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Heron Therapeutics, Inc.

HRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000818033

No open-market purchases or sales by Heron Therapeutics, Inc. insiders were filed in the last 90 days; 163 institutions reported holding it in 13F filings for Q2 2026, worth $57.1M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Heron Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
170
0 vs. Q3 2025
Shares held
156.5M
+3.93M (+2.6%) vs. Q3 2025
Total value
$203.2M
+$11.0M (+5.7%) vs. Q3 2025
New holders
25
56 more added
Sold out
25
44 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting HRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 170 institutions
Q1 2021: 193 institutionsQ2 2021: 189 institutionsQ3 2021: 197 institutionsQ4 2021: 200 institutionsQ1 2022: 186 institutionsQ2 2022: 174 institutionsQ3 2022: 186 institutionsQ4 2022: 176 institutionsQ1 2023: 162 institutionsQ2 2023: 149 institutionsQ3 2023: 141 institutionsQ4 2023: 151 institutionsQ1 2024: 161 institutionsQ2 2024: 190 institutionsQ3 2024: 173 institutionsQ4 2024: 161 institutionsQ1 2025: 165 institutionsQ2 2025: 171 institutionsQ3 2025: 172 institutionsQ4 2025: 170 institutionsQ1 2026: 167 institutionsQ2 2026: 163 institutions
Value heldQ4 2025: $203.2M
Q1 2021: $1.48BQ2 2021: $1.61BQ3 2021: $1.16BQ4 2021: $1.07BQ1 2022: $620.5MQ2 2022: $321.6MQ3 2022: $514.2MQ4 2022: $289.5MQ1 2023: $163.1MQ2 2023: $114.7MQ3 2023: $121.9MQ4 2023: $191.2MQ1 2024: $330.5MQ2 2024: $453.7MQ3 2024: $242.4MQ4 2024: $175.8MQ1 2025: $274.5MQ2 2025: $272.1MQ3 2025: $192.4MQ4 2025: $203.2MQ1 2026: $125.6MQ2 2026: $57.1M
Institutions holding HRTX and their total value by quarter
QuarterHoldersValue
Q2 2026163$57.1M
Q1 2026167$125.6M
Q4 2025170$203.2M
Q3 2025172$192.4M
Q2 2025171$272.1M
Q1 2025165$274.5M
Q4 2024161$175.8M
Q3 2024173$242.4M
Q2 2024190$453.7M
Q1 2024161$330.5M
Q4 2023151$191.2M
Q3 2023141$121.9M
Q2 2023149$114.7M
Q1 2023162$163.1M
Q4 2022176$289.5M
Q3 2022186$514.2M
Q2 2022174$321.6M
Q1 2022186$620.5M
Q4 2021200$1.07B
Q3 2021197$1.16B
Q2 2021189$1.61B
Q1 2021193$1.48B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Heron Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding HRTX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Tower Research Capital LLC (TRC)19,393$25.2K0.00%+7,880+68.4%Added
Mariner, LLC18,999$24.7K0.00%−16,900−47.1%Reduced
Advisory Services Network, LLC18,874$24.5K0.00%+18,114+2,383.4%Added
StoneX Group Inc.18,809$24.5K0.00%+18,809New
David Loasby16,000$23.8K0.00%00.0%Unchanged
Capital Investment Counsel, Inc18,325$23.8K0.00%+18,325New
Cerity Partners LLC17,063$22.2K0.00%−34,649−67.0%Reduced
Ieq Capital, LLC16,988$22.1K0.00%−62,037−78.5%Reduced
HighTower Advisors, LLC16,796$21.8K0.00%−4,000−19.2%Reduced
J.W. Cole Advisors, Inc.16,000$20.8K0.00%00.0%Unchanged
Pekin Hardy Strauss, Inc.15,992$20.8K0.00%+15,992New
Ameritas Investment Partners, Inc.15,618$20.3K0.00%00.0%Unchanged
JustInvest LLC14,896$19.4K0.00%+75+0.5%Added
Legal & General Group Plc14,237$18.5K0.00%00.0%Unchanged
Cetera Investment Advisers13,997$18.2K0.00%00.0%Unchanged
Cresset Asset Management, LLC13,390$17.4K0.00%+13,390New
Mercer Global Advisors Inc13,380$17.4K0.00%−13,329−49.9%Reduced
Aigen Investment Management, LP12,717$16.5K0.00%+12,717New
SEI Investments Co12,685$16.5K0.00%00.0%Unchanged
Russell Investments Group, Ltd.12,671$16.5K0.00%−4,547−26.4%Reduced
Royal Bank of Canada11,793$16.0K0.00%+5,832+97.8%Added
Two Sigma Securities, LLC12,136$15.8K0.00%+12,136New
National Asset Management, Inc.12,117$15.8K0.00%00.0%Unchanged
Xponance, Inc.11,893$15.5K0.00%00.0%Unchanged
DLK Investment Management, LLC11,690$15.2K0.01%−10,500−47.3%Reduced
Ingalls & Snyder LLC11,415$15.0K0.00%00.0%Unchanged
CWM, LLC10,628$14.0K0.00%−34,387−76.4%Reduced
Venturi Wealth Management, LLC10,500$13.7K0.00%00.0%Unchanged
Red Door Wealth Management, LLC10,400$13.5K0.00%+10,400New
HB Wealth Management, LLC10,301$13.4K0.00%−1,169−10.2%Reduced
CIBC World Markets Corp10,165$13.2K0.00%+10,165New
XML Financial, LLC10,000$13.0K0.00%00.0%Unchanged
Lido Advisors, LLC10,072$12.7K0.00%00.0%Unchanged
HBK Sorce Advisory LLC10,000$12.6K0.00%00.0%Unchanged
California State Teachers Retirement System9,458$12.3K0.00%+943+11.1%Added
Allworth Financial LP9,329$12.1K0.00%+7,775+500.3%Added
Sterling Capital Management LLC7,976$10.4K0.00%−1,438−15.3%Reduced
JTC Employer Solutions Trusteee Ltd6,500$8.00K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.4,968$6.46K0.00%+1,077+27.7%Added
Comerica Bank4,951$6.44K0.00%−68−1.4%Reduced
Amalgamated Bank4,827$6.00K0.00%+780+19.3%Added
Global Retirement Partners, LLC4,018$5.22K0.00%00.0%Unchanged
Citigroup Inc3,478$4.52K0.00%−2,473,051−99.9%Reduced
Clearstead Advisors, LLC3,200$4.16K0.00%−1,561−32.8%Reduced
Essential Partners LLC2,200$2.86K0.00%−6,751−75.4%Reduced
N.E.W. Advisory Services LLC1,619$2.10K0.00%00.0%Unchanged
Bessemer Group Inc1,300$2.00K0.00%00.0%Unchanged
Optiver Holding B.V.1,088$1.41K0.00%−794−42.2%Reduced
Winch Advisory Services, LLC1,000$1.30K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC1,000$1.30K0.00%00.0%Unchanged
Harbour Investments, Inc.1,000$1.30K0.00%+1,000New
GAMMA Investing LLC889$1.16K0.00%+889New
EverSource Wealth Advisors, LLC641$8330.00%−1,104−63.3%Reduced
New England Capital Financial Advisors LLC475$6180.00%00.0%Unchanged
Rockefeller Capital Management L.P.415$5390.00%+354+580.3%Added
SJS Investment Consulting Inc.400$5200.00%00.0%Unchanged
IFP Advisors, Inc361$4690.00%−155−30.0%Reduced
Lodestone Wealth Management LLC250$3250.00%+250New
Parallel Advisors, LLC200$2600.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co188$2440.00%+188New
Pinnacle Wealth Planning Services, Inc.178$2310.00%+178New
SRS Capital Advisors, Inc.129$1680.00%−33,245−99.6%Reduced
AdvisorNet Financial, Inc110$1430.00%00.0%Unchanged
Evermay Wealth Management LLC100$1300.00%00.0%Unchanged
HighMark Wealth Management LLC100$1300.00%00.0%Unchanged
Fortitude Family Office, LLC79$1030.00%−10−11.2%Reduced
Rothschild Investment LLC55$720.00%+23+71.9%Added
Farther Finance Advisors, LLC52$680.00%+52New
SBI Securities Co., Ltd.1$10.00%00.0%Unchanged
Colony Group, LLC148,470––+129,855+697.6%Added
Baker Bros. Advisors LP0$00.00%−4,251,951−100.0%Sold out
Marshall Wace, LLP0$00.00%−1,308,861−100.0%Sold out
Caption Management, LLC0$00.00%−734,297−100.0%Sold out
Wellington Management Group LLP0$00.00%−525,774−100.0%Sold out
Walleye Capital LLC0$00.00%−99,335−100.0%Sold out
Motiv8 Investments LLC0$00.00%−69,245−100.0%Sold out
J. Goldman & Co LP0$00.00%−67,592−100.0%Sold out
Prudential Financial Inc0$00.00%−34,465−100.0%Sold out
Wealth Alliance0$00.00%−32,000−100.0%Sold out
GWM Advisors LLC0$00.00%−28,187−100.0%Sold out
Voleon Capital Management LP0$00.00%−26,940−100.0%Sold out
Wealth Enhancement Advisory Services, LLC0$00.00%−25,577−100.0%Sold out
PKS Advisory Services, LLC0$00.00%−20,000−100.0%Sold out
Virtu Financial LLC0$00.00%−16,928−100.0%Sold out
Bank of Montreal0$00.00%−15,495−100.0%Sold out
R Squared Ltd0$00.00%−15,219−100.0%Sold out
Envestnet Asset Management Inc0$00.00%−14,780−100.0%Sold out
AE Wealth Management LLC0$00.00%−14,651−100.0%Sold out
D.A. Davidson & Co.0$00.00%−13,500−100.0%Sold out
Creative Planning0$00.00%−12,409−100.0%Sold out
Principal Financial Group Inc0$00.00%−11,654−100.0%Sold out
Gleason Group, Inc.0$00.00%−6,670−100.0%Sold out
Future Financial Wealth Managment LLC0$00.00%−3,500−100.0%Sold out
Financial Consulate, Inc0$00.00%−500−100.0%Sold out
CNB Bank0$00.00%−500−100.0%Sold out
Glenmede Investment Management, LP––––Not filed
CIBC Bancorp USA Inc.––––Not filed