Agios Pharmaceuticals, Inc.
AGIO- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001439222
In the last 90 days, Agios Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 1 sale; 238 institutions reported holding it in 13F filings for Q2 2026, worth $2.45B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Agios Pharmaceuticals, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 221
- +8 vs. Q2 2025
- Shares held
- 63.5M
- +1.82M (+3.0%) vs. Q2 2025
- Total value
- $2.55B
- +$494.7M (+24.1%) vs. Q2 2025
- New holders
- 42
- 69 more added
- Sold out
- 34
- 69 more reduced
3 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AGIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 238 | $2.45B |
| Q1 2026 | 234 | $2.12B |
| Q4 2025 | 238 | $1.67B |
| Q3 2025 | 221 | $2.55B |
| Q2 2025 | 216 | $2.05B |
| Q1 2025 | 221 | $1.76B |
| Q4 2024 | 225 | $1.97B |
| Q3 2024 | 208 | $2.58B |
| Q2 2024 | 206 | $2.51B |
| Q1 2024 | 187 | $1.81B |
| Q4 2023 | 170 | $1.33B |
| Q3 2023 | 146 | $1.46B |
| Q2 2023 | 153 | $1.68B |
| Q1 2023 | 165 | $1.36B |
| Q4 2022 | 160 | $1.67B |
| Q3 2022 | 168 | $1.64B |
| Q2 2022 | 157 | $1.31B |
| Q1 2022 | 161 | $1.74B |
| Q4 2021 | 161 | $1.95B |
| Q3 2021 | 165 | $2.81B |
| Q2 2021 | 186 | $3.63B |
| Q1 2021 | 175 | $3.37B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Agios Pharmaceuticals, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Atria Investments LLC | 13,386 | $537.3K | 0.01% | −87−0.6% | Reduced |
| Teacher Retirement System of Texas | 13,484 | $541.2K | 0.00% | −1,921−12.5% | Reduced |
| Two Sigma Advisers, LP | 13,600 | $545.9K | 0.00% | +13,600 | New |
| BNP Paribas Arbitrage, SA | 14,698 | $590.0K | 0.00% | +2,790+23.4% | Added |
| Toroso Investments, LLC | 14,914 | $598.6K | 0.00% | −646−4.2% | Reduced |
| Profund Advisors LLC | 15,109 | $606.5K | 0.02% | +4,258+39.2% | Added |
| Freestone Grove Partners LP | 15,424 | $619.1K | 0.00% | +15,424 | New |
| Police & Firemen's Retirement System of New Jersey | 15,633 | $627.5K | 0.01% | +2,710+21.0% | Added |
| State Board of Administration of Florida Retirement System | 15,847 | $636.1K | 0.00% | 00.0% | Unchanged |
| Guggenheim Capital LLC | 15,902 | $638.3K | 0.00% | −2,002−11.2% | Reduced |
| Rockefeller Capital Management L.P. | 16,038 | $643.8K | 0.00% | +16,038 | New |
| Arizona State Retirement System | 16,255 | $652.5K | 0.00% | −421−2.5% | Reduced |
| Winton Group Ltd | 16,400 | $658.3K | 0.02% | +16,400 | New |
| Caption Management, LLC | 17,494 | $702.2K | 0.04% | +494+2.9% | Added |
| Royal Bank of Canada | 17,527 | $705.0K | 0.00% | −5,637−24.3% | Reduced |
| Handelsbanken Fonder AB | 19,323 | $776.0K | 0.00% | 00.0% | Unchanged |
| Great West Life Assurance Co | 20,325 | $796.0K | 0.00% | +662+3.4% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 20,476 | $821.9K | 0.00% | +4,080+24.9% | Added |
| FMR LLC | 20,712 | $831.4K | 0.00% | +2,120+11.4% | Added |
| Intech Investment Management LLC | 23,578 | $946.4K | 0.01% | +785+3.4% | Added |
| Janus Henderson Group PLC | 23,797 | $955.3K | 0.00% | 00.0% | Unchanged |
| Kennedy Capital Management, Inc. | 24,641 | $989.1K | 0.02% | −12,064−32.9% | Reduced |
| Oak Ridge Investments LLC | 25,385 | $1.02M | 0.07% | −11,867−31.9% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 25,501 | $1.02M | 0.04% | +10,496+70.0% | Added |
| Alps Advisors Inc | 27,554 | $1.11M | 0.01% | −3,720−11.9% | Reduced |
| SG Americas Securities, LLC | 27,650 | $1.11M | 0.00% | +27,650 | New |
| Victory Capital Management Inc | 30,232 | $1.21M | 0.00% | +818+2.8% | Added |
| SEI Investments Co | 32,300 | $1.30M | 0.00% | +21,974+212.8% | Added |
| MetLife Investment Management | 34,032 | $1.37M | 0.01% | 00.0% | Unchanged |
| Harbor Capital Advisors, Inc. | 34,835 | $1.40M | 0.11% | −2,189−5.9% | Reduced |
| Edgewood Management LLC | 35,000 | $1.40M | 0.00% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 35,573 | $1.43M | 0.00% | −23,527−39.8% | Reduced |
| Algert Global LLC | 35,770 | $1.44M | 0.02% | −53,060−59.7% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 36,592 | $1.47M | 0.00% | −2,987−7.5% | Reduced |
| ADAR1 Capital Management, LLC | 37,000 | $1.49M | 0.15% | +1,100+3.1% | Added |
| Ameriprise Financial Inc | 38,428 | $1.54M | 0.00% | −13,824−26.5% | Reduced |
| DekaBank Deutsche Girozentrale | 40,000 | $1.56M | 0.00% | 00.0% | Unchanged |
| Virginia Retirement Systems Et Al | 41,061 | $1.65M | 0.01% | −8,600−17.3% | Reduced |
| Citigroup Inc | 43,620 | $1.75M | 0.00% | −12,869−22.8% | Reduced |
| Wells Fargo & Company | 44,754 | $1.80M | 0.00% | +7,060+18.7% | Added |
| Phocas Financial Corp. | 46,608 | $1.87M | 0.24% | +46,608 | New |
| New York State Common Retirement Fund | 49,790 | $2.00M | 0.00% | +10,697+27.4% | Added |
| Moore Capital Management, LP | 55,000 | $2.21M | 0.04% | −25,000−31.3% | Reduced |
| Two Sigma Investments, LP | 59,629 | $2.39M | 0.00% | +59,629 | New |
| California State Teachers Retirement System | 61,296 | $2.46M | 0.00% | +13,637+28.6% | Added |
| Alliancebernstein L.P. | 61,503 | $2.47M | 0.00% | +33+0.1% | Added |
| Assenagon Asset Management S.A. | 67,153 | $2.70M | 0.00% | +67,153 | New |
| Rafferty Asset Management, LLC | 68,220 | $2.74M | 0.01% | +18,817+38.1% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 71,213 | $2.86M | 0.00% | +15,929+28.8% | Added |
| Woodline Partners LP | 73,996 | $2.97M | 0.01% | −159,072−68.3% | Reduced |
| First Trust Advisors LP | 74,429 | $2.99M | 0.00% | +38,002+104.3% | Added |
| Rhumbline Advisers | 87,702 | $3.52M | 0.00% | −2,179−2.4% | Reduced |
| Jump Financial, LLC | 87,900 | $3.53M | 0.04% | +87,900 | New |
| AQR Capital Management LLC | 91,635 | $3.61M | 0.00% | −5,261−5.4% | Reduced |
| Manufacturers Life Insurance Company, The | 96,012 | $3.85M | 0.00% | −36,071−27.3% | Reduced |
| Prudential Financial Inc | 98,239 | $3.94M | 0.00% | −60,120−38.0% | Reduced |
| Nantahala Capital Management, LLC | 100,000 | $4.01M | 0.25% | +100,000 | New |
| Parkman Healthcare Partners LLC | 100,380 | $4.03M | 0.44% | +100,380 | New |
| Swiss National Bank | 106,660 | $4.28M | 0.00% | −2,800−2.6% | Reduced |
| UBS Asset Management Americas Inc | 106,875 | $4.29M | 0.00% | −110,527−50.8% | Reduced |
| Nuveen, LLC | 119,580 | $4.80M | 0.00% | 00.0% | Unchanged |
| Hudson Bay Capital Management LP | 122,500 | $4.92M | 0.03% | −7,500−5.8% | Reduced |
| Invesco Ltd. | 126,976 | $5.10M | 0.00% | +14,359+12.8% | Added |
| Ikarian Capital, LLC | 126,979 | $5.10M | 1.16% | +126,979 | New |
| Vestal Point Capital, LP | 127,000 | $5.10M | 0.23% | +127,000 | New |
| TD Asset Management Inc | 128,294 | $5.15M | 0.00% | −39,900−23.7% | Reduced |
| Patient Square Capital LP | 133,827 | $5.37M | 1.44% | −5,905−4.2% | Reduced |
| American Century Companies Inc | 145,121 | $5.83M | 0.00% | +17,474+13.7% | Added |
| Alyeska Investment Group, L.P. | 146,514 | $5.88M | 0.02% | +146,514 | New |
| Allianz Asset Management GmbH | 146,643 | $5.89M | 0.01% | +7,745+5.6% | Added |
| Peregrine Capital Management LLC | 162,905 | $6.54M | 0.20% | +162,905 | New |
| AXA Investment Managers S.A. | 177,675 | $7.13M | 0.02% | +177,675 | New |
| JPMorgan Chase & Co | 183,100 | $7.35M | 0.00% | −844,317−82.2% | Reduced |
| Baker Bros. Advisors LP | 189,866 | $7.62M | 0.06% | 00.0% | Unchanged |
| HighVista Strategies LLC | 195,298 | $7.84M | 1.92% | +125,171+178.5% | Added |
| Barclays PLC | 216,040 | $8.67M | 0.00% | +35,336+19.6% | Added |
| Marshall Wace, LLP | 226,824 | $9.10M | 0.01% | −457,845−66.9% | Reduced |
| UBS Group AG | 242,813 | $9.75M | 0.00% | +123,979+104.3% | Added |
| Eagle Health Investments LP | 246,230 | $9.88M | 2.59% | −84,600−25.6% | Reduced |
| SummitTX Capital, L.P. | 262,977 | $10.6M | 0.44% | +262,977 | New |
| Palo Alto Investors LP | 265,497 | $10.7M | 1.97% | −3,286−1.2% | Reduced |
| Pictet Asset Management Holding SA | 272,161 | $10.7M | 0.01% | −22,579−7.7% | Reduced |
| Bank of New York Mellon Corp | 270,096 | $10.8M | 0.00% | +3,442+1.3% | Added |
| Legal & General Group Plc | 322,934 | $13.0M | 0.00% | +258,629+402.2% | Added |
| D. E. Shaw & Co., Inc. | 367,749 | $14.8M | 0.01% | −228,453−38.3% | Reduced |
| Jane Street Group, LLC | 395,120 | $15.9M | 0.02% | +361,631+1,079.9% | Added |
| Artisan Partners Limited Partnership | 402,943 | $16.2M | 0.02% | +12,959+3.3% | Added |
| Morgan Stanley | 416,998 | $16.7M | 0.00% | +125,033+42.8% | Added |
| Charles Schwab Investment Management Inc | 482,186 | $19.4M | 0.00% | +6,145+1.3% | Added |
| Citadel Advisors LLC | 491,982 | $19.7M | 0.02% | −589,488−54.5% | Reduced |
| Boothbay Fund Management, LLC | 495,341 | $19.9M | 0.51% | +48,322+10.8% | Added |
| Balyasny Asset Management LLC | 495,491 | $19.9M | 0.04% | +495,491 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 530,098 | $21.3M | 0.07% | +24,873+4.9% | Added |
| Northern Trust Corp | 555,410 | $22.3M | 0.00% | −1,395−0.3% | Reduced |
| SCS Capital Management LLC | 598,765 | $24.0M | 0.26% | −5,320−0.9% | Reduced |
| ArrowMark Colorado Holdings LLC | 679,922 | $27.3M | 0.51% | +21,231+3.2% | Added |
| Armistice Capital, LLC | 764,000 | $30.7M | 0.96% | −404,000−34.6% | Reduced |
| Adage Capital Partners GP, L.L.C. | 800,000 | $32.1M | 0.05% | +9,000+1.1% | Added |
| Goldman Sachs Group Inc | 804,766 | $32.3M | 0.00% | +156,705+24.2% | Added |
| GW&K Investment Management, LLC | 852,942 | $34.2M | 0.30% | −15,676−1.8% | Reduced |