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Agios Pharmaceuticals, Inc.

AGIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001439222

In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 2 sales; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Agios Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
234
−1 vs. Q4 2025
Shares held
63.1M
+7.41M (+13.3%) vs. Q4 2025
Total value
$2.12B
+$605.4M (+40.0%) vs. Q4 2025
New holders
36
82 more added
Sold out
37
82 more reduced

3 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AGIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 234 institutions
Q1 2021: 175 institutionsQ2 2021: 186 institutionsQ3 2021: 165 institutionsQ4 2021: 161 institutionsQ1 2022: 161 institutionsQ2 2022: 157 institutionsQ3 2022: 168 institutionsQ4 2022: 160 institutionsQ1 2023: 165 institutionsQ2 2023: 153 institutionsQ3 2023: 146 institutionsQ4 2023: 170 institutionsQ1 2024: 187 institutionsQ2 2024: 206 institutionsQ3 2024: 208 institutionsQ4 2024: 225 institutionsQ1 2025: 221 institutionsQ2 2025: 216 institutionsQ3 2025: 221 institutionsQ4 2025: 238 institutionsQ1 2026: 234 institutionsQ2 2026: 238 institutions
Value heldQ1 2026: $2.12B
Q1 2021: $3.37BQ2 2021: $3.63BQ3 2021: $2.81BQ4 2021: $1.95BQ1 2022: $1.74BQ2 2022: $1.31BQ3 2022: $1.64BQ4 2022: $1.67BQ1 2023: $1.36BQ2 2023: $1.68BQ3 2023: $1.46BQ4 2023: $1.33BQ1 2024: $1.81BQ2 2024: $2.51BQ3 2024: $2.58BQ4 2024: $1.97BQ1 2025: $1.76BQ2 2025: $2.05BQ3 2025: $2.55BQ4 2025: $1.67BQ1 2026: $2.12BQ2 2026: $2.45B
Institutions holding AGIO and their total value by quarter
QuarterHoldersValue
Q2 2026238$2.45B
Q1 2026234$2.12B
Q4 2025238$1.67B
Q3 2025221$2.55B
Q2 2025216$2.05B
Q1 2025221$1.76B
Q4 2024225$1.97B
Q3 2024208$2.58B
Q2 2024206$2.51B
Q1 2024187$1.81B
Q4 2023170$1.33B
Q3 2023146$1.46B
Q2 2023153$1.68B
Q1 2023165$1.36B
Q4 2022160$1.67B
Q3 2022168$1.64B
Q2 2022157$1.31B
Q1 2022161$1.74B
Q4 2021161$1.95B
Q3 2021165$2.81B
Q2 2021186$3.63B
Q1 2021175$3.37B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Agios Pharmaceuticals, Inc.; share changes are against Q4 2025.

Institutions holding AGIO in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Marshall Wace, LLP448,118$15.2M0.02%+94,479+26.7%Added
Vestal Point Capital, LP450,000$15.2M0.43%+125,000+38.5%Added
Connor, Clark & Lunn Investment Management Ltd.450,093$15.2M0.04%−112,549−20.0%Reduced
Charles Schwab Investment Management Inc477,032$16.1M0.00%−5,590−1.2%Reduced
Artisan Partners Limited Partnership481,516$16.3M0.03%−22,969−4.6%Reduced
Bank of America Corp507,900$17.2M0.00%−31,441−5.8%Reduced
Northern Trust Corp509,272$17.2M0.00%−2,629−0.5%Reduced
Foresite Capital Management VI LLC525,000$17.8M3.86%−5,000−0.9%Reduced
SCS Capital Management LLC612,850$20.7M0.22%+14,085+2.4%Added
Citadel Advisors LLC619,613$21.0M0.01%−729,355−54.1%Reduced
Wellington Management Group LLP641,486$21.7M0.00%+43,660+7.3%Added
Jane Street Group, LLC685,240$23.2M0.02%−435,810−38.9%Reduced
Nuveen, LLC722,348$24.4M0.01%+424,440+142.5%Added
Rock Springs Capital Management LP799,163$27.0M1.59%00.0%Unchanged
Goldman Sachs Group Inc805,776$27.3M0.00%−228,198−22.1%Reduced
Morgan Stanley967,525$32.7M0.00%+73,488+8.2%Added
Dimensional Fund Advisors LP1,151,614$38.9M0.01%+147,273+14.7%Added
GW&K Investment Management, LLC1,214,901$41.1M0.36%+7,600+0.6%Added
Frazier Life Sciences Management, L.P.1,256,080$42.5M1.09%−23,674−1.8%Reduced
MPM Oncology Impact Management LP1,306,261$44.2M3.41%+2,888+0.2%Added
Susquehanna International Group, LLP1,344,953$45.5M0.06%+202,521+17.7%Added
Geode Capital Management, LLC1,467,910$49.7M0.00%+54,372+3.8%Added
T. Rowe Price Investment Management, Inc.1,488,740$50.4M0.03%+1,487,848+166,799.1%Added
Nomura Asset Management International Inc.1,494,435$50.6M0.09%−206,974−12.2%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,580,840$53.5M0.06%+220,110+16.2%Added
Erste Asset Management GmbH2,704,900$80.1M0.74%−100,000−3.6%Reduced
Vanguard Portfolio Management LLC2,611,035$88.3M0.00%+2,611,035New
Lynx1 Capital Management LP2,611,568$88.3M13.96%+2,531,944+3,179.9%Added
Vanguard Capital Management LLC2,632,316$89.1M0.00%+2,632,316New
D. E. Shaw & Co., Inc.2,681,169$90.7M0.07%+843,983+45.9%Added
Armistice Capital, LLC2,716,000$91.9M3.03%−320,000−10.5%Reduced
State Street Corp3,364,879$113.7M0.00%+256,734+8.3%Added
Farallon Capital Management, L.L.C.5,684,000$192.3M1.14%+524,495+10.2%Added
BlackRock, Inc.5,754,957$194.7M0.00%+519,528+9.9%Added
TCG Crossover Management, LLC0$00.00%−1,181,841−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−200,000−100.0%Sold out
Moore Capital Management, LP0$00.00%−150,000−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−147,950−100.0%Sold out
HighVista Strategies LLC0$00.00%−147,662−100.0%Sold out
Ikarian Capital, LLC0$00.00%−115,489−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−85,200−100.0%Sold out
First Trust Advisors LP0$00.00%−78,656−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−71,146−100.0%Sold out
DekaBank Deutsche Girozentrale0$00.00%−40,000−100.0%Sold out
Schroder Investment Management Group0$00.00%−46,242−100.0%Sold out
Freestone Grove Partners LP0$00.00%−40,841−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−37,291−100.0%Sold out
Quadrature Capital Ltd0$00.00%−35,857−100.0%Sold out
Jump Financial, LLC0$00.00%−33,052−100.0%Sold out
Ishara Investments LP0$00.00%−30,000−100.0%Sold out
Aigen Investment Management, LP0$00.00%−25,915−100.0%Sold out
Entropy Technologies, LP0$00.00%−19,163−100.0%Sold out
VARCOV Co.0$00.00%−19,104−100.0%Sold out
Winton Group Ltd0$00.00%−16,751−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−12,567−100.0%Sold out
Quest Partners LLC0$00.00%−11,963−100.0%Sold out
Capstone Investment Advisors, LLC0$00.00%−10,355−100.0%Sold out
STRS Ohio0$00.00%−10,000−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−9,198−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−8,226−100.0%Sold out
Griffin Asset Management, Inc.0$00.00%−7,382−100.0%Sold out
Contravisory Investment Management, Inc.0$00.00%−6,189−100.0%Sold out
Quarry LP0$00.00%−3,000−100.0%Sold out
Amalgamated Bank0$00.00%−1,774−100.0%Sold out
Torren Management, LLC0$00.00%−615−100.0%Sold out
Quantbot Technologies LP0$00.00%−386−100.0%Sold out
Aspect Partners, LLC0$00.00%−361−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−204−100.0%Sold out
Concord Wealth Partners0$00.00%−200−100.0%Sold out
Brown Brothers Harriman & Co0$00.00%−144−100.0%Sold out
SageView Advisory Group, LLC0$00.00%−10−100.0%Sold out
Vanguard Group Inc––––Not filed
Comerica Bank––––Not filed
Global Retirement Partners, LLC––––Not filed