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Lexeo Therapeutics, Inc.

LXEO
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001907108

In the last 90 days, Lexeo Therapeutics, Inc. insiders filed 0 open-market purchases and 7 sales; 141 institutions reported holding it in 13F filings for Q2 2026, worth $410.9M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Lexeo Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
109
+19 vs. Q2 2025
Shares held
49.3M
+7.08M (+16.8%) vs. Q2 2025
Total value
$327.5M
+$157.6M (+92.8%) vs. Q2 2025
New holders
26
50 more added
Sold out
7
15 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXEO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 109 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 31 institutionsQ1 2024: 54 institutionsQ2 2024: 60 institutionsQ3 2024: 69 institutionsQ4 2024: 90 institutionsQ1 2025: 88 institutionsQ2 2025: 90 institutionsQ3 2025: 109 institutionsQ4 2025: 146 institutionsQ1 2026: 139 institutionsQ2 2026: 141 institutions
Value heldQ3 2025: $327.5M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $217.1MQ1 2024: $361.5MQ2 2024: $426.3MQ3 2024: $268.8MQ4 2024: $194.2MQ1 2025: $100.0MQ2 2025: $169.9MQ3 2025: $327.5MQ4 2025: $759.2MQ1 2026: $458.7MQ2 2026: $410.9M
Institutions holding LXEO and their total value by quarter
QuarterHoldersValue
Q2 2026141$410.9M
Q1 2026139$458.7M
Q4 2025146$759.2M
Q3 2025109$327.5M
Q2 202590$169.9M
Q1 202588$100.0M
Q4 202490$194.2M
Q3 202469$268.8M
Q2 202460$426.3M
Q1 202454$361.5M
Q4 202331$217.1M
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Lexeo Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding LXEO in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Janus Henderson Group PLC6,105,527$40.5M0.02%+2,421,144+65.7%Added
Frazier Life Sciences Management, L.P.4,424,725$29.4M0.88%00.0%Unchanged
Balyasny Asset Management LLC3,913,788$26.0M0.05%−95,349−2.4%Reduced
Affinity Asset Advisors, LLC3,870,527$25.7M2.39%+281,172+7.8%Added
Citadel Advisors LLC3,719,043$24.7M0.02%+111,076+3.1%Added
Vestal Point Capital, LP3,250,000$21.6M0.98%+21,839+0.7%Added
Woodline Partners LP2,572,162$17.1M0.08%00.0%Unchanged
Millennium Management LLC2,313,642$15.4M0.01%−522,650−18.4%Reduced
Vanguard Group Inc2,226,290$14.8M0.00%+223,424+11.2%Added
BlackRock, Inc.2,171,092$14.4M0.00%+343,128+18.8%Added
Point72 Asset Management, L.P.1,941,849$12.9M0.03%+1,293,969+199.7%Added
ADAR1 Capital Management, LLC1,531,953$10.2M1.01%+1,386,844+955.7%Added
Blackstone Group Inc.1,124,922$7.47M0.03%00.0%Unchanged
D1 Capital Partners L.P.SuperinvestorD1 Capital Partners978,652$6.50M0.07%00.0%Unchanged
683 Capital Management, LLC922,662$6.13M0.56%+922,662New
Dimensional Fund Advisors LP912,533$6.06M0.00%+865,510+1,840.6%Added
Silverarc Capital Management, LLC778,611$5.17M0.75%+778,611New
Geode Capital Management, LLC721,881$4.79M0.00%+143,800+24.9%Added
Siren, L.L.C.603,435$4.01M0.16%00.0%Unchanged
Ikarian Capital, LLC567,601$3.77M0.85%+17,572+3.2%Added
State Street Corp544,845$3.62M0.00%+31,819+6.2%Added
Verition Fund Management LLC414,863$2.75M0.02%00.0%Unchanged
DAFNA Capital Management LLC358,083$2.38M0.59%−20,000−5.3%Reduced
AQR Capital Management LLC347,923$2.31M0.00%+159,288+84.4%Added
UBS Group AG249,909$1.66M0.00%−21,995−8.1%Reduced
Northern Trust Corp236,453$1.57M0.00%+35,667+17.8%Added
Privium Fund Management B.V.192,356$1.28M0.23%+14,000+7.8%Added
Boothbay Fund Management, LLC180,744$1.20M0.03%+17,572+10.8%Added
Ameriprise Financial Inc166,538$1.11M0.00%+166,538New
Renaissance Technologies LLC149,300$991.4K0.00%+43,100+40.6%Added
Goldman Sachs Group Inc142,402$945.5K0.00%+106,034+291.6%Added
Perceptive Advisors LLC139,835$928.5K0.03%00.0%Unchanged
Jane Street Group, LLC129,472$859.7K0.00%+129,472New
Barclays PLC111,579$740.9K0.00%−4,563−3.9%Reduced
Charles Schwab Investment Management Inc105,760$702.2K0.00%+41,540+64.7%Added
Morgan Stanley98,057$651.1K0.00%+13,276+15.7%Added
Two Sigma Investments, LP84,763$562.8K0.00%+15,521+22.4%Added
Bank of New York Mellon Corp71,677$475.9K0.00%+6,525+10.0%Added
Palumbo Wealth Management LLC61,276$406.9K0.13%+4,973+8.8%Added
Bridgeway Capital Management, LLC48,400$321.4K0.01%−5,000−9.4%Reduced
Virtu Financial LLC43,269$287.0K0.02%+43,269New
American Century Companies Inc36,154$240.1K0.00%+36,154New
Panagora Asset Management Inc34,297$227.7K0.00%−444−1.3%Reduced
Pale Fire Capital SE33,650$223.4K0.02%+6,000+21.7%Added
Ieq Capital, LLC33,581$223.0K0.00%+21,730+183.4%Added
Nuveen, LLC33,102$219.8K0.00%00.0%Unchanged
Rhumbline Advisers31,764$210.9K0.00%−226−0.7%Reduced
BNP Paribas Arbitrage, SA30,727$204.0K0.00%−17,707−36.6%Reduced
Alliancebernstein L.P.29,370$195.0K0.00%00.0%Unchanged
Susquehanna International Group, LLP28,931$192.1K0.00%−19,080−39.7%Reduced
Bank of America Corp28,279$187.8K0.00%+1,626+6.1%Added
ExodusPoint Capital Management, LP27,380$181.8K0.00%+27,380New
XTX Topco Ltd26,715$177.4K0.01%+26,715New
Deutsche Bank AG24,322$161.5K0.00%+400+1.7%Added
Cerity Partners LLC23,590$156.6K0.00%+11,143+89.5%Added
Susquehanna Portfolio Strategies, LLC22,909$152.1K0.00%+650+2.9%Added
HRT Financial LP21,510$142.0K0.00%+21,510New
Soltis Investment Advisors LLC20,000$132.8K0.01%00.0%Unchanged
Wells Fargo & Company19,262$127.9K0.00%+3,937+25.7%Added
CWM, LLC18,864$125.0K0.00%+8,513+82.2%Added
Brevan Howard Capital Management LP18,400$122.2K0.00%+18,400New
Wealth Enhancement Advisory Services, LLC14,244$118.8K0.00%+14,244New
Caxton Corp17,332$115.1K0.50%00.0%Unchanged
JustInvest LLC16,595$110.2K0.00%+1,595+10.6%Added
Axq Capital, LP14,921$99.1K0.04%+2,446+19.6%Added
JPMorgan Chase & Co14,359$95.3K0.00%+609+4.4%Added
Scientech Research LLC13,502$89.7K0.03%+13,502New
FMR LLC13,433$89.2K0.00%+1,680+14.3%Added
D. E. Shaw & Co., Inc.12,818$85.1K0.00%+12,818New
Price T Rowe Associates Inc11,965$80.0K0.00%+1,540+14.8%Added
Intech Investment Management LLC11,871$78.8K0.00%−1,811−13.2%Reduced
Mirae Asset Global ETFs Holdings Ltd.11,453$76.0K0.00%−2,024−15.0%Reduced
Ethic Inc.11,319$75.2K0.00%+593+5.5%Added
Los Angeles Capital Management LLC11,075$73.5K0.00%+11,075New
Commonwealth Equity Services, LLC10,890$72.0K0.00%+700+6.9%Added
China Universal Asset Management Co., Ltd.9,466$62.9K0.01%+2,799+42.0%Added
Citigroup Inc7,432$49.3K0.00%−7,316−49.6%Reduced
Royal Bank of Canada6,849$46.0K0.00%+3,711+118.3%Added
Police & Firemen's Retirement System of New Jersey6,040$40.1K0.00%00.0%Unchanged
SRS Capital Advisors, Inc.4,551$30.2K0.00%+4,551New
New York State Common Retirement Fund4,187$27.8K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)3,737$24.8K0.00%−1,357−26.6%Reduced
Nisa Investment Advisors, LLC2,765$18.4K0.00%00.0%Unchanged
Cubist Systematic Strategies, LLC2,506$16.6K0.00%+2,506New
Ameritas Investment Partners, Inc.2,387$15.8K0.00%00.0%Unchanged
Russell Investments Group, Ltd.2,257$15.0K0.00%+2,038+930.6%Added
Mirae Asset Global Investments Co., Ltd.2,088$13.9K0.00%+806+62.9%Added
Legal & General Group Plc2,032$13.5K0.00%00.0%Unchanged
California State Teachers Retirement System1,736$11.5K0.00%+1+0.1%Added
Sterling Capital Management LLC1,733$11.5K0.00%+1,088+168.7%Added
GF Fund Management Co. Ltd.1,162$7.72K0.00%+342+41.7%Added
EverSource Wealth Advisors, LLC731$4.85K0.00%+74+11.3%Added
The PNC Financial Services Group, Inc.673$4.47K0.00%+673New
Amalgamated Bank623$4.00K0.00%00.0%Unchanged
Essential Partners LLC471$3.13K0.00%+297+170.7%Added
Simplex Trading, LLC499$3.00K0.00%+499New
Optiver Holding B.V.312$2.07K0.00%+312New
Allworth Financial LP307$2.04K0.00%+307New
Clearstead Advisors, LLC304$2.02K0.00%+304New
True Wealth Design, LLC226$1.50K0.00%+223+7,433.3%Added