Lexeo Therapeutics, Inc.
LXEO- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001907108
In the last 90 days, Lexeo Therapeutics, Inc. insiders filed 0 open-market purchases and 7 sales; 141 institutions reported holding it in 13F filings for Q2 2026, worth $410.9M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Lexeo Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 139
- −6 vs. Q4 2025
- Shares held
- 79.9M
- +7.32M (+10.1%) vs. Q4 2025
- Total value
- $458.7M
- −$261.8M (−36.3%) vs. Q4 2025
- New holders
- 21
- 58 more added
- Sold out
- 27
- 38 more reduced
1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXEO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 141 | $410.9M |
| Q1 2026 | 139 | $458.7M |
| Q4 2025 | 146 | $759.2M |
| Q3 2025 | 109 | $327.5M |
| Q2 2025 | 90 | $169.9M |
| Q1 2025 | 88 | $100.0M |
| Q4 2024 | 90 | $194.2M |
| Q3 2024 | 69 | $268.8M |
| Q2 2024 | 60 | $426.3M |
| Q1 2024 | 54 | $361.5M |
| Q4 2023 | 31 | $217.1M |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Lexeo Therapeutics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Paradigm Biocapital Advisors LP | 6,184,134 | $35.5M | 0.73% | +1,420,936+29.8% | Added |
| BlackRock, Inc. | 5,110,871 | $29.3M | 0.00% | +203,308+4.1% | Added |
| Affinity Asset Advisors, LLC | 5,050,211 | $29.0M | 1.70% | +1,850,211+57.8% | Added |
| Ra Capital Management, L.P. | 5,000,000 | $28.7M | 0.30% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 4,976,429 | $28.5M | 0.01% | −533,206−9.7% | Reduced |
| Vestal Point Capital, LP | 4,475,000 | $25.7M | 0.72% | 00.0% | Unchanged |
| Frazier Life Sciences Management, L.P. | 4,424,725 | $25.4M | 0.65% | 00.0% | Unchanged |
| Citadel Advisors LLC | 3,834,999 | $22.0M | 0.02% | +60,682+1.6% | Added |
| OrbiMed Advisors LLC | 3,602,450 | $20.7M | 0.47% | +1,477,450+69.5% | Added |
| State Street Corp | 3,568,242 | $20.5M | 0.00% | +380,520+11.9% | Added |
| Vanguard Capital Management LLC | 3,007,093 | $17.3M | 0.00% | +3,007,093 | New |
| Woodline Partners LP | 2,750,532 | $15.8M | 0.06% | −447,228−14.0% | Reduced |
| Goldman Sachs Group Inc | 1,949,885 | $11.2M | 0.00% | +1,168,030+149.4% | Added |
| Avoro Capital Advisors LLC | 1,875,000 | $10.8M | 0.11% | −1,425,000−43.2% | Reduced |
| Point72 Asset Management, L.P. | 1,680,449 | $9.65M | 0.02% | −214,273−11.3% | Reduced |
| Millennium Management LLC | 1,612,780 | $9.26M | 0.01% | +704,756+77.6% | Added |
| Balyasny Asset Management LLC | 1,589,585 | $9.12M | 0.02% | −45,441−2.8% | Reduced |
| Geode Capital Management, LLC | 1,513,777 | $8.69M | 0.00% | +67,890+4.7% | Added |
| ADAR1 Capital Management, LLC | 1,467,350 | $8.42M | 0.51% | +74,189+5.3% | Added |
| Suvretta Capital Management, LLC | 1,250,000 | $7.17M | 0.19% | 00.0% | Unchanged |
| 683 Capital Management, LLC | 1,200,000 | $6.89M | 0.64% | +80,000+7.1% | Added |
| Nantahala Capital Management, LLC | 1,200,000 | $6.89M | 0.43% | +200,000+20.0% | Added |
| Dimensional Fund Advisors LP | 1,103,584 | $6.33M | 0.00% | +240,692+27.9% | Added |
| Octagon Capital Advisors LP | 1,100,000 | $6.31M | 0.70% | −625,000−36.2% | Reduced |
| Spruce Street Capital LP | 928,593 | $5.33M | 1.28% | +753,593+430.6% | Added |
| Blackstone Group Inc. | 904,959 | $5.19M | 0.02% | 00.0% | Unchanged |
| Vanguard Portfolio Management LLC | 577,192 | $3.31M | 0.00% | +577,192 | New |
| Ikarian Capital, LLC | 513,011 | $2.94M | 0.42% | 00.0% | Unchanged |
| Northern Trust Corp | 493,666 | $2.83M | 0.00% | +36,614+8.0% | Added |
| Bank of America Corp | 491,532 | $2.82M | 0.00% | +331,244+206.7% | Added |
| Qube Research & Technologies Ltd | 465,515 | $2.67M | 0.00% | +332,258+249.3% | Added |
| Morgan Stanley | 402,924 | $2.31M | 0.00% | +262,743+187.4% | Added |
| Vanguard Fiduciary Trust Co | 384,734 | $2.21M | 0.00% | +384,734 | New |
| DAFNA Capital Management LLC | 377,059 | $2.16M | 0.49% | +36,200+10.6% | Added |
| AQR Capital Management LLC | 339,623 | $1.95M | 0.00% | +2,237+0.7% | Added |
| UBS Group AG | 321,737 | $1.85M | 0.00% | +40,654+14.5% | Added |
| Squarepoint Ops LLC | 319,090 | $1.83M | 0.00% | +226,482+244.6% | Added |
| Standard Life Aberdeen plc | 245,904 | $1.41M | 0.00% | +245,904 | New |
| BNP Paribas Arbitrage, SA | 228,201 | $1.31M | 0.00% | −29,216−11.3% | Reduced |
| Privium Fund Management B.V. | 205,000 | $1.18M | 0.24% | +12,450+6.5% | Added |
| Nuveen, LLC | 182,975 | $1.05M | 0.00% | −28,554−13.5% | Reduced |
| Charles Schwab Investment Management Inc | 182,069 | $1.05M | 0.00% | −10,141−5.3% | Reduced |
| Two Sigma Investments, LP | 181,676 | $1.04M | 0.00% | −218,891−54.6% | Reduced |
| Wellington Management Group LLP | 172,703 | $991.3K | 0.00% | +89,473+107.5% | Added |
| Bank of New York Mellon Corp | 158,899 | $912.1K | 0.00% | −7,850−4.7% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 142,571 | $818.4K | 0.02% | −88,592−38.3% | Reduced |
| Boothbay Fund Management, LLC | 136,377 | $782.8K | 0.02% | 00.0% | Unchanged |
| Burkehill Global Management, LP | 125,000 | $717.5K | 0.04% | 00.0% | Unchanged |
| Susquehanna Portfolio Strategies, LLC | 112,982 | $648.5K | 0.01% | +86,777+331.1% | Added |
| ExodusPoint Capital Management, LP | 112,172 | $643.9K | 0.01% | +112,172 | New |
| Alliancebernstein L.P. | 61,810 | $613.8K | 0.00% | 00.0% | Unchanged |
| Rafferty Asset Management, LLC | 100,896 | $579.1K | 0.00% | −1,263−1.2% | Reduced |
| XTX Topco Ltd | 100,607 | $577.5K | 0.01% | +89,463+802.8% | Added |
| JPMorgan Chase & Co | 93,163 | $491.0K | 0.00% | +63,302+212.0% | Added |
| Rhumbline Advisers | 72,082 | $413.7K | 0.00% | +2,713+3.9% | Added |
| Creative Planning | 67,079 | $385.0K | 0.00% | +56,721+547.6% | Added |
| Invesco Ltd. | 63,518 | $364.6K | 0.00% | −399,511−86.3% | Reduced |
| Deutsche Bank AG | 63,051 | $361.9K | 0.00% | +5,885+10.3% | Added |
| DRW Securities, LLC | 47,988 | $275.5K | 0.02% | +47,988 | New |
| Bleakley Financial Group, LLC | 47,964 | $275.3K | 0.00% | +47,964 | New |
| Susquehanna International Group, LLP | 46,998 | $269.8K | 0.00% | +9,989+27.0% | Added |
| Profund Advisors LLC | 45,161 | $259.2K | 0.01% | +7,107+18.7% | Added |
| Price T Rowe Associates Inc | 43,132 | $248.0K | 0.00% | +9,260+27.3% | Added |
| Vanguard Global Advisers, LLC | 42,575 | $244.4K | 0.00% | +42,575 | New |
| Los Angeles Capital Management LLC | 37,071 | $212.8K | 0.00% | +25,516+220.8% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 37,071 | $209.5K | 0.00% | +1,814+5.1% | Added |
| MetLife Investment Management | 35,584 | $204.3K | 0.00% | −137−0.4% | Reduced |
| Gsa Capital Partners LLP | 34,269 | $197.0K | 0.01% | +22,806+199.0% | Added |
| Panagora Asset Management Inc | 34,297 | $196.9K | 0.00% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 30,477 | $174.9K | 0.00% | −449,728−93.7% | Reduced |
| Virtus Investment Advisers, Inc. | 27,910 | $160.2K | 0.04% | +680+2.5% | Added |
| Axq Capital, LP | 26,119 | $149.9K | 0.02% | +26,119 | New |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 25,577 | $146.8K | 0.00% | −632−2.4% | Reduced |
| Wells Fargo & Company | 24,993 | $143.5K | 0.00% | −45,743−64.7% | Reduced |
| FMR LLC | 24,388 | $140.0K | 0.00% | +11,000+82.2% | Added |
| Schonfeld Strategic Advisors LLC | 24,221 | $139.0K | 0.00% | +24,221 | New |
| Cerity Partners LLC | 21,027 | $120.7K | 0.00% | −1,412−6.3% | Reduced |
| Soltis Investment Advisors LLC | 20,000 | $114.8K | 0.01% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 19,887 | $114.2K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 18,317 | $105.1K | 0.00% | −636−3.4% | Reduced |
| Manufacturers Life Insurance Company, The | 17,738 | $101.8K | 0.00% | −1,409−7.4% | Reduced |
| JustInvest LLC | 17,565 | $100.8K | 0.00% | +1,129+6.9% | Added |
| EntryPoint Capital, LLC | 16,560 | $95.1K | 0.03% | +16,560 | New |
| Intech Investment Management LLC | 16,504 | $94.7K | 0.00% | +2,316+16.3% | Added |
| Police & Firemen's Retirement System of New Jersey | 16,373 | $94.0K | 0.00% | 00.0% | Unchanged |
| Wealth Enhancement Advisory Services, LLC | 15,991 | $91.5K | 0.00% | +1,661+11.6% | Added |
| Raymond James Financial Inc | 15,585 | $89.5K | 0.00% | +3,047+24.3% | Added |
| Caxton Corp | 13,943 | $80.0K | 1.99% | 00.0% | Unchanged |
| Commonwealth Equity Services, LLC | 13,620 | $78.2K | 0.00% | +2,386+21.2% | Added |
| Bridgeway Capital Management, LLC | 13,400 | $76.9K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 13,320 | $76.5K | 0.00% | −1,973−12.9% | Reduced |
| China Universal Asset Management Co., Ltd. | 12,952 | $74.3K | 0.01% | +1,059+8.9% | Added |
| ProShare Advisors LLC | 12,852 | $73.8K | 0.00% | −1,900−12.9% | Reduced |
| E Fund Management Co., Ltd. | 12,683 | $72.8K | 0.00% | +12,683 | New |
| Barclays PLC | 12,165 | $69.8K | 0.00% | −176,589−93.6% | Reduced |
| Virtu Financial LLC | 11,901 | $68.0K | 0.00% | +11,901 | New |
| Ethic Inc. | 11,132 | $63.9K | 0.00% | −317−2.8% | Reduced |
| Voya Investment Management LLC | 10,705 | $61.4K | 0.00% | −271−2.5% | Reduced |
| Tower Research Capital LLC (TRC) | 9,485 | $54.4K | 0.00% | +8,659+1,048.3% | Added |
| Russell Investments Group, Ltd. | 6,639 | $38.1K | 0.00% | +767+13.1% | Added |