Perceptive Advisors LLC
- SEC CIK
- 0001224962
- Latest filing
- Aug 14, 2026
Holdings in Q1 2025
Holdings as of Mar 31, 2025, filed Aug 6, 2025. Long positions only; changes compare share counts with Q4 2024.
- Positions
- 86
- −11 vs. Q4 2024
- Portfolio value
- $2.82B
- −$769.7M (−21.4%) vs. Q4 2024
| Security | Class | Shares | Value | % of portfolio | Share change | Action | History |
|---|---|---|---|---|---|---|---|
| Surrozen, Inc.86889P117 | *W EXP 08/01/203 | 166,666 | $5.00K | <0.1% | 00.0% | Unchanged | – |
| RVMDWRevolution Medicines, Inc. | *W EXP 12/17/202 | 250,000 | $9.50K | <0.1% | 00.0% | Unchanged | History |
| APYXApyx Medical Corp | COM | 150,000 | $205.5K | <0.1% | 00.0% | Unchanged | History |
| ENSCEnsysce Biosciences, Inc. | COM NEW | 86,666 | $221.9K | <0.1% | 00.0% | Unchanged | History |
| NBTXNanobiotix S.A. | SPONSORED ADS | 105,053 | $376.1K | <0.1% | −161,040−60.5% | Reduced | History |
| APLTApplied Therapeutics, Inc. | COM | 860,000 | $420.5K | <0.1% | 00.0% | Unchanged | History |
| LXEOLexeo Therapeutics, Inc. | COM | 139,835 | $485.2K | <0.1% | 00.0% | Unchanged | History |
| CGEMCullinan Therapeutics, Inc. | COM | 80,100 | $606.4K | <0.1% | +80,100 | New | History |
| RCKTRocket Pharmaceuticals, Inc. | COM | 140,726 | $938.6K | <0.1% | −237,858−62.8% | Reduced | History |
| TRAWTraws Pharma, Inc. | COM NEW | 421,781 | $970.1K | <0.1% | +257,624+156.9% | Added | History |
| SCPHscPharmaceuticals Inc. | COM | 500,000 | $1.31M | <0.1% | 00.0% | Unchanged | History |
| BDSXBiodesix Inc | COM | 2,173,880 | $1.36M | <0.1% | 00.0% | Unchanged | History |
| LONALeonaBio, Inc. | COM | 5,402,964 | $1.54M | 0.1% | 00.0% | Unchanged | History |
| KALAKALA BIO, Inc. | COMM STK | 277,610 | $1.59M | 0.1% | +277,610 | New | History |
| LYRALyra Therapeutics, Inc. | COM | 12,757,562 | $1.61M | 0.1% | 00.0% | Unchanged | History |
| MREOMereo BioPharma Group plc | SPON ADS | 876,961 | $1.97M | 0.1% | −208,551−19.2% | Reduced | History |
| NRIXNurix Therapeutics, Inc. | COM | 297,553 | $3.53M | 0.1% | −33,061−10.0% | Reduced | History |
| AVTXAvalo Therapeutics, Inc. | COM NEW | 520,000 | $4.17M | 0.1% | +520,000 | New | History |
| IRDOpus Genetics, Inc. | COM | 4,325,000 | $4.25M | 0.2% | +4,325,000 | New | History |
| OKUROnKure Therapeutics, Inc. | COM CL A | 1,004,439 | $4.32M | 0.2% | 00.0% | Unchanged | History |
| BBOTBridgeBio Oncology Therapeutics, Inc. | CL A ORD SHS | 398,000 | $4.50M | 0.2% | −102,000−20.4% | Reduced | History |
| KMTSKestra Medical Technologies, Ltd. | SHS | 200,000 | $4.98M | 0.2% | +200,000 | New | History |
| RAPTRAPT Therapeutics, Inc. | COM | 4,418,947 | $5.39M | 0.2% | −1,461,053−24.8% | Reduced | History |
| DCTHDelcath Systems, Inc. | COM NEW | 462,422 | $5.89M | 0.2% | +412,422+824.8% | Added | History |
| OCULOcular Therapeutix, Inc | COM | 915,775 | $6.71M | 0.2% | −162,720−15.1% | Reduced | History |
| ADPTAdaptive Biotechnologies Corp | COM | 930,972 | $6.92M | 0.2% | +930,972 | New | History |
| IRONDisc Medicine, Inc. | COM | 150,000 | $7.45M | 0.3% | +150,000 | New | History |
| AVRAnteris Technologies Global Corp. | COM | 2,140,000 | $7.79M | 0.3% | 00.0% | Unchanged | History |
| ADGMAdagio Medical Holdings, Inc. | COM | 9,812,419 | $7.90M | 0.3% | 00.0% | Unchanged | History |
| EYPTEyePoint, Inc. | COM NEW | 1,537,274 | $8.33M | 0.3% | 00.0% | Unchanged | History |
| VRDNViridian Therapeutics, Inc. | COM | 659,662 | $8.89M | 0.3% | −826,846−55.6% | Reduced | History |
| OMOutset Medical, Inc. | COM NEW | 833,333 | $9.22M | 0.3% | +833,333 | New | History |
| CRGXCARGO Therapeutics, Inc. | COM | 2,431,085 | $9.89M | 0.4% | −1,251,919−34.0% | Reduced | History |
| CTNMContineum Therapeutics, Inc. | CL A | 1,441,249 | $10.1M | 0.4% | 00.0% | Unchanged | History |
| AQSTAquestive Therapeutics, Inc. | COM | 3,727,208 | $10.8M | 0.4% | +3,727,208 | New | History |
| NAUTNautilus Biotechnology, Inc. | COM | 12,594,211 | $10.8M | 0.4% | 00.0% | Unchanged | History |
| ACRVAcrivon Therapeutics, Inc. | COMMON STOCK | 5,360,858 | $10.9M | 0.4% | 00.0% | Unchanged | History |
| XENEXenon Pharmaceuticals Inc. | COM | 325,324 | $10.9M | 0.4% | 00.0% | Unchanged | History |
| NBIXNeurocrine Biosciences Inc | Stock | 100,050 | $11.1M | 0.4% | 00.0% | Unchanged | History |
| DXCMDexcom Inc | COM | 178,000 | $12.2M | 0.4% | +178,000 | New | History |
| VKTXViking Therapeutics, Inc. | COM | 509,005 | $12.3M | 0.4% | −486,889−48.9% | Reduced | History |
| IKTInhibikase Therapeutics, Inc. | COM NEW | 5,925,000 | $13.0M | 0.5% | 00.0% | Unchanged | History |
| SIONSionna Therapeutics, Inc. | COM | 1,251,101 | $13.1M | 0.5% | +1,251,101 | New | History |
| BSXBoston Scientific Corp | Stock | 130,000 | $13.1M | 0.5% | +130,000 | New | History |
| INBXInhibrx Biosciences, Inc. | COM | 1,064,026 | $14.9M | 0.5% | 00.0% | Unchanged | History |
| MDGLMadrigal Pharmaceuticals, Inc. | COM | 46,500 | $15.4M | 0.5% | +46,500 | New | History |
| DRUGBright Minds Biosciences Inc. | COM NEW | 444,649 | $16.0M | 0.6% | +41,000+10.2% | Added | History |
| RGENRepligen Corp | COM | 129,801 | $16.5M | 0.6% | +129,801 | New | History |
| PODDInsulet Corp | Stock | 71,597 | $18.8M | 0.7% | −160,672−69.2% | Reduced | History |
| BBNXBeta Bionics, Inc. | COM | 1,593,608 | $19.5M | 0.7% | +1,593,608 | New | History |
| OBIOOrchestra BioMed Holdings, Inc. | COM | 4,592,556 | $19.7M | 0.7% | 00.0% | Unchanged | History |
| ISRGIntuitive Surgical Inc | COM NEW | 40,619 | $20.1M | 0.7% | −22,500−35.6% | Reduced | History |
| ZYMEZymeworks Inc. | COM | 1,864,672 | $22.2M | 0.8% | −265,348−12.5% | Reduced | History |
| CELCCelcuity Inc. | COM | 2,362,279 | $23.9M | 0.8% | 00.0% | Unchanged | History |
| DYNDyne Therapeutics, Inc. | COM | 2,313,403 | $24.2M | 0.9% | +1,770,126+325.8% | Added | History |
| JANXJanux Therapeutics, Inc. | COM | 970,412 | $26.2M | 0.9% | +152,517+18.6% | Added | History |
| PCVXVaxcyte, Inc. | COM | 706,567 | $26.7M | 0.9% | −1,011,850−58.9% | Reduced | History |
| ADMAAdma Biologics, Inc. | COM | 1,373,233 | $27.2M | 1.0% | +482,953+54.2% | Added | History |
| AMLXAmylyx Pharmaceuticals, Inc. | COM | 7,874,348 | $27.9M | 1.0% | +1,100,000+16.2% | Added | History |
| MRUSMerus N.V. | COM | 690,485 | $29.1M | 1.0% | +390,485+130.2% | Added | History |
| AKROAkero Therapeutics, Inc. | COM | 792,960 | $32.1M | 1.1% | −392,632−33.1% | Reduced | History |
| ATXSAstria Therapeutics, Inc. | COM | 6,485,420 | $34.6M | 1.2% | 00.0% | Unchanged | History |
| ARGXArgenx SE | SPONSORED ADR | 59,510 | $35.2M | 1.2% | −7,961−11.8% | Reduced | History |
| PRAXPraxis Precision Medicines, Inc. | COM NEW | 980,894 | $37.1M | 1.3% | −348,841−26.2% | Reduced | History |
| SYRESpyre Therapeutics, Inc. | COM NEW | 2,313,272 | $37.3M | 1.3% | −261,451−10.2% | Reduced | History |
| INSMINSMED Inc | COM PAR $.01 | 509,300 | $38.9M | 1.4% | +365,300+253.7% | Added | History |
| AXSMAxsome Therapeutics, Inc. | COM | 355,107 | $41.4M | 1.5% | −308,967−46.5% | Reduced | History |
| APGEApogee Therapeutics, Inc. | COM | 1,122,767 | $41.9M | 1.5% | +75,535+7.2% | Added | History |
| IMTXImmatics N.V. | SHS | 9,383,456 | $42.3M | 1.5% | 00.0% | Unchanged | History |
| IOVAIovance Biotherapeutics, Inc. | COM | 12,711,788 | $42.3M | 1.5% | −9,400,478−42.5% | Reduced | History |
| CNTACentessa Pharmaceuticals plc | SPONSORED ADS | 3,040,395 | $43.7M | 1.6% | −3,308,825−52.1% | Reduced | History |
| SLDBSolid Biosciences Inc. | COM NEW | 11,906,646 | $44.1M | 1.6% | +5,000,000+72.4% | Added | History |
| IMVTImmunovant, Inc. | COM | 2,844,072 | $48.6M | 1.7% | +704,873+33.0% | Added | History |
| EOLSEvolus, Inc. | COM | 4,129,142 | $49.7M | 1.8% | −1,016,704−19.8% | Reduced | History |
| PTGXProtagonist Therapeutics, Inc | COM | 1,091,271 | $52.8M | 1.9% | −180,391−14.2% | Reduced | History |
| ALDXAldeyra Therapeutics, Inc. | COM | 9,275,851 | $53.3M | 1.9% | 00.0% | Unchanged | History |
| AORTArtivion, Inc. | COM | 2,793,703 | $68.7M | 2.4% | 00.0% | Unchanged | History |
| MGTXMeiraGTx Holdings plc | COM | 12,581,103 | $85.3M | 3.0% | 00.0% | Unchanged | History |
| ITCIIntra-Cellular Therapies, Inc. | COM | 786,358 | $103.7M | 3.7% | −501,970−39.0% | Reduced | History |
| SLNOSoleno Therapeutics Inc | COM | 1,506,602 | $107.6M | 3.8% | +5,562+0.4% | Added | History |
| NUVLNuvalent, Inc. | COM | 1,633,968 | $115.9M | 4.1% | −986,009−37.6% | Reduced | History |
| RYTMRhythm Pharmaceuticals, Inc. | COM | 2,548,445 | $135.0M | 4.8% | −1,132,028−30.8% | Reduced | History |
| EWTXEdgewise Therapeutics, Inc. | COM | 6,547,328 | $144.0M | 5.1% | +3,861,791+143.8% | Added | History |
| FOLDAmicus Therapeutics, Inc. | COM | 21,464,527 | $175.2M | 6.2% | −2,781,425−11.5% | Reduced | History |
| ACLXArcellx, Inc. | COMMON STOCK | 2,926,478 | $192.0M | 6.8% | −552,410−15.9% | Reduced | History |
| VRNAVerona Pharma plc | SPONSORED ADS | 6,563,340 | $416.7M | 14.8% | +171,234+2.7% | Added | History |
Options (1)
Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.
| Security | Class | Puts | Calls |
|---|---|---|---|
| EWTXEdgewise Therapeutics, Inc. | COM | – | $11.0M |
Sold out since Q4 2024 (26)
Positions held at the end of Q4 2024 that are gone from this filing.
| Security | Class | Shares in Q4 2024 | Value in Q4 2024 | % of portfolio in Q4 2024 | History |
|---|---|---|---|---|---|
| PRCTPROCEPT BioRobotics Corp | COM | 290,659 | $23.4M | 0.7% | History |
| NTRANatera, Inc. | COM | 125,000 | $19.8M | 0.6% | History |
| PENPenumbra Inc | COM | 73,338 | $17.4M | 0.5% | History |
| SEPNSepterna, Inc. | COM | 750,000 | $17.2M | 0.5% | History |
| ORKAOruka Therapeutics, Inc. | COM | 845,567 | $16.4M | 0.5% | History |
| ARVNArvinas, Inc. | COM | 740,749 | $14.2M | 0.4% | History |
| CGONCG Oncology, Inc. | COM | 419,450 | $12.0M | 0.3% | History |
| EWEdwards Lifesciences Corp | Stock | 145,000 | $10.7M | 0.3% | History |
| TARSTarsus Pharmaceuticals, Inc. | COM | 186,662 | $10.3M | 0.3% | History |
| CRNXCrinetics Pharmaceuticals, Inc. | COM | 184,525 | $9.43M | 0.3% | History |
| NARIInari Medical, Inc. | Stock | 178,797 | $9.13M | 0.3% | History |
| ZBIOZenas BioPharma, Inc. | COM | 744,035 | $6.09M | 0.2% | History |
| IRTCiRhythm Holdings, Inc. | COM | 65,153 | $5.87M | 0.2% | History |
| RAPPRapport Therapeutics, Inc. | COM | 311,551 | $5.53M | 0.2% | History |
| CBLLCeribell, Inc. | COM | 180,546 | $4.67M | 0.1% | History |
| VERUVeru Inc. | COM | 6,483,157 | $4.22M | 0.1% | History |
| CATXPerspective Therapeutics, Inc. | COM NEW | 1,190,263 | $3.80M | 0.1% | History |
| LCTXLineage Cell Therapeutics, Inc. | COM | 7,236,843 | $3.64M | 0.1% | History |
| PEPGPepGen Inc. | COM | 829,536 | $3.14M | 0.1% | History |
| IBRXImmunityBio, Inc. | COM | 1,221,734 | $3.13M | 0.1% | History |
| BCYCBicycle Therapeutics PLC | SPONSORED ADS | 197,108 | $2.76M | 0.1% | History |
| VRCAVerrica Pharmaceuticals Inc. | COM | 3,249,669 | $2.27M | 0.1% | History |
| FBRXForte Biosciences, Inc. | COM NEW | 95,742 | $2.17M | 0.1% | History |
| TRIBTrinity Biotech PLC | SPONS ADR NEW | 1,790,000 | $1.58M | <0.1% | History |
| FULCFulcrum Therapeutics, Inc. | COM | 238,000 | $1.12M | <0.1% | History |
| PYXSPyxis Oncology, Inc. | COMMON STOCK | 188,462 | $294.0K | <0.1% | History |