Caris Life Sciences, Inc.
CAI- Exchange
- Nasdaq
- Industry
- Services-Medical Laboratories
- SEC CIK
- 0002019410
In the last 90 days, Caris Life Sciences, Inc. insiders filed 1 open-market purchase and 3 sales; 247 institutions reported holding it in 13F filings for Q2 2026, worth $2.75B in total; superinvestors Coatue Management and Duquesne Family Office hold it.
13F holders, Q4 2025
Institutional positions in Caris Life Sciences, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 186
- +50 vs. Q3 2025
- Shares held
- 145.3M
- +32.6M (+29.0%) vs. Q3 2025
- Total value
- $3.92B
- +$531.3M (+15.7%) vs. Q3 2025
- New holders
- 77
- 63 more added
- Sold out
- 27
- 30 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CAI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 247 | $2.75B |
| Q1 2026 | 202 | $2.80B |
| Q4 2025 | 186 | $3.92B |
| Q3 2025 | 138 | $3.41B |
| Q2 2025 | 116 | $2.92B |
| Q1 2025 | 0 | $0 |
| Q4 2024 | 0 | $0 |
| Q3 2024 | 0 | $0 |
| Q2 2024 | 0 | $0 |
| Q1 2024 | 0 | $0 |
| Q4 2023 | 0 | $0 |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Caris Life Sciences, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Envestnet Asset Management Inc | 31,029 | $837.2K | 0.00% | +31,029 | New |
| Vanguard Group Inc | 33,505 | $904.0K | 0.00% | −142,039−80.9% | Reduced |
| Voloridge Investment Management, LLC | 35,050 | $945.6K | 0.00% | +35,050 | New |
| Northern Trust Corp | 36,948 | $996.9K | 0.00% | −8,647−19.0% | Reduced |
| Maven Securities LTD | 40,000 | $1.08M | 0.14% | +40,000 | New |
| VARCOV Co. | 40,037 | $1.08M | 0.43% | +40,037 | New |
| Mangrove Partners | 42,483 | $1.15M | 0.09% | +42,483 | New |
| China Universal Asset Management Co., Ltd. | 45,976 | $1.24M | 0.10% | +45,976 | New |
| Element Capital Management LLC | 50,000 | $1.35M | 0.70% | +50,000 | New |
| Bank of New York Mellon Corp | 50,403 | $1.36M | 0.00% | +25,534+102.7% | Added |
| Caption Management, LLC | 50,888 | $1.37M | 0.06% | +50,888 | New |
| Barclays PLC | 54,117 | $1.46M | 0.00% | +50,940+1,603.4% | Added |
| Nikko Asset Management Americas, Inc. | 54,719 | $1.48M | 0.02% | +7,348+15.5% | Added |
| Hamilton Lane Advisors LLC | 58,725 | $1.58M | 0.87% | +58,725 | New |
| Squarepoint Ops LLC | 64,397 | $1.74M | 0.00% | +64,397 | New |
| Quantinno Capital Management LP | 64,922 | $1.75M | 0.00% | −7,301−10.1% | Reduced |
| Gotham Asset Management, LLC | 67,186 | $1.81M | 0.01% | +33,983+102.3% | Added |
| Engineers Gate Manager LP | 71,403 | $1.93M | 0.02% | +49,375+224.1% | Added |
| Burkehill Global Management, LP | 75,000 | $2.02M | 0.13% | 00.0% | Unchanged |
| Sumitomo Mitsui Trust Holdings, Inc. | 75,330 | $2.03M | 0.00% | +15,778+26.5% | Added |
| Dark Forest Capital Management LP | 78,163 | $2.11M | 0.10% | +46,506+146.9% | Added |
| Trexquant Investment LP | 82,705 | $2.23M | 0.02% | +82,705 | New |
| Pura Vida Investments, LLC | 89,940 | $2.43M | 9.07% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 92,653 | $2.50M | 0.02% | +92,653 | New |
| Raymond James Financial Inc | 97,518 | $2.63M | 0.00% | +2,630+2.8% | Added |
| Manufacturers Life Insurance Company, The | 101,816 | $2.78M | 0.00% | −8,268−7.5% | Reduced |
| Jump Financial, LLC | 103,005 | $2.78M | 0.03% | +103,005 | New |
| Norges Bank | 110,294 | $2.98M | 0.00% | +110,294 | New |
| HRT Financial LP | 122,939 | $3.32M | 0.01% | +122,939 | New |
| Parkman Healthcare Partners LLC | 125,000 | $3.37M | 0.32% | +125,000 | New |
| Creative Planning | 149,856 | $4.04M | 0.00% | +149,856 | New |
| State of Wisconsin Investment Board | 150,000 | $4.05M | 0.01% | 00.0% | Unchanged |
| Oddo BHF Asset Management SAS | 162,313 | $4.38M | 0.16% | +162,313 | New |
| Walleye Capital LLC | 162,915 | $4.40M | 0.03% | −157,754−49.2% | Reduced |
| Jane Street Group, LLC | 170,997 | $4.61M | 0.01% | +156,402+1,071.6% | Added |
| Tudor Investment Corp Et Al | 182,382 | $4.92M | 0.03% | −82,169−31.1% | Reduced |
| Worldquant Millennium Advisors LLC | 188,861 | $5.10M | 0.02% | +178,769+1,771.4% | Added |
| Qube Research & Technologies Ltd | 206,993 | $5.58M | 0.01% | +174,241+532.0% | Added |
| Picton Mahoney Asset Management | 218,305 | $5.89M | 0.06% | +212,095+3,415.4% | Added |
| Holocene Advisors, LP | 237,897 | $6.42M | 0.01% | +66,770+39.0% | Added |
| Lazard Asset Management LLC | 242,779 | $6.55M | 0.01% | −34,758−12.5% | Reduced |
| Schonfeld Strategic Advisors LLC | 247,407 | $6.68M | 0.03% | +247,407 | New |
| State Street Corp | 260,645 | $7.03M | 0.00% | +105,305+67.8% | Added |
| Franklin Resources Inc | 268,615 | $7.25M | 0.00% | +51,651+23.8% | Added |
| Meridiem Capital Partners LP | 278,063 | $7.50M | 0.47% | +278,063 | New |
| Renaissance Technologies LLC | 329,900 | $8.90M | 0.01% | +104,800+46.6% | Added |
| Goldman Sachs Group Inc | 350,142 | $9.45M | 0.00% | +67,933+24.1% | Added |
| Geode Capital Management, LLC | 372,979 | $10.1M | 0.00% | −25,349−6.4% | Reduced |
| ARK Investment Management LLCSuperinvestorARK Invest | 408,725 | $11.0M | 0.07% | +163,375+66.6% | Added |
| Seven Grand Managers, LLC | 495,095 | $13.4M | 1.02% | +395,095+395.1% | Added |
| Zevenbergen Capital Investments LLC | 543,185 | $14.7M | 0.33% | +543,185 | New |
| BNP Paribas Arbitrage, SA | 685,826 | $18.5M | 0.01% | +684,626+57,052.2% | Added |
| Rock Springs Capital Management LP | 687,500 | $18.5M | 0.95% | −106,151−13.4% | Reduced |
| Woodline Partners LP | 723,163 | $19.5M | 0.08% | 00.0% | Unchanged |
| TD Asset Management Inc | 773,852 | $20.9M | 0.02% | +551,516+248.1% | Added |
| Ghisallo Capital Management LLC | 845,332 | $22.8M | 1.02% | −202,831−19.4% | Reduced |
| Champlain Investment Partners, LLC | 939,365 | $25.3M | 0.26% | +939,365 | New |
| Massachusetts Financial Services Co | 941,639 | $25.4M | 0.01% | −29,691−3.1% | Reduced |
| Marshall Wace, LLP | 1,002,734 | $27.1M | 0.03% | +919,759+1,108.5% | Added |
| Invesco Ltd. | 1,033,115 | $27.9M | 0.00% | +229,313+28.5% | Added |
| Bank of America Corp | 1,122,748 | $30.3M | 0.00% | +693,270+161.4% | Added |
| FIL Ltd | 1,122,775 | $30.3M | 0.02% | +896,855+397.0% | Added |
| Perceptive Advisors LLC | 1,136,206 | $30.7M | 0.56% | +38,043+3.5% | Added |
| Clearbridge Investments, LLC | 1,416,207 | $38.2M | 0.03% | +34,977+2.5% | Added |
| Canada Pension Plan Investment Board | 1,464,558 | $39.5M | 0.03% | +141,806+10.7% | Added |
| UBS Asset Management Americas Inc | 1,470,295 | $39.7M | 0.01% | +354,104+31.7% | Added |
| Ameriprise Financial Inc | 1,505,080 | $40.6M | 0.01% | −174,388−10.4% | Reduced |
| Longaeva Partners L.P. | 1,509,745 | $40.7M | 4.84% | +223,777+17.4% | Added |
| Balyasny Asset Management LLC | 1,660,280 | $44.8M | 0.08% | +1,653,363+23,902.9% | Added |
| Morgan Stanley | 1,794,991 | $48.4M | 0.00% | +260,568+17.0% | Added |
| Point72 Asset Management, L.P. | 1,864,860 | $50.3M | 0.08% | +1,618,236+656.2% | Added |
| UBS Group AG | 2,183,980 | $58.9M | 0.01% | +1,948,107+825.9% | Added |
| BlackRock, Inc. | 2,371,236 | $64.0M | 0.00% | +1,724,155+266.5% | Added |
| JPMorgan Chase & Co | 2,445,281 | $66.0M | 0.00% | +1,587,176+185.0% | Added |
| Citadel Advisors LLC | 3,113,956 | $84.0M | 0.06% | +3,113,956 | New |
| OrbiMed Advisors LLC | 3,116,011 | $84.1M | 1.72% | +81,153+2.7% | Added |
| Millennium Management LLC | 3,652,647 | $98.5M | 0.07% | −285,425−7.2% | Reduced |
| Neuberger Berman Group LLC | 3,800,922 | $102.5M | 0.08% | −544,120−12.5% | Reduced |
| Price T Rowe Associates Inc | 4,827,965 | $130.3M | 0.01% | −2,096,780−30.3% | Reduced |
| PointState Capital LP | 6,718,707 | $181.3M | 3.10% | +2,834,986+73.0% | Added |
| Braidwell LP | 7,816,142 | $210.9M | 6.74% | +500,000+6.8% | Added |
| T. Rowe Price Investment Management, Inc. | 9,205,959 | $248.4M | 0.16% | +1,180,200+14.7% | Added |
| Coatue Management LLCSuperinvestorCoatue Management | 9,819,992 | $264.9M | 0.66% | −322,206−3.2% | Reduced |
| FMR LLC | 14,217,768 | $383.6M | 0.02% | +4,584,333+47.6% | Added |
| Sixth Street Partners Management Company, L.P. | 19,385,399 | $523.0M | 53.72% | −5,000,000−20.5% | Reduced |
| J. H. Whitney Equity Partners VI, LLC | 20,256,615 | $546.5M | 100.00% | +20,256,615 | New |
| Silver Lake Group, L.L.C. | 0 | $0 | 0.00% | −5,291,006−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −1,101,071−100.0% | Sold out |
| Lord, Abbett & Co. LLC | 0 | $0 | 0.00% | −850,000−100.0% | Sold out |
| Janus Henderson Group PLC | 0 | $0 | 0.00% | −664,438−100.0% | Sold out |
| First Light Asset Management, LLC | 0 | $0 | 0.00% | −403,924−100.0% | Sold out |
| Freestone Grove Partners LP | 0 | $0 | 0.00% | −251,389−100.0% | Sold out |
| Jennison Associates LLC | 0 | $0 | 0.00% | −84,459−100.0% | Sold out |
| Soros Fund Management LLCSuperinvestorSoros Fund Management | 0 | $0 | 0.00% | −55,650−100.0% | Sold out |
| SRS Investment Management, LLC | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| D. E. Shaw & Co., Inc. | 0 | $0 | 0.00% | −49,785−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −30,910−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −28,988−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −28,081−100.0% | Sold out |
| Atika Capital Management LLC | 0 | $0 | 0.00% | −25,000−100.0% | Sold out |