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Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q2 2024

Holdings as of Jun 30, 2024, filed Aug 16, 2024. Long positions only; changes compare share counts with Q1 2024.

Institution overview
Positions
107
+2 vs. Q1 2024
Portfolio value
$4.14B
−$1.53B (−27.0%) vs. Q1 2024
Filed
Aug 16, 2024
AmendedSEC
Holdings of Perceptive Advisors LLC in Q2 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
CareMax, Inc.14171W111*W EXP 06/08/20260,000$846<0.1%00.0%Unchanged–
Surrozen, Inc.86889P117*W EXP 08/01/203166,666$2.77K<0.1%00.0%Unchanged–
RVMDWRevolution Medicines, Inc.*W EXP 12/17/202250,000$25.5K<0.1%00.0%UnchangedHistory
AXGNAxogen, Inc.COM30,421$220.2K<0.1%−1,523,508−98.0%ReducedHistory
CMAXCareMax, Inc.COMM STK122,643$342.2K<0.1%00.0%UnchangedHistory
OMICSingular Genomics Systems, Inc.COM NEW70,896$599.1K<0.1%00.0%UnchangedConverted for a 1-for-30 splitHistory
SYRSSyros Pharmaceuticals, Inc.COM NEW116,754$602.5K<0.1%00.0%UnchangedHistory
TCMDTactile Systems Technology IncCOM62,639$747.9K<0.1%−840,446−93.1%ReducedHistory
VBIVVBI Vaccines Inc/BCCOM1,261,710$832.7K<0.1%00.0%UnchangedHistory
EGRXEagle Pharmaceuticals, Inc.COM173,365$970.8K<0.1%+173,365NewHistory
KYTXKyverna Therapeutics, Inc.COM150,000$1.13M<0.1%00.0%UnchangedHistory
FATEFate Therapeutics IncCOM345,575$1.13M<0.1%+345,575NewHistory
GPCRStructure Therapeutics Inc.SPONSORED ADS34,852$1.37M<0.1%+34,852NewHistory
RVNCRevance Therapeutics, Inc.COM600,000$1.54M<0.1%00.0%UnchangedHistory
FBRXForte Biosciences, Inc.COM3,265,359$1.75M<0.1%00.0%UnchangedHistory
XFORX4 Pharmaceuticals, IncCOM3,545,454$2.06M<0.1%00.0%UnchangedHistory
State Street SPDR S&P Biotech ETF78464A870ETF22,665$2.10M0.1%+22,665New–
ABSIAbsci CorpCOM700,000$2.16M0.1%00.0%UnchangedHistory
NBTXNanobiotix S.A.SPONSORED ADS555,066$2.78M0.1%00.0%UnchangedHistory
FHTXFoghorn Therapeutics Inc.COM544,000$3.13M0.1%+544,000NewHistory
NVNOenVVeno Medical CorpCOMMON STOCK623,315$3.27M0.1%00.0%UnchangedHistory
BDSXBiodesix IncCOM2,173,880$3.33M0.1%+2,173,880NewHistory
LYRALyra Therapeutics, Inc.COM12,757,562$3.53M0.1%00.0%UnchangedHistory
IRTCiRhythm Holdings, Inc.COM35,205$3.79M0.1%−210,000−85.6%ReducedHistory
TRIBTrinity Biotech PLCSPONS ADR NEW1,800,000$3.83M0.1%00.0%UnchangedHistory
SKYESkye Bioscience, Inc.COM NEW500,000$4.00M0.1%+500,000NewHistory
DTILPrecision Biosciences IncCOM NEW426,293$4.15M0.1%−54,190−11.3%ReducedHistory
CABACabaletta Bio, Inc.COM585,045$4.38M0.1%−1,131,615−65.9%ReducedHistory
MREOMereo BioPharma Group plcSPON ADS1,253,250$4.51M0.1%+1,253,250NewHistory
BBOTBridgeBio Oncology Therapeutics, Inc.CL A ORD SHS500,000$5.11M0.1%00.0%UnchangedHistory
EYPTEyePoint, Inc.COM NEW640,274$5.57M0.1%+50,628+8.6%AddedHistory
RXRXRecursion Pharmaceuticals, Inc.CL A769,230$5.77M0.1%+769,230NewHistory
KALVKalVista Pharmaceuticals, Inc.COM500,000$5.89M0.1%00.0%UnchangedHistory
VERUVeru Inc.COM7,063,277$5.94M0.1%+1,478,578+26.5%AddedHistory
ALLOAllogene Therapeutics, Inc.COM2,725,000$6.35M0.2%+2,725,000NewHistory
ARGXArgenx SESPONSORED ADR15,600$6.71M0.2%+15,600NewHistory
SPRYARS Pharmaceuticals, Inc.COM867,319$7.38M0.2%00.0%UnchangedHistory
ENGNenGene Therapeutics Inc.COM800,000$7.54M0.2%−198,888−19.9%ReducedHistory
AVBPArriVent BioPharma, Inc.COM415,000$7.70M0.2%00.0%UnchangedHistory
TEMTempus AI, Inc.CL A275,000$9.63M0.2%+275,000NewHistory
ICLRIcon PLCCOM31,250$9.80M0.2%+31,250NewHistory
BCYCBicycle Therapeutics PLCSPONSORED ADS572,000$11.6M0.3%+572,000NewHistory
INSMINSMED IncCOM PAR $.01180,000$12.1M0.3%+180,000NewHistory
PRCTPROCEPT BioRobotics CorpCOM210,659$12.9M0.3%00.0%UnchangedHistory
CGEMCullinan Therapeutics, Inc.COM749,916$13.1M0.3%+749,916NewHistory
ZYMEZymeworks Inc.COM1,667,711$14.2M0.3%+592,904+55.2%AddedHistory
LONALeonaBio, Inc.COM5,402,964$14.3M0.3%00.0%UnchangedHistory
ARQTArcutis Biotherapeutics, Inc.COM1,558,500$14.5M0.3%+808,500+107.8%AddedHistory
INBXInhibrx Biosciences, Inc.COM1,064,026$15.1M0.4%+1,064,026NewHistory
TYRATyra Biosciences, Inc.COM1,007,367$16.1M0.4%+338,208+50.5%AddedHistory
RAPPRapport Therapeutics, Inc.COM748,183$17.4M0.4%+748,183NewHistory
MRUSMerus N.V.COM300,000$17.8M0.4%+300,000NewHistory
OBIOOrchestra BioMed Holdings, Inc.COM2,545,881$20.7M0.5%00.0%UnchangedHistory
VRDNViridian Therapeutics, Inc.COM1,631,828$21.2M0.5%−2,025,271−55.4%ReducedHistory
PEPGPepGen Inc.COM1,410,438$22.5M0.5%00.0%UnchangedHistory
OCULOcular Therapeutix, IncCOM3,324,468$22.7M0.5%00.0%UnchangedHistory
XENEXenon Pharmaceuticals Inc.COM583,256$22.7M0.5%−308,952−34.6%ReducedHistory
CGONCG Oncology, Inc.COM733,695$23.2M0.6%−570,410−43.7%ReducedHistory
LIVNLivaNova PLCSHS444,000$24.3M0.6%+145,000+48.5%AddedHistory
IRONDisc Medicine, Inc.COM553,437$24.9M0.6%−386,429−41.1%ReducedHistory
RCKTRocket Pharmaceuticals, Inc.COM1,246,597$26.8M0.6%−554,471−30.8%ReducedHistory
ARVNArvinas, Inc.COM1,027,749$27.4M0.7%−208,854−16.9%ReducedHistory
ISRGIntuitive Surgical IncCOM NEW61,800$27.5M0.7%−40,000−39.3%ReducedHistory
CTNMContineum Therapeutics, Inc.CL A1,566,668$27.6M0.7%+1,566,668NewHistory
NAUTNautilus Biotechnology, Inc.COM12,594,211$29.5M0.7%00.0%UnchangedHistory
ALDXAldeyra Therapeutics, Inc.COM9,275,851$30.7M0.7%+682,265+7.9%AddedHistory
BBIOBridgeBio Pharma, Inc.COM1,215,346$30.8M0.7%−196,687−13.9%ReducedHistory
ADMAAdma Biologics, Inc.COM2,771,000$31.0M0.7%−3,662,369−56.9%ReducedHistory
PRAXPraxis Precision Medicines, Inc.COM NEW750,230$31.0M0.7%−71,359−8.7%ReducedHistory
ACRVAcrivon Therapeutics, Inc.COMMON STOCK5,360,858$31.1M0.8%+2,353,000+78.2%AddedHistory
EWTXEdgewise Therapeutics, Inc.COM1,856,417$33.4M0.8%−463,229−20.0%ReducedHistory
AKROAkero Therapeutics, Inc.COM1,499,897$35.2M0.8%+112,426+8.1%AddedHistory
VRNAVerona Pharma plcSPONSORED ADS2,433,725$35.2M0.8%−1,327,851−35.3%ReducedHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$35.2M0.9%00.0%UnchangedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS3,933,307$35.5M0.9%+850,000+27.6%AddedHistory
AXSMAxsome Therapeutics, Inc.COM459,111$37.0M0.9%−646,230−58.5%ReducedHistory
APLTApplied Therapeutics, Inc.COM8,005,000$37.4M0.9%00.0%UnchangedHistory
VKTXViking Therapeutics, Inc.COM721,377$38.2M0.9%−272,721−27.4%ReducedHistory
MDTMedtronic plcStock490,665$38.6M0.9%−938,898−65.7%ReducedHistory
CELCCelcuity Inc.COM2,362,279$38.7M0.9%00.0%UnchangedHistory
SLDBSolid Biosciences Inc.COM NEW6,906,646$39.2M0.9%00.0%UnchangedHistory
PTGXProtagonist Therapeutics, IncCOM1,268,735$44.0M1.1%+274,412+27.6%AddedHistory
MGTXMeiraGTx Holdings plcCOM11,331,103$47.7M1.2%00.0%UnchangedHistory
IMVTImmunovant, Inc.COM1,923,786$50.8M1.2%−1,039,426−35.1%ReducedHistory
BHVNBiohaven Ltd.COM1,485,232$51.6M1.2%−239,815−13.9%ReducedHistory
VRCAVerrica Pharmaceuticals Inc.COM7,099,182$51.8M1.2%00.0%UnchangedHistory
NTRANatera, Inc.COM530,000$57.4M1.4%−227,225−30.0%ReducedHistory
ATXSAstria Therapeutics, Inc.COM6,485,420$59.0M1.4%00.0%UnchangedHistory
CRGXCARGO Therapeutics, Inc.COM3,683,004$60.5M1.5%+235,000+6.8%AddedHistory
SWTXSpringWorks Therapeutics, Inc.COM1,652,962$62.3M1.5%−609,500−26.9%ReducedHistory
EOLSEvolus, Inc.COM5,753,798$62.4M1.5%00.0%UnchangedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM1,476,203$66.1M1.6%00.0%UnchangedHistory
SYRESpyre Therapeutics, Inc.COM NEW3,031,018$71.3M1.7%+474,339+18.6%AddedHistory
AORTArtivion, Inc.COM2,793,703$71.7M1.7%+124,725+4.7%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM264,600$74.1M1.8%−165,353−38.5%ReducedHistory
APGEApogee Therapeutics, Inc.COM2,105,636$82.9M2.0%+45,241+2.2%AddedHistory
NBIXNeurocrine Biosciences IncStock649,909$89.5M2.2%−154,500−19.2%ReducedHistory
IMTXImmatics N.V.SHS8,086,159$94.0M2.3%+3,503,750+76.5%AddedHistory
ITCIIntra-Cellular Therapies, Inc.COM1,716,407$117.6M2.8%+661,052+62.6%AddedHistory
SLNOSoleno Therapeutics IncCOM3,204,976$130.8M3.2%+130,434+4.2%AddedHistory

Options (3)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q2 2024
SecurityClassPutsCalls
IMVTImmunovant, Inc.COM–$5.28M
FLNAFilana Therapeutics, Inc.COM$2.26M–
NVAXNovavax IncCOM NEW$1.27M–

Sold out since Q1 2024 (18)

Positions held at the end of Q1 2024 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q1 2024
SecurityClassShares in Q1 2024Value in Q1 2024% of portfolio in Q1 2024History
INBXInhibrx Biosciences, Inc.COM4,256,104$148.8M2.6%History
FUSNFusion Pharmaceuticals Inc.COM6,825,395$145.5M2.6%History
SRPTSarepta Therapeutics, Inc.COM525,683$68.1M1.2%History
LABPLandos Biopharma, Inc.COM NEW1,486,991$31.9M0.6%History
TMCITreace Medical Concepts, Inc.COM2,304,954$30.1M0.5%History
AUTLAutolus Therapeutics plcSPON ADS4,330,745$27.6M0.5%History
RVMDRevolution Medicines, Inc.COM618,885$19.9M0.4%History
ABBVAbbVie Inc.Stock106,500$19.4M0.3%History
MLTXMoonLake ImmunotherapeuticsCLASS A ORD339,012$17.0M0.3%History
RAPTRAPT Therapeutics, Inc.COM1,223,472$11.0M0.2%History
MORFMorphic Holding, Inc.COM288,221$10.1M0.2%History
COGTCogent Biosciences, Inc.COM883,333$5.94M0.1%History
IBRXImmunityBio, Inc.COM1,052,887$5.65M0.1%History
MGNXMacrogenics IncCOM378,327$5.57M0.1%History
ESTAEstablishment Labs Holdings Inc.COM82,299$4.19M0.1%History
NAMSNewAmsterdam Pharma Co N.V.ORDINARY SHARES175,000$4.14M0.1%History
KURAKura Oncology, Inc.COM48,200$1.03M<0.1%History
AMLXAmylyx Pharmaceuticals, Inc.COM300,000$852.0K<0.1%History