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Gyre Therapeutics, Inc.

GYRE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001124105

No open-market purchases or sales by Gyre Therapeutics, Inc. insiders were filed in the last 90 days; 59 institutions reported holding it in 13F filings for Q2 2026, worth $57.1M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Gyre Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
48
0 vs. Q2 2025
Shares held
3.10M
−314.1K (−9.2%) vs. Q2 2025
Total value
$23.1M
−$1.97M (−7.9%) vs. Q2 2025
New holders
10
13 more added
Sold out
10
16 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GYRE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 48 institutions
Q1 2021: 89 institutionsQ2 2021: 69 institutionsQ3 2021: 66 institutionsQ4 2021: 51 institutionsQ1 2022: 43 institutionsQ2 2022: 41 institutionsQ3 2022: 35 institutionsQ4 2022: 35 institutionsQ1 2023: 40 institutionsQ2 2023: 29 institutionsQ3 2023: 32 institutionsQ4 2023: 16 institutionsQ1 2024: 21 institutionsQ2 2024: 30 institutionsQ3 2024: 37 institutionsQ4 2024: 41 institutionsQ1 2025: 46 institutionsQ2 2025: 48 institutionsQ3 2025: 48 institutionsQ4 2025: 44 institutionsQ1 2026: 56 institutionsQ2 2026: 59 institutions
Value heldQ3 2025: $23.1M
Q1 2021: $113.0MQ2 2021: $87.7MQ3 2021: $75.7MQ4 2021: $13.7MQ1 2022: $6.39MQ2 2022: $14.2MQ3 2022: $3.90MQ4 2022: $2.63MQ1 2023: $707.6KQ2 2023: $796.3KQ3 2023: $1.04MQ4 2023: $15.6MQ1 2024: $14.3MQ2 2024: $15.0MQ3 2024: $20.2MQ4 2024: $21.6MQ1 2025: $20.1MQ2 2025: $25.1MQ3 2025: $23.1MQ4 2025: $23.6MQ1 2026: $23.8MQ2 2026: $57.1M
Institutions holding GYRE and their total value by quarter
QuarterHoldersValue
Q2 202659$57.1M
Q1 202656$23.8M
Q4 202544$23.6M
Q3 202548$23.1M
Q2 202548$25.1M
Q1 202546$20.1M
Q4 202441$21.6M
Q3 202437$20.2M
Q2 202430$15.0M
Q1 202421$14.3M
Q4 202316$15.6M
Q3 202332$1.04M
Q2 202329$796.3K
Q1 202340$707.6K
Q4 202235$2.63M
Q3 202235$3.90M
Q2 202241$14.2M
Q1 202243$6.39M
Q4 202151$13.7M
Q3 202166$75.7M
Q2 202169$87.7M
Q1 202189$113.0M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Gyre Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding GYRE in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc1,150,559$8.58M0.00%+850+0.1%Added
BlackRock, Inc.659,397$4.92M0.00%−183,212−21.7%Reduced
Geode Capital Management, LLC374,620$2.80M0.00%−27,089−6.7%Reduced
State Street Corp182,753$1.36M0.00%+4,985+2.8%Added
SBI Securities Co., Ltd.167,866$1.25M0.03%−64,433−27.7%Reduced
Charles Schwab Investment Management Inc123,386$920.5K0.00%−6,034−4.7%Reduced
Northern Trust Corp116,342$867.9K0.00%−26,987−18.8%Reduced
State of Wisconsin Investment Board39,000$290.9K0.00%+1,330+3.5%Added
Millennium Management LLC35,751$266.7K0.00%+35,751New
Bank of New York Mellon Corp24,398$182.0K0.00%+409+1.7%Added
UBS Group AG22,962$171.3K0.00%+14,323+165.8%Added
Alliancebernstein L.P.21,830$162.9K0.00%+1,900+9.5%Added
STRS Ohio21,100$157.4K0.00%+7,800+58.6%Added
Goldman Sachs Group Inc18,034$134.5K0.00%+18,034New
Lazard Asset Management LLC14,932$111.4K0.00%+14,932New
Rhumbline Advisers13,432$100.2K0.00%−2,754−17.0%Reduced
Barclays PLC13,396$99.9K0.00%−10,608−44.2%Reduced
Jane Street Group, LLC12,958$96.7K0.00%+12,958New
Royal Bank of Canada12,395$92.0K0.00%+6,133+97.9%Added
Deutsche Bank AG10,927$81.5K0.00%00.0%Unchanged
FMR LLC10,204$76.1K0.00%−688−6.3%Reduced
Morgan Stanley8,981$67.0K0.00%−26,277−74.5%Reduced
Bank of America Corp6,687$49.9K0.00%+410+6.5%Added
Wells Fargo & Company5,558$41.5K0.00%−1,457−20.8%Reduced
State of Alaska, Department of Revenue5,219$38.0K0.00%+5,219New
Mirae Asset Global ETFs Holdings Ltd.4,203$31.4K0.00%−3,210−43.3%Reduced
JPMorgan Chase & Co3,694$27.6K0.00%−2,767−42.8%Reduced
New York State Common Retirement Fund2,700$20.1K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)2,694$20.1K0.00%+570+26.8%Added
BNP Paribas Arbitrage, SA2,163$16.1K0.00%+867+66.9%Added
Police & Firemen's Retirement System of New Jersey2,097$15.6K0.00%00.0%Unchanged
Russell Investments Group, Ltd.1,124$8.38K0.00%+1,124New
Legal & General Group Plc860$6.44K0.00%−653−43.2%Reduced
California State Teachers Retirement System848$6.33K0.00%+1+0.1%Added
Ameritas Investment Partners, Inc.683$5.09K0.00%00.0%Unchanged
Activest Wealth Management533$3.98K0.00%00.0%Unchanged
Citigroup Inc384$2.86K0.00%−5,553−93.5%Reduced
Amalgamated Bank241$2.00K0.00%00.0%Unchanged
Optiver Holding B.V.222$1.66K0.00%+222New
Simplex Trading, LLC164$1.00K0.00%+164New
Nisa Investment Advisors, LLC102$7610.00%+43+72.9%Added
Principal Securities, Inc.85$6340.00%00.0%Unchanged
Advisory Services Network, LLC66$4920.00%+66New
SRS Capital Advisors, Inc.57$4260.00%+57New
Advisor Group Holdings, Inc.38$2830.00%00.0%Unchanged
Sterling Capital Management LLC22$1640.00%−11−33.3%Reduced
CWM, LLC43$00.00%−80−65.0%Reduced
Covestor Ltd6$00.00%00.0%Unchanged
Susquehanna International Group, LLP0$00.00%−35,912−100.0%Sold out
Nuveen, LLC0$00.00%−17,594−100.0%Sold out
Verition Fund Management LLC0$00.00%−13,345−100.0%Sold out
American Century Companies Inc0$00.00%−11,291−100.0%Sold out
Aster Capital Management (DIFC) Ltd0$00.00%−1,447−100.0%Sold out
Raymond James Financial Inc0$00.00%−650−100.0%Sold out
GAMMA Investing LLC0$00.00%−124−100.0%Sold out
Rise Advisors, LLC0$00.00%−54−100.0%Sold out
Essential Partners LLC0$00.00%−2−100.0%Sold out
IFP Advisors, Inc0$00.00%−1−100.0%Sold out