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Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q4 2023

Holdings as of Dec 31, 2023, filed Feb 26, 2024. Long positions only; changes compare share counts with Q3 2023.

Institution overview
Positions
97
+10 vs. Q3 2023
Portfolio value
$4.47B
+$1.50B (+50.4%) vs. Q3 2023
Filed
Feb 26, 2024
AmendedSEC
Holdings of Perceptive Advisors LLC in Q4 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
CERECerevel Therapeutics Holdings, Inc.COM10,965,193$464.9M10.4%+876,808+8.7%AddedHistory
FOLDAmicus Therapeutics, Inc.COM28,057,456$398.1M8.9%+364,539+1.3%AddedHistory
LIANYLianBioSPONSORED ADS57,558,451$257.3M5.8%00.0%UnchangedHistory
ACLXArcellx, Inc.COMMON STOCK4,544,809$252.2M5.6%+578,831+14.6%AddedHistory
NUVLNuvalent, Inc.COM2,917,991$214.7M4.8%+454,540+18.5%AddedHistory
INBXInhibrx Biosciences, Inc.COM4,256,104$161.7M3.6%00.0%UnchangedHistory
SLNOSoleno Therapeutics IncCOM3,074,542$123.8M2.8%00.0%UnchangedHistory
RYTMRhythm Pharmaceuticals, Inc.COM2,154,110$99.0M2.2%+1,773,282+465.6%AddedHistory
IMVTImmunovant, Inc.COM2,328,082$98.1M2.2%−1,486,609−39.0%ReducedHistory
IOVAIovance Biotherapeutics, Inc.COM11,979,415$97.4M2.2%+16,477+0.1%AddedHistory
CBAYCymaBay Therapeutics, Inc.COM4,024,400$95.1M2.1%−18,791−0.5%ReducedHistory
AXSMAxsome Therapeutics, Inc.COM1,038,019$82.6M1.8%+556,370+115.5%AddedHistory
MDTMedtronic plcStock976,652$80.5M1.8%+389,652+66.4%AddedHistory
CRGXCARGO Therapeutics, Inc.COM3,436,600$79.6M1.8%+3,436,600NewHistory
MGTXMeiraGTx Holdings plcCOM11,331,103$79.5M1.8%00.0%UnchangedHistory
VRNAVerona Pharma plcSPONSORED ADS3,866,214$76.9M1.7%−140,983−3.5%ReducedHistory
BHVNBiohaven Ltd.COM1,725,047$73.8M1.7%+973,227+129.4%AddedHistory
SWTXSpringWorks Therapeutics, Inc.COM1,957,246$71.4M1.6%+436,830+28.7%AddedHistory
BBIOBridgeBio Pharma, Inc.COM1,748,933$70.6M1.6%00.0%UnchangedHistory
PCVXVaxcyte, Inc.COM1,088,486$68.4M1.5%−254,265−18.9%ReducedHistory
LYRALyra Therapeutics, Inc.COM12,757,562$66.8M1.5%00.0%UnchangedHistory
IRONDisc Medicine, Inc.COM1,023,045$59.1M1.3%+127,404+14.2%AddedHistory
SYRESpyre Therapeutics, Inc.COM NEW2,606,679$56.1M1.3%+2,525,563+3,113.5%AddedHistory
NTRANatera, Inc.COM850,225$53.3M1.2%+632,047+289.7%AddedHistory
RAPTRAPT Therapeutics, Inc.COM2,139,950$53.2M1.2%+219,292+11.4%AddedHistory
VRCAVerrica Pharmaceuticals Inc.COM7,099,182$52.0M1.2%+2,060,199+40.9%AddedHistory
RCKTRocket Pharmaceuticals, Inc.COM1,707,398$51.2M1.1%+189,931+12.5%AddedHistory
APGEApogee Therapeutics, Inc.COM1,827,901$51.1M1.1%00.0%UnchangedHistory
XENEXenon Pharmaceuticals Inc.COM1,100,748$50.7M1.1%+483,248+78.3%AddedHistory
RYZBRayzeBio, Inc.COM744,056$46.3M1.0%−32,749−4.2%ReducedHistory
CABACabaletta Bio, Inc.COM2,003,058$45.5M1.0%+870,567+76.9%AddedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM1,255,512$44.7M1.0%−8,220−0.7%ReducedHistory
SRPTSarepta Therapeutics, Inc.COM451,873$43.6M1.0%+269,153+147.3%AddedHistory
EOLSEvolus, Inc.COM3,963,424$41.7M0.9%+2,477,623+166.8%AddedHistory
VRDNViridian Therapeutics, Inc.COM1,730,212$37.7M0.8%+719,007+71.1%AddedHistory
NAUTNautilus Biotechnology, Inc.COM12,594,211$37.7M0.8%+3,483,060+38.2%AddedHistory
ABBVAbbVie Inc.Stock238,000$36.9M0.8%+238,000NewHistory
IMTXImmatics N.V.SHS3,491,500$36.8M0.8%00.0%UnchangedHistory
NBIXNeurocrine Biosciences IncStock270,794$35.7M0.8%+111,552+70.1%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM151,151$35.0M0.8%+26,514+21.3%AddedHistory
ATXSAstria Therapeutics, Inc.COM4,004,070$30.8M0.7%+1,814,608+82.9%AddedHistory
ALDXAldeyra Therapeutics, Inc.COM8,593,586$30.2M0.7%−2,756,499−24.3%ReducedHistory
ADMAAdma Biologics, Inc.COM6,433,369$29.1M0.7%−550,950−7.9%ReducedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM1,869,125$27.5M0.6%−819,748−30.5%ReducedHistory
FUSNFusion Pharmaceuticals Inc.COM2,751,395$26.4M0.6%00.0%UnchangedHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$26.3M0.6%00.0%UnchangedHistory
RVMDRevolution Medicines, Inc.COM818,882$23.5M0.5%−502,913−38.0%ReducedHistory
AKROAkero Therapeutics, Inc.COM967,775$22.6M0.5%−651,650−40.2%ReducedHistory
OBIOOrchestra BioMed Holdings, Inc.COM2,432,089$22.2M0.5%00.0%UnchangedHistory
CELCCelcuity Inc.COM1,481,300$21.6M0.5%+1,481,300NewHistory
SLDBSolid Biosciences Inc.COM NEW3,495,933$21.5M0.5%00.0%UnchangedHistory
ISRGIntuitive Surgical IncCOM NEW55,000$18.6M0.4%+55,000NewHistory
AORTArtivion, Inc.COM931,352$16.7M0.4%00.0%UnchangedHistory
ASNDAscendis Pharma A/SSPONSORED ADR132,176$16.6M0.4%+132,176NewHistory
TMCITreace Medical Concepts, Inc.COM1,250,405$15.9M0.4%−583,655−31.8%ReducedHistory
MIRMMirum Pharmaceuticals, Inc.COM534,942$15.8M0.4%−137,100−20.4%ReducedHistory
ACRVAcrivon Therapeutics, Inc.COMMON STOCK3,007,858$14.8M0.3%00.0%UnchangedHistory
ARVNArvinas, Inc.COM354,082$14.6M0.3%+354,082NewHistory
APLTApplied Therapeutics, Inc.COM4,080,249$13.7M0.3%+4,080,249NewHistory
EYPTEyePoint, Inc.COM NEW589,646$13.6M0.3%+589,646NewHistory
LONALeonaBio, Inc.COM5,402,964$13.1M0.3%+605,686+12.6%AddedHistory
AUTLAutolus Therapeutics plcSPON ADS1,831,167$11.8M0.3%+1,831,167NewHistory
ZYMEZymeworks Inc.COM1,074,807$11.2M0.2%−371,316−25.7%ReducedHistory
TNGXTango Therapeutics, Inc.COM1,111,870$11.0M0.2%−1,307,098−54.0%ReducedHistory
TCMDTactile Systems Technology IncCOM707,159$10.1M0.2%00.0%UnchangedHistory
PTGXProtagonist Therapeutics, IncCOM383,260$8.79M0.2%−671,013−63.6%ReducedHistory
ITCIIntra-Cellular Therapies, Inc.COM108,000$7.73M0.2%+108,000NewHistory
OLMAOlema Pharmaceuticals, Inc.COM539,831$7.57M0.2%+539,831NewHistory
TERNTerns Pharmaceuticals, Inc.COM1,075,000$6.98M0.2%00.0%UnchangedHistory
COGTCogent Biosciences, Inc.COM1,122,958$6.60M0.1%−1,186,512−51.4%ReducedHistory
RGNXREGENXBIO Inc.COM342,408$6.15M0.1%+342,408NewHistory
EWTXEdgewise Therapeutics, Inc.COM555,555$6.08M0.1%+555,555NewHistory
MGNXMacrogenics IncCOM611,932$5.89M0.1%+611,932NewHistory
AXGNAxogen, Inc.COM808,380$5.52M0.1%−67,518−7.7%ReducedHistory
LABPLandos Biopharma, Inc.COM NEW1,486,991$5.44M0.1%00.0%UnchangedHistory
TYRATyra Biosciences, Inc.COM360,000$4.99M0.1%00.0%UnchangedHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD82,398$4.98M0.1%+82,398NewHistory
NBTXNanobiotix S.A.SPONSORED ADS555,066$4.04M0.1%00.0%UnchangedHistory
VERUVeru Inc.COM5,584,699$4.02M0.1%+4,494,821+412.4%AddedHistory
TVTXTravere Therapeutics, Inc.COM400,000$3.60M0.1%00.0%UnchangedHistory
NVNOenVVeno Medical CorpCOMMON STOCK623,315$3.20M0.1%−158,300−20.3%ReducedHistory
ACADAcadia Pharmaceuticals IncCOM101,000$3.16M0.1%+101,000NewHistory
XFORX4 Pharmaceuticals, IncCOM3,545,454$2.97M0.1%00.0%UnchangedHistory
FBRXForte Biosciences, Inc.COM3,265,359$2.68M0.1%00.0%UnchangedHistory
CYTKCytokinetics IncCOM NEW30,317$2.53M0.1%+30,317NewHistory
KRONKronos Bio, Inc.COM1,752,745$2.19M<0.1%00.0%UnchangedHistory
ESTAEstablishment Labs Holdings Inc.COM82,299$2.13M<0.1%−195,384−70.4%ReducedHistory
CMAXCareMax, Inc.COM CL A3,679,284$1.83M<0.1%−144,273−3.8%ReducedHistory
MORFMorphic Holding, Inc.COM56,980$1.65M<0.1%+56,980NewHistory
AMAMAmbrx Biopharma, Inc.COM78,811$1.12M<0.1%+78,811NewHistory
OMICSingular Genomics Systems, Inc.COM2,126,893$978.6K<0.1%−236,321−10.0%ReducedHistory
VBIVVBI Vaccines Inc/BCCOM1,381,355$815.0K<0.1%00.0%UnchangedHistory
CYPHCypherpunk Technologies Inc.COM NEW44,971$186.4K<0.1%00.0%UnchangedHistory
BCABBioAtla, Inc.COM73,000$179.6K<0.1%+73,000NewHistory
RVMDWRevolution Medicines, Inc.*W EXP 12/17/202250,000$82.5K<0.1%+250,000NewHistory
Surrozen, Inc.86889P117*W EXP 08/01/203166,666$3.33K<0.1%00.0%Unchanged–
CareMax, Inc.14171W111*W EXP 06/08/20260,000$450<0.1%00.0%Unchanged–

Options (4)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q4 2023
SecurityClassPutsCalls
NVAXNovavax IncCOM NEW$4.75M–
State Street SPDR S&P Biotech ETF78464A870ETF$1.28M–
APLTApplied Therapeutics, Inc.COM–$500.0K
EYPTEyePoint, Inc.COM NEW$37.5K–

Sold out since Q3 2023 (11)

Positions held at the end of Q3 2023 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q3 2023
SecurityClassShares in Q3 2023Value in Q3 2023% of portfolio in Q3 2023History
ARGXArgenx SESPONSORED ADR150,600$74.0M2.5%History
ROIVRoivant Sciences Ltd.SHS3,819,456$44.6M1.5%History
HRMYHarmony Biosciences Holdings, Inc.COM996,306$32.6M1.1%History
RLAYRelay Therapeutics, Inc.COM1,943,097$16.3M0.5%History
BMEABiomea Fusion, Inc.COM716,441$9.86M0.3%History
PRTAProthena Corp Public Ltd CoSHS165,615$7.99M0.3%History
OMOutset Medical, Inc.COM661,977$7.20M0.2%History
SLGCSomaLogic, Inc.CLASS A COM1,500,000$3.58M0.1%History
SLRNACELYRIN, Inc.COM200,000$2.03M0.1%History
MOTSMotus GI Holdings, Inc.COM NEW90,027$40.5K<0.1%History
EQRx, Inc.26886C115*W EXP 12/17/202250,000$10.0K<0.1%–