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Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q2 2026

Holdings as of Jun 30, 2026, filed Aug 14, 2026. Long positions only; changes compare share counts with Q1 2026.

Institution overview
Positions
102
+10 vs. Q1 2026
Portfolio value
$6.44B
+$1.38B (+27.2%) vs. Q1 2026
Filed
Aug 14, 2026
SEC
Holdings of Perceptive Advisors LLC in Q2 2026
SecurityClassSharesValue% of portfolioShare changeActionHistory
Surrozen, Inc.86889P117*W EXP 08/01/203166,666$2.75K<0.1%00.0%Unchanged–
ENSCEnsysce Biosciences, Inc.COM NEW86,666$25.1K<0.1%00.0%UnchangedHistory
XGNExagen Inc.COM114,893$534.3K<0.1%00.0%UnchangedHistory
CPIXCumberland Pharmaceuticals IncCOM96,982$628.4K<0.1%−99,996−50.8%ReducedHistory
ADMAAdma Biologics, Inc.COM113,765$952.2K<0.1%−353,468−75.7%ReducedHistory
MDLNMedline Inc.COM CL A28,000$1.10M<0.1%00.0%UnchangedHistory
KPRXKiora Pharmaceuticals IncCOM438,471$1.15M<0.1%+438,471NewHistory
CNTBConnect Biopharma Holdings LtdSHS792,696$1.89M<0.1%00.0%UnchangedHistory
RVMDWRevolution Medicines, Inc.*W EXP 12/17/202250,000$2.34M<0.1%00.0%UnchangedHistory
BDSXBiodesix IncCOM108,694$2.45M<0.1%+108,694NewHistory
OMOutset Medical, Inc.COM NEW833,333$3.60M0.1%00.0%UnchangedHistory
XERSXeris Biopharma Holdings, Inc.COM467,013$3.70M0.1%+467,013NewHistory
CBIOCrescent Biopharma, Inc.COM206,942$3.72M0.1%00.0%UnchangedHistory
TWSTTwist Bioscience CorpCOM36,812$3.79M0.1%−113,188−75.5%ReducedHistory
AVTXAvalo Therapeutics, Inc.COM NEW219,813$4.06M0.1%+80,146+57.4%AddedHistory
EDSAEdesa Biotech, Inc.COM NEW563,239$4.58M0.1%00.0%UnchangedHistory
COGTCogent Biosciences, Inc.COM121,082$4.69M0.1%00.0%UnchangedHistory
OTLKOutlook Therapeutics, Inc.Stock3,139,216$4.99M0.1%+3,139,216NewHistory
PHATPhathom Pharmaceuticals, Inc.COM532,000$5.77M0.1%−393,000−42.5%ReducedHistory
GHGuardant Health, Inc.COM41,327$6.20M0.1%−258,673−86.2%ReducedHistory
ADGMAdagio Medical Holdings, Inc.COM9,876,586$6.44M0.1%+100.0%AddedHistory
MOBIMobia Medical, Inc.COMMON STOCK523,654$7.02M0.1%+523,654NewHistory
QUREuniQure N.V.SHS168,000$7.74M0.1%+168,000NewHistory
CGEMCullinan Therapeutics, Inc.COM426,478$7.77M0.1%+426,478NewHistory
AGMBAgomAb Therapeutics NVSPONSORED ADS600,000$7.79M0.1%00.0%UnchangedHistory
RACCResearch Alliance Corp IIIORD SHS CL A750,000$8.03M0.1%+750,000NewHistory
ENGNenGene Therapeutics Inc.COM4,822,169$8.34M0.1%−1,005,337−17.3%ReducedHistory
NTRANatera, Inc.COM34,689$9.42M0.1%+34,689NewHistory
ABVXAbivax S.A.SPONSORED ADS74,000$9.86M0.2%−254,884−77.5%ReducedHistory
BLLNBillionToOne, Inc.CL A86,812$10.4M0.2%−5,000−5.4%ReducedHistory
BSXBoston Scientific CorpStock250,000$10.7M0.2%+250,000NewHistory
VRDNViridian Therapeutics, Inc.COM581,980$10.7M0.2%−588,849−50.3%ReducedHistory
SPTXSeaport Therapeutics, Inc.COMMON STOCK500,000$10.9M0.2%+500,000NewHistory
OCSOculis Holding AGORDINARY SHARES808,827$11.2M0.2%+315,000+63.8%AddedHistory
OSCROscar Health, Inc.CL A400,000$11.4M0.2%+400,000NewHistory
AXGNAxogen, Inc.COM247,312$11.4M0.2%−450,000−64.5%ReducedHistory
BBNXBeta Bionics, Inc.COM832,944$13.1M0.2%−10,000−1.2%ReducedHistory
SRZNSurrozen, Inc.COM NEW503,985$13.1M0.2%+274,592+119.7%AddedHistory
MIRMMirum Pharmaceuticals, Inc.COM115,391$13.5M0.2%+115,391NewHistory
Celcuity Inc.15102KAA8NOTE 2.750% 8/0–$14.6M0.2%–––
IVVDInvivyd, Inc.COM18,490,636$16.1M0.3%−2,368,667−11.4%ReducedHistory
EOLSEvolus, Inc.COM2,459,285$17.1M0.3%+1,172,423+91.1%AddedHistory
LONALeonaBio, Inc.COM1,859,322$17.1M0.3%00.0%UnchangedHistory
OMDAOmada Health, Inc.COM786,330$17.3M0.3%00.0%UnchangedHistory
PALIPalisade Bio, Inc.COM8,425,065$17.6M0.3%−503,084−5.6%ReducedHistory
NVCTNuvectis Pharma, Inc.COM1,000,000$18.4M0.3%+1,000,000NewHistory
CTNMContineum Therapeutics, Inc.CL A1,255,592$20.6M0.3%00.0%UnchangedHistory
ANLAdlai Nortye Group Ltd.ADS1,793,190$20.6M0.3%+1,793,190NewHistory
ISRGIntuitive Surgical IncCOM NEW51,884$20.6M0.3%−33,535−39.3%ReducedHistory
OBIOOrchestra BioMed Holdings, Inc.COM5,037,906$21.7M0.3%00.0%UnchangedHistory
NAUTNautilus Biotechnology, Inc.COM11,634,211$21.8M0.3%−960,000−7.6%ReducedHistory
TENXTenax Therapeutics, Inc.COM NEW1,700,000$24.7M0.4%+252,218+17.4%AddedHistory
DHRDanaher CorpStock130,000$24.8M0.4%+130,000NewHistory
SABSSAB Biotherapeutics, Inc.COM NEW6,627,501$25.8M0.4%+195,758+3.0%AddedHistory
ADPTAdaptive Biotechnologies CorpCOM1,217,325$26.1M0.4%+1,064,825+698.2%AddedHistory
IRTCiRhythm Holdings, Inc.COM223,766$26.6M0.4%+118,740+113.1%AddedHistory
DBVTDBV Technologies S.A.SPONSORED ADS1,653,350$27.1M0.4%+688,959+71.4%AddedHistory
AXSMAxsome Therapeutics, Inc.COM118,450$29.0M0.5%−31,500−21.0%ReducedHistory
CRLCharles River Laboratories International, Inc.COM140,000$31.8M0.5%+140,000NewHistory
DMRADamora Therapeutics, Inc.COM NEW1,223,000$31.8M0.5%00.0%UnchangedHistory
RAPPRapport Therapeutics, Inc.COM773,342$32.2M0.5%+99,419+14.8%AddedHistory
AVRAnteris Technologies Global Corp.COM3,425,476$33.7M0.5%00.0%UnchangedHistory
RGENRepligen CorpCOM248,212$33.9M0.5%−32,329−11.5%ReducedHistory
CORTCorcept Therapeutics IncCOM398,385$34.6M0.5%+348,385+696.8%AddedHistory
XFORX4 Pharmaceuticals, IncCOM NEW7,933,491$37.0M0.6%+1,195,843+17.7%AddedHistory
AORTArtivion, Inc.COM1,737,290$39.0M0.6%+100,000+6.1%AddedHistory
CTMXCytomX Therapeutics, Inc.COM10,439,185$39.1M0.6%+340,361+3.4%AddedHistory
SIONSionna Therapeutics, Inc.COM905,000$39.8M0.6%+246,561+37.4%AddedHistory
CRVSCorvus Pharmaceuticals, Inc.COM2,667,441$39.9M0.6%+375,000+16.4%AddedHistory
JAZZJazz Pharmaceuticals plcSHS USD170,000$41.0M0.6%00.0%UnchangedHistory
ANROAlto Neuroscience, Inc.COM SHS1,609,893$42.5M0.7%−400,000−19.9%ReducedHistory
STROSutro Biopharma, Inc.COM SHS1,304,846$43.3M0.7%+589,539+82.4%AddedHistory
IONSIonis Pharmaceuticals IncCOM566,000$44.9M0.7%+62,000+12.3%AddedHistory
UNHUnitedHealth Group IncStock116,806$48.5M0.8%+116,806NewHistory
IMVTImmunovant, Inc.COM1,357,383$52.3M0.8%−240,000−15.0%ReducedHistory
BIIBBiogen Inc.COM276,173$59.7M0.9%+276,173NewHistory
DYNDyne Therapeutics, Inc.COM2,689,235$59.7M0.9%−1,979,604−42.4%ReducedHistory
AVLNAvalyn Pharma Inc.COM SHS2,675,296$88.1M1.4%+2,675,296NewHistory
RVMDRevolution Medicines, Inc.COM527,600$98.8M1.5%+269,000+104.0%AddedHistory
BCRXBiocryst Pharmaceuticals IncCOM10,308,888$103.1M1.6%+2,874,855+38.7%AddedHistory
NRIXNurix Therapeutics, Inc.COM4,320,422$104.8M1.6%+609,545+16.4%AddedHistory
IMTXImmatics N.V.SHS10,383,456$105.2M1.6%00.0%UnchangedHistory
TNGXTango Therapeutics, Inc.COM3,377,000$105.6M1.6%+2,568,847+317.9%AddedHistory
ZYMEZymeworks Inc.COM4,182,953$109.3M1.7%+672,875+19.2%AddedHistory
SLDBSolid Biosciences Inc.COM NEW11,906,646$118.9M1.8%00.0%UnchangedHistory
PTGXProtagonist Therapeutics, IncCOM981,879$120.4M1.9%−249,000−20.2%ReducedHistory
INBXInhibrx Biosciences, Inc.COM1,297,763$123.0M1.9%−144,944−10.0%ReducedHistory
ORKAOruka Therapeutics, Inc.COM1,345,063$128.0M2.0%−50,438−3.6%ReducedHistory
MGTXMeiraGTx Holdings plcCOM10,786,658$145.7M2.3%+460,555+4.5%AddedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM8,334,882$149.7M2.3%+50,000+0.6%AddedHistory
APGEApogee Therapeutics, Inc.COM1,308,113$173.6M2.7%−232,271−15.1%ReducedHistory
EWTXEdgewise Therapeutics, Inc.COM4,373,974$177.7M2.8%−50,000−1.1%ReducedHistory
NUVLNuvalent, Inc.COM1,580,505$195.2M3.0%00.0%UnchangedHistory
KARDKardigan, Inc.COM8,200,662$195.6M3.0%+8,200,662NewHistory
TVTXTravere Therapeutics, Inc.COM3,752,574$213.2M3.3%−389,977−9.4%ReducedHistory
RLAYRelay Therapeutics, Inc.COM14,106,187$263.9M4.1%+4,355,046+44.7%AddedHistory
ROIVRoivant Sciences Ltd.SHS8,085,461$286.1M4.4%−200,000−2.4%ReducedHistory
RYTMRhythm Pharmaceuticals, Inc.COM2,586,295$287.2M4.5%+212,500+9.0%AddedHistory
ASNDAscendis Pharma A/SORD SHS1,163,721$310.4M4.8%−367,700−24.0%ReducedHistory
CELCCelcuity Inc.COM3,197,200$334.5M5.2%+70,000+2.2%AddedHistory

Options (6)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q2 2026
SecurityClassPutsCalls
MRNAModerna, Inc.Stock$70.0M–
State Street SPDR S&P Biotech ETF78464A870ETF$47.5M–
CAPRCapricor Therapeutics, Inc.COM NEW$12.0M$24.1M
EYPTEyePoint, Inc.COM NEW$28.6M–
SLSSELLAS Life Sciences Group, Inc.COM NEW$22.1M–
NAMSNewAmsterdam Pharma Co N.V.ORDINARY SHARES$16.9M–

Sold out since Q1 2026 (11)

Positions held at the end of Q1 2026 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q1 2026
SecurityClassShares in Q1 2026Value in Q1 2026% of portfolio in Q1 2026History
CNTACentessa Pharmaceuticals plcSPONSORED ADS5,258,903$208.9M4.1%History
DAWNDay One Biopharmaceuticals, Inc.Stock1,755,799$37.6M0.7%History
DRUGBright Minds Biosciences Inc.COM NEW377,544$27.5M0.5%History
BLTEBelite Bio, IncSPONSORED ADS151,979$24.2M0.5%History
EVMNEvommune, Inc.COM SHS448,350$10.3M0.2%History
NMRANeumora Therapeutics, Inc.COM5,104,097$9.95M0.2%History
NBIXNeurocrine Biosciences IncStock65,050$8.57M0.2%History
IRDOpus Genetics, Inc.COM1,835,842$8.35M0.2%History
IKTInhibikase Therapeutics, Inc.COM NEW2,315,000$3.89M0.1%History
APLSApellis Pharmaceuticals, Inc.COM80,956$3.26M0.1%History
PTNPalatin Technologies IncCOM NEW61,945$1.08M<0.1%History