 3,300,000 | $32.8M | 0.32% | +3,300,000 | New |
| Citadel Advisors LLC | 3,774,317 | $37.5M | 0.03% | +55,274+1.5% | Added |
| Vanguard Group Inc | 3,894,310 | $38.7M | 0.00% | +1,668,020+74.9% | Added |
| Frazier Life Sciences Management, L.P. | 4,424,725 | $43.9M | 1.18% | 00.0% | Unchanged |
| Vestal Point Capital, LP | 4,475,000 | $44.4M | 1.63% | +1,225,000+37.7% | Added |
| Paradigm Biocapital Advisors LP | 4,763,198 | $47.3M | 1.27% | +4,763,198 | New |
| BlackRock, Inc. | 4,907,563 | $48.7M | 0.00% | +2,736,471+126.0% | Added |
| Ra Capital Management, L.P. | 5,000,000 | $49.6M | 0.51% | +5,000,000 | New |
| Janus Henderson Group PLC | 5,509,635 | $54.7M | 0.02% | −595,892−9.8% | Reduced |
| D1 Capital Partners L.P.SuperinvestorD1 Capital Partners | 0 | $0 | 0.00% | −978,652−100.0% | Sold out |
| Palumbo Wealth Management LLC | 0 | $0 | 0.00% | −61,276−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −43,269−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −27,380−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −21,510−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −18,400−100.0% | Sold out |
| Axq Capital, LP | 0 | $0 | 0.00% | −14,921−100.0% | Sold out |
| Scientech Research LLC | 0 | $0 | 0.00% | −13,502−100.0% | Sold out |
| SRS Capital Advisors, Inc. | 0 | $0 | 0.00% | −4,551−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | – | – | – | – | Not filed |