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Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q1 2024

Holdings as of Mar 31, 2024, filed Aug 6, 2024. Long positions only; changes compare share counts with Q4 2023.

Institution overview
Positions
105
+8 vs. Q4 2023
Portfolio value
$5.67B
+$1.20B (+26.8%) vs. Q4 2023
Filed
Aug 6, 2024
AmendedSEC
Holdings of Perceptive Advisors LLC in Q1 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
CERECerevel Therapeutics Holdings, Inc.COM10,794,876$456.3M8.0%−170,317−1.6%ReducedHistory
FOLDAmicus Therapeutics, Inc.COM28,057,456$330.5M5.8%00.0%UnchangedHistory
IOVAIovance Biotherapeutics, Inc.COM19,272,991$285.6M5.0%+7,293,576+60.9%AddedHistory
ACLXArcellx, Inc.COMMON STOCK3,933,556$273.6M4.8%−611,253−13.4%ReducedHistory
NUVLNuvalent, Inc.COM2,783,454$209.0M3.7%−134,537−4.6%ReducedHistory
INBXInhibrx Biosciences, Inc.COM4,256,104$148.8M2.6%00.0%UnchangedHistory
FUSNFusion Pharmaceuticals Inc.COM6,825,395$145.5M2.6%+4,074,000+148.1%AddedHistory
RYTMRhythm Pharmaceuticals, Inc.COM3,268,579$141.6M2.5%+1,114,469+51.7%AddedHistory
APGEApogee Therapeutics, Inc.COM2,060,395$136.9M2.4%+232,494+12.7%AddedHistory
PCVXVaxcyte, Inc.COM1,932,759$132.0M2.3%+844,273+77.6%AddedHistory
SLNOSoleno Therapeutics IncCOM3,074,542$131.6M2.3%00.0%UnchangedHistory
MDTMedtronic plcStock1,429,563$124.6M2.2%+452,911+46.4%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM429,953$114.8M2.0%+278,802+184.5%AddedHistory
SWTXSpringWorks Therapeutics, Inc.COM2,262,462$111.4M2.0%+305,216+15.6%AddedHistory
NBIXNeurocrine Biosciences IncStock804,409$110.9M2.0%+533,615+197.1%AddedHistory
SYRESpyre Therapeutics, Inc.COM NEW2,556,679$97.0M1.7%−50,000−1.9%ReducedHistory
IMVTImmunovant, Inc.COM2,963,212$95.7M1.7%+635,130+27.3%AddedHistory
BHVNBiohaven Ltd.COM1,725,047$94.3M1.7%00.0%UnchangedHistory
SLDBSolid Biosciences Inc.COM NEW6,906,646$92.0M1.6%+3,410,713+97.6%AddedHistory
ATXSAstria Therapeutics, Inc.COM6,485,420$91.2M1.6%+2,481,350+62.0%AddedHistory
AXSMAxsome Therapeutics, Inc.COM1,105,341$88.2M1.6%+67,322+6.5%AddedHistory
VKTXViking Therapeutics, Inc.COM994,098$81.5M1.4%+994,098NewHistory
EOLSEvolus, Inc.COM5,753,798$80.6M1.4%+1,790,374+45.2%AddedHistory
LYRALyra Therapeutics, Inc.COM12,757,562$79.4M1.4%00.0%UnchangedHistory
CRGXCARGO Therapeutics, Inc.COM3,448,004$77.0M1.4%+11,404+0.3%AddedHistory
ITCIIntra-Cellular Therapies, Inc.COM1,055,355$73.0M1.3%+947,355+877.2%AddedHistory
NTRANatera, Inc.COM757,225$69.3M1.2%−93,000−10.9%ReducedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM1,476,203$69.1M1.2%+220,691+17.6%AddedHistory
MGTXMeiraGTx Holdings plcCOM11,331,103$68.7M1.2%00.0%UnchangedHistory
SRPTSarepta Therapeutics, Inc.COM525,683$68.1M1.2%+73,810+16.3%AddedHistory
VRDNViridian Therapeutics, Inc.COM3,657,099$64.0M1.1%+1,926,887+111.4%AddedHistory
VRNAVerona Pharma plcSPONSORED ADS3,761,576$60.5M1.1%−104,638−2.7%ReducedHistory
IRONDisc Medicine, Inc.COM939,866$58.5M1.0%−83,179−8.1%ReducedHistory
CGONCG Oncology, Inc.COM1,304,105$57.3M1.0%+1,304,105NewHistory
AORTArtivion, Inc.COM2,668,978$56.5M1.0%+1,737,626+186.6%AddedHistory
APLTApplied Therapeutics, Inc.COM8,005,000$54.4M1.0%+3,924,751+96.2%AddedHistory
ARVNArvinas, Inc.COM1,236,603$51.0M0.9%+882,521+249.2%AddedHistory
CELCCelcuity Inc.COM2,362,279$51.0M0.9%+880,979+59.5%AddedHistory
PRAXPraxis Precision Medicines, Inc.COM NEW821,589$50.1M0.9%+821,589NewHistory
RCKTRocket Pharmaceuticals, Inc.COM1,801,068$48.5M0.9%+93,670+5.5%AddedHistory
IMTXImmatics N.V.SHS4,582,409$48.2M0.8%+1,090,909+31.2%AddedHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$47.1M0.8%00.0%UnchangedHistory
BBIOBridgeBio Pharma, Inc.COM1,412,033$43.7M0.8%−336,900−19.3%ReducedHistory
ADMAAdma Biologics, Inc.COM6,433,369$42.5M0.7%00.0%UnchangedHistory
EWTXEdgewise Therapeutics, Inc.COM2,319,646$42.3M0.7%+1,764,091+317.5%AddedHistory
VRCAVerrica Pharmaceuticals Inc.COM7,099,182$42.0M0.7%00.0%UnchangedHistory
ISRGIntuitive Surgical IncCOM NEW101,800$40.6M0.7%+46,800+85.1%AddedHistory
XENEXenon Pharmaceuticals Inc.COM892,208$38.4M0.7%−208,540−18.9%ReducedHistory
NAUTNautilus Biotechnology, Inc.COM12,594,211$37.0M0.7%00.0%UnchangedHistory
AKROAkero Therapeutics, Inc.COM1,387,471$35.0M0.6%+419,696+43.4%AddedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS3,083,307$34.8M0.6%+3,083,307NewHistory
LABPLandos Biopharma, Inc.COM NEW1,486,991$31.9M0.6%00.0%UnchangedHistory
OCULOcular Therapeutix, IncCOM3,324,468$30.3M0.5%+3,324,468NewHistory
TMCITreace Medical Concepts, Inc.COM2,304,954$30.1M0.5%+1,054,549+84.3%AddedHistory
CABACabaletta Bio, Inc.COM1,716,660$29.3M0.5%−286,398−14.3%ReducedHistory
PTGXProtagonist Therapeutics, IncCOM994,323$28.8M0.5%+611,063+159.4%AddedHistory
IRTCiRhythm Holdings, Inc.COM245,205$28.4M0.5%+245,205NewHistory
ALDXAldeyra Therapeutics, Inc.COM8,593,586$28.1M0.5%00.0%UnchangedHistory
AUTLAutolus Therapeutics plcSPON ADS4,330,745$27.6M0.5%+2,499,578+136.5%AddedHistory
ACRVAcrivon Therapeutics, Inc.COMMON STOCK3,007,858$21.5M0.4%00.0%UnchangedHistory
PEPGPepGen Inc.COM1,410,438$20.7M0.4%+1,410,438NewHistory
RVMDRevolution Medicines, Inc.COM618,885$19.9M0.4%−199,997−24.4%ReducedHistory
ABBVAbbVie Inc.Stock106,500$19.4M0.3%−131,500−55.3%ReducedHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD339,012$17.0M0.3%+256,614+311.4%AddedHistory
ENGNenGene Therapeutics Inc.COM998,888$16.9M0.3%+998,888NewHistory
LIVNLivaNova PLCSHS299,000$16.7M0.3%+299,000NewHistory
LONALeonaBio, Inc.COM5,402,964$14.8M0.3%00.0%UnchangedHistory
TCMDTactile Systems Technology IncCOM903,085$14.7M0.3%+195,926+27.7%AddedHistory
OBIOOrchestra BioMed Holdings, Inc.COM2,545,881$13.4M0.2%+113,792+4.7%AddedHistory
AXGNAxogen, Inc.COM1,553,929$12.5M0.2%+745,549+92.2%AddedHistory
EYPTEyePoint, Inc.COM NEW589,646$12.2M0.2%00.0%UnchangedHistory
ZYMEZymeworks Inc.COM1,074,807$11.3M0.2%00.0%UnchangedHistory
RAPTRAPT Therapeutics, Inc.COM1,223,472$11.0M0.2%−916,478−42.8%ReducedHistory
TYRATyra Biosciences, Inc.COM669,159$11.0M0.2%+309,159+85.9%AddedHistory
PRCTPROCEPT BioRobotics CorpCOM210,659$10.4M0.2%+210,659NewHistory
MORFMorphic Holding, Inc.COM288,221$10.1M0.2%+231,241+405.8%AddedHistory
SPRYARS Pharmaceuticals, Inc.COM867,319$8.86M0.2%+867,319NewHistory
ARQTArcutis Biotherapeutics, Inc.COM750,000$7.43M0.1%+750,000NewHistory
AVBPArriVent BioPharma, Inc.COM415,000$7.41M0.1%+415,000NewHistory
DTILPrecision Biosciences IncCOM NEW480,483$6.52M0.1%+480,483NewHistory
COGTCogent Biosciences, Inc.COM883,333$5.94M0.1%−239,625−21.3%ReducedHistory
KALVKalVista Pharmaceuticals, Inc.COM500,000$5.93M0.1%+500,000NewHistory
IBRXImmunityBio, Inc.COM1,052,887$5.65M0.1%+1,052,887NewHistory
MGNXMacrogenics IncCOM378,327$5.57M0.1%−233,605−38.2%ReducedHistory
BBOTBridgeBio Oncology Therapeutics, Inc.CL A ORD SHS500,000$5.20M0.1%+500,000NewHistory
XFORX4 Pharmaceuticals, IncCOM3,545,454$4.93M0.1%00.0%UnchangedHistory
ESTAEstablishment Labs Holdings Inc.COM82,299$4.19M0.1%00.0%UnchangedHistory
NAMSNewAmsterdam Pharma Co N.V.ORDINARY SHARES175,000$4.14M0.1%+175,000NewHistory
ABSIAbsci CorpCOM700,000$3.98M0.1%+700,000NewHistory
VERUVeru Inc.COM5,584,699$3.91M0.1%00.0%UnchangedHistory
KYTXKyverna Therapeutics, Inc.COM150,000$3.73M0.1%+150,000NewHistory
TRIBTrinity Biotech PLCSPONS ADR NEW1,800,000$3.67M0.1%+1,800,000NewHistory
NBTXNanobiotix S.A.SPONSORED ADS555,066$3.61M0.1%00.0%UnchangedHistory
NVNOenVVeno Medical CorpCOMMON STOCK623,315$3.39M0.1%00.0%UnchangedHistory
RVNCRevance Therapeutics, Inc.COM600,000$2.95M0.1%+600,000NewHistory
FBRXForte Biosciences, Inc.COM3,265,359$2.27M<0.1%00.0%UnchangedHistory
OMICSingular Genomics Systems, Inc.COM2,126,893$1.09M<0.1%00.0%UnchangedHistory
KURAKura Oncology, Inc.COM48,200$1.03M<0.1%+48,200NewHistory
AMLXAmylyx Pharmaceuticals, Inc.COM300,000$852.0K<0.1%−1,569,125−83.9%ReducedHistory
VBIVVBI Vaccines Inc/BCCOM1,261,710$757.0K<0.1%−119,645−8.7%ReducedHistory

Options (7)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q1 2024
SecurityClassPutsCalls
IRONDisc Medicine, Inc.COM$18.7M–
AMLXAmylyx Pharmaceuticals, Inc.COM–$4.77M
State Street SPDR S&P Biotech ETF78464A870ETF$4.74M–
APLTApplied Therapeutics, Inc.COM–$3.40M
NVAXNovavax IncCOM NEW$3.35M–
IMVTImmunovant, Inc.COM–$3.23M
AGIOAgios Pharmaceuticals, Inc.COM–$2.92M

Sold out since Q4 2023 (16)

Positions held at the end of Q4 2023 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q4 2023
SecurityClassShares in Q4 2023Value in Q4 2023% of portfolio in Q4 2023History
LIANYLianBioSPONSORED ADS57,558,451$257.3M5.8%History
CBAYCymaBay Therapeutics, Inc.COM4,024,400$95.1M2.1%History
RYZBRayzeBio, Inc.COM744,056$46.3M1.0%History
ASNDAscendis Pharma A/SSPONSORED ADR132,176$16.6M0.4%History
MIRMMirum Pharmaceuticals, Inc.COM534,942$15.8M0.4%History
TNGXTango Therapeutics, Inc.COM1,111,870$11.0M0.2%History
OLMAOlema Pharmaceuticals, Inc.COM539,831$7.57M0.2%History
TERNTerns Pharmaceuticals, Inc.COM1,075,000$6.98M0.2%History
RGNXREGENXBIO Inc.COM342,408$6.15M0.1%History
TVTXTravere Therapeutics, Inc.COM400,000$3.60M0.1%History
ACADAcadia Pharmaceuticals IncCOM101,000$3.16M0.1%History
CYTKCytokinetics IncCOM NEW30,317$2.53M0.1%History
KRONKronos Bio, Inc.COM1,752,745$2.19M<0.1%History
AMAMAmbrx Biopharma, Inc.COM78,811$1.12M<0.1%History
CYPHCypherpunk Technologies Inc.COM NEW44,971$186.4K<0.1%History
BCABBioAtla, Inc.COM73,000$179.6K<0.1%History