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Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q3 2024

Holdings as of Sep 30, 2024, filed Nov 14, 2024. Long positions only; changes compare share counts with Q2 2024.

Institution overview
Positions
102
−5 vs. Q2 2024
Portfolio value
$4.66B
+$517.8M (+12.5%) vs. Q2 2024
Filed
Nov 14, 2024
SEC
Holdings of Perceptive Advisors LLC in Q3 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
ACLXArcellx, Inc.COMMON STOCK3,888,669$324.7M7.0%−1,0700.0%ReducedHistory
NUVLNuvalent, Inc.COM2,979,235$304.8M6.5%+430,158+16.9%AddedHistory
FOLDAmicus Therapeutics, Inc.COM28,057,456$299.7M6.4%00.0%UnchangedHistory
IOVAIovance Biotherapeutics, Inc.COM26,617,709$249.9M5.4%+684,567+2.6%AddedHistory
PCVXVaxcyte, Inc.COM2,027,608$231.7M5.0%+165,000+8.9%AddedHistory
RYTMRhythm Pharmaceuticals, Inc.COM3,560,214$186.5M4.0%+113,635+3.3%AddedHistory
VRNAVerona Pharma plcSPONSORED ADS6,315,933$181.7M3.9%+3,882,208+159.5%AddedHistory
SLNOSoleno Therapeutics IncCOM3,204,976$161.8M3.5%00.0%UnchangedHistory
ITCIIntra-Cellular Therapies, Inc.COM1,622,215$118.7M2.5%−94,192−5.5%ReducedHistory
APGEApogee Therapeutics, Inc.COM2,015,007$118.4M2.5%−90,629−4.3%ReducedHistory
VKTXViking Therapeutics, Inc.COM1,699,987$107.6M2.3%+978,610+135.7%AddedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS6,282,290$100.5M2.2%+2,348,983+59.7%AddedHistory
IMTXImmatics N.V.SHS8,086,159$92.3M2.0%00.0%UnchangedHistory
EOLSEvolus, Inc.COM5,356,622$86.8M1.9%−397,176−6.9%ReducedHistory
SYRESpyre Therapeutics, Inc.COM NEW2,872,547$84.5M1.8%−158,471−5.2%ReducedHistory
AORTArtivion, Inc.COM2,793,703$74.4M1.6%00.0%UnchangedHistory
BHVNBiohaven Ltd.COM1,485,232$74.2M1.6%00.0%UnchangedHistory
ATXSAstria Therapeutics, Inc.COM6,485,420$71.4M1.5%00.0%UnchangedHistory
AXSMAxsome Therapeutics, Inc.COM782,844$70.4M1.5%+323,733+70.5%AddedHistory
APLTApplied Therapeutics, Inc.COM8,005,000$68.0M1.5%00.0%UnchangedHistory
CRGXCARGO Therapeutics, Inc.COM3,683,004$68.0M1.5%00.0%UnchangedHistory
IMVTImmunovant, Inc.COM2,378,762$67.8M1.5%+454,976+23.7%AddedHistory
PRAXPraxis Precision Medicines, Inc.COM NEW1,164,035$67.0M1.4%+413,805+55.2%AddedHistory
ARGXArgenx SESPONSORED ADR118,839$64.4M1.4%+103,239+661.8%AddedHistory
VRDNViridian Therapeutics, Inc.COM2,812,665$64.0M1.4%+1,180,837+72.4%AddedHistory
EWTXEdgewise Therapeutics, Inc.COM2,330,294$62.2M1.3%+473,877+25.5%AddedHistory
PTGXProtagonist Therapeutics, IncCOM1,374,563$61.9M1.3%+105,828+8.3%AddedHistory
MGTXMeiraGTx Holdings plcCOM12,581,103$52.4M1.1%+1,250,000+11.0%AddedHistory
ALDXAldeyra Therapeutics, Inc.COM9,275,851$50.0M1.1%00.0%UnchangedHistory
AKROAkero Therapeutics, Inc.COM1,714,806$49.2M1.1%+214,909+14.3%AddedHistory
SLDBSolid Biosciences Inc.COM NEW6,906,646$48.1M1.0%00.0%UnchangedHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$42.6M0.9%00.0%UnchangedHistory
ACRVAcrivon Therapeutics, Inc.COMMON STOCK5,360,858$37.5M0.8%00.0%UnchangedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM724,698$37.0M0.8%−751,505−50.9%ReducedHistory
NAUTNautilus Biotechnology, Inc.COM12,594,211$35.9M0.8%00.0%UnchangedHistory
CELCCelcuity Inc.COM2,362,279$35.2M0.8%00.0%UnchangedHistory
PODDInsulet CorpStock142,269$33.1M0.7%+142,269NewHistory
ORKAOruka Therapeutics, Inc.COM1,235,187$30.3M0.6%+1,235,187NewHistory
CTNMContineum Therapeutics, Inc.CL A1,516,668$29.0M0.6%−50,000−3.2%ReducedHistory
OCULOcular Therapeutix, IncCOM3,324,468$28.9M0.6%00.0%UnchangedHistory
ISRGIntuitive Surgical IncCOM NEW58,119$28.6M0.6%−3,681−6.0%ReducedHistory
NTRANatera, Inc.COM220,000$27.9M0.6%−310,000−58.5%ReducedHistory
CGONCG Oncology, Inc.COM733,695$27.7M0.6%00.0%UnchangedHistory
ZYMEZymeworks Inc.COM2,180,020$27.4M0.6%+512,309+30.7%AddedHistory
DYNDyne Therapeutics, Inc.COM718,144$25.8M0.6%+718,144NewHistory
ADGMAdagio Medical Holdings, Inc.COM9,812,419$25.3M0.5%+9,812,419NewHistory
ARVNArvinas, Inc.COM1,027,749$25.3M0.5%00.0%UnchangedHistory
PRCTPROCEPT BioRobotics CorpCOM315,659$25.3M0.5%+105,000+49.8%AddedHistory
NBIXNeurocrine Biosciences IncStock212,228$24.5M0.5%−437,681−67.3%ReducedHistory
OBIOOrchestra BioMed Holdings, Inc.COM4,592,556$23.6M0.5%+2,046,675+80.4%AddedHistory
TILInstil Bio, Inc.COM NEW345,545$23.3M0.5%+345,545NewHistory
LIVNLivaNova PLCSHS429,000$22.5M0.5%−15,000−3.4%ReducedHistory
SWTXSpringWorks Therapeutics, Inc.COM692,263$22.2M0.5%−960,699−58.1%ReducedHistory
MDTMedtronic plcStock245,332$22.1M0.5%−245,333−50.0%ReducedHistory
ADMAAdma Biologics, Inc.COM1,060,200$21.2M0.5%−1,710,800−61.7%ReducedHistory
XENEXenon Pharmaceuticals Inc.COM524,930$20.7M0.4%−58,326−10.0%ReducedHistory
ZBIOZenas BioPharma, Inc.COM1,144,035$19.4M0.4%+1,144,035NewHistory
IRONDisc Medicine, Inc.COM387,017$19.0M0.4%−166,420−30.1%ReducedHistory
RCKTRocket Pharmaceuticals, Inc.COM931,851$17.2M0.4%−314,746−25.2%ReducedHistory
INBXInhibrx Biosciences, Inc.COM1,064,026$16.7M0.4%00.0%UnchangedHistory
RAPPRapport Therapeutics, Inc.COM748,183$15.3M0.3%00.0%UnchangedHistory
MRUSMerus N.V.COM300,000$15.0M0.3%00.0%UnchangedHistory
INSMINSMED IncCOM PAR $.01180,000$13.1M0.3%00.0%UnchangedHistory
ICLRIcon PLCCOM44,353$12.7M0.3%+13,103+41.9%AddedHistory
ARQTArcutis Biotherapeutics, Inc.COM1,358,500$12.6M0.3%−200,000−12.8%ReducedHistory
PEPGPepGen Inc.COM1,410,438$12.1M0.3%00.0%UnchangedHistory
TYRATyra Biosciences, Inc.COM511,226$12.0M0.3%−496,141−49.3%ReducedHistory
XNCRXencor IncCOM527,671$10.6M0.2%+527,671NewHistory
VRCAVerrica Pharmaceuticals Inc.COM7,099,182$10.3M0.2%00.0%UnchangedHistory
ROIVRoivant Sciences Ltd.SHS847,745$9.78M0.2%+847,745NewHistory
AVBPArriVent BioPharma, Inc.COM415,000$9.75M0.2%00.0%UnchangedHistory
EXASExact Sciences CorpCOM125,000$8.52M0.2%+125,000NewHistory
EYPTEyePoint, Inc.COM NEW1,037,274$8.29M0.2%+397,000+62.0%AddedHistory
ALLOAllogene Therapeutics, Inc.COM2,725,000$7.63M0.2%00.0%UnchangedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM2,125,649$6.89M0.1%+2,125,649NewHistory
BCYCBicycle Therapeutics PLCSPONSORED ADS255,994$5.79M0.1%−316,006−55.2%ReducedHistory
VERUVeru Inc.COM7,283,157$5.60M0.1%+219,880+3.1%AddedHistory
BBOTBridgeBio Oncology Therapeutics, Inc.CL A ORD SHS500,000$5.22M0.1%00.0%UnchangedHistory
BDSXBiodesix IncCOM2,173,880$3.87M0.1%00.0%UnchangedHistory
DTILPrecision Biosciences IncCOM NEW426,293$3.82M0.1%00.0%UnchangedHistory
MREOMereo BioPharma Group plcSPON ADS815,722$3.35M0.1%−437,528−34.9%ReducedHistory
LYRALyra Therapeutics, Inc.COM12,757,562$3.28M0.1%00.0%UnchangedHistory
NBTXNanobiotix S.A.SPONSORED ADS555,066$3.19M0.1%00.0%UnchangedHistory
ABSIAbsci CorpCOM700,000$2.67M0.1%00.0%UnchangedHistory
LONALeonaBio, Inc.COM5,402,964$2.41M0.1%00.0%UnchangedHistory
XFORX4 Pharmaceuticals, IncCOM3,545,454$2.37M0.1%00.0%UnchangedHistory
NVNOenVVeno Medical CorpCOMMON STOCK694,315$2.33M0.1%+71,000+11.4%AddedHistory
KYMRKymera Therapeutics, Inc.COM46,213$2.19M<0.1%+46,213NewHistory
TRIBTrinity Biotech PLCSPONS ADR NEW1,800,000$1.98M<0.1%00.0%UnchangedHistory
PYXSPyxis Oncology, Inc.COMMON STOCK508,462$1.87M<0.1%+508,462NewHistory
IRTCiRhythm Holdings, Inc.COM22,591$1.68M<0.1%−12,614−35.8%ReducedHistory
GPCRStructure Therapeutics Inc.SPONSORED ADS34,852$1.53M<0.1%00.0%UnchangedHistory
LXEOLexeo Therapeutics, Inc.COM139,835$1.26M<0.1%+139,835NewHistory
FATEFate Therapeutics IncCOM345,575$1.21M<0.1%00.0%UnchangedHistory
OMICSingular Genomics Systems, Inc.COM NEW50,896$797.5K<0.1%−20,000−28.2%ReducedHistory
KYTXKyverna Therapeutics, Inc.COM150,000$733.5K<0.1%00.0%UnchangedHistory
FBRXForte Biosciences, Inc.COM NEW95,742$535.2K<0.1%−34,872−26.7%ReducedConverted for a 1-for-25 splitHistory
SYRSSyros Pharmaceuticals, Inc.COM NEW116,754$251.0K<0.1%00.0%UnchangedHistory
CMAXCareMax, Inc.COMM STK100,000$170.0K<0.1%−22,643−18.5%ReducedHistory
RVMDWRevolution Medicines, Inc.*W EXP 12/17/202250,000$35.0K<0.1%00.0%UnchangedHistory

Options (5)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q3 2024
SecurityClassPutsCalls
State Street SPDR S&P Biotech ETF78464A870ETF$39.5M–
VRNAVerona Pharma plcSPONSORED ADS$7.19M$7.19M
FLNAFilana Therapeutics, Inc.COM$5.39M–
FULCFulcrum Therapeutics, Inc.COM–$5.36M
NVAXNovavax IncCOM NEW$1.26M–

Sold out since Q2 2024 (18)

Positions held at the end of Q2 2024 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q2 2024
SecurityClassShares in Q2 2024Value in Q2 2024% of portfolio in Q2 2024History
CERECerevel Therapeutics Holdings, Inc.COM10,794,876$441.4M10.7%History
MDGLMadrigal Pharmaceuticals, Inc.COM264,600$74.1M1.8%History
BBIOBridgeBio Pharma, Inc.COM1,215,346$30.8M0.7%History
CGEMCullinan Therapeutics, Inc.COM749,916$13.1M0.3%History
TEMTempus AI, Inc.CL A275,000$9.63M0.2%History
ENGNenGene Therapeutics Inc.COM800,000$7.54M0.2%History
SPRYARS Pharmaceuticals, Inc.COM867,319$7.38M0.2%History
KALVKalVista Pharmaceuticals, Inc.COM500,000$5.89M0.1%History
RXRXRecursion Pharmaceuticals, Inc.CL A769,230$5.77M0.1%History
CABACabaletta Bio, Inc.COM585,045$4.38M0.1%History
SKYESkye Bioscience, Inc.COM NEW500,000$4.00M0.1%History
FHTXFoghorn Therapeutics Inc.COM544,000$3.13M0.1%History
State Street SPDR S&P Biotech ETF78464A870ETF22,665$2.10M0.1%–
RVNCRevance Therapeutics, Inc.COM600,000$1.54M<0.1%History
EGRXEagle Pharmaceuticals, Inc.COM173,365$970.8K<0.1%History
VBIVVBI Vaccines Inc/BCCOM1,261,710$832.7K<0.1%History
TCMDTactile Systems Technology IncCOM62,639$747.9K<0.1%History
AXGNAxogen, Inc.COM30,421$220.2K<0.1%History