Gyre Therapeutics, Inc.
GYRE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001124105
No open-market purchases or sales by Gyre Therapeutics, Inc. insiders were filed in the last 90 days; 59 institutions reported holding it in 13F filings for Q2 2026, worth $57.1M in total; no superinvestor holds it.
13F holders, Q4 2021
Institutional positions in Gyre Therapeutics, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 51
- −15 vs. Q3 2021
- Shares held
- 15.0M
- −3.34M (−18.1%) vs. Q3 2021
- Total value
- $13.7M
- −$61.9M (−81.8%) vs. Q3 2021
- New holders
- 12
- 11 more added
- Sold out
- 27
- 15 more reduced
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GYRE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 59 | $57.1M |
| Q1 2026 | 56 | $23.8M |
| Q4 2025 | 44 | $23.6M |
| Q3 2025 | 48 | $23.1M |
| Q2 2025 | 48 | $25.1M |
| Q1 2025 | 46 | $20.1M |
| Q4 2024 | 41 | $21.6M |
| Q3 2024 | 37 | $20.2M |
| Q2 2024 | 30 | $15.0M |
| Q1 2024 | 21 | $14.3M |
| Q4 2023 | 16 | $15.6M |
| Q3 2023 | 32 | $1.04M |
| Q2 2023 | 29 | $796.3K |
| Q1 2023 | 40 | $707.6K |
| Q4 2022 | 35 | $2.63M |
| Q3 2022 | 35 | $3.90M |
| Q2 2022 | 41 | $14.2M |
| Q1 2022 | 43 | $6.39M |
| Q4 2021 | 51 | $13.7M |
| Q3 2021 | 66 | $75.7M |
| Q2 2021 | 69 | $87.7M |
| Q1 2021 | 89 | $113.0M |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Gyre Therapeutics, Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Nantahala Capital Management, LLC | 2,761,660 | $2.52M | 0.16% | +329,448+13.5% | Added |
| Renaissance Technologies LLC | 1,771,908 | $1.62M | 0.00% | +1,732,123+4,353.7% | Added |
| OrbiMed Advisors LLC | 1,729,402 | $1.58M | 0.02% | −982,198−36.2% | Reduced |
| Vanguard Group Inc | 1,393,512 | $1.27M | 0.00% | −29,870−2.1% | Reduced |
| Sabby Management, LLC | 1,138,334 | $1.04M | 0.26% | +1,032,592+976.5% | Added |
| Millennium Management LLC | 909,238 | $831.0K | 0.00% | +238,014+35.5% | Added |
| Morgan Stanley | 514,228 | $470.0K | 0.00% | +436,148+558.6% | Added |
| Assenagon Asset Management S.A. | 512,643 | $469.0K | 0.00% | +512,643 | New |
| Dimensional Fund Advisors LP | 492,701 | $450.0K | 0.00% | −308,739−38.5% | Reduced |
| Ikarian Capital, LLC | 454,346 | $416.0K | 0.12% | 00.0% | Unchanged |
| Pura Vida Investments, LLC | 356,804 | $326.0K | 0.03% | −15,778−4.2% | Reduced |
| Two Sigma Investments, LP | 308,552 | $282.0K | 0.00% | +254,483+470.7% | Added |
| Geode Capital Management, LLC | 286,585 | $261.0K | 0.00% | −64,956−18.5% | Reduced |
| BlackRock Inc. | 257,284 | $235.0K | 0.00% | −13,434−5.0% | Reduced |
| Goldman Sachs Group Inc | 240,611 | $220.0K | 0.00% | +79,910+49.7% | Added |
| Acadian Asset Management LLC | 232,400 | $211.0K | 0.00% | +232,400 | New |
| Two Sigma Advisers, LP | 182,100 | $166.0K | 0.00% | +75,100+70.2% | Added |
| Gyon Technologies Capital Management, LP | 156,550 | $143.0K | 0.03% | +156,550 | New |
| D. E. Shaw & Co., Inc. | 140,186 | $128.0K | 0.00% | +140,186 | New |
| RBF Capital, LLC | 132,396 | $121.0K | 0.01% | 00.0% | Unchanged |
| Kynam Capital Management, LP | 110,991 | $101.0K | 0.05% | +110,991 | New |
| Northern Trust Corp | 102,156 | $93.0K | 0.00% | −1,214−1.2% | Reduced |
| CSS LLC | 88,656 | $81.0K | 0.00% | +55,107+164.3% | Added |
| Essex Woodlands Management, Inc. | 78,622 | $72.0K | 0.02% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 75,309 | $69.0K | 0.00% | 00.0% | Unchanged |
| State Street Corp | 72,599 | $66.0K | 0.00% | 00.0% | Unchanged |
| Johnson & Johnson | 66,951 | $61.0K | 0.01% | 00.0% | Unchanged |
| Marshall Wace, LLP | 67,605 | $61.0K | 0.00% | +67,605 | New |
| Virtu Financial LLC | 47,441 | $43.0K | 0.00% | +18,338+63.0% | Added |
| Boothbay Fund Management, LLC | 45,915 | $42.0K | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 40,928 | $38.0K | 0.00% | +40,928 | New |
| Raymond James & Associates | 32,800 | $30.0K | 0.00% | −96,753−74.7% | Reduced |
| HSBC Holdings PLC | 32,528 | $30.0K | 0.00% | 00.0% | Unchanged |
| Citadel Advisors LLC | 31,516 | $29.0K | 0.00% | −33,893−51.8% | Reduced |
| Barclays PLC | 30,102 | $28.0K | 0.00% | −3,748−11.1% | Reduced |
| Stephens Inc | 29,185 | $27.0K | 0.00% | +12,350+73.4% | Added |
| Bank of America Corp | 25,089 | $23.0K | 0.00% | −870−3.4% | Reduced |
| Black Diamond Financial, LLC | 18,000 | $16.0K | 0.01% | −24,000−57.1% | Reduced |
| Jane Street Group, LLC | 17,379 | $16.0K | 0.00% | +17,379 | New |
| Engineers Gate Manager LP | 16,076 | $15.0K | 0.00% | +16,076 | New |
| Colorado Capital Management, Inc. | 13,712 | $12.0K | 0.01% | 00.0% | Unchanged |
| Commonwealth Equity Services, LLC | 10,000 | $9.00K | 0.00% | 00.0% | Unchanged |
| Geneos Wealth Management Inc. | 8,214 | $7.00K | 0.00% | +8,214 | New |
| Cutler Group LP | 5,500 | $5.00K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 5,205 | $5.00K | 0.00% | +5,205 | New |
| Simplex Trading, LLC | 2,294 | $2.00K | 0.00% | +2,294 | New |
| Steward Partners Investment Advisory, LLC | 1,000 | $1.00K | 0.00% | −7,000−87.5% | Reduced |
| BNP Paribas Arbitrage, SA | 464 | $424 | 0.00% | −73−13.6% | Reduced |
| American Portfolios Advisors | 215 | $197 | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 49 | $0 | 0.00% | −31,058−99.8% | Reduced |
| Wells Fargo & Company | 479 | $0 | 0.00% | 00.0% | Unchanged |
| Stonepine Capital Management, LLC | 0 | $0 | 0.00% | −2,635,014−100.0% | Sold out |
| 22NW, LP | 0 | $0 | 0.00% | −1,429,242−100.0% | Sold out |
| Ghost Tree Capital, LLC | 0 | $0 | 0.00% | −1,000,000−100.0% | Sold out |
| Sio Capital Management, LLC | 0 | $0 | 0.00% | −623,892−100.0% | Sold out |
| Acuta Capital Partners, LLC | 0 | $0 | 0.00% | −365,000−100.0% | Sold out |
| Bank of Montreal | 0 | $0 | 0.00% | −201,265−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −175,751−100.0% | Sold out |
| Parkman Healthcare Partners LLC | 0 | $0 | 0.00% | −133,449−100.0% | Sold out |
| AlphaCentric Advisors LLC | 0 | $0 | 0.00% | −114,000−100.0% | Sold out |
| Ergoteles LLC | 0 | $0 | 0.00% | −105,211−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −89,400−100.0% | Sold out |
| J. Goldman & Co LP | 0 | $0 | 0.00% | −60,755−100.0% | Sold out |
| Davenport & Co LLC | 0 | $0 | 0.00% | −59,400−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −53,788−100.0% | Sold out |
| Tocqueville Asset Management L.P. | 0 | $0 | 0.00% | −50,080−100.0% | Sold out |
| Raymond James Financial Services Advisors, Inc. | 0 | $0 | 0.00% | −49,812−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −40,520−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −25,527−100.0% | Sold out |
| PDT Partners, LLC | 0 | $0 | 0.00% | −21,563−100.0% | Sold out |
| Cherry Creek Investment Advisors, Inc. | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Kalos Management, Inc. | 0 | $0 | 0.00% | −16,710−100.0% | Sold out |
| Walleye Trading LLC | 0 | $0 | 0.00% | −13,507−100.0% | Sold out |
| Silverarc Capital Management, LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Total Clarity Wealth Management, Inc. | 0 | $0 | 0.00% | −2,000−100.0% | Sold out |
| Capital Advisory Group Advisory Services, LLC | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| Jacobi Capital Management LLC | 0 | $0 | 0.00% | −200−100.0% | Sold out |
| FMR LLC | 0 | $0 | 0.00% | −1−100.0% | Sold out |