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Heron Therapeutics, Inc.

HRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000818033

No open-market purchases or sales by Heron Therapeutics, Inc. insiders were filed in the last 90 days; 163 institutions reported holding it in 13F filings for Q2 2026, worth $57.1M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Heron Therapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
171
+7 vs. Q1 2025
Shares held
131.5M
+6.74M (+5.4%) vs. Q1 2025
Total value
$272.1M
−$2.26M (−0.8%) vs. Q1 2025
New holders
24
66 more added
Sold out
17
31 more reduced

1 institution that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting HRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 171 institutions
Q1 2021: 193 institutionsQ2 2021: 189 institutionsQ3 2021: 197 institutionsQ4 2021: 200 institutionsQ1 2022: 186 institutionsQ2 2022: 174 institutionsQ3 2022: 186 institutionsQ4 2022: 176 institutionsQ1 2023: 162 institutionsQ2 2023: 149 institutionsQ3 2023: 141 institutionsQ4 2023: 151 institutionsQ1 2024: 161 institutionsQ2 2024: 190 institutionsQ3 2024: 173 institutionsQ4 2024: 161 institutionsQ1 2025: 165 institutionsQ2 2025: 171 institutionsQ3 2025: 172 institutionsQ4 2025: 170 institutionsQ1 2026: 167 institutionsQ2 2026: 163 institutions
Value heldQ2 2025: $272.1M
Q1 2021: $1.48BQ2 2021: $1.61BQ3 2021: $1.16BQ4 2021: $1.07BQ1 2022: $620.5MQ2 2022: $321.6MQ3 2022: $514.2MQ4 2022: $289.5MQ1 2023: $163.1MQ2 2023: $114.7MQ3 2023: $121.9MQ4 2023: $191.2MQ1 2024: $330.5MQ2 2024: $453.7MQ3 2024: $242.4MQ4 2024: $175.8MQ1 2025: $274.5MQ2 2025: $272.1MQ3 2025: $192.4MQ4 2025: $203.2MQ1 2026: $125.6MQ2 2026: $57.1M
Institutions holding HRTX and their total value by quarter
QuarterHoldersValue
Q2 2026163$57.1M
Q1 2026167$125.6M
Q4 2025170$203.2M
Q3 2025172$192.4M
Q2 2025171$272.1M
Q1 2025165$274.5M
Q4 2024161$175.8M
Q3 2024173$242.4M
Q2 2024190$453.7M
Q1 2024161$330.5M
Q4 2023151$191.2M
Q3 2023141$121.9M
Q2 2023149$114.7M
Q1 2023162$163.1M
Q4 2022176$289.5M
Q3 2022186$514.2M
Q2 2022174$321.6M
Q1 2022186$620.5M
Q4 2021200$1.07B
Q3 2021197$1.16B
Q2 2021189$1.61B
Q1 2021193$1.48B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Heron Therapeutics, Inc.; share changes are against Q1 2025.

Institutions holding HRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Rubric Capital Management LP26,713,503$55.3M0.89%00.0%Unchanged
BlackRock, Inc.10,101,715$20.9M0.00%+1,538,296+18.0%Added
Vanguard Group Inc8,471,460$17.5M0.00%+245,875+3.0%Added
Adage Capital Partners GP, L.L.C.7,852,000$16.3M0.03%00.0%Unchanged
Velan Capital Investment Management LP6,986,744$14.5M14.47%00.0%Unchanged
Palisade Capital Management LLC5,086,903$10.5M0.30%−200,028−3.8%Reduced
Tejara Capital Ltd4,517,415$9.35M4.34%−59,992−1.3%Reduced
Geode Capital Management, LLC3,566,813$7.38M0.00%+453,085+14.6%Added
State Street Corp3,462,266$7.17M0.00%+208,362+6.4%Added
D. E. Shaw & Co., Inc.3,200,299$6.62M0.01%+214,102+7.2%Added
UBS Group AG3,184,965$6.59M0.00%+3,026,226+1,906.4%Added
AIGH Capital Management LLC3,009,257$6.23M2.92%+231,057+8.3%Added
Marshall Wace, LLP2,894,072$5.99M0.01%+1,639,376+130.7%Added
Price T Rowe Associates Inc2,881,677$5.97M0.00%−122,999−4.1%Reduced
Morgan Stanley2,761,591$5.72M0.00%+828,186+42.8%Added
Renaissance Technologies LLC2,689,339$5.57M0.01%+414,839+18.2%Added
JW Asset Management, LLC2,337,743$4.84M2.39%00.0%Unchanged
Congress Park Capital LLC2,268,249$4.70M1.54%+232,632+11.4%Added
Citadel Advisors LLC2,221,837$4.60M0.00%+1,720,347+343.0%Added
Tang Capital Management LLC2,135,459$4.42M0.22%−100,000−4.5%Reduced
New York State Common Retirement Fund1,760,045$3.64M0.00%+7,121+0.4%Added
Charles Schwab Investment Management Inc1,186,120$2.46M0.00%+96,671+8.9%Added
Northern Trust Corp1,152,621$2.39M0.00%+157,227+15.8%Added
Monaco Asset Management SAM1,080,000$2.24M0.85%+120,000+12.5%Added
Bank of America Corp1,075,269$2.23M0.00%+107,228+11.1%Added
Goldman Sachs Group Inc1,043,310$2.16M0.00%+14,632+1.4%Added
JPMorgan Chase & Co953,080$1.97M0.00%+256,637+36.8%Added
Two Sigma Investments, LP940,582$1.95M0.00%−112,399−10.7%Reduced
Clearline Capital LP857,166$1.77M0.16%−202,745−19.1%Reduced
Jacobs Levy Equity Management, Inc820,504$1.70M0.01%+820,504New
Bridgeway Capital Management, LLC700,000$1.45M0.03%00.0%Unchanged
Jefferies Financial Group Inc.666,800$1.38M0.02%+344,200+106.7%Added
Orchard Capital Managment, LLC659,933$1.37M1.51%−771,825−53.9%Reduced
Stonepine Capital Management, LLC657,380$1.36M1.34%−138,720−17.4%Reduced
CM Management, LLC600,000$1.24M1.13%00.0%Unchanged
Richmond Brothers, Inc.554,469$1.15M0.75%+9,568+1.8%Added
Two Sigma Advisers, LP533,771$1.10M0.00%−135,400−20.2%Reduced
Wellington Management Group LLP493,083$1.02M0.00%+5,841+1.2%Added
Millennium Management LLC492,337$1.02M0.00%−902,948−64.7%Reduced
Highland Capital Management Fund Advisors, L.P.475,750$984.8K0.09%00.0%Unchanged
Susquehanna International Group, LLP432,036$894.3K0.00%+232,655+116.7%Added
Bank of New York Mellon Corp402,111$832.4K0.00%+73,769+22.5%Added
TD Asset Management Inc394,600$816.8K0.00%00.0%Unchanged
Nuveen, LLC347,065$718.4K0.00%+32,790+10.4%Added
Jane Street Group, LLC331,386$686.0K0.00%+315,358+1,967.5%Added
Barclays PLC321,424$665.3K0.00%+138,878+76.1%Added
BNP Paribas Arbitrage, SA305,843$633.1K0.00%+31,898+11.6%Added
Walleye Capital LLC299,790$620.6K0.01%+299,790New
Gsa Capital Partners LLP297,321$615.0K0.04%+297,321New
Los Angeles Capital Management LLC266,128$550.9K0.00%+198,325+292.5%Added
Apeiron RIA LLC260,378$539.0K0.14%−2,164−0.8%Reduced
Wells Fargo & Company258,248$534.6K0.00%+181,082+234.7%Added
Cyndeo Wealth Partners, LLC248,087$513.5K0.03%+248,087New
Manufacturers Life Insurance Company, The241,048$499.0K0.00%+11,716+5.1%Added
Rhumbline Advisers222,438$460.4K0.00%+50,344+29.3%Added
Alliancebernstein L.P.198,550$411.0K0.00%00.0%Unchanged
Quinn Opportunity Partners LLC175,344$363.0K0.03%−104,656−37.4%Reduced
Invesco Ltd.173,081$358.3K0.00%+53,419+44.6%Added
Capital Planning Advisors, LLC144,095$298.3K0.04%+6,000+4.3%Added
Qube Research & Technologies Ltd132,782$274.9K0.00%+132,782New
Palumbo Wealth Management LLC132,433$274.1K0.08%+8,330+6.7%Added
Raymond James Financial Inc111,222$230.2K0.00%−25,000−18.4%Reduced
Biltmore Family Office, LLC101,467$210.0K0.04%00.0%Unchanged
Intech Investment Management LLC94,811$196.3K0.00%+13,725+16.9%Added
Integrated Wealth Concepts LLC94,405$195.4K0.00%+100+0.1%Added
MetLife Investment Management92,426$191.3K0.00%+37,738+69.0%Added
Searle & Co.86,250$178.5K0.05%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.83,756$173.4K0.00%+13,544+19.3%Added
Headlands Technologies LLC83,352$172.5K0.02%−9,206−9.9%Reduced
Principal Financial Group Inc80,284$166.2K0.00%−35,034−30.4%Reduced
Commonwealth Equity Services, LLC72,120$149.0K0.00%+4,819+7.2%Added
Glenmede Investment Management, LP70,250$145.4K0.00%+70,250New
Motiv8 Investments LLC69,245$143.3K0.09%00.0%Unchanged
Deutsche Bank AG67,729$140.2K0.00%−17,881−20.9%Reduced
J. Goldman & Co LP67,592$139.9K0.00%00.0%Unchanged
Simplex Trading, LLC62,460$129.0K0.00%+62,460New
AQR Capital Management LLC61,749$127.8K0.00%+34,440+126.1%Added
Squarepoint Ops LLC59,991$124.2K0.00%+59,991New
LPL Financial LLC52,503$108.7K0.00%−15,220−22.5%Reduced
Citigroup Inc51,953$107.5K0.00%−29,889−36.5%Reduced
FMR LLC51,320$106.2K0.00%+549+1.1%Added
Cornerstone Select Advisors, LLC49,670$102.8K0.09%−185−0.4%Reduced
Prospera Financial Services Inc49,665$102.8K0.00%+49,665New
HSBC Holdings PLC48,285$102.4K0.00%+1,180+2.5%Added
Captrust Financial Advisors47,621$98.6K0.00%+47,621New
Voya Investment Management LLC42,991$89.0K0.00%+10,767+33.4%Added
Horan Securities, Inc.41,590$86.1K0.03%00.0%Unchanged
Virtu Financial LLC39,593$82.0K0.00%+39,593New
Wealth Enhancement Advisory Services, LLC37,128$81.7K0.00%+1,512+4.2%Added
Creative Planning39,389$81.5K0.00%−59,063−60.0%Reduced
Police & Firemen's Retirement System of New Jersey38,352$79.4K0.00%+13,352+53.4%Added
Prudential Financial Inc36,465$75.5K0.00%+25,450+231.0%Added
Wealth Alliance32,000$66.2K0.01%00.0%Unchanged
D.A. Davidson & Co.31,500$65.2K0.00%00.0%Unchanged
ProShare Advisors LLC31,368$64.9K0.00%+5,953+23.4%Added
Anfield Capital Management, LLC30,000$62.1K0.02%−111,185−78.8%Reduced
King Wealth28,799$60.0K0.01%+2,000+7.5%Added
CoreCap Advisors, LLC28,463$58.9K0.00%−123−0.4%Reduced
Cambridge Investment Research Advisors, Inc.27,967$58.0K0.00%+100+0.4%Added
State Board of Administration of Florida Retirement System26,894$55.7K0.00%00.0%Unchanged