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Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q3 2024

Holdings as of Sep 30, 2024, filed Nov 14, 2024. Long positions only; changes compare share counts with Q2 2024.

Institution overview
Positions
102
−5 vs. Q2 2024
Portfolio value
$4.66B
+$517.8M (+12.5%) vs. Q2 2024
Filed
Nov 14, 2024
SEC
Holdings of Perceptive Advisors LLC in Q3 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
CareMax, Inc.14171W111*W EXP 06/08/20260,000$594<0.1%00.0%Unchanged–
Surrozen, Inc.86889P117*W EXP 08/01/203166,666$1.72K<0.1%00.0%Unchanged–
RVMDWRevolution Medicines, Inc.*W EXP 12/17/202250,000$35.0K<0.1%00.0%UnchangedHistory
CMAXCareMax, Inc.COMM STK100,000$170.0K<0.1%−22,643−18.5%ReducedHistory
SYRSSyros Pharmaceuticals, Inc.COM NEW116,754$251.0K<0.1%00.0%UnchangedHistory
FBRXForte Biosciences, Inc.COM NEW95,742$535.2K<0.1%−34,872−26.7%ReducedConverted for a 1-for-25 splitHistory
KYTXKyverna Therapeutics, Inc.COM150,000$733.5K<0.1%00.0%UnchangedHistory
OMICSingular Genomics Systems, Inc.COM NEW50,896$797.5K<0.1%−20,000−28.2%ReducedHistory
FATEFate Therapeutics IncCOM345,575$1.21M<0.1%00.0%UnchangedHistory
LXEOLexeo Therapeutics, Inc.COM139,835$1.26M<0.1%+139,835NewHistory
GPCRStructure Therapeutics Inc.SPONSORED ADS34,852$1.53M<0.1%00.0%UnchangedHistory
IRTCiRhythm Holdings, Inc.COM22,591$1.68M<0.1%−12,614−35.8%ReducedHistory
PYXSPyxis Oncology, Inc.COMMON STOCK508,462$1.87M<0.1%+508,462NewHistory
TRIBTrinity Biotech PLCSPONS ADR NEW1,800,000$1.98M<0.1%00.0%UnchangedHistory
KYMRKymera Therapeutics, Inc.COM46,213$2.19M<0.1%+46,213NewHistory
NVNOenVVeno Medical CorpCOMMON STOCK694,315$2.33M0.1%+71,000+11.4%AddedHistory
XFORX4 Pharmaceuticals, IncCOM3,545,454$2.37M0.1%00.0%UnchangedHistory
LONALeonaBio, Inc.COM5,402,964$2.41M0.1%00.0%UnchangedHistory
ABSIAbsci CorpCOM700,000$2.67M0.1%00.0%UnchangedHistory
NBTXNanobiotix S.A.SPONSORED ADS555,066$3.19M0.1%00.0%UnchangedHistory
LYRALyra Therapeutics, Inc.COM12,757,562$3.28M0.1%00.0%UnchangedHistory
MREOMereo BioPharma Group plcSPON ADS815,722$3.35M0.1%−437,528−34.9%ReducedHistory
DTILPrecision Biosciences IncCOM NEW426,293$3.82M0.1%00.0%UnchangedHistory
BDSXBiodesix IncCOM2,173,880$3.87M0.1%00.0%UnchangedHistory
BBOTBridgeBio Oncology Therapeutics, Inc.CL A ORD SHS500,000$5.22M0.1%00.0%UnchangedHistory
VERUVeru Inc.COM7,283,157$5.60M0.1%+219,880+3.1%AddedHistory
BCYCBicycle Therapeutics PLCSPONSORED ADS255,994$5.79M0.1%−316,006−55.2%ReducedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM2,125,649$6.89M0.1%+2,125,649NewHistory
ALLOAllogene Therapeutics, Inc.COM2,725,000$7.63M0.2%00.0%UnchangedHistory
EYPTEyePoint, Inc.COM NEW1,037,274$8.29M0.2%+397,000+62.0%AddedHistory
EXASExact Sciences CorpCOM125,000$8.52M0.2%+125,000NewHistory
AVBPArriVent BioPharma, Inc.COM415,000$9.75M0.2%00.0%UnchangedHistory
ROIVRoivant Sciences Ltd.SHS847,745$9.78M0.2%+847,745NewHistory
VRCAVerrica Pharmaceuticals Inc.COM7,099,182$10.3M0.2%00.0%UnchangedHistory
XNCRXencor IncCOM527,671$10.6M0.2%+527,671NewHistory
TYRATyra Biosciences, Inc.COM511,226$12.0M0.3%−496,141−49.3%ReducedHistory
PEPGPepGen Inc.COM1,410,438$12.1M0.3%00.0%UnchangedHistory
ARQTArcutis Biotherapeutics, Inc.COM1,358,500$12.6M0.3%−200,000−12.8%ReducedHistory
ICLRIcon PLCCOM44,353$12.7M0.3%+13,103+41.9%AddedHistory
INSMINSMED IncCOM PAR $.01180,000$13.1M0.3%00.0%UnchangedHistory
MRUSMerus N.V.COM300,000$15.0M0.3%00.0%UnchangedHistory
RAPPRapport Therapeutics, Inc.COM748,183$15.3M0.3%00.0%UnchangedHistory
INBXInhibrx Biosciences, Inc.COM1,064,026$16.7M0.4%00.0%UnchangedHistory
RCKTRocket Pharmaceuticals, Inc.COM931,851$17.2M0.4%−314,746−25.2%ReducedHistory
IRONDisc Medicine, Inc.COM387,017$19.0M0.4%−166,420−30.1%ReducedHistory
ZBIOZenas BioPharma, Inc.COM1,144,035$19.4M0.4%+1,144,035NewHistory
XENEXenon Pharmaceuticals Inc.COM524,930$20.7M0.4%−58,326−10.0%ReducedHistory
ADMAAdma Biologics, Inc.COM1,060,200$21.2M0.5%−1,710,800−61.7%ReducedHistory
MDTMedtronic plcStock245,332$22.1M0.5%−245,333−50.0%ReducedHistory
SWTXSpringWorks Therapeutics, Inc.COM692,263$22.2M0.5%−960,699−58.1%ReducedHistory
LIVNLivaNova PLCSHS429,000$22.5M0.5%−15,000−3.4%ReducedHistory
TILInstil Bio, Inc.COM NEW345,545$23.3M0.5%+345,545NewHistory
OBIOOrchestra BioMed Holdings, Inc.COM4,592,556$23.6M0.5%+2,046,675+80.4%AddedHistory
NBIXNeurocrine Biosciences IncStock212,228$24.5M0.5%−437,681−67.3%ReducedHistory
PRCTPROCEPT BioRobotics CorpCOM315,659$25.3M0.5%+105,000+49.8%AddedHistory
ARVNArvinas, Inc.COM1,027,749$25.3M0.5%00.0%UnchangedHistory
ADGMAdagio Medical Holdings, Inc.COM9,812,419$25.3M0.5%+9,812,419NewHistory
DYNDyne Therapeutics, Inc.COM718,144$25.8M0.6%+718,144NewHistory
ZYMEZymeworks Inc.COM2,180,020$27.4M0.6%+512,309+30.7%AddedHistory
CGONCG Oncology, Inc.COM733,695$27.7M0.6%00.0%UnchangedHistory
NTRANatera, Inc.COM220,000$27.9M0.6%−310,000−58.5%ReducedHistory
ISRGIntuitive Surgical IncCOM NEW58,119$28.6M0.6%−3,681−6.0%ReducedHistory
OCULOcular Therapeutix, IncCOM3,324,468$28.9M0.6%00.0%UnchangedHistory
CTNMContineum Therapeutics, Inc.CL A1,516,668$29.0M0.6%−50,000−3.2%ReducedHistory
ORKAOruka Therapeutics, Inc.COM1,235,187$30.3M0.6%+1,235,187NewHistory
PODDInsulet CorpStock142,269$33.1M0.7%+142,269NewHistory
CELCCelcuity Inc.COM2,362,279$35.2M0.8%00.0%UnchangedHistory
NAUTNautilus Biotechnology, Inc.COM12,594,211$35.9M0.8%00.0%UnchangedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM724,698$37.0M0.8%−751,505−50.9%ReducedHistory
ACRVAcrivon Therapeutics, Inc.COMMON STOCK5,360,858$37.5M0.8%00.0%UnchangedHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$42.6M0.9%00.0%UnchangedHistory
SLDBSolid Biosciences Inc.COM NEW6,906,646$48.1M1.0%00.0%UnchangedHistory
AKROAkero Therapeutics, Inc.COM1,714,806$49.2M1.1%+214,909+14.3%AddedHistory
ALDXAldeyra Therapeutics, Inc.COM9,275,851$50.0M1.1%00.0%UnchangedHistory
MGTXMeiraGTx Holdings plcCOM12,581,103$52.4M1.1%+1,250,000+11.0%AddedHistory
PTGXProtagonist Therapeutics, IncCOM1,374,563$61.9M1.3%+105,828+8.3%AddedHistory
EWTXEdgewise Therapeutics, Inc.COM2,330,294$62.2M1.3%+473,877+25.5%AddedHistory
VRDNViridian Therapeutics, Inc.COM2,812,665$64.0M1.4%+1,180,837+72.4%AddedHistory
ARGXArgenx SESPONSORED ADR118,839$64.4M1.4%+103,239+661.8%AddedHistory
PRAXPraxis Precision Medicines, Inc.COM NEW1,164,035$67.0M1.4%+413,805+55.2%AddedHistory
IMVTImmunovant, Inc.COM2,378,762$67.8M1.5%+454,976+23.7%AddedHistory
CRGXCARGO Therapeutics, Inc.COM3,683,004$68.0M1.5%00.0%UnchangedHistory
APLTApplied Therapeutics, Inc.COM8,005,000$68.0M1.5%00.0%UnchangedHistory
AXSMAxsome Therapeutics, Inc.COM782,844$70.4M1.5%+323,733+70.5%AddedHistory
ATXSAstria Therapeutics, Inc.COM6,485,420$71.4M1.5%00.0%UnchangedHistory
BHVNBiohaven Ltd.COM1,485,232$74.2M1.6%00.0%UnchangedHistory
AORTArtivion, Inc.COM2,793,703$74.4M1.6%00.0%UnchangedHistory
SYRESpyre Therapeutics, Inc.COM NEW2,872,547$84.5M1.8%−158,471−5.2%ReducedHistory
EOLSEvolus, Inc.COM5,356,622$86.8M1.9%−397,176−6.9%ReducedHistory
IMTXImmatics N.V.SHS8,086,159$92.3M2.0%00.0%UnchangedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS6,282,290$100.5M2.2%+2,348,983+59.7%AddedHistory
VKTXViking Therapeutics, Inc.COM1,699,987$107.6M2.3%+978,610+135.7%AddedHistory
APGEApogee Therapeutics, Inc.COM2,015,007$118.4M2.5%−90,629−4.3%ReducedHistory
ITCIIntra-Cellular Therapies, Inc.COM1,622,215$118.7M2.5%−94,192−5.5%ReducedHistory
SLNOSoleno Therapeutics IncCOM3,204,976$161.8M3.5%00.0%UnchangedHistory
VRNAVerona Pharma plcSPONSORED ADS6,315,933$181.7M3.9%+3,882,208+159.5%AddedHistory
RYTMRhythm Pharmaceuticals, Inc.COM3,560,214$186.5M4.0%+113,635+3.3%AddedHistory
PCVXVaxcyte, Inc.COM2,027,608$231.7M5.0%+165,000+8.9%AddedHistory
IOVAIovance Biotherapeutics, Inc.COM26,617,709$249.9M5.4%+684,567+2.6%AddedHistory
FOLDAmicus Therapeutics, Inc.COM28,057,456$299.7M6.4%00.0%UnchangedHistory

Options (5)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q3 2024
SecurityClassPutsCalls
State Street SPDR S&P Biotech ETF78464A870ETF$39.5M–
VRNAVerona Pharma plcSPONSORED ADS$7.19M$7.19M
FLNAFilana Therapeutics, Inc.COM$5.39M–
FULCFulcrum Therapeutics, Inc.COM–$5.36M
NVAXNovavax IncCOM NEW$1.26M–

Sold out since Q2 2024 (18)

Positions held at the end of Q2 2024 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q2 2024
SecurityClassShares in Q2 2024Value in Q2 2024% of portfolio in Q2 2024History
CERECerevel Therapeutics Holdings, Inc.COM10,794,876$441.4M10.7%History
MDGLMadrigal Pharmaceuticals, Inc.COM264,600$74.1M1.8%History
BBIOBridgeBio Pharma, Inc.COM1,215,346$30.8M0.7%History
CGEMCullinan Therapeutics, Inc.COM749,916$13.1M0.3%History
TEMTempus AI, Inc.CL A275,000$9.63M0.2%History
ENGNenGene Therapeutics Inc.COM800,000$7.54M0.2%History
SPRYARS Pharmaceuticals, Inc.COM867,319$7.38M0.2%History
KALVKalVista Pharmaceuticals, Inc.COM500,000$5.89M0.1%History
RXRXRecursion Pharmaceuticals, Inc.CL A769,230$5.77M0.1%History
CABACabaletta Bio, Inc.COM585,045$4.38M0.1%History
SKYESkye Bioscience, Inc.COM NEW500,000$4.00M0.1%History
FHTXFoghorn Therapeutics Inc.COM544,000$3.13M0.1%History
State Street SPDR S&P Biotech ETF78464A870ETF22,665$2.10M0.1%–
RVNCRevance Therapeutics, Inc.COM600,000$1.54M<0.1%History
EGRXEagle Pharmaceuticals, Inc.COM173,365$970.8K<0.1%History
VBIVVBI Vaccines Inc/BCCOM1,261,710$832.7K<0.1%History
TCMDTactile Systems Technology IncCOM62,639$747.9K<0.1%History
AXGNAxogen, Inc.COM30,421$220.2K<0.1%History