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Annexon, Inc.

ANNX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001528115

In the last 90 days, Annexon, Inc. insiders filed 1 open-market purchase and 0 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $1.02B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Annexon, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
216
+3 vs. Q1 2026
Shares held
178.4M
+22.5M (+14.4%) vs. Q1 2026
Total value
$1.02B
+$155.2M (+18.0%) vs. Q1 2026
New holders
31
79 more added
Sold out
28
80 more reduced

4 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANNX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 216 institutions
Q1 2021: 72 institutionsQ2 2021: 74 institutionsQ3 2021: 82 institutionsQ4 2021: 97 institutionsQ1 2022: 100 institutionsQ2 2022: 78 institutionsQ3 2022: 72 institutionsQ4 2022: 84 institutionsQ1 2023: 100 institutionsQ2 2023: 95 institutionsQ3 2023: 93 institutionsQ4 2023: 99 institutionsQ1 2024: 127 institutionsQ2 2024: 140 institutionsQ3 2024: 142 institutionsQ4 2024: 153 institutionsQ1 2025: 148 institutionsQ2 2025: 129 institutionsQ3 2025: 144 institutionsQ4 2025: 168 institutionsQ1 2026: 217 institutionsQ2 2026: 216 institutions
Value heldQ2 2026: $1.02B
Q1 2021: $1.04BQ2 2021: $873.7MQ3 2021: $708.6MQ4 2021: $445.7MQ1 2022: $105.9MQ2 2022: $144.9MQ3 2022: $292.3MQ4 2022: $243.3MQ1 2023: $207.6MQ2 2023: $190.0MQ3 2023: $126.0MQ4 2023: $365.7MQ1 2024: $679.4MQ2 2024: $526.9MQ3 2024: $651.8MQ4 2024: $574.6MQ1 2025: $192.1MQ2 2025: $238.7MQ3 2025: $309.2MQ4 2025: $687.2MQ1 2026: $863.7MQ2 2026: $1.02B
Institutions holding ANNX and their total value by quarter
QuarterHoldersValue
Q2 2026216$1.02B
Q1 2026217$863.7M
Q4 2025168$687.2M
Q3 2025144$309.2M
Q2 2025129$238.7M
Q1 2025148$192.1M
Q4 2024153$574.6M
Q3 2024142$651.8M
Q2 2024140$526.9M
Q1 2024127$679.4M
Q4 202399$365.7M
Q3 202393$126.0M
Q2 202395$190.0M
Q1 2023100$207.6M
Q4 202284$243.3M
Q3 202272$292.3M
Q2 202278$144.9M
Q1 2022100$105.9M
Q4 202197$445.7M
Q3 202182$708.6M
Q2 202174$873.7M
Q1 202172$1.04B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Annexon, Inc.; share changes are against Q1 2026.

Institutions holding ANNX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Great Point Partners LLC3,500,000$20.0M4.71%+1,000,000+40.0%Added
Ameriprise Financial Inc3,509,623$20.0M0.00%+60,502+1.8%Added
MPM Oncology Impact Management LP3,544,354$20.2M1.23%+3,544,354New
Geode Capital Management, LLC4,037,193$23.1M0.00%+659,370+19.5%Added
Bellevue Group AG4,100,016$23.4M0.49%−1,057,274−20.5%Reduced
Bain Capital Life Sciences Investors, LLC4,437,731$25.3M1.51%−774,943−14.9%Reduced
Siren, L.L.C.4,458,646$25.5M0.52%+500,000+12.6%Added
Goldman Sachs Group Inc5,825,579$33.3M0.00%+3,672,699+170.6%Added
Mak Capital One LLC5,862,180$33.5M4.69%+1,138,137+24.1%Added
Vanguard Capital Management LLC6,871,015$39.2M0.00%+914,426+15.4%Added
Woodline Partners LP6,925,067$39.5M0.12%+4,587,930+196.3%Added
BVF Inc8,698,173$49.7M1.27%00.0%Unchanged
State Street Corp9,824,321$56.1M0.00%+2,905,066+42.0%Added
Redmile Group, LLC11,869,877$67.8M4.55%−2,679,891−18.4%Reduced
BlackRock, Inc.13,539,744$77.3M0.00%+2,601,235+23.8%Added
FMR LLC19,518,496$111.5M0.00%+8,882,848+83.5%Added
Longaeva Partners L.P.0$00.00%−620,401−100.0%Sold out
Silverarc Capital Management, LLC0$00.00%−496,461−100.0%Sold out
Rosalind Advisors, Inc.0$00.00%−200,000−100.0%Sold out
Algert Global LLC0$00.00%−154,840−100.0%Sold out
Man Group plc0$00.00%−109,222−100.0%Sold out
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−92,707−100.0%Sold out
Polen Capital Management LLC0$00.00%−70,152−100.0%Sold out
Axq Capital, LP0$00.00%−58,185−100.0%Sold out
ADAR1 Capital Management, LLC0$00.00%−55,000−100.0%Sold out
BIT Capital GmbH0$00.00%−50,000−100.0%Sold out
Jane Street Group, LLC0$00.00%−47,120−100.0%Sold out
Mirabella Financial Services LLP0$00.00%−28,739−100.0%Sold out
Virtu Financial LLC0$00.00%−28,450−100.0%Sold out
TD Asset Management Inc0$00.00%−22,760−100.0%Sold out
Scientech Research LLC0$00.00%−17,316−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−14,938−100.0%Sold out
Vontobel Holding Ltd.0$00.00%−14,511−100.0%Sold out
Magnetar Financial LLC0$00.00%−14,205−100.0%Sold out
American Century Companies Inc0$00.00%−12,463−100.0%Sold out
nVerses Capital, LLC0$00.00%−11,897−100.0%Sold out
Abel Hall, LLC0$00.00%−10,921−100.0%Sold out
Integrated Wealth Concepts LLC0$00.00%−10,232−100.0%Sold out
MAI Capital Management0$00.00%−795−100.0%Sold out
Federated Hermes, Inc.0$00.00%−753−100.0%Sold out
Root Financial Partners, LLC0$00.00%−94−100.0%Sold out
US Bancorp0$00.00%−77−100.0%Sold out
Advisory Services Network, LLC0$00.00%−23−100.0%Sold out
JPL Wealth Management, LLC0$00.00%−13−100.0%Sold out
Janus Henderson Group PLC––––Not filed
CWM, LLC––––Not filed
Trask Adam Roland––––Not filed
Sunbelt Securities, Inc.––––Not filed