Caris Life Sciences, Inc.
CAI- Exchange
- Nasdaq
- Industry
- Services-Medical Laboratories
- SEC CIK
- 0002019410
In the last 90 days, Caris Life Sciences, Inc. insiders filed 1 open-market purchase and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $2.75B in total; superinvestors Coatue Management and Duquesne Family Office hold it.
13F holders, Q1 2026
Institutional positions in Caris Life Sciences, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 202
- +22 vs. Q4 2025
- Shares held
- 156.9M
- +11.7M (+8.1%) vs. Q4 2025
- Total value
- $2.80B
- −$1.11B (−28.4%) vs. Q4 2025
- New holders
- 57
- 88 more added
- Sold out
- 35
- 38 more reduced
6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CAI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 247 | $2.75B |
| Q1 2026 | 202 | $2.80B |
| Q4 2025 | 186 | $3.92B |
| Q3 2025 | 138 | $3.41B |
| Q2 2025 | 116 | $2.92B |
| Q1 2025 | 0 | $0 |
| Q4 2024 | 0 | $0 |
| Q3 2024 | 0 | $0 |
| Q2 2024 | 0 | $0 |
| Q1 2024 | 0 | $0 |
| Q4 2023 | 0 | $0 |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Caris Life Sciences, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Charles Schwab Investment Management Inc | 25,331 | $452.9K | 0.00% | +25,331 | New |
| Oak Ridge Investments LLC | 26,106 | $466.8K | 0.03% | +4,286+19.6% | Added |
| Public Employees Retirement System of Ohio | 26,519 | $474.2K | 0.00% | +19,698+288.8% | Added |
| Dimensional Fund Advisors LP | 27,492 | $491.6K | 0.00% | +27,492 | New |
| Park Avenue Securities LLC | 27,937 | $500.0K | 0.00% | +27,937 | New |
| Legal & General Group Plc | 28,781 | $514.6K | 0.00% | +21,900+318.3% | Added |
| AQR Capital Management LLC | 28,994 | $518.4K | 0.00% | +28,994 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 30,350 | $542.7K | 0.00% | +193+0.6% | Added |
| Diversified Trust Co | 32,500 | $581.1K | 0.01% | +12,500+62.5% | Added |
| Caption Management, LLC | 33,332 | $596.0K | 0.03% | −17,556−34.5% | Reduced |
| Nikko Asset Management Americas, Inc. | 36,133 | $646.1K | 0.01% | −18,586−34.0% | Reduced |
| Deutsche Bank AG | 38,290 | $684.6K | 0.00% | +13,000+51.4% | Added |
| Americana Partners, LLC | 38,367 | $686.0K | 0.02% | +25,934+208.6% | Added |
| Treasurer of the State of North Carolina | 39,005 | $697.0K | 0.00% | +29,509+310.8% | Added |
| Police & Firemen's Retirement System of New Jersey | 39,497 | $706.2K | 0.01% | +27,565+231.0% | Added |
| Entropy Technologies, LP | 40,503 | $724.2K | 0.03% | +40,503 | New |
| CastleKnight Management LP | 41,036 | $733.7K | 0.03% | +30,600+293.2% | Added |
| LPL Financial LLC | 42,041 | $751.7K | 0.00% | +16,330+63.5% | Added |
| Dark Forest Capital Management LP | 43,080 | $770.3K | 0.07% | −35,083−44.9% | Reduced |
| Franklin Resources Inc | 44,975 | $804.2K | 0.00% | −223,640−83.3% | Reduced |
| New York State Common Retirement Fund | 45,700 | $817.1K | 0.00% | +32,800+254.3% | Added |
| Renaissance Capital LLC | 43,484 | $826.2K | 0.60% | +29,055+201.4% | Added |
| China Universal Asset Management Co., Ltd. | 50,069 | $895.2K | 0.07% | +4,093+8.9% | Added |
| Natixis | 52,778 | $943.7K | 0.00% | +52,778 | New |
| Susquehanna International Group, LLP | 53,066 | $948.8K | 0.00% | +53,066 | New |
| Envestnet Asset Management Inc | 53,607 | $958.5K | 0.00% | +22,578+72.8% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 56,744 | $1.01M | 0.00% | −18,586−24.7% | Reduced |
| Twinbeech Capital LP | 58,100 | $1.04M | 0.11% | +58,100 | New |
| Barclays PLC | 74,423 | $1.33M | 0.00% | +20,306+37.5% | Added |
| Rhumbline Advisers | 74,622 | $1.33M | 0.00% | +51,241+219.2% | Added |
| Burkehill Global Management, LP | 75,000 | $1.34M | 0.07% | 00.0% | Unchanged |
| Citigroup Inc | 77,180 | $1.38M | 0.00% | +46,455+151.2% | Added |
| Citadel Advisors LLC | 77,810 | $1.39M | 0.00% | −3,036,146−97.5% | Reduced |
| Creative Planning | 77,998 | $1.39M | 0.00% | −71,858−48.0% | Reduced |
| XTX Topco Ltd | 78,506 | $1.40M | 0.02% | +78,506 | New |
| Alliancebernstein L.P. | 57,076 | $1.54M | 0.00% | +36,689+180.0% | Added |
| Smartleaf Asset Management LLC | 94,051 | $1.58M | 0.06% | +94,051 | New |
| Pura Vida Investments, LLC | 89,940 | $1.61M | 10.81% | 00.0% | Unchanged |
| Raymond James Financial Inc | 90,233 | $1.61M | 0.00% | −7,285−7.5% | Reduced |
| Vanguard Fiduciary Trust Co | 96,581 | $1.73M | 0.00% | +96,581 | New |
| Tudor Investment Corp Et Al | 100,327 | $1.79M | 0.01% | −82,055−45.0% | Reduced |
| Engineers Gate Manager LP | 102,757 | $1.84M | 0.02% | +31,354+43.9% | Added |
| Oddo BHF Asset Management SAS | 109,539 | $1.96M | 0.08% | −52,774−32.5% | Reduced |
| Man Group plc | 128,971 | $2.31M | 0.00% | +128,971 | New |
| D. E. Shaw & Co., Inc. | 129,577 | $2.32M | 0.00% | +129,577 | New |
| State of Wisconsin Investment Board | 136,334 | $2.44M | 0.01% | −13,666−9.1% | Reduced |
| Aquatic Capital Management LLC | 140,097 | $2.50M | 0.07% | +136,280+3,570.3% | Added |
| Quantinno Capital Management LP | 140,909 | $2.52M | 0.00% | +75,987+117.0% | Added |
| Manufacturers Life Insurance Company, The | 153,512 | $2.74M | 0.00% | +51,696+50.8% | Added |
| Northern Trust Corp | 174,065 | $3.11M | 0.00% | +137,117+371.1% | Added |
| Qube Research & Technologies Ltd | 187,480 | $3.35M | 0.00% | −19,513−9.4% | Reduced |
| Worldquant Millennium Advisors LLC | 194,710 | $3.48M | 0.01% | +5,849+3.1% | Added |
| Arrowstreet Capital, Limited Partnership | 210,593 | $3.77M | 0.00% | +210,593 | New |
| Parkman Healthcare Partners LLC | 229,912 | $4.11M | 0.43% | +104,912+83.9% | Added |
| Bank of New York Mellon Corp | 231,661 | $4.14M | 0.00% | +181,258+359.6% | Added |
| Federated Hermes, Inc. | 239,150 | $4.28M | 0.01% | +236,150+7,871.7% | Added |
| Ghisallo Capital Management LLC | 250,000 | $4.47M | 0.12% | −595,332−70.4% | Reduced |
| Massachusetts Financial Services Co | 267,950 | $4.79M | 0.00% | −673,689−71.5% | Reduced |
| Picton Mahoney Asset Management | 278,977 | $4.99M | 0.05% | +60,672+27.8% | Added |
| Lazard Asset Management LLC | 305,911 | $5.47M | 0.01% | +63,132+26.0% | Added |
| Ameriprise Financial Inc | 408,079 | $7.30M | 0.00% | −1,097,001−72.9% | Reduced |
| Goldman Sachs Group Inc | 410,340 | $7.34M | 0.00% | +60,198+17.2% | Added |
| Renaissance Technologies LLC | 449,900 | $8.04M | 0.01% | +120,000+36.4% | Added |
| Trexquant Investment LP | 490,536 | $8.77M | 0.06% | +407,831+493.1% | Added |
| Bank of America Corp | 523,268 | $9.36M | 0.00% | −599,480−53.4% | Reduced |
| Rock Springs Capital Management LP | 563,000 | $10.1M | 0.59% | −124,500−18.1% | Reduced |
| SEI Investments Co | 598,712 | $10.7M | 0.01% | +574,261+2,348.6% | Added |
| Zevenbergen Capital Investments LLC | 610,233 | $10.9M | 0.31% | +67,048+12.3% | Added |
| Nuveen, LLC | 663,578 | $11.9M | 0.00% | +641,165+2,860.7% | Added |
| TD Asset Management Inc | 670,388 | $12.0M | 0.01% | −103,464−13.4% | Reduced |
| Woodline Partners LP | 723,163 | $12.9M | 0.05% | 00.0% | Unchanged |
| Gotham Asset Management, LLC | 744,426 | $13.3M | 0.04% | +677,240+1,008.0% | Added |
| Geode Capital Management, LLC | 778,532 | $13.9M | 0.00% | +405,553+108.7% | Added |
| Point72 Asset Management, L.P. | 918,331 | $16.4M | 0.03% | −946,529−50.8% | Reduced |
| State Street Corp | 984,953 | $17.6M | 0.00% | +724,308+277.9% | Added |
| Morgan Stanley | 1,079,417 | $19.3M | 0.00% | −715,574−39.9% | Reduced |
| UBS Asset Management Americas Inc | 1,149,133 | $20.5M | 0.00% | −321,162−21.8% | Reduced |
| Capital World Investors | 1,180,173 | $21.1M | 0.00% | +1,180,173 | New |
| Champlain Investment Partners, LLC | 1,207,963 | $21.6M | 0.27% | +268,598+28.6% | Added |
| Invesco Ltd. | 1,222,278 | $21.9M | 0.00% | +189,163+18.3% | Added |
| Canada Pension Plan Investment Board | 1,322,752 | $23.7M | 0.02% | −141,806−9.7% | Reduced |
| Millennium Management LLC | 1,527,756 | $27.3M | 0.02% | −2,124,891−58.2% | Reduced |
| FIL Ltd | 1,546,091 | $27.6M | 0.02% | +423,316+37.7% | Added |
| Clearbridge Investments, LLC | 1,551,774 | $27.7M | 0.02% | +135,567+9.6% | Added |
| BNP Paribas Arbitrage, SA | 1,614,286 | $28.9M | 0.02% | +928,460+135.4% | Added |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 1,894,450 | $33.9M | 1.15% | +1,894,450 | New |
| Los Angeles Capital Management LLC | 2,289,602 | $40.9M | 0.16% | +2,289,037+405,139.3% | Added |
| UBS Group AG | 2,745,811 | $49.1M | 0.01% | +561,831+25.7% | Added |
| OrbiMed Advisors LLC | 2,806,811 | $50.2M | 1.14% | −309,200−9.9% | Reduced |
| JPMorgan Chase & Co | 3,460,215 | $58.3M | 0.00% | +1,014,934+41.5% | Added |
| Vanguard Capital Management LLC | 3,329,021 | $59.5M | 0.00% | +3,329,021 | New |
| Neuberger Berman Group LLC | 3,590,586 | $64.2M | 0.05% | −210,336−5.5% | Reduced |
| Vanguard Portfolio Management LLC | 3,758,462 | $67.2M | 0.00% | +3,758,462 | New |
| Price T Rowe Associates Inc | 4,371,771 | $78.2M | 0.01% | −456,194−9.4% | Reduced |
| BlackRock, Inc. | 4,857,112 | $86.8M | 0.00% | +2,485,876+104.8% | Added |
| T. Rowe Price Investment Management, Inc. | 5,588,257 | $99.9M | 0.07% | −3,617,702−39.3% | Reduced |
| PointState Capital LP | 7,360,446 | $131.6M | 3.06% | +641,739+9.6% | Added |
| Braidwell LP | 8,009,447 | $143.2M | 4.78% | +193,305+2.5% | Added |
| Coatue Management LLCSuperinvestorCoatue Management | 9,819,992 | $175.6M | 0.60% | 00.0% | Unchanged |
| Sixth Street Partners Management Company, L.P. | 14,385,399 | $257.2M | 36.19% | −5,000,000−25.8% | Reduced |