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INSMED Inc

INSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001104506

In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q1 2026

Institutional positions in INSMED Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
675
+8 vs. Q4 2025
Shares held
220.9M
+27.6M (+14.3%) vs. Q4 2025
Total value
$35.7B
+$2.06B (+6.1%) vs. Q4 2025
New holders
101
288 more added
Sold out
93
216 more reduced

11 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 675 institutions
Q1 2021: 199 institutionsQ2 2021: 203 institutionsQ3 2021: 193 institutionsQ4 2021: 214 institutionsQ1 2022: 224 institutionsQ2 2022: 214 institutionsQ3 2022: 238 institutionsQ4 2022: 225 institutionsQ1 2023: 230 institutionsQ2 2023: 223 institutionsQ3 2023: 252 institutionsQ4 2023: 271 institutionsQ1 2024: 288 institutionsQ2 2024: 378 institutionsQ3 2024: 414 institutionsQ4 2024: 439 institutionsQ1 2025: 442 institutionsQ2 2025: 516 institutionsQ3 2025: 566 institutionsQ4 2025: 678 institutionsQ1 2026: 675 institutionsQ2 2026: 667 institutions
Value heldQ1 2026: $35.7B
Q1 2021: $3.63BQ2 2021: $3.46BQ3 2021: $3.40BQ4 2021: $3.36BQ1 2022: $2.97BQ2 2022: $2.55BQ3 2022: $2.74BQ4 2022: $2.87BQ1 2023: $2.48BQ2 2023: $3.09BQ3 2023: $3.72BQ4 2023: $4.64BQ1 2024: $4.07BQ2 2024: $11.7BQ3 2024: $13.7BQ4 2024: $13.3BQ1 2025: $15.3BQ2 2025: $21.2BQ3 2025: $30.3BQ4 2025: $37.8BQ1 2026: $35.7BQ2 2026: $23.8B
Institutions holding INSM and their total value by quarter
QuarterHoldersValue
Q2 2026667$23.8B
Q1 2026675$35.7B
Q4 2025678$37.8B
Q3 2025566$30.3B
Q2 2025516$21.2B
Q1 2025442$15.3B
Q4 2024439$13.3B
Q3 2024414$13.7B
Q2 2024378$11.7B
Q1 2024288$4.07B
Q4 2023271$4.64B
Q3 2023252$3.72B
Q2 2023223$3.09B
Q1 2023230$2.48B
Q4 2022225$2.87B
Q3 2022238$2.74B
Q2 2022214$2.55B
Q1 2022224$2.97B
Q4 2021214$3.36B
Q3 2021193$3.40B
Q2 2021203$3.46B
Q1 2021199$3.63B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q4 2025.

Institutions holding INSM in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Dimensional Fund Advisors LP400,900$65.5M0.01%+1,827+0.5%Added
Candriam Luxembourg S.C.A.401,735$65.7M0.34%+693+0.2%Added
Palo Alto Investors LP415,269$67.9M10.39%−74,213−15.2%Reduced
Samlyn Capital, LLC417,205$68.2M1.17%+47,630+12.9%Added
Janus Henderson Group PLC419,304$68.6M0.03%−381,251−47.6%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.467,753$76.5M0.09%+139,425+42.5%Added
Frontier Capital Management Co LLC469,561$76.8M0.79%+184,717+64.8%Added
Affinity Asset Advisors, LLC480,000$78.5M4.60%+30,000+6.7%Added
Ensign Peak Advisors, Inc499,756$81.7M0.15%+117,554+30.8%Added
Sumitomo Mitsui Trust Holdings, Inc.501,282$82.0M0.05%+65,840+15.1%Added
Royal Bank of Canada523,101$85.5M0.02%+16,290+3.2%Added
Nuveen, LLC534,750$87.4M0.02%−115,654−17.8%Reduced
Federated Hermes, Inc.538,257$88.0M0.14%−94,041−14.9%Reduced
Eventide Asset Management, LLC546,310$89.3M1.48%+62,721+13.0%Added
Deutsche Bank AG562,474$92.0M0.03%−27,556−4.7%Reduced
TimesSquare Capital Management, LLC584,798$95.6M1.62%+94,292+19.2%Added
Wells Fargo & Company597,384$97.7M0.02%+10,733+1.8%Added
BNP Paribas Arbitrage, SA604,600$98.9M0.07%−310,819−34.0%Reduced
Jennison Associates LLC604,694$98.9M0.07%+42,398+7.5%Added
GW&K Investment Management, LLC623,048$101.9M0.90%+140,378+29.1%Added
Swiss National Bank625,912$102.3M0.06%+46,800+8.1%Added
Artia Global Partners LP628,712$102.8M23.18%−53,500−7.8%Reduced
Clearbridge Investments, LLC643,435$105.2M0.09%−175,576−21.4%Reduced
Summit Partners Public Asset Management, LLC653,445$106.9M4.94%−255,635−28.1%Reduced
AQR Capital Management LLC675,485$108.8M0.05%+207,225+44.3%Added
Hood River Capital Management LLC688,554$112.6M1.13%+50,977+8.0%Added
Alliancebernstein L.P.688,734$119.9M0.04%+46,015+7.2%Added
Raymond James Financial Inc775,148$121.4M0.04%−4,106−0.5%Reduced
Legal & General Group Plc787,079$128.7M0.03%+246,766+45.7%Added
Amundi804,977$131.6M0.04%−112,021−12.2%Reduced
FIL Ltd828,947$135.5M0.11%−9,562−1.1%Reduced
Adage Capital Partners GP, L.L.C.900,000$147.2M0.23%+600,000+200.0%Added
William Blair Investment Management, LLC902,666$147.6M0.49%−318,430−26.1%Reduced
Principal Financial Group Inc916,464$149.9M0.08%+145,106+18.8%Added
American Century Companies Inc925,799$151.4M0.08%+740,709+400.2%Added
Goldman Sachs Group Inc942,646$154.1M0.02%−302,267−24.3%Reduced
Nwi Management LP1,014,000$165.8M10.14%+25,540+2.6%Added
Fiera Capital Corp1,021,970$167.1M0.57%+29,078+2.9%Added
Charles Schwab Investment Management Inc1,069,390$174.9M0.03%+42,035+4.1%Added
Pictet Asset Management Holding SA1,102,248$178.7M0.19%+143,285+14.9%Added
Nomura Asset Management International Inc.1,143,739$187.0M0.32%−39,290−3.3%Reduced
Duquesne Family Office LLCSuperinvestorDuquesne Family Office1,154,090$188.7M6.43%−327,662−22.1%Reduced
Millennium Management LLC1,157,786$189.3M0.14%−153,868−11.7%Reduced
UBS Asset Management Americas Inc1,215,025$198.7M0.04%+271,719+28.8%Added
Paradigm Biocapital Advisors LP1,254,488$205.1M4.19%+1,254,488New
Bank of New York Mellon Corp1,262,749$206.5M0.04%−127,293−9.2%Reduced
Castle Hook Partners LP1,269,754$207.6M4.20%+16,186+1.3%Added
Northern Trust Corp1,294,000$211.6M0.03%+55,562+4.5%Added
Morgan Stanley1,331,542$217.7M0.01%−300,364−18.4%Reduced
Vanguard Fiduciary Trust Co1,354,516$221.5M0.06%+1,354,516New
Capital World Investors1,362,291$222.7M0.03%+1,362,291New
SEI Investments Co1,395,794$228.2M0.21%+505,624+56.8%Added
Westfield Capital Management Co LP1,468,459$240.1M1.01%+1,035,938+239.5%Added
Integral Health Asset Management, LLC1,500,000$245.3M12.98%+250,000+20.0%Added
Bank of America Corp1,502,281$245.7M0.02%−223,400−12.9%Reduced
UBS Group AG1,737,481$284.1M0.05%−130,154−7.0%Reduced
Orbis Allan Gray Ltd1,872,824$306.2M1.29%−2,307,133−55.2%Reduced
Citadel Advisors LLC2,182,571$356.9M0.25%+1,025,276+88.6%Added
Franklin Resources Inc2,617,251$428.0M0.10%−138,285−5.0%Reduced
Ameriprise Financial Inc3,057,718$500.0M0.12%+1,088,861+55.3%Added
Price T Rowe Associates Inc3,092,807$505.7M0.06%−946,659−23.4%Reduced
Geode Capital Management, LLC4,450,389$733.3M0.05%+151,337+3.5%Added
RTW Investments, LP4,842,880$791.9M7.88%+10.0%Added
State Street Corp5,551,699$907.8M0.03%+349,955+6.7%Added
Capital International Investors5,595,194$914.9M0.21%+443,523+8.6%Added
D. E. Shaw & Co., Inc.5,625,825$919.9M0.72%+1,274,830+29.3%Added
Invesco Ltd.6,512,889$1.06B0.10%−1,005,449−13.4%Reduced
Artisan Partners Limited Partnership6,527,301$1.07B1.74%+1,683,552+34.8%Added
Baker Bros. Advisors LP7,421,111$1.21B6.97%+828,365+12.6%Added
Vanguard Capital Management LLC9,642,131$1.58B0.04%+9,642,131New
Vanguard Portfolio Management LLC10,371,802$1.70B0.09%+10,371,802New
FMR LLC13,160,167$2.15B0.11%+3,232,231+32.6%Added
Darwin Global Management, Ltd.16,805,184$2.58B68.33%−4,128,093−19.7%Reduced
BlackRock, Inc.16,678,146$2.73B0.05%+1,613,094+10.7%Added
JPMorgan Chase & Co24,150,499$3.70B0.25%+950,987+4.1%Added
Holocene Advisors, LP0$00.00%−801,165−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−395,000−100.0%Sold out
Zurich Insurance Group Ltd0$00.00%−281,098−100.0%Sold out
Alberta Investment Management Corp0$00.00%−206,532−100.0%Sold out
Novo Holdings A/S0$00.00%−200,000−100.0%Sold out
Caption Management, LLC0$00.00%−130,000−100.0%Sold out
Suvretta Capital Management, LLC0$00.00%−109,313−100.0%Sold out
Skandinaviska Enskilda Banken AB (publ)0$00.00%−96,353−100.0%Sold out
Atika Capital Management LLC0$00.00%−77,200−100.0%Sold out
Royce & Associates LP0$00.00%−59,705−100.0%Sold out
Picton Mahoney Asset Management0$00.00%−57,259−100.0%Sold out
Monashee Investment Management LLC0$00.00%−50,000−100.0%Sold out
Twinbeech Capital LP0$00.00%−44,009−100.0%Sold out
Freestone Grove Partners LP0$00.00%−36,200−100.0%Sold out
Acuta Capital Partners, LLC0$00.00%−25,878−100.0%Sold out
OrbiMed Advisors LLC0$00.00%−25,400−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−21,910−100.0%Sold out
Avidity Partners Management LP0$00.00%−17,700−100.0%Sold out
Verition Fund Management LLC0$00.00%−16,043−100.0%Sold out
West Michigan Advisors, LLC0$00.00%−15,418−100.0%Sold out
Main Management ETF Advisors, LLC0$00.00%−13,311−100.0%Sold out
Fedenia Advisers LLC0$00.00%−12,927−100.0%Sold out
EAM Investors, LLC0$00.00%−12,924−100.0%Sold out
October Effect Ltd0$00.00%−12,121−100.0%Sold out
Virtu Financial LLC0$00.00%−10,922−100.0%Sold out