Gyre Therapeutics, Inc.
GYRE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001124105
No open-market purchases or sales by Gyre Therapeutics, Inc. insiders were filed in the last 90 days; 59 institutions reported holding it in 13F filings for Q2 2026, worth $57.1M in total; no superinvestor holds it.
13F holders, Q4 2021
Institutional positions in Gyre Therapeutics, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 51
- −15 vs. Q3 2021
- Shares held
- 15.0M
- −3.34M (−18.1%) vs. Q3 2021
- Total value
- $13.7M
- −$61.9M (−81.8%) vs. Q3 2021
- New holders
- 12
- 11 more added
- Sold out
- 27
- 15 more reduced
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GYRE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 59 | $57.1M |
| Q1 2026 | 56 | $23.8M |
| Q4 2025 | 44 | $23.6M |
| Q3 2025 | 48 | $23.1M |
| Q2 2025 | 48 | $25.1M |
| Q1 2025 | 46 | $20.1M |
| Q4 2024 | 41 | $21.6M |
| Q3 2024 | 37 | $20.2M |
| Q2 2024 | 30 | $15.0M |
| Q1 2024 | 21 | $14.3M |
| Q4 2023 | 16 | $15.6M |
| Q3 2023 | 32 | $1.04M |
| Q2 2023 | 29 | $796.3K |
| Q1 2023 | 40 | $707.6K |
| Q4 2022 | 35 | $2.63M |
| Q3 2022 | 35 | $3.90M |
| Q2 2022 | 41 | $14.2M |
| Q1 2022 | 43 | $6.39M |
| Q4 2021 | 51 | $13.7M |
| Q3 2021 | 66 | $75.7M |
| Q2 2021 | 69 | $87.7M |
| Q1 2021 | 89 | $113.0M |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Gyre Therapeutics, Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| JPMorgan Chase & Co | 49 | $0 | 0.00% | −31,058−99.8% | Reduced |
| Wells Fargo & Company | 479 | $0 | 0.00% | 00.0% | Unchanged |
| American Portfolios Advisors | 215 | $197 | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 464 | $424 | 0.00% | −73−13.6% | Reduced |
| Steward Partners Investment Advisory, LLC | 1,000 | $1.00K | 0.00% | −7,000−87.5% | Reduced |
| Simplex Trading, LLC | 2,294 | $2.00K | 0.00% | +2,294 | New |
| Cutler Group LP | 5,500 | $5.00K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 5,205 | $5.00K | 0.00% | +5,205 | New |
| Geneos Wealth Management Inc. | 8,214 | $7.00K | 0.00% | +8,214 | New |
| Commonwealth Equity Services, LLC | 10,000 | $9.00K | 0.00% | 00.0% | Unchanged |
| Colorado Capital Management, Inc. | 13,712 | $12.0K | 0.01% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 16,076 | $15.0K | 0.00% | +16,076 | New |
| Black Diamond Financial, LLC | 18,000 | $16.0K | 0.01% | −24,000−57.1% | Reduced |
| Jane Street Group, LLC | 17,379 | $16.0K | 0.00% | +17,379 | New |
| Bank of America Corp | 25,089 | $23.0K | 0.00% | −870−3.4% | Reduced |
| Stephens Inc | 29,185 | $27.0K | 0.00% | +12,350+73.4% | Added |
| Barclays PLC | 30,102 | $28.0K | 0.00% | −3,748−11.1% | Reduced |
| Citadel Advisors LLC | 31,516 | $29.0K | 0.00% | −33,893−51.8% | Reduced |
| Raymond James & Associates | 32,800 | $30.0K | 0.00% | −96,753−74.7% | Reduced |
| HSBC Holdings PLC | 32,528 | $30.0K | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 40,928 | $38.0K | 0.00% | +40,928 | New |
| Boothbay Fund Management, LLC | 45,915 | $42.0K | 0.00% | 00.0% | Unchanged |
| Virtu Financial LLC | 47,441 | $43.0K | 0.00% | +18,338+63.0% | Added |
| Johnson & Johnson | 66,951 | $61.0K | 0.01% | 00.0% | Unchanged |
| Marshall Wace, LLP | 67,605 | $61.0K | 0.00% | +67,605 | New |
| State Street Corp | 72,599 | $66.0K | 0.00% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 75,309 | $69.0K | 0.00% | 00.0% | Unchanged |
| Essex Woodlands Management, Inc. | 78,622 | $72.0K | 0.02% | 00.0% | Unchanged |
| CSS LLC | 88,656 | $81.0K | 0.00% | +55,107+164.3% | Added |
| Northern Trust Corp | 102,156 | $93.0K | 0.00% | −1,214−1.2% | Reduced |
| Kynam Capital Management, LP | 110,991 | $101.0K | 0.05% | +110,991 | New |
| RBF Capital, LLC | 132,396 | $121.0K | 0.01% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 140,186 | $128.0K | 0.00% | +140,186 | New |
| Gyon Technologies Capital Management, LP | 156,550 | $143.0K | 0.03% | +156,550 | New |
| Two Sigma Advisers, LP | 182,100 | $166.0K | 0.00% | +75,100+70.2% | Added |
| Acadian Asset Management LLC | 232,400 | $211.0K | 0.00% | +232,400 | New |
| Goldman Sachs Group Inc | 240,611 | $220.0K | 0.00% | +79,910+49.7% | Added |
| BlackRock Inc. | 257,284 | $235.0K | 0.00% | −13,434−5.0% | Reduced |
| Geode Capital Management, LLC | 286,585 | $261.0K | 0.00% | −64,956−18.5% | Reduced |
| Two Sigma Investments, LP | 308,552 | $282.0K | 0.00% | +254,483+470.7% | Added |
| Pura Vida Investments, LLC | 356,804 | $326.0K | 0.03% | −15,778−4.2% | Reduced |
| Ikarian Capital, LLC | 454,346 | $416.0K | 0.12% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 492,701 | $450.0K | 0.00% | −308,739−38.5% | Reduced |
| Assenagon Asset Management S.A. | 512,643 | $469.0K | 0.00% | +512,643 | New |
| Morgan Stanley | 514,228 | $470.0K | 0.00% | +436,148+558.6% | Added |
| Millennium Management LLC | 909,238 | $831.0K | 0.00% | +238,014+35.5% | Added |
| Sabby Management, LLC | 1,138,334 | $1.04M | 0.26% | +1,032,592+976.5% | Added |
| Vanguard Group Inc | 1,393,512 | $1.27M | 0.00% | −29,870−2.1% | Reduced |
| OrbiMed Advisors LLC | 1,729,402 | $1.58M | 0.02% | −982,198−36.2% | Reduced |
| Renaissance Technologies LLC | 1,771,908 | $1.62M | 0.00% | +1,732,123+4,353.7% | Added |
| Nantahala Capital Management, LLC | 2,761,660 | $2.52M | 0.16% | +329,448+13.5% | Added |
| Stonepine Capital Management, LLC | 0 | $0 | 0.00% | −2,635,014−100.0% | Sold out |
| 22NW, LP | 0 | $0 | 0.00% | −1,429,242−100.0% | Sold out |
| Ghost Tree Capital, LLC | 0 | $0 | 0.00% | −1,000,000−100.0% | Sold out |
| Sio Capital Management, LLC | 0 | $0 | 0.00% | −623,892−100.0% | Sold out |
| Acuta Capital Partners, LLC | 0 | $0 | 0.00% | −365,000−100.0% | Sold out |
| Bank of Montreal | 0 | $0 | 0.00% | −201,265−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −175,751−100.0% | Sold out |
| Parkman Healthcare Partners LLC | 0 | $0 | 0.00% | −133,449−100.0% | Sold out |
| AlphaCentric Advisors LLC | 0 | $0 | 0.00% | −114,000−100.0% | Sold out |
| Ergoteles LLC | 0 | $0 | 0.00% | −105,211−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −89,400−100.0% | Sold out |
| J. Goldman & Co LP | 0 | $0 | 0.00% | −60,755−100.0% | Sold out |
| Davenport & Co LLC | 0 | $0 | 0.00% | −59,400−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −53,788−100.0% | Sold out |
| Tocqueville Asset Management L.P. | 0 | $0 | 0.00% | −50,080−100.0% | Sold out |
| Raymond James Financial Services Advisors, Inc. | 0 | $0 | 0.00% | −49,812−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −40,520−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −25,527−100.0% | Sold out |
| PDT Partners, LLC | 0 | $0 | 0.00% | −21,563−100.0% | Sold out |
| Cherry Creek Investment Advisors, Inc. | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Kalos Management, Inc. | 0 | $0 | 0.00% | −16,710−100.0% | Sold out |
| Walleye Trading LLC | 0 | $0 | 0.00% | −13,507−100.0% | Sold out |
| Silverarc Capital Management, LLC | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Total Clarity Wealth Management, Inc. | 0 | $0 | 0.00% | −2,000−100.0% | Sold out |
| Capital Advisory Group Advisory Services, LLC | 0 | $0 | 0.00% | −1,000−100.0% | Sold out |
| Jacobi Capital Management LLC | 0 | $0 | 0.00% | −200−100.0% | Sold out |
| FMR LLC | 0 | $0 | 0.00% | −1−100.0% | Sold out |