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CytomX Therapeutics, Inc.

CTMX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001501989

No open-market purchases or sales by CytomX Therapeutics, Inc. insiders were filed in the last 90 days; 178 institutions reported holding it in 13F filings for Q2 2026, worth $799.0M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in CytomX Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
179
+58 vs. Q4 2025
Shares held
193.9M
+58.3M (+43.0%) vs. Q4 2025
Total value
$911.2M
+$333.5M (+57.7%) vs. Q4 2025
New holders
77
59 more added
Sold out
19
28 more reduced

1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CTMX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 179 institutions
Q1 2021: 126 institutionsQ2 2021: 122 institutionsQ3 2021: 114 institutionsQ4 2021: 110 institutionsQ1 2022: 119 institutionsQ2 2022: 99 institutionsQ3 2022: 84 institutionsQ4 2022: 81 institutionsQ1 2023: 76 institutionsQ2 2023: 67 institutionsQ3 2023: 62 institutionsQ4 2023: 68 institutionsQ1 2024: 88 institutionsQ2 2024: 74 institutionsQ3 2024: 69 institutionsQ4 2024: 70 institutionsQ1 2025: 66 institutionsQ2 2025: 83 institutionsQ3 2025: 103 institutionsQ4 2025: 122 institutionsQ1 2026: 179 institutionsQ2 2026: 178 institutions
Value heldQ1 2026: $911.2M
Q1 2021: $422.2MQ2 2021: $358.9MQ3 2021: $274.8MQ4 2021: $236.5MQ1 2022: $143.4MQ2 2022: $83.4MQ3 2022: $52.6MQ4 2022: $57.5MQ1 2023: $53.7MQ2 2023: $58.7MQ3 2023: $41.8MQ4 2023: $50.6MQ1 2024: $97.1MQ2 2024: $61.9MQ3 2024: $60.4MQ4 2024: $48.1MQ1 2025: $28.8MQ2 2025: $302.6MQ3 2025: $438.4MQ4 2025: $613.9MQ1 2026: $911.2MQ2 2026: $799.0M
Institutions holding CTMX and their total value by quarter
QuarterHoldersValue
Q2 2026178$799.0M
Q1 2026179$911.2M
Q4 2025122$613.9M
Q3 2025103$438.4M
Q2 202583$302.6M
Q1 202566$28.8M
Q4 202470$48.1M
Q3 202469$60.4M
Q2 202474$61.9M
Q1 202488$97.1M
Q4 202368$50.6M
Q3 202362$41.8M
Q2 202367$58.7M
Q1 202376$53.7M
Q4 202281$57.5M
Q3 202284$52.6M
Q2 202299$83.4M
Q1 2022119$143.4M
Q4 2021110$236.5M
Q3 2021114$274.8M
Q2 2021122$358.9M
Q1 2021126$422.2M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding CytomX Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding CTMX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Legal & General Group Plc141,893$666.9K0.00%+141,893New
Barclays PLC142,412$669.3K0.00%−194,113−57.7%Reduced
AWM Investment Company, Inc.150,000$705.0K0.08%+150,000New
Group One Trading, L.P.154,134$724.4K0.02%+154,134New
Y-Intercept (Hong Kong) Ltd167,514$787.3K0.01%+167,514New
UBS Asset Management Americas Inc189,400$890.2K0.00%+189,400New
Stonepine Capital Management, LLC200,000$940.0K0.83%+200,000New
Centiva Capital, LP200,000$940.0K0.04%+200,000New
Sphera Funds Management Ltd.220,000$1.03M0.18%+220,000New
Burkehill Global Management, LP225,000$1.06M0.05%+225,000New
Tema ETFs LLC227,505$1.07M0.07%+227,505New
DAFNA Capital Management LLC230,000$1.08M0.25%+230,000New
Scientech Research LLC230,598$1.08M0.90%+230,598New
LMR Partners LLP234,931$1.10M0.01%+234,931New
Rafferty Asset Management, LLC239,824$1.13M0.00%−33,760−12.3%Reduced
Squarepoint Ops LLC241,215$1.13M0.00%+191,318+383.4%Added
Toroso Investments, LLC245,768$1.16M0.00%+200,005+437.0%Added
SEI Investments Co248,248$1.17M0.00%+124,124+100.0%Added
Simplex Trading, LLC248,438$1.17M0.04%+224,387+933.0%Added
Brevan Howard Capital Management LP269,202$1.27M0.01%+257,798+2,260.6%Added
HighVista Strategies LLC288,057$1.35M0.37%+94,116+48.5%Added
Bank of New York Mellon Corp289,868$1.36M0.00%−38,380−11.7%Reduced
Soleus Capital Management, L.P.300,000$1.41M0.06%+300,000New
Swiss National Bank319,600$1.50M0.00%+319,600New
Seven Grand Managers, LLC325,000$1.53M0.10%+325,000New
Assenagon Asset Management S.A.364,173$1.71M0.00%−228,523−38.6%Reduced
Raymond James Financial Inc380,160$1.79M0.00%+63,189+19.9%Added
683 Capital Management, LLC425,000$2.00M0.19%+425,000New
Deutsche Bank AG463,421$2.18M0.00%+463,421New
Schulhoff & Co Inc477,550$2.24M0.92%+102,700+27.4%Added
Morgan Stanley520,495$2.45M0.00%+119,304+29.7%Added
Exome Asset Management LLC521,468$2.45M1.44%−223,837−30.0%Reduced
Velan Capital Investment Management LP540,000$2.54M1.59%+460,000+575.0%Added
Longaeva Partners L.P.550,000$2.58M0.12%+550,000New
EAM Investors, LLC565,113$2.66M0.31%+361,290+177.3%Added
First Trust Advisors LP568,562$2.67M0.00%+145,394+34.4%Added
Caption Management, LLC573,224$2.69M0.13%+573,224New
Ensign Peak Advisors, Inc592,473$2.78M0.01%+592,473New
BNP Paribas Arbitrage, SA606,275$2.85M0.00%+603,450+21,361.1%Added
Northern Trust Corp612,141$2.88M0.00%+196,963+47.4%Added
DV Trading LLC714,000$3.36M0.30%+714,000New
Balyasny Asset Management LLC730,844$3.43M0.01%−3,141,358−81.1%Reduced
Vanguard Portfolio Management LLC794,755$3.74M0.00%+794,755New
Trexquant Investment LP898,767$4.22M0.03%+898,767New
Eventide Asset Management, LLC900,000$4.23M0.07%+900,000New
Ally Bridge Group (NY) LLC900,000$4.23M4.20%+900,000New
Jane Street Group, LLC997,510$4.69M0.01%+390,292+64.3%Added
Seven Fleet Capital Management LP1,085,398$5.10M1.60%+1,036,500+2,119.7%Added
Patient Square Capital LP1,085,790$5.10M0.91%+1,085,790New
Vanguard Fiduciary Trust Co1,102,883$5.18M0.00%+1,102,883New
Gilder Gagnon Howe & Co LLC1,120,309$5.27M0.06%+1,120,309New
Goldman Sachs Group Inc1,459,839$6.86M0.00%−1,001,105−40.7%Reduced
Susquehanna International Group, LLP1,869,615$8.79M0.01%+888,017+90.5%Added
Dimensional Fund Advisors LP1,930,920$9.07M0.00%+641,264+49.7%Added
Woodline Partners LP2,000,825$9.40M0.04%−336,180−14.4%Reduced
Geode Capital Management, LLC2,066,612$9.72M0.00%+540,946+35.5%Added
Qube Research & Technologies Ltd2,249,583$10.6M0.02%+1,188,455+112.0%Added
Two Sigma Investments, LP2,710,156$12.7M0.01%+1,149,401+73.6%Added
Jefferies Financial Group Inc.3,067,864$14.4M0.18%+3,044,100+12,809.7%Added
UBS Group AG3,120,155$14.7M0.00%+2,749,416+741.6%Added
Eversept Partners, LP3,188,514$15.0M0.99%+681,424+27.2%Added
ADAR1 Capital Management, LLC3,410,190$16.0M0.96%−772,579−18.5%Reduced
Siren, L.L.C.3,457,711$16.3M0.45%+3,457,711New
Wellington Management Group LLP3,582,985$16.8M0.00%+3,582,985New
Millennium Management LLC3,660,190$17.2M0.01%+3,370,537+1,163.6%Added
Marshall Wace, LLP4,138,176$19.4M0.02%+2,981,240+257.7%Added
Nextech Invest, Ltd.4,449,932$20.9M1.47%+4,449,932New
Elmind Capital, LP4,550,000$21.4M6.07%+3,850,000+550.0%Added
Baker Bros. Advisors LP4,975,826$23.4M0.13%+725,000+17.1%Added
BlackRock, Inc.5,228,280$24.6M0.00%+1,558,887+42.5%Added
Citadel Advisors LLC5,406,193$25.4M0.02%+5,063,889+1,479.4%Added
State Street Corp5,663,408$26.6M0.00%+522,477+10.2%Added
Point72 Asset Management, L.P.7,875,390$37.0M0.06%+2,685,852+51.8%Added
Vanguard Capital Management LLC8,733,118$41.0M0.00%+8,733,118New
VR Adviser, LLC9,982,124$46.9M1.75%−5,579,376−35.9%Reduced
Perceptive Advisors LLC10,098,824$47.5M0.94%+418,639+4.3%Added
Bank of America Corp10,202,785$48.0M0.00%+9,326,480+1,064.3%Added
Kynam Capital Management, LP15,013,093$70.6M4.48%+6,047,016+67.4%Added
FMR LLC31,955,637$150.2M0.01%+7,267,528+29.4%Added
Commodore Capital LP0$00.00%−7,692,300−100.0%Sold out
Financial Engines Advisors L.L.C.0$00.00%−3,828,717−100.0%Sold out
OrbiMed Advisors LLC0$00.00%−3,525,650−100.0%Sold out
Ikarian Capital, LLC0$00.00%−3,172,616−100.0%Sold out
Vivo Capital, LLC0$00.00%−2,884,615−100.0%Sold out
StemPoint Capital LP0$00.00%−1,036,311−100.0%Sold out
Silverarc Capital Management, LLC0$00.00%−385,974−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−335,524−100.0%Sold out
HRT Financial LP0$00.00%−71,867−100.0%Sold out
SG Americas Securities, LLC0$00.00%−53,109−100.0%Sold out
Timothy G. Youngquist 2020 Irrevocable Trust0$00.00%−51,155−100.0%Sold out
Baader Bank INC0$00.00%−45,000−100.0%Sold out
Lighthouse Investment Partners, LLC0$00.00%−32,040−100.0%Sold out
Cambria Investment Management, L.P.0$00.00%−31,332−100.0%Sold out
Empowered Funds, LLC0$00.00%−31,332−100.0%Sold out
Twinbeech Capital LP0$00.00%−17,600−100.0%Sold out
Bank of Nova Scotia0$00.00%−13,661−100.0%Sold out
HSBC Holdings PLC0$00.00%−12,230−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−564−100.0%Sold out
Vanguard Group Inc––––Not filed