Gyre Therapeutics, Inc.
GYRE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001124105
No open-market purchases or sales by Gyre Therapeutics, Inc. insiders were filed in the last 90 days; 59 institutions reported holding it in 13F filings for Q2 2026, worth $57.1M in total; no superinvestor holds it.
13F holders, Q3 2021
Institutional positions in Gyre Therapeutics, Inc. as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 66
- −1 vs. Q2 2021
- Shares held
- 18.4M
- −1.70M (−8.5%) vs. Q2 2021
- Total value
- $75.7M
- −$11.3M (−13.0%) vs. Q2 2021
- New holders
- 15
- 9 more added
- Sold out
- 16
- 31 more reduced
2 institutions that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GYRE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 59 | $57.1M |
| Q1 2026 | 56 | $23.8M |
| Q4 2025 | 44 | $23.6M |
| Q3 2025 | 48 | $23.1M |
| Q2 2025 | 48 | $25.1M |
| Q1 2025 | 46 | $20.1M |
| Q4 2024 | 41 | $21.6M |
| Q3 2024 | 37 | $20.2M |
| Q2 2024 | 30 | $15.0M |
| Q1 2024 | 21 | $14.3M |
| Q4 2023 | 16 | $15.6M |
| Q3 2023 | 32 | $1.04M |
| Q2 2023 | 29 | $796.3K |
| Q1 2023 | 40 | $707.6K |
| Q4 2022 | 35 | $2.63M |
| Q3 2022 | 35 | $3.90M |
| Q2 2022 | 41 | $14.2M |
| Q1 2022 | 43 | $6.39M |
| Q4 2021 | 51 | $13.7M |
| Q3 2021 | 66 | $75.7M |
| Q2 2021 | 69 | $87.7M |
| Q1 2021 | 89 | $113.0M |
Institutions, Q3 2021
Shares, value and share of portfolio for each institution holding Gyre Therapeutics, Inc.; share changes are against Q2 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| OrbiMed Advisors LLC | 2,711,600 | $11.1M | 0.12% | +593,000+28.0% | Added |
| Stonepine Capital Management, LLC | 2,635,014 | $10.8M | 4.93% | −441,362−14.3% | Reduced |
| Nantahala Capital Management, LLC | 2,432,212 | $10.0M | 0.59% | −99,148−3.9% | Reduced |
| 22NW, LP | 1,429,242 | $5.87M | 1.75% | 00.0% | Unchanged |
| Vanguard Group Inc | 1,423,382 | $5.85M | 0.00% | +1,051+0.1% | Added |
| Ghost Tree Capital, LLC | 1,000,000 | $4.11M | 1.36% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 801,440 | $3.29M | 0.00% | −124,266−13.4% | Reduced |
| Millennium Management LLC | 671,224 | $2.76M | 0.00% | −116,524−14.8% | Reduced |
| Sio Capital Management, LLC | 623,892 | $2.56M | 0.83% | 00.0% | Unchanged |
| Ikarian Capital, LLC | 454,346 | $1.87M | 0.43% | −126,854−21.8% | Reduced |
| Pura Vida Investments, LLC | 372,582 | $1.53M | 0.12% | +372,582 | New |
| Acuta Capital Partners, LLC | 365,000 | $1.50M | 0.53% | −320,000−46.7% | Reduced |
| Geode Capital Management, LLC | 351,541 | $1.44M | 0.00% | +19,062+5.7% | Added |
| BlackRock Inc. | 270,718 | $1.11M | 0.00% | −12,105−4.3% | Reduced |
| Bank of Montreal | 201,265 | $962.0K | 0.00% | −11,133−5.2% | Reduced |
| Gsa Capital Partners LLP | 175,751 | $722.0K | 0.07% | +6,216+3.7% | Added |
| Goldman Sachs Group Inc | 160,701 | $660.0K | 0.00% | −100,286−38.4% | Reduced |
| Parkman Healthcare Partners LLC | 133,449 | $548.0K | 0.14% | −260,000−66.1% | Reduced |
| RBF Capital, LLC | 132,396 | $544.0K | 0.03% | −25,795−16.3% | Reduced |
| Raymond James & Associates | 129,553 | $532.0K | 0.00% | −5,576−4.1% | Reduced |
| AlphaCentric Advisors LLC | 114,000 | $469.0K | 0.12% | −68,500−37.5% | Reduced |
| Two Sigma Advisers, LP | 107,000 | $440.0K | 0.00% | −45,900−30.0% | Reduced |
| Sabby Management, LLC | 105,742 | $435.0K | 0.10% | +105,742 | New |
| Ergoteles LLC | 105,211 | $432.0K | 0.02% | −3,289−3.0% | Reduced |
| Northern Trust Corp | 103,370 | $425.0K | 0.00% | −3,573−3.3% | Reduced |
| Schonfeld Strategic Advisors LLC | 89,400 | $367.0K | 0.00% | −5,400−5.7% | Reduced |
| Essex Woodlands Management, Inc. | 78,622 | $323.0K | 0.07% | 00.0% | Unchanged |
| Morgan Stanley | 78,080 | $321.0K | 0.00% | −28,029−26.4% | Reduced |
| Bank of New York Mellon Corp | 75,309 | $309.0K | 0.00% | 00.0% | Unchanged |
| State Street Corp | 72,599 | $298.0K | 0.00% | +29,200+67.3% | Added |
| Johnson & Johnson | 66,951 | $275.0K | 0.02% | +66,951 | New |
| Citadel Advisors LLC | 65,409 | $268.0K | 0.00% | +65,409 | New |
| J. Goldman & Co LP | 60,755 | $250.0K | 0.02% | +60,755 | New |
| Davenport & Co LLC | 59,400 | $244.0K | 0.00% | −10,000−14.4% | Reduced |
| Two Sigma Investments, LP | 54,069 | $222.0K | 0.00% | +15,813+41.3% | Added |
| HRT Financial LP | 53,788 | $221.0K | 0.00% | −36,012−40.1% | Reduced |
| Tocqueville Asset Management L.P. | 50,080 | $206.0K | 0.00% | −4,500−8.2% | Reduced |
| Raymond James Financial Services Advisors, Inc. | 49,812 | $205.0K | 0.00% | −225−0.4% | Reduced |
| Boothbay Fund Management, LLC | 45,915 | $189.0K | 0.01% | −20,510−30.9% | Reduced |
| Black Diamond Financial, LLC | 42,000 | $173.0K | 0.08% | 00.0% | Unchanged |
| Walleye Capital LLC | 40,520 | $167.0K | 0.01% | +40,520 | New |
| Renaissance Technologies LLC | 39,785 | $164.0K | 0.00% | −408,412−91.1% | Reduced |
| Barclays PLC | 33,850 | $139.0K | 0.00% | +218+0.6% | Added |
| CSS LLC | 33,549 | $138.0K | 0.01% | +33,549 | New |
| HSBC Holdings PLC | 32,528 | $134.0K | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 31,107 | $128.0K | 0.00% | −53,889−63.4% | Reduced |
| Virtu Financial LLC | 29,103 | $120.0K | 0.01% | +29,103 | New |
| Bank of America Corp | 25,959 | $107.0K | 0.00% | −5,042−16.3% | Reduced |
| Squarepoint Ops LLC | 25,527 | $105.0K | 0.00% | −21,533−45.8% | Reduced |
| PDT Partners, LLC | 21,563 | $89.0K | 0.01% | +9,769+82.8% | Added |
| Cherry Creek Investment Advisors, Inc. | 20,000 | $82.0K | 0.05% | +20,000 | New |
| Stephens Inc | 16,835 | $69.0K | 0.00% | −50−0.3% | Reduced |
| Kalos Management, Inc. | 16,710 | $58.0K | 0.02% | −700−4.0% | Reduced |
| Colorado Capital Management, Inc. | 13,712 | $56.0K | 0.04% | 00.0% | Unchanged |
| Walleye Trading LLC | 13,507 | $56.0K | 0.00% | +13,507 | New |
| Commonwealth Equity Services, LLC | 10,000 | $41.0K | 0.00% | +10,000 | New |
| Silverarc Capital Management, LLC | 10,000 | $41.0K | 0.02% | +10,000 | New |
| Steward Partners Investment Advisory, LLC | 8,000 | $33.0K | 0.00% | −2,000−20.0% | Reduced |
| Cutler Group LP | 5,500 | $22.0K | 0.00% | 00.0% | Unchanged |
| Total Clarity Wealth Management, Inc. | 2,000 | $8.00K | 0.00% | +2,000 | New |
| Capital Advisory Group Advisory Services, LLC | 1,000 | $4.00K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 537 | $2.21K | 0.00% | +44+8.9% | Added |
| Wells Fargo & Company | 479 | $2.00K | 0.00% | −23−4.6% | Reduced |
| Jacobi Capital Management LLC | 200 | $1.00K | 0.00% | 00.0% | Unchanged |
| American Portfolios Advisors | 215 | $884 | 0.00% | +215 | New |
| FMR LLC | 1 | $0 | 0.00% | +1 | New |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −387,101−100.0% | Sold out |
| Deutsche Bank AG | 0 | $0 | 0.00% | −194,933−100.0% | Sold out |
| Tibra Equities Europe Ltd | 0 | $0 | 0.00% | −79,200−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −55,219−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −32,220−100.0% | Sold out |
| Parametric Portfolio Associates LLC | 0 | $0 | 0.00% | −21,019−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −19,700−100.0% | Sold out |
| Quantitative Systematic Strategies LLC | 0 | $0 | 0.00% | −16,277−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −15,265−100.0% | Sold out |
| Charles Schwab Investment Management Inc | 0 | $0 | 0.00% | −13,113−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −6,508−100.0% | Sold out |
| UBS Group AG | 0 | $0 | 0.00% | −2,609−100.0% | Sold out |
| Royal Bank of Canada | 0 | $0 | 0.00% | −2,174−100.0% | Sold out |
| Federation des caisses Desjardins du Quebec | 0 | $0 | 0.00% | −1,125−100.0% | Sold out |
| New York State Common Retirement Fund | 0 | $0 | 0.00% | −257−100.0% | Sold out |
| Quadrant Capital Group LLC | 0 | $0 | 0.00% | −336−100.0% | Sold out |
| M Holdings Securities, Inc. | – | – | – | – | Not filed |
| Johnson & Johnson Innovation - JJDC, Inc. | – | – | – | – | Not filed |