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Heron Therapeutics, Inc.

HRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000818033

No open-market purchases or sales by Heron Therapeutics, Inc. insiders were filed in the last 90 days; 163 institutions reported holding it in 13F filings for Q2 2026, worth $57.1M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Heron Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
172
+3 vs. Q2 2025
Shares held
152.7M
+21.3M (+16.2%) vs. Q2 2025
Total value
$192.4M
−$79.6M (−29.3%) vs. Q2 2025
New holders
19
57 more added
Sold out
16
52 more reduced

2 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting HRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 172 institutions
Q1 2021: 193 institutionsQ2 2021: 189 institutionsQ3 2021: 197 institutionsQ4 2021: 200 institutionsQ1 2022: 186 institutionsQ2 2022: 174 institutionsQ3 2022: 186 institutionsQ4 2022: 176 institutionsQ1 2023: 162 institutionsQ2 2023: 149 institutionsQ3 2023: 141 institutionsQ4 2023: 151 institutionsQ1 2024: 161 institutionsQ2 2024: 190 institutionsQ3 2024: 173 institutionsQ4 2024: 161 institutionsQ1 2025: 165 institutionsQ2 2025: 171 institutionsQ3 2025: 172 institutionsQ4 2025: 170 institutionsQ1 2026: 167 institutionsQ2 2026: 163 institutions
Value heldQ3 2025: $192.4M
Q1 2021: $1.48BQ2 2021: $1.61BQ3 2021: $1.16BQ4 2021: $1.07BQ1 2022: $620.5MQ2 2022: $321.6MQ3 2022: $514.2MQ4 2022: $289.5MQ1 2023: $163.1MQ2 2023: $114.7MQ3 2023: $121.9MQ4 2023: $191.2MQ1 2024: $330.5MQ2 2024: $453.7MQ3 2024: $242.4MQ4 2024: $175.8MQ1 2025: $274.5MQ2 2025: $272.1MQ3 2025: $192.4MQ4 2025: $203.2MQ1 2026: $125.6MQ2 2026: $57.1M
Institutions holding HRTX and their total value by quarter
QuarterHoldersValue
Q2 2026163$57.1M
Q1 2026167$125.6M
Q4 2025170$203.2M
Q3 2025172$192.4M
Q2 2025171$272.1M
Q1 2025165$274.5M
Q4 2024161$175.8M
Q3 2024173$242.4M
Q2 2024190$453.7M
Q1 2024161$330.5M
Q4 2023151$191.2M
Q3 2023141$121.9M
Q2 2023149$114.7M
Q1 2023162$163.1M
Q4 2022176$289.5M
Q3 2022186$514.2M
Q2 2022174$321.6M
Q1 2022186$620.5M
Q4 2021200$1.07B
Q3 2021197$1.16B
Q2 2021189$1.61B
Q1 2021193$1.48B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Heron Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding HRTX in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Rubric Capital Management LP29,100,728$36.7M0.49%+2,387,225+8.9%Added
Adage Capital Partners GP, L.L.C.10,239,225$12.9M0.02%+2,387,225+30.4%Added
BlackRock, Inc.9,987,460$12.6M0.00%−114,255−1.1%Reduced
Clearline Capital LP9,712,527$12.2M1.06%+8,855,361+1,033.1%Added
Velan Capital Investment Management LP8,753,290$11.0M10.36%+1,766,546+25.3%Added
Vanguard Group Inc8,459,784$10.7M0.00%−11,676−0.1%Reduced
Palisade Capital Management LLC7,327,447$9.23M0.25%+2,240,544+44.0%Added
Tejara Capital Ltd4,589,715$5.78M3.17%+72,300+1.6%Added
Baker Bros. Advisors LP4,251,951$5.36M0.04%+4,251,951New
State Street Corp3,651,503$4.60M0.00%+189,237+5.5%Added
Geode Capital Management, LLC3,642,982$4.59M0.00%+76,169+2.1%Added
Tang Capital Management LLC3,450,000$4.35M0.17%+1,314,541+61.6%Added
JW Asset Management, LLC3,292,633$4.15M1.99%+954,890+40.8%Added
D. E. Shaw & Co., Inc.3,088,492$3.89M0.00%−111,807−3.5%Reduced
UBS Group AG2,934,081$3.70M0.00%−250,884−7.9%Reduced
Congress Park Capital LLC2,890,157$3.64M1.13%+621,908+27.4%Added
Renaissance Technologies LLC2,854,999$3.60M0.00%+165,660+6.2%Added
Citadel Advisors LLC2,708,457$3.41M0.00%+486,620+21.9%Added
New York State Common Retirement Fund2,576,716$3.25M0.00%+816,671+46.4%Added
Citigroup Inc2,476,529$3.12M0.00%+2,424,576+4,666.9%Added
Morgan Stanley2,468,041$3.11M0.00%−293,550−10.6%Reduced
AQR Capital Management LLC1,936,689$2.44M0.00%+1,874,940+3,036.4%Added
Goldman Sachs Group Inc1,324,802$1.67M0.00%+281,492+27.0%Added
Marshall Wace, LLP1,308,861$1.65M0.00%−1,585,211−54.8%Reduced
JPMorgan Chase & Co1,292,444$1.63M0.00%+339,364+35.6%Added
Charles Schwab Investment Management Inc1,277,041$1.61M0.00%+90,921+7.7%Added
Northern Trust Corp1,157,573$1.46M0.00%+4,952+0.4%Added
Monaco Asset Management SAM1,002,476$1.26M0.47%−77,524−7.2%Reduced
Stonepine Capital Management, LLC850,100$1.07M0.87%+192,720+29.3%Added
CM Management, LLC750,000$945.0K0.79%+150,000+25.0%Added
Caption Management, LLC734,297$925.2K0.05%+734,297New
Bank of America Corp732,073$922.4K0.00%−343,196−31.9%Reduced
Bridgeway Capital Management, LLC700,000$882.0K0.02%00.0%Unchanged
Two Sigma Investments, LP692,279$872.3K0.00%−248,303−26.4%Reduced
Orchard Capital Managment, LLC677,290$853.4K1.13%+17,357+2.6%Added
Richmond Brothers, Inc.572,118$720.9K0.46%+17,649+3.2%Added
Wellington Management Group LLP525,774$662.5K0.00%+32,691+6.6%Added
Highland Capital Management Fund Advisors, L.P.475,750$599.4K0.05%00.0%Unchanged
Pale Fire Capital SE471,190$593.7K0.07%+471,190New
Bank of New York Mellon Corp412,474$519.7K0.00%+10,363+2.6%Added
BNP Paribas Arbitrage, SA378,588$477.0K0.00%+72,745+23.8%Added
Nuveen, LLC347,065$437.3K0.00%00.0%Unchanged
Susquehanna International Group, LLP328,967$414.5K0.00%−103,069−23.9%Reduced
Barclays PLC279,357$352.0K0.00%−42,067−13.1%Reduced
Millennium Management LLC248,503$313.1K0.00%−243,834−49.5%Reduced
Cyndeo Wealth Partners, LLC248,087$312.6K0.02%00.0%Unchanged
Los Angeles Capital Management LLC246,413$310.5K0.00%−19,715−7.4%Reduced
Invesco Ltd.231,395$291.6K0.00%+58,314+33.7%Added
Apeiron RIA LLC222,878$289.7K0.07%−37,500−14.4%Reduced
Rhumbline Advisers224,653$283.0K0.00%+2,215+1.0%Added
Jane Street Group, LLC220,308$277.6K0.00%−111,078−33.5%Reduced
Palumbo Wealth Management LLC216,506$272.8K0.09%+84,073+63.5%Added
Squarepoint Ops LLC215,107$271.0K0.00%+155,116+258.6%Added
Alliancebernstein L.P.198,550$250.2K0.00%00.0%Unchanged
Two Sigma Advisers, LP182,071$229.4K0.00%−351,700−65.9%Reduced
Quinn Opportunity Partners LLC175,344$220.9K0.02%00.0%Unchanged
Capital Planning Advisors, LLC144,095$181.6K0.02%00.0%Unchanged
Wells Fargo & Company123,132$155.1K0.00%−135,116−52.3%Reduced
Raymond James Financial Inc111,672$140.7K0.00%+450+0.4%Added
Glenmede Investment Management, LP105,326$132.7K0.00%+35,076+49.9%Added
Gsa Capital Partners LLP100,181$126.0K0.01%−197,140−66.3%Reduced
Biltmore Family Office, LLC100,000$126.0K0.02%−1,467−1.4%Reduced
Walleye Capital LLC99,335$125.2K0.00%−200,455−66.9%Reduced
Integrated Wealth Concepts LLC97,595$123.0K0.00%+3,190+3.4%Added
MetLife Investment Management92,426$116.5K0.00%00.0%Unchanged
Searle & Co.86,250$108.7K0.03%00.0%Unchanged
Deutsche Bank AG85,158$107.3K0.00%+17,429+25.7%Added
Connor, Clark & Lunn Investment Management Ltd.83,695$105.5K0.00%+83,695New
Ieq Capital, LLC79,025$99.6K0.00%+79,025New
Price T Rowe Associates Inc76,638$97.0K0.00%−2,805,039−97.3%Reduced
Intech Investment Management LLC73,365$92.4K0.00%−21,446−22.6%Reduced
Mirae Asset Global ETFs Holdings Ltd.71,860$90.5K0.00%−11,896−14.2%Reduced
Motiv8 Investments LLC69,245$87.2K0.05%00.0%Unchanged
J. Goldman & Co LP67,592$85.2K0.00%00.0%Unchanged
Commonwealth Equity Services, LLC60,046$76.0K0.00%−12,074−16.7%Reduced
Cornerstone Select Advisors, LLC59,070$74.4K0.05%+9,400+18.9%Added
Manufacturers Life Insurance Company, The51,968$65.5K0.00%−189,080−78.4%Reduced
Cerity Partners LLC51,712$65.2K0.00%+51,712New
Prospera Financial Services Inc51,665$65.1K0.00%+2,000+4.0%Added
LPL Financial LLC50,633$63.8K0.00%−1,870−3.6%Reduced
Captrust Financial Advisors48,956$61.7K0.00%+1,335+2.8%Added
FMR LLC47,394$59.7K0.00%−3,926−7.7%Reduced
CWM, LLC45,015$57.0K0.00%+39,643+738.0%Added
Police & Firemen's Retirement System of New Jersey38,352$48.3K0.00%00.0%Unchanged
Mariner, LLC35,899$45.2K0.00%+35,899New
Prudential Financial Inc34,465$43.4K0.00%−2,000−5.5%Reduced
SRS Capital Advisors, Inc.33,374$42.1K0.00%+33,374New
HSBC Holdings PLC33,434$42.0K0.00%−14,851−30.8%Reduced
Wealth Alliance32,000$40.3K0.00%00.0%Unchanged
XTX Topco Ltd30,497$38.4K0.00%+30,497New
King Wealth29,799$38.0K0.00%+1,000+3.5%Added
Anfield Capital Management, LLC30,000$37.8K0.01%00.0%Unchanged
CoreCap Advisors, LLC28,409$35.8K0.00%−54−0.2%Reduced
GWM Advisors LLC28,187$35.5K0.00%+1,618+6.1%Added
Voya Investment Management LLC27,653$34.8K0.00%−15,338−35.7%Reduced
Cambridge Investment Research Advisors, Inc.26,622$34.0K0.00%−1,345−4.8%Reduced
Voleon Capital Management LP26,940$33.9K0.00%+26,940New
Wealth Enhancement Advisory Services, LLC25,577$33.8K0.00%−11,551−31.1%Reduced
Mercer Global Advisors Inc26,709$33.7K0.00%+26,709New
Valeo Financial Advisors, LLC26,697$33.6K0.00%+8,418+46.1%Added