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Gyre Therapeutics, Inc.

GYRE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001124105

No open-market purchases or sales by Gyre Therapeutics, Inc. insiders were filed in the last 90 days; 59 institutions reported holding it in 13F filings for Q2 2026, worth $57.1M in total; no superinvestor holds it.

13F holders, Q2 2021

Institutional positions in Gyre Therapeutics, Inc. as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
69
−20 vs. Q1 2021
Shares held
20.2M
−2.18M (−9.7%) vs. Q1 2021
Total value
$87.7M
−$25.3M (−22.4%) vs. Q1 2021
New holders
10
18 more added
Sold out
30
29 more reduced

Compare with Q1 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GYRE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2021: 69 institutions
Q1 2021: 89 institutionsQ2 2021: 69 institutionsQ3 2021: 66 institutionsQ4 2021: 51 institutionsQ1 2022: 43 institutionsQ2 2022: 41 institutionsQ3 2022: 35 institutionsQ4 2022: 35 institutionsQ1 2023: 40 institutionsQ2 2023: 29 institutionsQ3 2023: 32 institutionsQ4 2023: 16 institutionsQ1 2024: 21 institutionsQ2 2024: 30 institutionsQ3 2024: 37 institutionsQ4 2024: 41 institutionsQ1 2025: 46 institutionsQ2 2025: 48 institutionsQ3 2025: 48 institutionsQ4 2025: 44 institutionsQ1 2026: 56 institutionsQ2 2026: 59 institutions
Value heldQ2 2021: $87.7M
Q1 2021: $113.0MQ2 2021: $87.7MQ3 2021: $75.7MQ4 2021: $13.7MQ1 2022: $6.39MQ2 2022: $14.2MQ3 2022: $3.90MQ4 2022: $2.63MQ1 2023: $707.6KQ2 2023: $796.3KQ3 2023: $1.04MQ4 2023: $15.6MQ1 2024: $14.3MQ2 2024: $15.0MQ3 2024: $20.2MQ4 2024: $21.6MQ1 2025: $20.1MQ2 2025: $25.1MQ3 2025: $23.1MQ4 2025: $23.6MQ1 2026: $23.8MQ2 2026: $57.1M
Institutions holding GYRE and their total value by quarter
QuarterHoldersValue
Q2 202659$57.1M
Q1 202656$23.8M
Q4 202544$23.6M
Q3 202548$23.1M
Q2 202548$25.1M
Q1 202546$20.1M
Q4 202441$21.6M
Q3 202437$20.2M
Q2 202430$15.0M
Q1 202421$14.3M
Q4 202316$15.6M
Q3 202332$1.04M
Q2 202329$796.3K
Q1 202340$707.6K
Q4 202235$2.63M
Q3 202235$3.90M
Q2 202241$14.2M
Q1 202243$6.39M
Q4 202151$13.7M
Q3 202166$75.7M
Q2 202169$87.7M
Q1 202189$113.0M

Institutions, Q2 2021

Shares, value and share of portfolio for each institution holding Gyre Therapeutics, Inc.; share changes are against Q1 2021.

Institutions holding GYRE in Q2 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Stonepine Capital Management, LLC3,076,376$13.3M6.97%+626,183+25.6%Added
Nantahala Capital Management, LLC2,531,360$11.0M0.60%−29,974−1.2%Reduced
OrbiMed Advisors LLC2,118,600$9.17M0.09%00.0%Unchanged
22NW, LP1,429,242$6.19M1.66%+653,968+84.4%Added
Vanguard Group Inc1,422,331$6.16M0.00%−110,614−7.2%Reduced
Ghost Tree Capital, LLC1,000,000$4.33M1.35%00.0%Unchanged
Dimensional Fund Advisors LP925,706$4.01M0.00%+18,110+2.0%Added
Millennium Management LLC787,748$3.41M0.00%+248,474+46.1%Added
Acuta Capital Partners, LLC685,000$2.97M1.27%−254,500−27.1%Reduced
Sio Capital Management, LLC623,892$2.70M0.73%00.0%Unchanged
Ikarian Capital, LLC581,200$2.52M0.45%00.0%Unchanged
Renaissance Technologies LLC448,197$1.94M0.00%+448,197New
Parkman Healthcare Partners LLC393,449$1.70M0.37%+1,831+0.5%Added
Verition Fund Management LLC387,101$1.68M0.02%+105,294+37.4%Added
Geode Capital Management, LLC332,479$1.44M0.00%−201,893−37.8%Reduced
BlackRock Inc.282,823$1.23M0.00%−1,368,935−82.9%Reduced
Goldman Sachs Group Inc260,987$1.13M0.00%−1,384−0.5%Reduced
Bank of Montreal212,398$971.0K0.00%+56,789+36.5%Added
Deutsche Bank AG194,933$844.0K0.00%−70,224−26.5%Reduced
AlphaCentric Advisors LLC182,500$790.0K0.21%+122,500+204.2%Added
Gsa Capital Partners LLP169,535$734.0K0.08%+143,603+553.8%Added
RBF Capital, LLC158,191$685.0K0.04%+158,191New
Two Sigma Advisers, LP152,900$662.0K0.00%−97,000−38.8%Reduced
Raymond James & Associates135,129$585.0K0.00%+7,426+5.8%Added
Ergoteles LLC108,500$470.0K0.01%+108,500New
Northern Trust Corp106,943$463.0K0.00%−229,289−68.2%Reduced
Morgan Stanley106,109$458.0K0.00%+46,330+77.5%Added
Schonfeld Strategic Advisors LLC94,800$411.0K0.00%+9,400+11.0%Added
HRT Financial LP89,800$388.0K0.00%+89,800New
M Holdings Securities, Inc.85,202$369.0K0.04%−9,000−9.6%Reduced
JPMorgan Chase & Co84,996$368.0K0.00%−41,975−33.1%Reduced
Tibra Equities Europe Ltd79,200$343.0K0.11%+79,200New
Essex Woodlands Management, Inc.78,622$340.0K0.05%00.0%Unchanged
Bank of New York Mellon Corp75,309$326.0K0.00%−61,148−44.8%Reduced
Davenport & Co LLC69,400$301.0K0.00%+6,800+10.9%Added
Johnson & Johnson Innovation - JJDC, Inc.66,951$290.0K0.03%00.0%Unchanged
Boothbay Fund Management, LLC66,425$288.0K0.01%−2,000−2.9%Reduced
Susquehanna International Group, LLP55,219$239.0K0.00%+20,188+57.6%Added
Tocqueville Asset Management L.P.54,580$236.0K0.00%+15,000+37.9%Added
Raymond James Financial Services Advisors, Inc.50,037$217.0K0.00%−51,500−50.7%Reduced
Squarepoint Ops LLC47,060$204.0K0.00%−22,734−32.6%Reduced
State Street Corp43,399$188.0K0.00%−334,835−88.5%Reduced
Black Diamond Financial, LLC42,000$182.0K0.07%+4,000+10.5%Added
Two Sigma Investments, LP38,256$166.0K0.00%−176,310−82.2%Reduced
Barclays PLC33,632$145.0K0.00%−22,209−39.8%Reduced
HSBC Holdings PLC32,528$141.0K0.00%+5,085+18.5%Added
Trexquant Investment LP32,220$140.0K0.01%+32,220New
Bank of America Corp31,001$134.0K0.00%−29,607−48.8%Reduced
Parametric Portfolio Associates LLC21,019$91.0K0.00%−22,715−51.9%Reduced
Advisory Services Network, LLC19,700$85.0K0.00%+19,700New
Kalos Management, Inc.17,410$74.0K0.03%−400−2.2%Reduced
Stephens Inc16,885$73.0K0.00%+6,625+64.6%Added
Quantitative Systematic Strategies LLC16,277$70.0K0.02%−13,720−45.7%Reduced
XTX Topco Ltd15,265$66.0K0.02%+15,265New
Colorado Capital Management, Inc.13,712$59.0K0.04%00.0%Unchanged
Charles Schwab Investment Management Inc13,113$57.0K0.00%−65,628−83.3%Reduced
PDT Partners, LLC11,794$51.0K0.00%−43,206−78.6%Reduced
Steward Partners Investment Advisory, LLC10,000$43.0K0.00%00.0%Unchanged
Group One Trading, L.P.6,508$28.0K0.00%+6,508New
Cutler Group LP5,500$23.0K0.00%00.0%Unchanged
UBS Group AG2,609$11.0K0.00%−5,430−67.5%Reduced
Royal Bank of Canada2,174$9.00K0.00%−728−25.1%Reduced
Federation des caisses Desjardins du Quebec1,125$4.87K0.00%00.0%Unchanged
Capital Advisory Group Advisory Services, LLC1,000$4.00K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA493$2.13K0.00%−11,879−96.0%Reduced
Wells Fargo & Company502$2.00K0.00%−55,736−99.1%Reduced
New York State Common Retirement Fund257$1.00K0.00%−15,743−98.4%Reduced
Jacobi Capital Management LLC200$1.00K0.00%00.0%Unchanged
Quadrant Capital Group LLC336$1.00K0.00%+336New
Opaleye Management Inc.0$00.00%−1,250,000−100.0%Sold out
Nuveen Asset Management, LLC0$00.00%−110,831−100.0%Sold out
Altium Capital Management LP0$00.00%−89,930−100.0%Sold out
Russell Investments Group, Ltd.0$00.00%−53,464−100.0%Sold out
Ameriprise Financial Inc0$00.00%−48,385−100.0%Sold out
California State Teachers Retirement System0$00.00%−46,420−100.0%Sold out
Ci Investments Inc.0$00.00%−34,438−100.0%Sold out
Rhumbline Advisers0$00.00%−32,985−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−27,380−100.0%Sold out
AQR Capital Management LLC0$00.00%−23,909−100.0%Sold out
Manufacturers Life Insurance Company, The0$00.00%−20,520−100.0%Sold out
Engineers Gate Manager LP0$00.00%−18,100−100.0%Sold out
American International Group, Inc.0$00.00%−17,937−100.0%Sold out
Jacobs Levy Equity Management, Inc0$00.00%−16,464−100.0%Sold out
Man Group plc0$00.00%−15,600−100.0%Sold out
Invesco Ltd.0$00.00%−13,309−100.0%Sold out
Jane Street Group, LLC0$00.00%−11,529−100.0%Sold out
Voya Investment Management LLC0$00.00%−10,815−100.0%Sold out
Raymond James Trust N.A.0$00.00%−11,000−100.0%Sold out
STRS Ohio0$00.00%−6,700−100.0%Sold out
Citigroup Inc0$00.00%−4,864−100.0%Sold out
Panagora Asset Management Inc0$00.00%−4,333−100.0%Sold out
Lindbrook Capital, LLC0$00.00%−4,000−100.0%Sold out
Legal & General Group Plc0$00.00%−2,718−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−2,748−100.0%Sold out
Ameritas Investment Partners, Inc.0$00.00%−1,540−100.0%Sold out
Berman Capital Advisors, LLC0$00.00%−806−100.0%Sold out
Captrust Financial Advisors0$00.00%−596−100.0%Sold out
FMR LLC0$00.00%−83−100.0%Sold out
Ellevest, Inc.0$00.00%−4−100.0%Sold out