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INSMED Inc

INSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001104506

In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q4 2025

Institutional positions in INSMED Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
678
+121 vs. Q3 2025
Shares held
217.4M
+6.76M (+3.2%) vs. Q3 2025
Total value
$37.8B
+$7.55B (+24.9%) vs. Q3 2025
New holders
202
241 more added
Sold out
81
180 more reduced

9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 678 institutions
Q1 2021: 199 institutionsQ2 2021: 203 institutionsQ3 2021: 193 institutionsQ4 2021: 214 institutionsQ1 2022: 224 institutionsQ2 2022: 214 institutionsQ3 2022: 238 institutionsQ4 2022: 225 institutionsQ1 2023: 230 institutionsQ2 2023: 223 institutionsQ3 2023: 252 institutionsQ4 2023: 271 institutionsQ1 2024: 288 institutionsQ2 2024: 378 institutionsQ3 2024: 414 institutionsQ4 2024: 439 institutionsQ1 2025: 442 institutionsQ2 2025: 516 institutionsQ3 2025: 566 institutionsQ4 2025: 678 institutionsQ1 2026: 675 institutionsQ2 2026: 667 institutions
Value heldQ4 2025: $37.8B
Q1 2021: $3.63BQ2 2021: $3.46BQ3 2021: $3.40BQ4 2021: $3.36BQ1 2022: $2.97BQ2 2022: $2.55BQ3 2022: $2.74BQ4 2022: $2.87BQ1 2023: $2.48BQ2 2023: $3.09BQ3 2023: $3.72BQ4 2023: $4.64BQ1 2024: $4.07BQ2 2024: $11.7BQ3 2024: $13.7BQ4 2024: $13.3BQ1 2025: $15.3BQ2 2025: $21.2BQ3 2025: $30.3BQ4 2025: $37.8BQ1 2026: $35.7BQ2 2026: $23.8B
Institutions holding INSM and their total value by quarter
QuarterHoldersValue
Q2 2026667$23.8B
Q1 2026675$35.7B
Q4 2025678$37.8B
Q3 2025566$30.3B
Q2 2025516$21.2B
Q1 2025442$15.3B
Q4 2024439$13.3B
Q3 2024414$13.7B
Q2 2024378$11.7B
Q1 2024288$4.07B
Q4 2023271$4.64B
Q3 2023252$3.72B
Q2 2023223$3.09B
Q1 2023230$2.48B
Q4 2022225$2.87B
Q3 2022238$2.74B
Q2 2022214$2.55B
Q1 2022224$2.97B
Q4 2021214$3.36B
Q3 2021193$3.40B
Q2 2021203$3.46B
Q1 2021199$3.63B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q3 2025.

Institutions holding INSM in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Vestcor Inc4,238$738.0K0.02%+4,238New
CWM, LLC4,347$757.0K0.00%+1,892+77.1%Added
Summit Trail Advisors, LLC4,464$776.9K0.01%+2,731+157.6%Added
Rice Hall James & Associates, LLC4,536$789.4K0.04%−75,131−94.3%Reduced
Private Advisor Group, LLC4,667$812.2K0.00%−64−1.4%Reduced
B. Metzler seel. Sohn & Co. AG4,733$823.7K0.01%−348−6.8%Reduced
Intrust Bank NA4,735$824.1K0.07%−692−12.8%Reduced
Meeder Advisory Services, Inc.4,782$832.3K0.04%+570+13.5%Added
Voleon Capital Management LP4,883$849.8K0.02%−42,784−89.8%Reduced
Vident Advisory, LLC5,014$872.6K0.01%−544−9.8%Reduced
Resources Investment Advisors, LLC.5,032$875.8K0.01%+853+20.4%Added
Moody Aldrich Partners LLC5,036$876.5K0.16%−515−9.3%Reduced
Principal Securities, Inc.5,121$891.3K0.01%−1,883−26.9%Reduced
Pinkerton Retirement Specialists, LLC5,148$896.0K0.09%+5,148New
E. Ohman J:or Asset Management AB5,239$911.8K0.02%+5,239New
Tower Research Capital LLC (TRC)5,297$921.9K0.02%+3,955+294.7%Added
Fulton Bank, N.A.5,325$926.8K0.03%+146+2.8%Added
Captrust Financial Advisors5,384$937.0K0.00%−238−4.2%Reduced
Commonwealth Equity Services, LLC5,488$955.2K0.00%−45−0.8%Reduced
Ieq Capital, LLC5,563$968.2K0.00%+5,563New
Mercer Global Advisors Inc5,567$968.8K0.00%+2,045+58.1%Added
Groupama Asset Managment5,590$972.9K0.01%−7,585−57.6%Reduced
Havemeyer Place LP5,891$1.03M0.20%+5,891New
Prudential Financial Inc5,937$1.03M0.00%−5,033−45.9%Reduced
Sequoia Financial Advisors, LLC5,940$1.03M0.01%+3,633+157.5%Added
Park Capital Management, LLC5,989$1.04M0.75%+5,989New
XTX Topco Ltd6,098$1.06M0.03%+6,098New
Vise Technologies, Inc.6,314$1.10M0.02%+982+18.4%Added
J. Safra Sarasin Holding AG6,461$1.12M0.02%−1,096−14.5%Reduced
North Dakota State Investment Board6,558$1.14M0.04%+6,558New
Everence Capital Management Inc6,774$1.18M0.07%+331+5.1%Added
The PNC Financial Services Group, Inc.6,860$1.19M0.00%+49+0.7%Added
Himension Fund7,164$1.25M0.08%−1,423−16.6%Reduced
Colony Group, LLC7,174$1.25M0.00%+2,638+58.2%Added
Snowden Capital Advisors LLC7,234$1.26M0.03%−535−6.9%Reduced
Norinchukin Bank, The7,242$1.26M0.01%+7,242New
Wiley Bros.-Aintree Capital, LLC7,259$1.26M0.01%+1,213+20.1%Added
Macquarie Group Ltd7,293$1.27M0.01%−642,554−98.9%Reduced
Comerica Bank7,337$1.28M0.01%−154,467−95.5%Reduced
Landscape Capital Management, L.L.C.7,364$1.28M0.09%−20,830−73.9%Reduced
AlphaCentric Advisors LLC7,588$1.32M1.32%+7,588New
Ameritas Investment Partners, Inc.7,710$1.34M0.04%+7,710New
US Bancorp7,748$1.35M0.00%−903−10.4%Reduced
Castleark Management LLC7,790$1.36M0.04%+2,060+36.0%Added
FORA Capital, LLC7,942$1.38M0.17%+7,942New
Quantitative Investment Management, LLC8,148$1.42M0.14%+8,148New
S&CO Inc8,300$1.44M0.09%00.0%Unchanged
Royal London Asset Management Ltd8,510$1.48M0.00%+8,510New
DekaBank Deutsche Girozentrale50,000$1.49M0.00%00.0%Unchanged
Highland Capital Management, LLC8,558$1.49M0.07%+8,558New
Dai-Ichi Life Insurance Company, Ltd8,633$1.50M0.04%+8,633New
Waldron Private Wealth LLC8,810$1.53M0.06%+10+0.1%Added
QRG Capital Management, Inc.9,030$1.57M0.02%+2,610+40.7%Added
M&T Bank Corp9,150$1.59M0.01%+5,056+123.5%Added
Ikarian Capital, LLC9,337$1.63M0.21%−4,414−32.1%Reduced
Vestmark Advisory Solutions, Inc.9,514$1.66M0.02%+6,966+273.4%Added
Yorktown Management & Research Co Inc9,600$1.67M1.34%00.0%Unchanged
AG2R la Mondiale Gestion D'Actifs9,677$1.68M0.07%+9,677New
Jump Financial, LLC9,823$1.71M0.02%+9,823New
Abn Amro Investment Solutions9,989$1.74M0.03%+9,989New
Wealthfront Advisers LLC9,991$1.74M0.00%+9,991New
Ishara Investments LP10,000$1.74M2.03%+10,000New
AustralianSuper Pty Ltd10,005$1.74M0.01%+10,005New
WCM Investment Management, LLC10,368$1.80M0.00%−5,132−33.1%Reduced
Maryland State Retirement & Pension System10,484$1.82M0.04%+1,200+12.9%Added
Wealth Enhancement Advisory Services, LLC10,427$1.83M0.00%+2,829+37.2%Added
Virtu Financial LLC10,922$1.90M0.07%+10,922New
Gulf International Bank (UK) Ltd11,033$1.92M0.06%+11,033New
Sectoral Asset Management Inc11,182$1.95M1.56%−2,243−16.7%Reduced
PKO Investment Management Joint-Stock Co11,300$1.97M0.16%+11,300New
Draper Asset Management, LLC11,312$1.97M1.04%+973+9.4%Added
Osmosis Investment Management UK Ltd11,325$1.97M0.05%+11,325New
JustInvest LLC11,424$1.99M0.02%+1,872+19.6%Added
Arrowpoint Investment Partners (Singapore) Pte. Ltd.11,556$2.01M0.30%+11,556New
Emerald Advisers, LLC11,990$2.09M0.06%−403−3.3%Reduced
MYDA Advisors LLC12,000$2.09M0.59%00.0%Unchanged
October Effect Ltd12,121$2.11M2.32%+12,121New
Elo Mutual Pension Insurance Co12,409$2.16M0.03%−2,677−17.7%Reduced
MetLife Investment Management12,891$2.24M0.01%+1,518+13.3%Added
EAM Investors, LLC12,924$2.25M0.25%−35,048−73.1%Reduced
Fedenia Advisers LLC12,927$2.25M0.86%+12,927New
Oppenheimer Asset Management Inc.13,151$2.29M0.03%−2,702−17.0%Reduced
Emerald Mutual Fund Advisers Trust13,241$2.30M0.11%+919+7.5%Added
F/M Investments LLC13,241$2.30M0.09%+2,174+19.6%Added
Fideuram Asset Management (Ireland) dac11,158$2.31M0.19%+11,158New
Main Management ETF Advisors, LLC13,311$2.32M0.08%+136+1.0%Added
Jane Street Group, LLC13,505$2.35M0.00%−778,229−98.3%Reduced
Oak Ridge Investments LLC13,813$2.40M0.15%−8,323−37.6%Reduced
Bellevue Group AG13,915$2.42M0.05%−6,336−31.3%Reduced
Credit Agricole S A13,927$2.42M0.01%+13,927New
Eurizon Capital SGR S.p.A.13,969$2.43M0.01%+13,969New
Swiss Life Asset Management Ltd14,004$2.44M0.01%+5,288+60.7%Added
Investment Management Corp of Ontario14,221$2.48M0.03%+14,221New
Louisiana State Employees Retirement System14,300$2.49M0.04%+14,300New
Dark Forest Capital Management LP14,732$2.56M0.12%+5,490+59.4%Added
Federation des caisses Desjardins du Quebec15,142$2.63M0.01%+1,919+14.5%Added
Keybank National Association15,166$2.64M0.01%−1,550−9.3%Reduced
West Michigan Advisors, LLC15,418$2.68M0.62%−2,201−12.5%Reduced
Pacer Advisors, Inc.15,583$2.71M0.01%+15,583New
Truist Financial Corp15,733$2.74M0.00%−23,330−59.7%Reduced