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Heron Therapeutics, Inc.

HRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000818033

No open-market purchases or sales by Heron Therapeutics, Inc. insiders were filed in the last 90 days; 163 institutions reported holding it in 13F filings for Q2 2026, worth $57.1M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Heron Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
167
+2 vs. Q4 2025
Shares held
156.9M
+10.2M (+7.0%) vs. Q4 2025
Total value
$125.6M
−$64.8M (−34.0%) vs. Q4 2025
New holders
31
52 more added
Sold out
29
43 more reduced

5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting HRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 167 institutions
Q1 2021: 193 institutionsQ2 2021: 189 institutionsQ3 2021: 197 institutionsQ4 2021: 200 institutionsQ1 2022: 186 institutionsQ2 2022: 174 institutionsQ3 2022: 186 institutionsQ4 2022: 176 institutionsQ1 2023: 162 institutionsQ2 2023: 149 institutionsQ3 2023: 141 institutionsQ4 2023: 151 institutionsQ1 2024: 161 institutionsQ2 2024: 190 institutionsQ3 2024: 173 institutionsQ4 2024: 161 institutionsQ1 2025: 165 institutionsQ2 2025: 171 institutionsQ3 2025: 172 institutionsQ4 2025: 170 institutionsQ1 2026: 167 institutionsQ2 2026: 163 institutions
Value heldQ1 2026: $125.6M
Q1 2021: $1.48BQ2 2021: $1.61BQ3 2021: $1.16BQ4 2021: $1.07BQ1 2022: $620.5MQ2 2022: $321.6MQ3 2022: $514.2MQ4 2022: $289.5MQ1 2023: $163.1MQ2 2023: $114.7MQ3 2023: $121.9MQ4 2023: $191.2MQ1 2024: $330.5MQ2 2024: $453.7MQ3 2024: $242.4MQ4 2024: $175.8MQ1 2025: $274.5MQ2 2025: $272.1MQ3 2025: $192.4MQ4 2025: $203.2MQ1 2026: $125.6MQ2 2026: $57.1M
Institutions holding HRTX and their total value by quarter
QuarterHoldersValue
Q2 2026163$57.1M
Q1 2026167$125.6M
Q4 2025170$203.2M
Q3 2025172$192.4M
Q2 2025171$272.1M
Q1 2025165$274.5M
Q4 2024161$175.8M
Q3 2024173$242.4M
Q2 2024190$453.7M
Q1 2024161$330.5M
Q4 2023151$191.2M
Q3 2023141$121.9M
Q2 2023149$114.7M
Q1 2023162$163.1M
Q4 2022176$289.5M
Q3 2022186$514.2M
Q2 2022174$321.6M
Q1 2022186$620.5M
Q4 2021200$1.07B
Q3 2021197$1.16B
Q2 2021189$1.61B
Q1 2021193$1.48B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Heron Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding HRTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Rubric Capital Management LP30,046,828$24.0M0.29%00.0%Unchanged
Clearline Capital LP12,235,239$9.79M0.76%00.0%Unchanged
BlackRock, Inc.10,106,422$8.09M0.00%−111,814−1.1%Reduced
OrbiMed Advisors LLC9,816,940$7.85M0.18%+9,816,940New
Velan Capital Investment Management LP8,753,290$7.00M4.39%00.0%Unchanged
Vanguard Capital Management LLC7,810,329$6.25M0.00%+7,810,329New
Millennium Management LLC7,630,527$6.11M0.00%+460,619+6.4%Added
Tejara Capital Ltd6,336,755$5.07M1.67%+1,205,329+23.5%Added
Tang Capital Management LLC6,250,000$5.00M0.25%00.0%Unchanged
Palisade Capital Management LLC6,140,639$4.91M0.16%−185,474−2.9%Reduced
Congress Park Capital LLC4,032,737$3.23M0.99%+965,262+31.5%Added
Geode Capital Management, LLC4,010,087$3.21M0.00%−71,135−1.7%Reduced
State Street Corp3,843,672$3.08M0.00%+65,629+1.7%Added
JW Asset Management, LLC3,751,073$3.00M1.23%+80,000+2.2%Added
Pale Fire Capital SE2,716,328$2.17M0.19%+1,246,673+84.8%Added
D. E. Shaw & Co., Inc.2,600,990$2.08M0.00%−403,650−13.4%Reduced
New York State Common Retirement Fund2,576,716$2.06M0.00%00.0%Unchanged
UBS Group AG2,285,883$1.83M0.00%+194,214+9.3%Added
Renaissance Technologies LLC1,718,300$1.37M0.00%−197,600−10.3%Reduced
Richmond Brothers, Inc.1,436,705$1.15M0.77%+864,587+151.1%Added
Stonepine Capital Management, LLC1,402,191$1.12M0.99%+164,389+13.3%Added
Charles Schwab Investment Management Inc1,376,367$1.10M0.00%−38,969−2.8%Reduced
Vanguard Portfolio Management LLC1,309,312$1.05M0.00%+1,309,312New
Northern Trust Corp1,172,525$938.1K0.00%+81,114+7.4%Added
Vanguard Fiduciary Trust Co1,152,714$922.2K0.00%+1,152,714New
Goldman Sachs Group Inc1,056,944$845.7K0.00%+67,148+6.8%Added
CM Management, LLC1,000,000$800.1K0.67%+250,000+33.3%Added
Panagora Asset Management Inc962,505$770.1K0.00%+522,253+118.6%Added
Squarepoint Ops LLC859,958$688.1K0.00%+182,011+26.8%Added
Monaco Asset Management SAM858,122$686.6K0.22%−374,900−30.4%Reduced
Citadel Advisors LLC759,269$607.5K0.00%−1,335,776−63.8%Reduced
Orchard Capital Managment, LLC680,432$544.4K0.71%00.0%Unchanged
AQR Capital Management LLC641,587$513.3K0.00%+265,287+70.5%Added
Nuveen, LLC526,293$421.1K0.00%+179,228+51.6%Added
Morgan Stanley513,413$410.8K0.00%−450,438−46.7%Reduced
Acadian Asset Management LLC513,168$409.0K0.00%+513,168New
Highland Capital Management Fund Advisors, L.P.475,750$380.6K0.03%00.0%Unchanged
Universal- Beteiligungs- und Servicegesellschaft mbH458,766$367.1K0.00%+458,766New
Palumbo Wealth Management LLC412,496$330.0K0.08%+153,083+59.0%Added
Bank of New York Mellon Corp406,806$325.5K0.00%−11,671−2.8%Reduced
Invesco Ltd.326,512$261.2K0.00%+18,651+6.1%Added
Alliancebernstein L.P.198,550$258.1K0.00%00.0%Unchanged
Two Sigma Investments, LP317,400$254.0K0.00%−682,109−68.2%Reduced
Caption Management, LLC313,681$251.0K0.01%+313,681New
Apeiron RIA LLC305,668$244.6K0.06%+45,700+17.6%Added
Susquehanna International Group, LLP288,253$230.6K0.00%−51,993−15.3%Reduced
Excelsior Advisor Network LLC285,609$228.5K0.09%+285,609New
Los Angeles Capital Management LLC243,003$194.4K0.00%−5,564−2.2%Reduced
XTX Topco Ltd209,481$167.6K0.00%−30,716−12.8%Reduced
Rhumbline Advisers184,549$147.6K0.00%−18,770−9.2%Reduced
Quinn Opportunity Partners LLC175,344$140.3K0.01%00.0%Unchanged
Bank of America Corp160,979$128.8K0.00%+26,534+19.7%Added
Raymond James Financial Inc138,203$110.6K0.00%+18,004+15.0%Added
Price T Rowe Associates Inc111,504$90.0K0.00%+34,866+45.5%Added
Gsa Capital Partners LLP105,064$84.0K0.01%−30,025−22.2%Reduced
Biltmore Family Office, LLC100,000$80.0K0.01%00.0%Unchanged
Integrated Wealth Concepts LLC95,498$76.4K0.00%+324+0.3%Added
Deutsche Bank AG93,081$74.5K0.00%00.0%Unchanged
Barclays PLC91,394$73.1K0.00%−211,815−69.9%Reduced
Group One Trading, L.P.86,809$69.5K0.00%−58,358−40.2%Reduced
Searle & Co.86,250$69.0K0.02%00.0%Unchanged
Vanguard Global Advisers, LLC83,756$67.0K0.00%+83,756New
Glenmede Trust Co NA82,050$65.6K0.00%−139−0.2%Reduced
LPL Financial LLC78,684$63.0K0.00%+22,795+40.8%Added
Mirae Asset Global ETFs Holdings Ltd.73,125$58.5K0.00%+1,756+2.5%Added
HORAN Wealth, LLC41,590$54.1K0.01%+41,590New
Ieq Capital, LLC66,966$53.6K0.00%+49,978+294.2%Added
Wells Fargo & Company66,543$53.2K0.00%−113,077−63.0%Reduced
Redwood Family Wealth LLC64,500$51.6K0.05%00.0%Unchanged
JPMorgan Chase & Co65,106$48.6K0.00%+2,710+4.3%Added
Commonwealth Equity Services, LLC59,726$47.8K0.00%+300+0.5%Added
Cornerstone Select Advisors, LLC59,414$47.5K0.03%+1,344+2.3%Added
FMR LLC58,195$46.6K0.00%−26,002−30.9%Reduced
Nine Masts Capital Ltd53,399$42.7K0.01%+53,399New
State of Wyoming50,618$40.5K0.00%−8,006−13.7%Reduced
Captrust Financial Advisors47,281$37.8K0.00%+5,691+13.7%Added
Manufacturers Life Insurance Company, The45,988$36.8K0.00%−2,671−5.5%Reduced
Intech Investment Management LLC42,150$33.7K0.00%−17,219−29.0%Reduced
Mercer Global Advisors Inc41,038$32.8K0.00%+27,658+206.7%Added
Prospera Financial Services Inc40,565$32.5K0.00%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey38,352$30.7K0.00%00.0%Unchanged
TopTier Wealth Management, LLC37,350$29.9K0.02%+37,350New
Mariner, LLC35,353$28.3K0.00%+16,354+86.1%Added
Chicago Partners Investment Group LLC26,764$27.3K0.00%+26,764New
R Squared Ltd33,615$26.9K0.01%+33,615New
HSBC Holdings PLC33,381$26.1K0.00%00.0%Unchanged
King Wealth32,799$26.0K0.00%+2,000+6.5%Added
BNP Paribas Arbitrage, SA32,454$26.0K0.00%−416−1.3%Reduced
Concurrent Investment Advisors, LLC31,923$25.5K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)31,482$25.2K0.00%+12,089+62.3%Added
Qube Research & Technologies Ltd30,355$24.3K0.00%+30,355New
Anfield Capital Management, LLC30,000$24.0K0.01%00.0%Unchanged
Jones Financial Companies LLLP30,062$23.5K0.00%+2,107+7.5%Added
CWM, LLC28,890$23.1K0.00%+18,262+171.8%Added
ACT Advisors, LLC.28,443$22.8K0.01%+2,635+10.2%Added
CoreCap Advisors, LLC28,409$22.7K0.00%00.0%Unchanged
Diversified Trust Co26,492$21.2K0.00%+26,492New
Parkway Wealth Management Group, LLC25,000$20.5K0.00%00.0%Unchanged
Voya Investment Management LLC25,601$20.5K0.00%−2,052−7.4%Reduced
Prudential Financial Inc23,495$18.8K0.00%+23,495New