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Karyopharm Therapeutics Inc.

KPTI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001503802

In the last 90 days, Karyopharm Therapeutics Inc. insiders filed 0 open-market purchases and 3 sales; 96 institutions reported holding it in 13F filings for Q2 2026, worth $206.8M in total; no superinvestor holds it.

Q2 2021 vs. Q1 2021

How the institutions holding Karyopharm Therapeutics Inc. changed between Q1 2021 and Q2 2021.

All holders in Q2 2021All holders in Q1 2021

13F holders of KPTI: Q1 2021 compared with Q2 2021
MeasureQ1 2021Of which not filed for Q2 2021Q2 2021Change
Holders1711154−16
Shares60.2M11.3K59.0M−1.17M (−1.9%)
Value$637.1M$118.0K$608.7M−$28.3M (−4.4%)

1 institution that held it in Q1 2021 haven't filed for Q2 2021 yet. Not filing isn't selling, so the changes leave them out.

New holders (21)

Institutions that held Karyopharm Therapeutics Inc. at the end of Q2 2021 but not at the end of Q1 2021.

Institutions new to KPTI in Q2 2021
InstitutionSharesValue% of portfolio
Rubric Capital Management LP4,253,212$43.9M2.77%
Jacobs Levy Equity Management, Inc81,257$839.0K0.01%
M&G Investment Management Ltd62,183$622.0K0.00%
Algert Global LLC36,320$375.0K0.13%
Squarepoint Ops LLC34,409$355.0K0.00%
Virginia Retirement Systems Et Al23,500$243.0K0.00%
Boothbay Fund Management, LLC23,067$238.0K0.01%
Centiva Capital, LP20,405$211.0K0.02%
Renaissance Technologies LLC18,472$191.0K0.00%
State of Wyoming14,403$149.0K0.09%
ACT Capital Management, LLC14,000$145.0K0.07%
LPL Financial LLC10,558$109.0K0.00%
Cambridge Investment Research Advisors, Inc.10,431$108.0K0.00%
Altshuler Shaham Ltd9,739$101.0K0.00%
Tarbox Family Office, Inc.3,000$31.0K0.01%
American Portfolios Advisors1,000$10.3K0.00%
Founders Capital Management1,000$10.0K0.01%
Advisory Services Network, LLC900$9.00K0.00%
Lindbrook Capital, LLC575$6.00K0.00%
TCI Wealth Advisors, Inc.298$3.00K0.00%
Quadrant Capital Group LLC25$00.00%

Sold out (37)

Institutions that held Karyopharm Therapeutics Inc. at the end of Q1 2021 and filed for Q2 2021 without it.

Institutions that sold out of KPTI in Q2 2021
InstitutionShares, Q1 2021Value, Q1 2021
Adage Capital Partners GP, L.L.C.1,349,800$14.2M
Compagnie Lombard Odier SCmA829,681$8.73M
Schonfeld Strategic Advisors LLC178,704$1.88M
Junson Asset Management (Hong Kong) Ltd150,000$1.57M
Qube Research & Technologies Ltd146,442$1.54M
California Public Employees Retirement System143,000$1.50M
Phocas Financial Corp.135,816$1.43M
Knights of Columbus Asset Advisors LLC72,343$761.0K
PDT Partners, LLC71,026$747.0K
Seven Eight Capital, LP46,600$721.0K
Dynamic Technology Lab Private Ltd61,002$642.0K
First Trust Advisors LP58,053$611.0K
Teachers Retirement System of the State of Kentucky46,472$489.0K
Emerald Advisers, LLC46,470$489.0K
D.A. Davidson & Co.41,000$431.0K
Bridgefront Capital, LLC37,381$393.0K
Insight Advisors, LLC32,765$306.0K
Bayesian Capital Management, LP27,000$284.0K
AlphaCrest Capital Management LLC26,000$274.0K
Mesirow Financial Investment Management, Inc.21,712$228.0K
SG Americas Securities, LLC16,269$171.0K
Twinbeech Capital LP15,988$168.0K
D. E. Shaw & Co., Inc.14,865$156.0K
HSBC Holdings PLC14,239$149.0K
Man Group plc11,646$122.0K
Victory Capital Management Inc11,432$120.0K
Emerald Mutual Fund Advisers Trust11,145$117.0K
Private Advisor Group, LLC11,070$116.0K
CSS LLC10,127$106.0K
Pacer Advisors, Inc.6,328$67.0K
Valeo Financial Advisors, LLC2,107$22.0K
Sowell Financial Services LLC1,255$10.0K
Ikarian Capital, LLC791$9.00K
Point72 Hong Kong Ltd299$3.00K
International Assets Investment Management, LLC100$2.00K
Parallel Advisors, LLC102$1.00K
Certified Advisory Corp95$1.00K

Not filed for Q2 2021 yet (1)

Institutions that held Karyopharm Therapeutics Inc. at the end of Q1 2021 and haven't filed a 13F for Q2 2021. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding KPTI in Q1 2021 that haven't filed for Q2 2021
InstitutionShares, Q1 2021Value, Q1 2021
E Fund Management Co., Ltd.11,264$118.0K