Heron Therapeutics, Inc.
HRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000818033
No open-market purchases or sales by Heron Therapeutics, Inc. insiders were filed in the last 90 days; 163 institutions reported holding it in 13F filings for Q2 2026, worth $57.1M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Heron Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 170
- 0 vs. Q3 2025
- Shares held
- 156.5M
- +3.93M (+2.6%) vs. Q3 2025
- Total value
- $203.2M
- +$11.0M (+5.7%) vs. Q3 2025
- New holders
- 25
- 56 more added
- Sold out
- 25
- 44 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting HRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 163 | $57.1M |
| Q1 2026 | 167 | $125.6M |
| Q4 2025 | 170 | $203.2M |
| Q3 2025 | 172 | $192.4M |
| Q2 2025 | 171 | $272.1M |
| Q1 2025 | 165 | $274.5M |
| Q4 2024 | 161 | $175.8M |
| Q3 2024 | 173 | $242.4M |
| Q2 2024 | 190 | $453.7M |
| Q1 2024 | 161 | $330.5M |
| Q4 2023 | 151 | $191.2M |
| Q3 2023 | 141 | $121.9M |
| Q2 2023 | 149 | $114.7M |
| Q1 2023 | 162 | $163.1M |
| Q4 2022 | 176 | $289.5M |
| Q3 2022 | 186 | $514.2M |
| Q2 2022 | 174 | $321.6M |
| Q1 2022 | 186 | $620.5M |
| Q4 2021 | 200 | $1.07B |
| Q3 2021 | 197 | $1.16B |
| Q2 2021 | 189 | $1.61B |
| Q1 2021 | 193 | $1.48B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Heron Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Rubric Capital Management LP | 30,046,828 | $39.1M | 0.47% | +946,100+3.3% | Added |
| Clearline Capital LP | 12,235,239 | $15.9M | 1.20% | +2,522,712+26.0% | Added |
| Adage Capital Partners GP, L.L.C. | 11,185,325 | $14.5M | 0.02% | +946,100+9.2% | Added |
| BlackRock, Inc. | 10,218,236 | $13.3M | 0.00% | +230,776+2.3% | Added |
| Vanguard Group Inc | 9,820,384 | $12.8M | 0.00% | +1,360,600+16.1% | Added |
| Velan Capital Investment Management LP | 8,753,290 | $11.4M | 6.62% | 00.0% | Unchanged |
| Millennium Management LLC | 7,169,908 | $9.32M | 0.01% | +6,921,405+2,785.2% | Added |
| Palisade Capital Management LLC | 6,326,113 | $8.22M | 0.24% | −1,001,334−13.7% | Reduced |
| Tang Capital Management LLC | 6,250,000 | $8.13M | 0.40% | +2,800,000+81.2% | Added |
| Tejara Capital Ltd | 5,131,426 | $6.67M | 2.77% | +541,711+11.8% | Added |
| Geode Capital Management, LLC | 4,081,222 | $5.31M | 0.00% | +438,240+12.0% | Added |
| State Street Corp | 3,778,043 | $4.91M | 0.00% | +126,540+3.5% | Added |
| JW Asset Management, LLC | 3,671,073 | $4.77M | 1.55% | +378,440+11.5% | Added |
| Congress Park Capital LLC | 3,067,475 | $3.99M | 1.19% | +177,318+6.1% | Added |
| D. E. Shaw & Co., Inc. | 3,004,640 | $3.91M | 0.00% | −83,852−2.7% | Reduced |
| New York State Common Retirement Fund | 2,576,716 | $3.35M | 0.00% | 00.0% | Unchanged |
| Citadel Advisors LLC | 2,095,045 | $2.72M | 0.00% | −613,412−22.6% | Reduced |
| UBS Group AG | 2,091,669 | $2.72M | 0.00% | −842,412−28.7% | Reduced |
| Renaissance Technologies LLC | 1,915,900 | $2.49M | 0.00% | −939,099−32.9% | Reduced |
| Pale Fire Capital SE | 1,469,655 | $1.91M | 0.25% | +998,465+211.9% | Added |
| Charles Schwab Investment Management Inc | 1,415,336 | $1.84M | 0.00% | +138,295+10.8% | Added |
| Jane Street Group, LLC | 1,367,891 | $1.78M | 0.00% | +1,147,583+520.9% | Added |
| Stonepine Capital Management, LLC | 1,237,802 | $1.61M | 1.27% | +387,702+45.6% | Added |
| Monaco Asset Management SAM | 1,233,022 | $1.60M | 0.48% | +230,546+23.0% | Added |
| Northern Trust Corp | 1,091,411 | $1.42M | 0.00% | −66,162−5.7% | Reduced |
| Two Sigma Investments, LP | 999,509 | $1.30M | 0.00% | +307,230+44.4% | Added |
| Goldman Sachs Group Inc | 989,796 | $1.29M | 0.00% | −335,006−25.3% | Reduced |
| Morgan Stanley | 963,851 | $1.25M | 0.00% | −1,504,190−60.9% | Reduced |
| CM Management, LLC | 750,000 | $975.0K | 0.82% | 00.0% | Unchanged |
| Orchard Capital Managment, LLC | 680,432 | $884.6K | 0.77% | +3,142+0.5% | Added |
| Squarepoint Ops LLC | 677,947 | $881.3K | 0.00% | +462,840+215.2% | Added |
| Richmond Brothers, Inc. | 572,118 | $743.8K | 0.47% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 519,571 | $675.4K | 0.00% | +337,500+185.4% | Added |
| Highland Capital Management Fund Advisors, L.P. | 475,750 | $618.5K | 0.04% | 00.0% | Unchanged |
| Panagora Asset Management Inc | 440,252 | $572.3K | 0.00% | +440,252 | New |
| Bank of New York Mellon Corp | 418,477 | $544.0K | 0.00% | +6,003+1.5% | Added |
| AQR Capital Management LLC | 376,300 | $489.2K | 0.00% | −1,560,389−80.6% | Reduced |
| Nuveen, LLC | 347,065 | $451.2K | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 340,246 | $442.3K | 0.00% | +11,279+3.4% | Added |
| Invesco Ltd. | 307,861 | $400.2K | 0.00% | +76,466+33.0% | Added |
| Barclays PLC | 303,209 | $394.2K | 0.00% | +23,852+8.5% | Added |
| Apeiron RIA LLC | 259,968 | $358.8K | 0.07% | +37,090+16.6% | Added |
| Palumbo Wealth Management LLC | 259,413 | $337.2K | 0.08% | +42,907+19.8% | Added |
| Cyndeo Wealth Partners, LLC | 248,087 | $322.5K | 0.02% | 00.0% | Unchanged |
| Bridgeway Capital Management, LLC | 242,000 | $314.6K | 0.01% | −458,000−65.4% | Reduced |
| XTX Topco Ltd | 240,197 | $312.3K | 0.01% | +209,700+687.6% | Added |
| Quadrature Capital Ltd | 227,784 | $296.1K | 0.00% | +227,784 | New |
| Los Angeles Capital Management LLC | 248,567 | $283.4K | 0.00% | +2,154+0.9% | Added |
| Rhumbline Advisers | 203,319 | $264.3K | 0.00% | −21,334−9.5% | Reduced |
| Alliancebernstein L.P. | 198,550 | $258.1K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 179,620 | $233.5K | 0.00% | +56,488+45.9% | Added |
| Quinn Opportunity Partners LLC | 175,344 | $227.9K | 0.01% | 00.0% | Unchanged |
| Group One Trading, L.P. | 145,167 | $188.7K | 0.01% | +145,167 | New |
| Capital Planning Advisors, LLC | 144,095 | $187.3K | 0.03% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 135,089 | $176.0K | 0.02% | +34,908+34.8% | Added |
| Bank of America Corp | 134,445 | $174.8K | 0.00% | −597,628−81.6% | Reduced |
| Raymond James Financial Inc | 120,199 | $156.3K | 0.00% | +8,527+7.6% | Added |
| Simplex Trading, LLC | 114,604 | $149.0K | 0.00% | +87,734+326.5% | Added |
| Biltmore Family Office, LLC | 100,000 | $130.0K | 0.02% | 00.0% | Unchanged |
| Integrated Wealth Concepts LLC | 95,174 | $123.7K | 0.00% | −2,421−2.5% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 94,009 | $122.2K | 0.00% | +10,314+12.3% | Added |
| Deutsche Bank AG | 93,081 | $121.0K | 0.00% | +7,923+9.3% | Added |
| MetLife Investment Management | 87,754 | $114.1K | 0.00% | −4,672−5.1% | Reduced |
| Searle & Co. | 86,250 | $112.1K | 0.03% | 00.0% | Unchanged |
| FMR LLC | 84,197 | $109.5K | 0.00% | +36,803+77.7% | Added |
| Glenmede Trust Co NA | 82,189 | $106.8K | 0.00% | +82,189 | New |
| Price T Rowe Associates Inc | 76,638 | $100.0K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 71,369 | $92.8K | 0.00% | −491−0.7% | Reduced |
| Redwood Family Wealth LLC | 64,500 | $83.8K | 0.08% | +64,500 | New |
| JPMorgan Chase & Co | 62,396 | $81.1K | 0.00% | −1,230,048−95.2% | Reduced |
| Commonwealth Equity Services, LLC | 59,426 | $77.3K | 0.00% | −620−1.0% | Reduced |
| Intech Investment Management LLC | 59,369 | $77.2K | 0.00% | −13,996−19.1% | Reduced |
| State of Wyoming | 58,624 | $76.2K | 0.01% | +58,624 | New |
| Cornerstone Select Advisors, LLC | 58,070 | $75.5K | 0.05% | −1,000−1.7% | Reduced |
| LPL Financial LLC | 55,889 | $72.7K | 0.00% | +5,256+10.4% | Added |
| Headlands Technologies LLC | 51,287 | $66.7K | 0.01% | +31,431+158.3% | Added |
| Manufacturers Life Insurance Company, The | 48,659 | $63.3K | 0.00% | −3,309−6.4% | Reduced |
| Atom Investors LP | 48,178 | $62.6K | 0.00% | +48,178 | New |
| Abel Hall, LLC | 46,176 | $60.0K | 0.01% | +46,176 | New |
| Captrust Financial Advisors | 41,590 | $54.1K | 0.00% | −7,366−15.0% | Reduced |
| Prospera Financial Services Inc | 40,565 | $52.7K | 0.00% | −11,100−21.5% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 38,352 | $49.9K | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 35,106 | $45.6K | 0.01% | +27,040+335.2% | Added |
| Brevan Howard Capital Management LP | 35,036 | $45.5K | 0.00% | +35,036 | New |
| HSBC Holdings PLC | 33,381 | $43.9K | 0.00% | −53−0.2% | Reduced |
| BNP Paribas Arbitrage, SA | 32,870 | $42.7K | 0.00% | −345,718−91.3% | Reduced |
| Concurrent Investment Advisors, LLC | 31,923 | $41.5K | 0.00% | +31,923 | New |
| King Wealth | 30,799 | $40.0K | 0.00% | +1,000+3.4% | Added |
| Anfield Capital Management, LLC | 30,000 | $39.0K | 0.01% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 28,409 | $36.9K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 28,075 | $36.5K | 0.00% | +1,916+7.3% | Added |
| Jones Financial Companies LLLP | 27,955 | $36.3K | 0.00% | +3,867+16.1% | Added |
| Voya Investment Management LLC | 27,653 | $35.9K | 0.00% | 00.0% | Unchanged |
| Valeo Financial Advisors, LLC | 26,697 | $34.7K | 0.00% | 00.0% | Unchanged |
| Cambridge Investment Research Advisors, Inc. | 26,422 | $34.0K | 0.00% | −200−0.8% | Reduced |
| ACT Advisors, LLC. | 25,808 | $33.5K | 0.01% | +227+0.9% | Added |
| Parkway Wealth Management Group, LLC | 25,000 | $32.5K | 0.00% | +25,000 | New |
| SG Americas Securities, LLC | 24,377 | $32.0K | 0.00% | +6,858+39.1% | Added |
| Victory Capital Management Inc | 20,914 | $27.2K | 0.00% | +29+0.1% | Added |
| Argent Advisors, Inc. | 20,000 | $26.0K | 0.01% | 00.0% | Unchanged |