Perceptive Advisors LLC
- SEC CIK
- 0001224962
- Latest filing
- Aug 14, 2026
Holdings in Q2 2026
Holdings as of Jun 30, 2026, filed Aug 14, 2026. Long positions only; changes compare share counts with Q1 2026.
- Positions
- 102
- +10 vs. Q1 2026
- Portfolio value
- $6.44B
- +$1.38B (+27.2%) vs. Q1 2026
| Security | Class | Shares | Value | % of portfolio | Share change | Action | History |
|---|---|---|---|---|---|---|---|
| PRAXPraxis Precision Medicines, Inc. | COM NEW | 2,035,986 | $681.6M | 10.6% | 00.0% | Unchanged | History |
| SYRESpyre Therapeutics, Inc. | COM NEW | 4,319,496 | $383.5M | 6.0% | +536,271+14.2% | Added | History |
| CELCCelcuity Inc. | COM | 3,197,200 | $334.5M | 5.2% | +70,000+2.2% | Added | History |
| ASNDAscendis Pharma A/S | ORD SHS | 1,163,721 | $310.4M | 4.8% | −367,700−24.0% | Reduced | History |
| RYTMRhythm Pharmaceuticals, Inc. | COM | 2,586,295 | $287.2M | 4.5% | +212,500+9.0% | Added | History |
| ROIVRoivant Sciences Ltd. | SHS | 8,085,461 | $286.1M | 4.4% | −200,000−2.4% | Reduced | History |
| RLAYRelay Therapeutics, Inc. | COM | 14,106,187 | $263.9M | 4.1% | +4,355,046+44.7% | Added | History |
| TVTXTravere Therapeutics, Inc. | COM | 3,752,574 | $213.2M | 3.3% | −389,977−9.4% | Reduced | History |
| KARDKardigan, Inc. | COM | 8,200,662 | $195.6M | 3.0% | +8,200,662 | New | History |
| NUVLNuvalent, Inc. | COM | 1,580,505 | $195.2M | 3.0% | 00.0% | Unchanged | History |
| EWTXEdgewise Therapeutics, Inc. | COM | 4,373,974 | $177.7M | 2.8% | −50,000−1.1% | Reduced | History |
| APGEApogee Therapeutics, Inc. | COM | 1,308,113 | $173.6M | 2.7% | −232,271−15.1% | Reduced | History |
| AMLXAmylyx Pharmaceuticals, Inc. | COM | 8,334,882 | $149.7M | 2.3% | +50,000+0.6% | Added | History |
| MGTXMeiraGTx Holdings plc | COM | 10,786,658 | $145.7M | 2.3% | +460,555+4.5% | Added | History |
| ORKAOruka Therapeutics, Inc. | COM | 1,345,063 | $128.0M | 2.0% | −50,438−3.6% | Reduced | History |
| INBXInhibrx Biosciences, Inc. | COM | 1,297,763 | $123.0M | 1.9% | −144,944−10.0% | Reduced | History |
| PTGXProtagonist Therapeutics, Inc | COM | 981,879 | $120.4M | 1.9% | −249,000−20.2% | Reduced | History |
| SLDBSolid Biosciences Inc. | COM NEW | 11,906,646 | $118.9M | 1.8% | 00.0% | Unchanged | History |
| ZYMEZymeworks Inc. | COM | 4,182,953 | $109.3M | 1.7% | +672,875+19.2% | Added | History |
| TNGXTango Therapeutics, Inc. | COM | 3,377,000 | $105.6M | 1.6% | +2,568,847+317.9% | Added | History |
| IMTXImmatics N.V. | SHS | 10,383,456 | $105.2M | 1.6% | 00.0% | Unchanged | History |
| NRIXNurix Therapeutics, Inc. | COM | 4,320,422 | $104.8M | 1.6% | +609,545+16.4% | Added | History |
| BCRXBiocryst Pharmaceuticals Inc | COM | 10,308,888 | $103.1M | 1.6% | +2,874,855+38.7% | Added | History |
| RVMDRevolution Medicines, Inc. | COM | 527,600 | $98.8M | 1.5% | +269,000+104.0% | Added | History |
| AVLNAvalyn Pharma Inc. | COM SHS | 2,675,296 | $88.1M | 1.4% | +2,675,296 | New | History |
| DYNDyne Therapeutics, Inc. | COM | 2,689,235 | $59.7M | 0.9% | −1,979,604−42.4% | Reduced | History |
| BIIBBiogen Inc. | COM | 276,173 | $59.7M | 0.9% | +276,173 | New | History |
| IMVTImmunovant, Inc. | COM | 1,357,383 | $52.3M | 0.8% | −240,000−15.0% | Reduced | History |
| UNHUnitedHealth Group Inc | Stock | 116,806 | $48.5M | 0.8% | +116,806 | New | History |
| IONSIonis Pharmaceuticals Inc | COM | 566,000 | $44.9M | 0.7% | +62,000+12.3% | Added | History |
| STROSutro Biopharma, Inc. | COM SHS | 1,304,846 | $43.3M | 0.7% | +589,539+82.4% | Added | History |
| ANROAlto Neuroscience, Inc. | COM SHS | 1,609,893 | $42.5M | 0.7% | −400,000−19.9% | Reduced | History |
| JAZZJazz Pharmaceuticals plc | SHS USD | 170,000 | $41.0M | 0.6% | 00.0% | Unchanged | History |
| CRVSCorvus Pharmaceuticals, Inc. | COM | 2,667,441 | $39.9M | 0.6% | +375,000+16.4% | Added | History |
| SIONSionna Therapeutics, Inc. | COM | 905,000 | $39.8M | 0.6% | +246,561+37.4% | Added | History |
| CTMXCytomX Therapeutics, Inc. | COM | 10,439,185 | $39.1M | 0.6% | +340,361+3.4% | Added | History |
| AORTArtivion, Inc. | COM | 1,737,290 | $39.0M | 0.6% | +100,000+6.1% | Added | History |
| XFORX4 Pharmaceuticals, Inc | COM NEW | 7,933,491 | $37.0M | 0.6% | +1,195,843+17.7% | Added | History |
| CORTCorcept Therapeutics Inc | COM | 398,385 | $34.6M | 0.5% | +348,385+696.8% | Added | History |
| RGENRepligen Corp | COM | 248,212 | $33.9M | 0.5% | −32,329−11.5% | Reduced | History |
| AVRAnteris Technologies Global Corp. | COM | 3,425,476 | $33.7M | 0.5% | 00.0% | Unchanged | History |
| RAPPRapport Therapeutics, Inc. | COM | 773,342 | $32.2M | 0.5% | +99,419+14.8% | Added | History |
| DMRADamora Therapeutics, Inc. | COM NEW | 1,223,000 | $31.8M | 0.5% | 00.0% | Unchanged | History |
| CRLCharles River Laboratories International, Inc. | COM | 140,000 | $31.8M | 0.5% | +140,000 | New | History |
| AXSMAxsome Therapeutics, Inc. | COM | 118,450 | $29.0M | 0.5% | −31,500−21.0% | Reduced | History |
| DBVTDBV Technologies S.A. | SPONSORED ADS | 1,653,350 | $27.1M | 0.4% | +688,959+71.4% | Added | History |
| IRTCiRhythm Holdings, Inc. | COM | 223,766 | $26.6M | 0.4% | +118,740+113.1% | Added | History |
| ADPTAdaptive Biotechnologies Corp | COM | 1,217,325 | $26.1M | 0.4% | +1,064,825+698.2% | Added | History |
| SABSSAB Biotherapeutics, Inc. | COM NEW | 6,627,501 | $25.8M | 0.4% | +195,758+3.0% | Added | History |
| DHRDanaher Corp | Stock | 130,000 | $24.8M | 0.4% | +130,000 | New | History |
| TENXTenax Therapeutics, Inc. | COM NEW | 1,700,000 | $24.7M | 0.4% | +252,218+17.4% | Added | History |
| NAUTNautilus Biotechnology, Inc. | COM | 11,634,211 | $21.8M | 0.3% | −960,000−7.6% | Reduced | History |
| OBIOOrchestra BioMed Holdings, Inc. | COM | 5,037,906 | $21.7M | 0.3% | 00.0% | Unchanged | History |
| ISRGIntuitive Surgical Inc | COM NEW | 51,884 | $20.6M | 0.3% | −33,535−39.3% | Reduced | History |
| ANLAdlai Nortye Group Ltd. | ADS | 1,793,190 | $20.6M | 0.3% | +1,793,190 | New | History |
| CTNMContineum Therapeutics, Inc. | CL A | 1,255,592 | $20.6M | 0.3% | 00.0% | Unchanged | History |
| NVCTNuvectis Pharma, Inc. | COM | 1,000,000 | $18.4M | 0.3% | +1,000,000 | New | History |
| PALIPalisade Bio, Inc. | COM | 8,425,065 | $17.6M | 0.3% | −503,084−5.6% | Reduced | History |
| OMDAOmada Health, Inc. | COM | 786,330 | $17.3M | 0.3% | 00.0% | Unchanged | History |
| LONALeonaBio, Inc. | COM | 1,859,322 | $17.1M | 0.3% | 00.0% | Unchanged | History |
| EOLSEvolus, Inc. | COM | 2,459,285 | $17.1M | 0.3% | +1,172,423+91.1% | Added | History |
| IVVDInvivyd, Inc. | COM | 18,490,636 | $16.1M | 0.3% | −2,368,667−11.4% | Reduced | History |
| Celcuity Inc.15102KAA8 | NOTE 2.750% 8/0 | – | $14.6M | 0.2% | – | – | – |
| MIRMMirum Pharmaceuticals, Inc. | COM | 115,391 | $13.5M | 0.2% | +115,391 | New | History |
| SRZNSurrozen, Inc. | COM NEW | 503,985 | $13.1M | 0.2% | +274,592+119.7% | Added | History |
| BBNXBeta Bionics, Inc. | COM | 832,944 | $13.1M | 0.2% | −10,000−1.2% | Reduced | History |
| AXGNAxogen, Inc. | COM | 247,312 | $11.4M | 0.2% | −450,000−64.5% | Reduced | History |
| OSCROscar Health, Inc. | CL A | 400,000 | $11.4M | 0.2% | +400,000 | New | History |
| OCSOculis Holding AG | ORDINARY SHARES | 808,827 | $11.2M | 0.2% | +315,000+63.8% | Added | History |
| SPTXSeaport Therapeutics, Inc. | COMMON STOCK | 500,000 | $10.9M | 0.2% | +500,000 | New | History |
| VRDNViridian Therapeutics, Inc. | COM | 581,980 | $10.7M | 0.2% | −588,849−50.3% | Reduced | History |
| BSXBoston Scientific Corp | Stock | 250,000 | $10.7M | 0.2% | +250,000 | New | History |
| BLLNBillionToOne, Inc. | CL A | 86,812 | $10.4M | 0.2% | −5,000−5.4% | Reduced | History |
| ABVXAbivax S.A. | SPONSORED ADS | 74,000 | $9.86M | 0.2% | −254,884−77.5% | Reduced | History |
| NTRANatera, Inc. | COM | 34,689 | $9.42M | 0.1% | +34,689 | New | History |
| ENGNenGene Therapeutics Inc. | COM | 4,822,169 | $8.34M | 0.1% | −1,005,337−17.3% | Reduced | History |
| RACCResearch Alliance Corp III | ORD SHS CL A | 750,000 | $8.03M | 0.1% | +750,000 | New | History |
| AGMBAgomAb Therapeutics NV | SPONSORED ADS | 600,000 | $7.79M | 0.1% | 00.0% | Unchanged | History |
| CGEMCullinan Therapeutics, Inc. | COM | 426,478 | $7.77M | 0.1% | +426,478 | New | History |
| QUREuniQure N.V. | SHS | 168,000 | $7.74M | 0.1% | +168,000 | New | History |
| MOBIMobia Medical, Inc. | COMMON STOCK | 523,654 | $7.02M | 0.1% | +523,654 | New | History |
| ADGMAdagio Medical Holdings, Inc. | COM | 9,876,586 | $6.44M | 0.1% | +100.0% | Added | History |
| GHGuardant Health, Inc. | COM | 41,327 | $6.20M | 0.1% | −258,673−86.2% | Reduced | History |
| PHATPhathom Pharmaceuticals, Inc. | COM | 532,000 | $5.77M | 0.1% | −393,000−42.5% | Reduced | History |
| OTLKOutlook Therapeutics, Inc. | Stock | 3,139,216 | $4.99M | 0.1% | +3,139,216 | New | History |
| COGTCogent Biosciences, Inc. | COM | 121,082 | $4.69M | 0.1% | 00.0% | Unchanged | History |
| EDSAEdesa Biotech, Inc. | COM NEW | 563,239 | $4.58M | 0.1% | 00.0% | Unchanged | History |
| AVTXAvalo Therapeutics, Inc. | COM NEW | 219,813 | $4.06M | 0.1% | +80,146+57.4% | Added | History |
| TWSTTwist Bioscience Corp | COM | 36,812 | $3.79M | 0.1% | −113,188−75.5% | Reduced | History |
| CBIOCrescent Biopharma, Inc. | COM | 206,942 | $3.72M | 0.1% | 00.0% | Unchanged | History |
| XERSXeris Biopharma Holdings, Inc. | COM | 467,013 | $3.70M | 0.1% | +467,013 | New | History |
| OMOutset Medical, Inc. | COM NEW | 833,333 | $3.60M | 0.1% | 00.0% | Unchanged | History |
| BDSXBiodesix Inc | COM | 108,694 | $2.45M | <0.1% | +108,694 | New | History |
| RVMDWRevolution Medicines, Inc. | *W EXP 12/17/202 | 250,000 | $2.34M | <0.1% | 00.0% | Unchanged | History |
| CNTBConnect Biopharma Holdings Ltd | SHS | 792,696 | $1.89M | <0.1% | 00.0% | Unchanged | History |
| KPRXKiora Pharmaceuticals Inc | COM | 438,471 | $1.15M | <0.1% | +438,471 | New | History |
| MDLNMedline Inc. | COM CL A | 28,000 | $1.10M | <0.1% | 00.0% | Unchanged | History |
| ADMAAdma Biologics, Inc. | COM | 113,765 | $952.2K | <0.1% | −353,468−75.7% | Reduced | History |
| CPIXCumberland Pharmaceuticals Inc | COM | 96,982 | $628.4K | <0.1% | −99,996−50.8% | Reduced | History |
| XGNExagen Inc. | COM | 114,893 | $534.3K | <0.1% | 00.0% | Unchanged | History |
Options (6)
Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.
| Security | Class | Puts | Calls |
|---|---|---|---|
| MRNAModerna, Inc. | Stock | $70.0M | – |
| State Street SPDR S&P Biotech ETF78464A870 | ETF | $47.5M | – |
| CAPRCapricor Therapeutics, Inc. | COM NEW | $12.0M | $24.1M |
| EYPTEyePoint, Inc. | COM NEW | $28.6M | – |
| SLSSELLAS Life Sciences Group, Inc. | COM NEW | $22.1M | – |
| NAMSNewAmsterdam Pharma Co N.V. | ORDINARY SHARES | $16.9M | – |
Sold out since Q1 2026 (11)
Positions held at the end of Q1 2026 that are gone from this filing.
| Security | Class | Shares in Q1 2026 | Value in Q1 2026 | % of portfolio in Q1 2026 | History |
|---|---|---|---|---|---|
| CNTACentessa Pharmaceuticals plc | SPONSORED ADS | 5,258,903 | $208.9M | 4.1% | History |
| DAWNDay One Biopharmaceuticals, Inc. | Stock | 1,755,799 | $37.6M | 0.7% | History |
| DRUGBright Minds Biosciences Inc. | COM NEW | 377,544 | $27.5M | 0.5% | History |
| BLTEBelite Bio, Inc | SPONSORED ADS | 151,979 | $24.2M | 0.5% | History |
| EVMNEvommune, Inc. | COM SHS | 448,350 | $10.3M | 0.2% | History |
| NMRANeumora Therapeutics, Inc. | COM | 5,104,097 | $9.95M | 0.2% | History |
| NBIXNeurocrine Biosciences Inc | Stock | 65,050 | $8.57M | 0.2% | History |
| IRDOpus Genetics, Inc. | COM | 1,835,842 | $8.35M | 0.2% | History |
| IKTInhibikase Therapeutics, Inc. | COM NEW | 2,315,000 | $3.89M | 0.1% | History |
| APLSApellis Pharmaceuticals, Inc. | COM | 80,956 | $3.26M | 0.1% | History |
| PTNPalatin Technologies Inc | COM NEW | 61,945 | $1.08M | <0.1% | History |