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Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q2 2024

Holdings as of Jun 30, 2024, filed Aug 16, 2024. Long positions only; changes compare share counts with Q1 2024.

Institution overview
Positions
107
+2 vs. Q1 2024
Portfolio value
$4.14B
−$1.53B (−27.0%) vs. Q1 2024
Filed
Aug 16, 2024
AmendedSEC
Holdings of Perceptive Advisors LLC in Q2 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
CERECerevel Therapeutics Holdings, Inc.COM10,794,876$441.4M10.7%00.0%UnchangedHistory
FOLDAmicus Therapeutics, Inc.COM28,057,456$278.3M6.7%00.0%UnchangedHistory
ACLXArcellx, Inc.COMMON STOCK3,889,739$214.7M5.2%−43,817−1.1%ReducedHistory
IOVAIovance Biotherapeutics, Inc.COM25,933,142$208.0M5.0%+6,660,151+34.6%AddedHistory
NUVLNuvalent, Inc.COM2,549,077$193.4M4.7%−234,377−8.4%ReducedHistory
RYTMRhythm Pharmaceuticals, Inc.COM3,446,579$141.5M3.4%+178,000+5.4%AddedHistory
PCVXVaxcyte, Inc.COM1,862,608$140.6M3.4%−70,151−3.6%ReducedHistory
SLNOSoleno Therapeutics IncCOM3,204,976$130.8M3.2%+130,434+4.2%AddedHistory
ITCIIntra-Cellular Therapies, Inc.COM1,716,407$117.6M2.8%+661,052+62.6%AddedHistory
IMTXImmatics N.V.SHS8,086,159$94.0M2.3%+3,503,750+76.5%AddedHistory
NBIXNeurocrine Biosciences IncStock649,909$89.5M2.2%−154,500−19.2%ReducedHistory
APGEApogee Therapeutics, Inc.COM2,105,636$82.9M2.0%+45,241+2.2%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM264,600$74.1M1.8%−165,353−38.5%ReducedHistory
AORTArtivion, Inc.COM2,793,703$71.7M1.7%+124,725+4.7%AddedHistory
SYRESpyre Therapeutics, Inc.COM NEW3,031,018$71.3M1.7%+474,339+18.6%AddedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM1,476,203$66.1M1.6%00.0%UnchangedHistory
EOLSEvolus, Inc.COM5,753,798$62.4M1.5%00.0%UnchangedHistory
SWTXSpringWorks Therapeutics, Inc.COM1,652,962$62.3M1.5%−609,500−26.9%ReducedHistory
CRGXCARGO Therapeutics, Inc.COM3,683,004$60.5M1.5%+235,000+6.8%AddedHistory
ATXSAstria Therapeutics, Inc.COM6,485,420$59.0M1.4%00.0%UnchangedHistory
NTRANatera, Inc.COM530,000$57.4M1.4%−227,225−30.0%ReducedHistory
VRCAVerrica Pharmaceuticals Inc.COM7,099,182$51.8M1.2%00.0%UnchangedHistory
BHVNBiohaven Ltd.COM1,485,232$51.6M1.2%−239,815−13.9%ReducedHistory
IMVTImmunovant, Inc.COM1,923,786$50.8M1.2%−1,039,426−35.1%ReducedHistory
MGTXMeiraGTx Holdings plcCOM11,331,103$47.7M1.2%00.0%UnchangedHistory
PTGXProtagonist Therapeutics, IncCOM1,268,735$44.0M1.1%+274,412+27.6%AddedHistory
SLDBSolid Biosciences Inc.COM NEW6,906,646$39.2M0.9%00.0%UnchangedHistory
CELCCelcuity Inc.COM2,362,279$38.7M0.9%00.0%UnchangedHistory
MDTMedtronic plcStock490,665$38.6M0.9%−938,898−65.7%ReducedHistory
VKTXViking Therapeutics, Inc.COM721,377$38.2M0.9%−272,721−27.4%ReducedHistory
APLTApplied Therapeutics, Inc.COM8,005,000$37.4M0.9%00.0%UnchangedHistory
AXSMAxsome Therapeutics, Inc.COM459,111$37.0M0.9%−646,230−58.5%ReducedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS3,933,307$35.5M0.9%+850,000+27.6%AddedHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$35.2M0.9%00.0%UnchangedHistory
VRNAVerona Pharma plcSPONSORED ADS2,433,725$35.2M0.8%−1,327,851−35.3%ReducedHistory
AKROAkero Therapeutics, Inc.COM1,499,897$35.2M0.8%+112,426+8.1%AddedHistory
EWTXEdgewise Therapeutics, Inc.COM1,856,417$33.4M0.8%−463,229−20.0%ReducedHistory
ACRVAcrivon Therapeutics, Inc.COMMON STOCK5,360,858$31.1M0.8%+2,353,000+78.2%AddedHistory
PRAXPraxis Precision Medicines, Inc.COM NEW750,230$31.0M0.7%−71,359−8.7%ReducedHistory
ADMAAdma Biologics, Inc.COM2,771,000$31.0M0.7%−3,662,369−56.9%ReducedHistory
BBIOBridgeBio Pharma, Inc.COM1,215,346$30.8M0.7%−196,687−13.9%ReducedHistory
ALDXAldeyra Therapeutics, Inc.COM9,275,851$30.7M0.7%+682,265+7.9%AddedHistory
NAUTNautilus Biotechnology, Inc.COM12,594,211$29.5M0.7%00.0%UnchangedHistory
CTNMContineum Therapeutics, Inc.CL A1,566,668$27.6M0.7%+1,566,668NewHistory
ISRGIntuitive Surgical IncCOM NEW61,800$27.5M0.7%−40,000−39.3%ReducedHistory
ARVNArvinas, Inc.COM1,027,749$27.4M0.7%−208,854−16.9%ReducedHistory
RCKTRocket Pharmaceuticals, Inc.COM1,246,597$26.8M0.6%−554,471−30.8%ReducedHistory
IRONDisc Medicine, Inc.COM553,437$24.9M0.6%−386,429−41.1%ReducedHistory
LIVNLivaNova PLCSHS444,000$24.3M0.6%+145,000+48.5%AddedHistory
CGONCG Oncology, Inc.COM733,695$23.2M0.6%−570,410−43.7%ReducedHistory
XENEXenon Pharmaceuticals Inc.COM583,256$22.7M0.5%−308,952−34.6%ReducedHistory
OCULOcular Therapeutix, IncCOM3,324,468$22.7M0.5%00.0%UnchangedHistory
PEPGPepGen Inc.COM1,410,438$22.5M0.5%00.0%UnchangedHistory
VRDNViridian Therapeutics, Inc.COM1,631,828$21.2M0.5%−2,025,271−55.4%ReducedHistory
OBIOOrchestra BioMed Holdings, Inc.COM2,545,881$20.7M0.5%00.0%UnchangedHistory
MRUSMerus N.V.COM300,000$17.8M0.4%+300,000NewHistory
RAPPRapport Therapeutics, Inc.COM748,183$17.4M0.4%+748,183NewHistory
TYRATyra Biosciences, Inc.COM1,007,367$16.1M0.4%+338,208+50.5%AddedHistory
INBXInhibrx Biosciences, Inc.COM1,064,026$15.1M0.4%+1,064,026NewHistory
ARQTArcutis Biotherapeutics, Inc.COM1,558,500$14.5M0.3%+808,500+107.8%AddedHistory
LONALeonaBio, Inc.COM5,402,964$14.3M0.3%00.0%UnchangedHistory
ZYMEZymeworks Inc.COM1,667,711$14.2M0.3%+592,904+55.2%AddedHistory
CGEMCullinan Therapeutics, Inc.COM749,916$13.1M0.3%+749,916NewHistory
PRCTPROCEPT BioRobotics CorpCOM210,659$12.9M0.3%00.0%UnchangedHistory
INSMINSMED IncCOM PAR $.01180,000$12.1M0.3%+180,000NewHistory
BCYCBicycle Therapeutics PLCSPONSORED ADS572,000$11.6M0.3%+572,000NewHistory
ICLRIcon PLCCOM31,250$9.80M0.2%+31,250NewHistory
TEMTempus AI, Inc.CL A275,000$9.63M0.2%+275,000NewHistory
AVBPArriVent BioPharma, Inc.COM415,000$7.70M0.2%00.0%UnchangedHistory
ENGNenGene Therapeutics Inc.COM800,000$7.54M0.2%−198,888−19.9%ReducedHistory
SPRYARS Pharmaceuticals, Inc.COM867,319$7.38M0.2%00.0%UnchangedHistory
ARGXArgenx SESPONSORED ADR15,600$6.71M0.2%+15,600NewHistory
ALLOAllogene Therapeutics, Inc.COM2,725,000$6.35M0.2%+2,725,000NewHistory
VERUVeru Inc.COM7,063,277$5.94M0.1%+1,478,578+26.5%AddedHistory
KALVKalVista Pharmaceuticals, Inc.COM500,000$5.89M0.1%00.0%UnchangedHistory
RXRXRecursion Pharmaceuticals, Inc.CL A769,230$5.77M0.1%+769,230NewHistory
EYPTEyePoint, Inc.COM NEW640,274$5.57M0.1%+50,628+8.6%AddedHistory
BBOTBridgeBio Oncology Therapeutics, Inc.CL A ORD SHS500,000$5.11M0.1%00.0%UnchangedHistory
MREOMereo BioPharma Group plcSPON ADS1,253,250$4.51M0.1%+1,253,250NewHistory
CABACabaletta Bio, Inc.COM585,045$4.38M0.1%−1,131,615−65.9%ReducedHistory
DTILPrecision Biosciences IncCOM NEW426,293$4.15M0.1%−54,190−11.3%ReducedHistory
SKYESkye Bioscience, Inc.COM NEW500,000$4.00M0.1%+500,000NewHistory
TRIBTrinity Biotech PLCSPONS ADR NEW1,800,000$3.83M0.1%00.0%UnchangedHistory
IRTCiRhythm Holdings, Inc.COM35,205$3.79M0.1%−210,000−85.6%ReducedHistory
LYRALyra Therapeutics, Inc.COM12,757,562$3.53M0.1%00.0%UnchangedHistory
BDSXBiodesix IncCOM2,173,880$3.33M0.1%+2,173,880NewHistory
NVNOenVVeno Medical CorpCOMMON STOCK623,315$3.27M0.1%00.0%UnchangedHistory
FHTXFoghorn Therapeutics Inc.COM544,000$3.13M0.1%+544,000NewHistory
NBTXNanobiotix S.A.SPONSORED ADS555,066$2.78M0.1%00.0%UnchangedHistory
ABSIAbsci CorpCOM700,000$2.16M0.1%00.0%UnchangedHistory
State Street SPDR S&P Biotech ETF78464A870ETF22,665$2.10M0.1%+22,665New–
XFORX4 Pharmaceuticals, IncCOM3,545,454$2.06M<0.1%00.0%UnchangedHistory
FBRXForte Biosciences, Inc.COM3,265,359$1.75M<0.1%00.0%UnchangedHistory
RVNCRevance Therapeutics, Inc.COM600,000$1.54M<0.1%00.0%UnchangedHistory
GPCRStructure Therapeutics Inc.SPONSORED ADS34,852$1.37M<0.1%+34,852NewHistory
FATEFate Therapeutics IncCOM345,575$1.13M<0.1%+345,575NewHistory
KYTXKyverna Therapeutics, Inc.COM150,000$1.13M<0.1%00.0%UnchangedHistory
EGRXEagle Pharmaceuticals, Inc.COM173,365$970.8K<0.1%+173,365NewHistory
VBIVVBI Vaccines Inc/BCCOM1,261,710$832.7K<0.1%00.0%UnchangedHistory
TCMDTactile Systems Technology IncCOM62,639$747.9K<0.1%−840,446−93.1%ReducedHistory

Options (3)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q2 2024
SecurityClassPutsCalls
IMVTImmunovant, Inc.COM–$5.28M
FLNAFilana Therapeutics, Inc.COM$2.26M–
NVAXNovavax IncCOM NEW$1.27M–

Sold out since Q1 2024 (18)

Positions held at the end of Q1 2024 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q1 2024
SecurityClassShares in Q1 2024Value in Q1 2024% of portfolio in Q1 2024History
INBXInhibrx Biosciences, Inc.COM4,256,104$148.8M2.6%History
FUSNFusion Pharmaceuticals Inc.COM6,825,395$145.5M2.6%History
SRPTSarepta Therapeutics, Inc.COM525,683$68.1M1.2%History
LABPLandos Biopharma, Inc.COM NEW1,486,991$31.9M0.6%History
TMCITreace Medical Concepts, Inc.COM2,304,954$30.1M0.5%History
AUTLAutolus Therapeutics plcSPON ADS4,330,745$27.6M0.5%History
RVMDRevolution Medicines, Inc.COM618,885$19.9M0.4%History
ABBVAbbVie Inc.Stock106,500$19.4M0.3%History
MLTXMoonLake ImmunotherapeuticsCLASS A ORD339,012$17.0M0.3%History
RAPTRAPT Therapeutics, Inc.COM1,223,472$11.0M0.2%History
MORFMorphic Holding, Inc.COM288,221$10.1M0.2%History
COGTCogent Biosciences, Inc.COM883,333$5.94M0.1%History
IBRXImmunityBio, Inc.COM1,052,887$5.65M0.1%History
MGNXMacrogenics IncCOM378,327$5.57M0.1%History
ESTAEstablishment Labs Holdings Inc.COM82,299$4.19M0.1%History
NAMSNewAmsterdam Pharma Co N.V.ORDINARY SHARES175,000$4.14M0.1%History
KURAKura Oncology, Inc.COM48,200$1.03M<0.1%History
AMLXAmylyx Pharmaceuticals, Inc.COM300,000$852.0K<0.1%History