INSMED Inc
INSM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001104506
In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.
13F holders, Q4 2025
Institutional positions in INSMED Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 678
- +121 vs. Q3 2025
- Shares held
- 217.4M
- +6.76M (+3.2%) vs. Q3 2025
- Total value
- $37.8B
- +$7.55B (+24.9%) vs. Q3 2025
- New holders
- 202
- 241 more added
- Sold out
- 81
- 180 more reduced
9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 667 | $23.8B |
| Q1 2026 | 675 | $35.7B |
| Q4 2025 | 678 | $37.8B |
| Q3 2025 | 566 | $30.3B |
| Q2 2025 | 516 | $21.2B |
| Q1 2025 | 442 | $15.3B |
| Q4 2024 | 439 | $13.3B |
| Q3 2024 | 414 | $13.7B |
| Q2 2024 | 378 | $11.7B |
| Q1 2024 | 288 | $4.07B |
| Q4 2023 | 271 | $4.64B |
| Q3 2023 | 252 | $3.72B |
| Q2 2023 | 223 | $3.09B |
| Q1 2023 | 230 | $2.48B |
| Q4 2022 | 225 | $2.87B |
| Q3 2022 | 238 | $2.74B |
| Q2 2022 | 214 | $2.55B |
| Q1 2022 | 224 | $2.97B |
| Q4 2021 | 214 | $3.36B |
| Q3 2021 | 193 | $3.40B |
| Q2 2021 | 203 | $3.46B |
| Q1 2021 | 199 | $3.63B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Nissay Asset Management Corp | 57,665 | $10.0M | 0.05% | +57,665 | New |
| Arizona State Retirement System | 57,931 | $10.1M | 0.05% | +1,767+3.1% | Added |
| Agf Management Ltd | 58,835 | $10.2M | 0.04% | +58,835 | New |
| Swedbank AB | 59,552 | $10.4M | 0.01% | +59,552 | New |
| Royce & Associates LP | 59,705 | $10.4M | 0.11% | −32,671−35.4% | Reduced |
| Tang Capital Management LLC | 60,000 | $10.4M | 0.52% | −140,000−70.0% | Reduced |
| Alyeska Investment Group, L.P. | 60,000 | $10.4M | 0.03% | +60,000 | New |
| Resona Asset Management Co.,Ltd. | 60,381 | $10.5M | 0.05% | +60,381 | New |
| Bank of Nova Scotia | 60,775 | $10.6M | 0.02% | −445,470−88.0% | Reduced |
| Essex Investment Management Co LLC | 62,423 | $10.9M | 1.66% | −24,654−28.3% | Reduced |
| Bank of Montreal | 62,800 | $10.9M | 0.00% | −28,966−31.6% | Reduced |
| Public Employees Retirement System of Ohio | 63,027 | $11.0M | 0.03% | +4,836+8.3% | Added |
| Handelsbanken Fonder AB | 63,581 | $11.1M | 0.03% | +13,400+26.7% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 65,313 | $11.4M | 0.02% | +65,313 | New |
| Squarepoint Ops LLC | 66,402 | $11.6M | 0.02% | +66,402 | New |
| SG Americas Securities, LLC | 66,762 | $11.6M | 0.02% | +49,356+283.6% | Added |
| Schroder Investment Management Group | 67,389 | $11.7M | 0.01% | −3,532−5.0% | Reduced |
| Stifel Financial Corp | 69,238 | $12.1M | 0.01% | −622−0.9% | Reduced |
| Creative Planning | 70,502 | $12.3M | 0.01% | +647+0.9% | Added |
| Silverarc Capital Management, LLC | 71,256 | $12.4M | 1.79% | −135,392−65.5% | Reduced |
| State of New Jersey Common Pension Fund D | 72,129 | $12.6M | 0.05% | +5,805+8.8% | Added |
| Korea Investment CORP | 72,629 | $12.6M | 0.02% | +72,629 | New |
| KLP Kapitalforvaltning AS | 74,000 | $12.9M | 0.05% | +33,000+80.5% | Added |
| Atika Capital Management LLC | 77,200 | $13.4M | 1.87% | −17,800−18.7% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 78,492 | $13.7M | 0.04% | +69,410+764.3% | Added |
| ExodusPoint Capital Management, LP | 80,087 | $13.9M | 0.16% | +80,087 | New |
| EULAV Asset Management | 81,000 | $14.1M | 0.38% | −9,000−10.0% | Reduced |
| Fred Alger Management, LLC | 81,311 | $14.2M | 0.06% | −12,722−13.5% | Reduced |
| Asset Management One Co.,Ltd. | 80,887 | $14.3M | 0.04% | +80,887 | New |
| Guggenheim Capital LLC | 82,291 | $14.3M | 0.11% | +45,431+123.3% | Added |
| Mitsubishi UFJ Trust & Banking Corp | 83,032 | $14.5M | 0.03% | +83,032 | New |
| Nomura Asset Management Co Ltd | 83,544 | $14.5M | 0.04% | +80,181+2,384.2% | Added |
| Treasurer of the State of North Carolina | 87,740 | $15.3M | 0.05% | +3,988+4.8% | Added |
| Van Eck Associates Corp | 89,035 | $15.5M | 0.01% | −17,667−16.6% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 89,088 | $15.5M | 0.13% | +6,574+8.0% | Added |
| Los Angeles Capital Management LLC | 82,385 | $16.0M | 0.05% | −45,118−35.4% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 96,353 | $16.8M | 0.07% | +41,569+75.9% | Added |
| Rafferty Asset Management, LLC | 100,812 | $17.5M | 0.06% | +45,653+82.8% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 103,308 | $18.0M | 0.03% | +48,779+89.5% | Added |
| Driehaus Capital Management LLC | 105,617 | $18.4M | 0.12% | +6,316+6.4% | Added |
| Assenagon Asset Management S.A. | 106,826 | $18.6M | 0.03% | −22,419−17.3% | Reduced |
| LMR Partners LLP | 107,510 | $18.7M | 0.18% | +13,598+14.5% | Added |
| National Bank of Canada | 108,706 | $18.9M | 0.02% | +106,225+4,281.5% | Added |
| Suvretta Capital Management, LLC | 109,313 | $19.0M | 0.47% | −108,470−49.8% | Reduced |
| Aviva PLC | 109,401 | $19.0M | 0.03% | +109,401 | New |
| Danske Bank A/S | 110,258 | $19.2M | 0.04% | +107,858+4,494.1% | Added |
| Rhenman & Partners Asset Management AB | 113,585 | $19.8M | 1.85% | −18,300−13.9% | Reduced |
| Man Group plc | 118,361 | $20.6M | 0.04% | +33,192+39.0% | Added |
| Manufacturers Life Insurance Company, The | 118,847 | $20.7M | 0.02% | −74,983−38.7% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 120,381 | $21.0M | 0.03% | +116,406+2,928.5% | Added |
| Evergreen Quality Fund GP, Ltd. | 120,500 | $21.0M | 0.41% | +120,500 | New |
| ING Groep NV | 122,945 | $21.4M | 0.13% | −250,555−67.1% | Reduced |
| HSBC Holdings PLC | 123,267 | $21.5M | 0.01% | +121,755+8,052.6% | Added |
| Long Focus Capital Management, LLC | 125,000 | $21.8M | 1.08% | −213,000−63.0% | Reduced |
| Caption Management, LLC | 130,000 | $22.6M | 1.00% | +129,919+160,393.8% | Added |
| Woodline Partners LP | 130,152 | $22.7M | 0.09% | +3,890+3.1% | Added |
| State of Wisconsin Investment Board | 131,624 | $22.9M | 0.05% | −1,741−1.3% | Reduced |
| LPL Financial LLC | 132,784 | $23.1M | 0.01% | +25,846+24.2% | Added |
| C WorldWide Group Holding A/S | 136,110 | $23.7M | 0.41% | −60,000−30.6% | Reduced |
| Perpetual Ltd | 141,517 | $24.6M | 0.36% | +141,517 | New |
| Russell Investments Group, Ltd. | 145,095 | $25.3M | 0.03% | −21,364−12.8% | Reduced |
| Sofinnova Investments, Inc. | 156,801 | $27.3M | 1.18% | +52,462+50.3% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 161,824 | $28.2M | 0.06% | +107,624+198.6% | Added |
| Tremblant Capital Group | 175,650 | $30.6M | 0.78% | +175,650 | New |
| State Board of Administration of Florida Retirement System | 180,295 | $31.4M | 0.06% | +45,275+33.5% | Added |
| Nicholas Investment Partners, LP | 180,410 | $31.4M | 2.29% | −410.0% | Reduced |
| American Century Companies Inc | 185,090 | $32.2M | 0.02% | +108,411+141.4% | Added |
| Susquehanna International Group, LLP | 188,576 | $32.8M | 0.05% | −44,530−19.1% | Reduced |
| Loomis Sayles & Co L P | 199,955 | $34.8M | 0.04% | −292,341−59.4% | Reduced |
| Novo Holdings A/S | 200,000 | $34.8M | 2.70% | 00.0% | Unchanged |
| Voya Investment Management LLC | 200,964 | $35.0M | 0.03% | −18,875−8.6% | Reduced |
| Alberta Investment Management Corp | 206,532 | $35.9M | 0.22% | +206,532 | New |
| Susquehanna Portfolio Strategies, LLC | 207,527 | $36.1M | 0.56% | 00.0% | Unchanged |
| Neuberger Berman Group LLC | 207,869 | $36.2M | 0.03% | +57,763+38.5% | Added |
| Eagle Health Investments LP | 210,900 | $36.7M | 8.07% | −60,700−22.3% | Reduced |
| Allspring Global Investments Holdings, LLC | 220,084 | $39.0M | 0.06% | −7,545−3.3% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 222,266 | $39.4M | 0.03% | +221,945+69,141.7% | Added |
| Citigroup Inc | 237,914 | $41.4M | 0.03% | +157,828+197.1% | Added |
| First Trust Advisors LP | 247,940 | $43.2M | 0.03% | +7,294+3.0% | Added |
| Standard Life Aberdeen plc | 253,112 | $44.1M | 0.07% | +18,490+7.9% | Added |
| Axiom Investors LLC | 255,849 | $44.5M | 0.39% | +148,116+137.5% | Added |
| TD Asset Management Inc | 262,478 | $45.7M | 0.04% | −135,778−34.1% | Reduced |
| First Turn Management, LLC | 264,293 | $46.0M | 5.26% | −55,480−17.3% | Reduced |
| Patient Square Capital LP | 267,000 | $46.5M | 9.95% | −59,400−18.2% | Reduced |
| Rhumbline Advisers | 268,326 | $46.7M | 0.04% | +55,423+26.0% | Added |
| Cormorant Asset Management, LP | 275,000 | $47.9M | 2.71% | −155,000−36.0% | Reduced |
| Envestnet Asset Management Inc | 276,105 | $48.1M | 0.01% | −66,680−19.5% | Reduced |
| New York State Common Retirement Fund | 276,284 | $48.1M | 0.06% | −169,592−38.0% | Reduced |
| National Pension Service | 280,442 | $48.8M | 0.04% | +280,442 | New |
| Zurich Insurance Group Ltd | 281,098 | $48.9M | 0.34% | +281,098 | New |
| Frontier Capital Management Co LLC | 284,844 | $49.6M | 0.53% | −44,040−13.4% | Reduced |
| Adage Capital Partners GP, L.L.C. | 300,000 | $52.2M | 0.08% | −952,503−76.0% | Reduced |
| California State Teachers Retirement System | 310,330 | $54.0M | 0.05% | +130,928+73.0% | Added |
| Rock Springs Capital Management LP | 319,250 | $55.6M | 2.85% | −65,750−17.1% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 328,328 | $57.2M | 0.07% | +129,626+65.2% | Added |
| ProShare Advisors LLC | 340,740 | $59.3M | 0.10% | +333,210+4,425.1% | Added |
| Polar Capital Holdings Plc | 344,228 | $59.9M | 0.27% | −27,659−7.4% | Reduced |
| California Public Employees Retirement System | 354,909 | $61.8M | 0.04% | +44,023+14.2% | Added |
| Gateway Investment Advisers LLC | 365,000 | $63.5M | 0.59% | +365,000 | New |
| Samlyn Capital, LLC | 369,575 | $64.3M | 1.03% | +76,932+26.3% | Added |