Caris Life Sciences, Inc.
CAI- Exchange
- Nasdaq
- Industry
- Services-Medical Laboratories
- SEC CIK
- 0002019410
In the last 90 days, Caris Life Sciences, Inc. insiders filed 1 open-market purchase and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $2.75B in total; superinvestors Coatue Management and Duquesne Family Office hold it.
13F holders, Q4 2025
Institutional positions in Caris Life Sciences, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 186
- +50 vs. Q3 2025
- Shares held
- 145.3M
- +32.6M (+29.0%) vs. Q3 2025
- Total value
- $3.92B
- +$531.3M (+15.7%) vs. Q3 2025
- New holders
- 77
- 63 more added
- Sold out
- 27
- 30 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CAI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 247 | $2.75B |
| Q1 2026 | 202 | $2.80B |
| Q4 2025 | 186 | $3.92B |
| Q3 2025 | 138 | $3.41B |
| Q2 2025 | 116 | $2.92B |
| Q1 2025 | 0 | $0 |
| Q4 2024 | 0 | $0 |
| Q3 2024 | 0 | $0 |
| Q2 2024 | 0 | $0 |
| Q1 2024 | 0 | $0 |
| Q4 2023 | 0 | $0 |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Caris Life Sciences, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Park Avenue Securities LLC | 0 | $0 | 0.00% | −20,730−100.0% | Sold out |
| Ieq Capital, LLC | 0 | $0 | 0.00% | −17,141−100.0% | Sold out |
| Man Group plc | 0 | $0 | 0.00% | −16,078−100.0% | Sold out |
| Harbor Investment Advisory, LLC | 0 | $0 | 0.00% | −15,650−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −8,200−100.0% | Sold out |
| American Century Companies Inc | 0 | $0 | 0.00% | −6,865−100.0% | Sold out |
| SummitTX Capital, L.P. | 0 | $0 | 0.00% | −6,736−100.0% | Sold out |
| Wealthcare Advisory Partners LLC | 0 | $0 | 0.00% | −6,666−100.0% | Sold out |
| Nomura Asset Management Co Ltd | 0 | $0 | 0.00% | −562−100.0% | Sold out |
| Caitong International Asset Management Co., Ltd | 0 | $0 | 0.00% | −208−100.0% | Sold out |
| Massmutual Trust Co FSB | 0 | $0 | 0.00% | −5−100.0% | Sold out |
| Tortoise Investment Management, LLC | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Rakuten Investment Management, Inc. | 0 | $0 | 0.00% | −14,518−100.0% | Sold out |
| Point72 (DIFC) Ltd | – | – | – | – | Not filed |
| Cubist Systematic Strategies, LLC | – | – | – | – | Not filed |