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Lexeo Therapeutics, Inc.

LXEO
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001907108

In the last 90 days, Lexeo Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 141 institutions reported holding it in 13F filings for Q2 2026, worth $410.9M in total; no superinvestor holds it.

Q4 2025 vs. Q3 2025

How the institutions holding Lexeo Therapeutics, Inc. changed between Q3 2025 and Q4 2025.

All holders in Q4 2025All holders in Q3 2025

13F holders of LXEO: Q3 2025 compared with Q4 2025
MeasureQ3 2025Of which not filed for Q4 2025Q4 2025Change
Holders1091146+38
Shares49.3M2.51K76.5M+27.1M (+55.0%)
Value$327.5M$16.6K$759.2M+$431.7M (+131.8%)

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (47)

Institutions that held Lexeo Therapeutics, Inc. at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to LXEO in Q4 2025
InstitutionSharesValue% of portfolio
Ra Capital Management, L.P.5,000,000$49.6M0.51%
Paradigm Biocapital Advisors LP4,763,198$47.3M1.27%
Avoro Capital Advisors LLC3,300,000$32.8M0.32%
OrbiMed Advisors LLC2,125,000$21.1M0.43%
Octagon Capital Advisors LP1,725,000$17.1M2.14%
Suvretta Capital Management, LLC1,250,000$12.4M0.31%
Nantahala Capital Management, LLC1,000,000$9.93M0.59%
Invesco Ltd.463,029$4.60M0.00%
Y-Intercept (Hong Kong) Ltd231,163$2.30M0.05%
Spruce Street Capital LP175,000$1.74M0.57%
Qube Research & Technologies Ltd133,257$1.32M0.00%
Burkehill Global Management, LP125,000$1.24M0.08%
Rafferty Asset Management, LLC102,159$1.01M0.00%
Squarepoint Ops LLC92,608$919.6K0.00%
Wellington Management Group LLP83,230$826.5K0.00%
Two Sigma Advisers, LP81,300$807.3K0.00%
Atom Investors LP68,491$680.1K0.05%
Acadian Asset Management LLC50,909$505.0K0.00%
Profund Advisors LLC38,054$377.9K0.01%
MetLife Investment Management35,721$354.7K0.00%
Graham Capital Management, L.P.32,898$326.7K0.01%
Virtus Investment Advisers, Inc.27,230$270.4K0.07%
Winton Group Ltd26,900$267.1K0.01%
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.26,209$251.9K0.00%
Omers Administration Corp20,900$207.5K0.00%
Manufacturers Life Insurance Company, The19,147$190.1K0.00%
SG Americas Securities, LLC18,640$185.0K0.00%
Persistent Asset Partners Ltd16,025$159.1K0.08%
ProShare Advisors LLC14,752$146.5K0.00%
Raymond James Financial Inc12,538$124.5K0.00%
Quest Partners LLC11,726$116.4K0.01%
Gsa Capital Partners LLP11,463$114.0K0.01%
Voya Investment Management LLC10,976$109.0K0.00%
Creative Planning10,358$102.9K0.00%
Caitong International Asset Management Co., Ltd3,714$36.9K0.01%
Bessemer Group Inc2,380$24.0K0.00%
Group One Trading, L.P.1,816$18.0K0.00%
Aquatic Capital Management LLC1,085$10.8K0.00%
US Bancorp555$5.51K0.00%
Torren Management, LLC321$3.19K0.00%
Daiwa Securities Group Inc.243$2.00K0.00%
Basecamp Wealth Advisors LLC113$1.12K0.00%
Farther Finance Advisors, LLC57$5660.00%
Rialto Wealth Management, LLC53$5270.00%
GAMMA Investing LLC50$4970.00%
Smartleaf Asset Management LLC4$390.00%
Rothschild Investment LLC1$100.00%

Sold out (9)

Institutions that held Lexeo Therapeutics, Inc. at the end of Q3 2025 and filed for Q4 2025 without it.

Institutions that sold out of LXEO in Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
D1 Capital Partners L.P.SuperinvestorD1 Capital Partners978,652$6.50M
Palumbo Wealth Management LLC61,276$406.9K
Virtu Financial LLC43,269$287.0K
ExodusPoint Capital Management, LP27,380$181.8K
HRT Financial LP21,510$142.0K
Brevan Howard Capital Management LP18,400$122.2K
Axq Capital, LP14,921$99.1K
Scientech Research LLC13,502$89.7K
SRS Capital Advisors, Inc.4,551$30.2K

Not filed for Q4 2025 yet (1)

Institutions that held Lexeo Therapeutics, Inc. at the end of Q3 2025 and haven't filed a 13F for Q4 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding LXEO in Q3 2025 that haven't filed for Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Cubist Systematic Strategies, LLC2,506$16.6K